Member Publications
Jump to specific year:
72 Member Publications for October 2024
-
Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements.
- Commun Biol - published October 9, 2024
- Raimondi F, Siow KM, Wrona D, Fuster-García C, Pastukhov O, Schmitz M, Bargsten K, Kissling L, Swarts DC, Andrieux G, Cathomen T, Modlich U, Jinek M, Siler U, Reichenbach J
-
AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution.
- Nature - published October 9, 2024
- Schade AE, Perurena N, Yang Y, Rodriguez CL, Krishnan A, Gardner A, Loi P, Xu Y, Nguyen VTM, Mastellone GM, Pilla NF, Watanabe M, Ota K, Davis RA, Mattioli K, Xiang D, Zoeller JJ, Lin JR, Morganti S, Garrido-Castro AC, Tolaney SM, Li Z, Barbie DA, Sorger PK, Helin K, Santagata S, Knott SRV, Cichowski K
-
Steering research on mRNA splicing in cancer towards clinical translation.
- Nat Rev Cancer - published October 9, 2024
- Anczukow O, Allain FH, Angarola BL, Black DL, Brooks AN, Cheng C, Conesa A, Crosse EI, Eyras E, Guccione E, Lu SX, Neugebauer KM, Sehgal P, Song X, Tothova Z, Valcárcel J, Weeks KM, Yeo GW, Thomas-Tikhonenko A
-
Structural basis of μ-opioid receptor targeting by a nanobody antagonist.
- Nat Commun - published October 9, 2024
- Yu J, Kumar A, Zhang X, Martin C, Van Holsbeeck K, Raia P, Koehl A, Laeremans T, Steyaert J, Manglik A, Ballet S, Boland A, Stoeber M
-
A multispecific antibody against SARS-CoV-2 prevents immune escape in vitro and confers prophylactic protection in vivo.
- Sci Transl Med - published October 9, 2024
- Misasi J, Wei RR, Wang L, Pegu A, Wei CJ, Oloniniyi OK, Zhou T, Moliva JI, Zhao B, Choe M, Yang ES, Zhang Y, Boruszczak M, Chen M, Leung K, Li J, Yang ZY, Andersen H, Carlton K, Godbole S, Harris DR, Henry AR, Ivleva VB, Lei QP, Liu C, Longobardi L, Merriam JS, Nase D, Olia AS, Pessaint L, Porto M, Shi W, Wallace SM, Wolff JJ, Douek DC, Suthar MS, Gall JG, Koup RA, Kwong PD, Mascola JR, Nabel GJ, Sullivan NJ
-
A modular circuit coordinates the diversification of courtship strategies.
- Nature - published October 9, 2024
- Coleman RT, Morantte I, Koreman GT, Cheng ML, Ding Y, Ruta V
-
UHPLC-Q/Orbitrap HRMS combined with spectrum-effect relationship and network pharmacology to discovery the gastrointestinal motility-promoting material basis in Citri Sarcodactylis Fructus.
- J Ethnopharmacol - published October 9, 2024
- Liu X, Gong Q, Deng X, Li L, Luo R, Li X, Guo D, Deng F
-
Effects of polyphenols from Tasmannia lanceolata on structural, emulsifying, and antioxidant properties of pea protein.
- Food Chem - published October 9, 2024
- Kim W, Zia MB, Naik RR, Ho KKHY, Selomulya C
-
Capturing a methanogenic carbon monoxide dehydrogenase/acetyl-CoA synthase complex via cryogenic electron microscopy.
- Proc Natl Acad Sci U S A - published October 8, 2024
- Biester A, Grahame DA, Drennan CL
-
Mex3a Protects Against Atherosclerosis: Evidence From Mice and Humans.
- Circulation - published October 8, 2024
- Santovito D, Henderson JM, Bidzhekov K, Triantafyllidou V, Jansen Y, Chen Z, Farina FM, Diagel A, Aslani M, Blanchet X, Schunkert H, Megens RTA, Döring Y, Sattler M, Weber C
-
Enhanced Staphylococcus aureus protection by uncoupling of the α-toxin-ADAM10 interaction during murine neonatal vaccination.
- Nat Commun - published October 8, 2024
- Tomaszewski KL, Blanchard M, Olaniyi R, Brenton HR, Hayes S, Fatma F, Amarasinghe GK, Cho BK, Goo YA, DeDent AC, Fritz SA, Wardenburg JB
-
Structural basis for Vipp1 membrane binding: from loose coats and carpets to ring and rod assemblies.
- Nat Struct Mol Biol - published October 8, 2024
- Junglas B, Kartte D, Kutzner M, Hellmann N, Ritter I, Schneider D, Sachse C
-
Targeting the Hippo pathway in Schwann cells ameliorates peripheral nerve degeneration via a polypharmacological mechanism.
- Neurotherapeutics - published October 8, 2024
- Chung HJ, Nguyen TNC, Lee JW, Huh Y, Ko S, Lim H, Seo H, Ha YG, Chang JH, Woo JS, Song JJ, Kim SW, Lee JS, Mo JS, Park B, Min KW, Yoon JH, Kim MS, Jung J, Jeong NY
-
Structure of TnsABCD transpososome reveals mechanisms of targeted DNA transposition.
- Cell - published October 8, 2024
- Wang S, Siddique R, Hall MC, Rice PA, Chang L
-
Evidence for phospholipid self-organisation in concentrated ammonia-water environments.
- Biochim Biophys Acta Biomembr - published October 8, 2024
- Mackay SM, Sutherland B, Easingwood RA, Hopkins A, Bostina M, Tan EW
-
Self-assembly and condensation of intermolecular poly(UG) RNA quadruplexes.
- Nucleic Acids Res - published October 7, 2024
- Roschdi S, Montemayor EJ, Vivek R, Bingman CA, Butcher SE
-
Single-Stranded Hairpin Loop RNAs (loopmeRNAs) Potently Induce Gene Silencing through the RNA Interference Pathway.
- J Am Chem Soc - published October 7, 2024
- Aluri KC, Datta D, Waldron S, Taneja N, Qin J, Donnelly DP, Theile CS, Guenther DC, Lei L, Harp JM, Pallan PS, Egli M, Zlatev I, Manoharan M
-
Cellular NS1-BP Protein Interacts with the mRNA Export Receptor NXF1 to Mediate Nuclear Export of Influenza Virus M mRNAs.
- J Biol Chem - published October 7, 2024
- Zhang K, Cagatay T, Xie D, Angelos AE, Cornelius S, Aksenova V, Aslam S, He Z, Esparza M, Vazhavilla A, Dasso M, García-Sastre A, Ren Y, Fontoura BMA
-
The membrane curvature-inducing REEP1-4 proteins generate an ER-derived vesicular compartment.
- Nat Commun - published October 5, 2024
- Shibata Y, Mazur EE, Pan B, Paulo JA, Gygi SP, Chavan S, Valerio LSA, Zhang J, Rapoport TA
-
The VLDLR entry receptor is required for the pathogenesis of multiple encephalitic alphaviruses.
- Cell Rep - published October 5, 2024
- Palakurty S, Raju S, Sariol A, Chong Z, Wagoner N, Ma H, Zimmerman O, Adams LJ, Carmona C, Liu Z, Fremont DH, Whelan SPJ, Klimstra WB, Diamond MS
-
Experimental variables determine the outcome of RAS-RAS interactions.
- J Biol Chem - published October 5, 2024
- Zhou Z, Nguyen TL, Li X, Poujol C, Berlinska E, Michelina SV, Kapp JN, Plückthun A, Winslow MM, Ambrogio C, Shan Y, Santamaría D, Westover KD
-
NusG-Spt5 Transcription Factors: Universal, Dynamic Modulators of Gene Expression.
- J Mol Biol - published October 5, 2024
- Mooney RA, Zhu J, Saba J, Landick R
-
The role of structure in regulatory RNA elements.
- Biosci Rep - published October 4, 2024
- Tants JN, Schlundt A
-
Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model.
- Nat Commun - published October 4, 2024
- Adair BD, Field CO, Alonso JL, Xiong JP, Deng SX, Ahn HS, Mashin E, Clish CB, van Agthoven J, Yeager M, Guo Y, Tess DA, Landry DW, Poncz M, Arnaout MA
-
Shortening the early diagnostic window of Hg(2+)-induced liver injury with a H(2)O(2)-activated fluorescence/afterglow imaging assay.
- J Hazard Mater - published October 4, 2024
- Li L, Li J, Liu X, Zhao X, Zhang A, Deng Y, Peng C, Cao Z, Dehaen W, Fang Y
-
Activity and phosphatidylcholine transfer protein interactions of skeletal muscle thioesterase Them2 enable hepatic steatosis and insulin resistance.
- J Biol Chem - published October 4, 2024
- Xie Y, Liu X, Liu W, Carr LR, Lee LP, Imai N, Ortlund EA, Cohen DE
-
Exploring the energetic and conformational properties of the sequence space connecting naturally occurring RNA tetraloop receptor motifs.
- RNA - published October 3, 2024
- Shin JH, Cuevas LM, Roy R, Bonilla SL, Al-Hashimi H, Greenleaf WJ, Herschlag D
-
Interactions that define the arrangement of sugar-binding sites in BDCA-2 and dectin-2 dimers.
- Glycobiology - published October 3, 2024
- Liu Y, Kim JW, Feinberg H, Cull N, Weis WI, Taylor ME, Drickamer K
-
Long-term follow-up of givosiran treatment in patients with acute intermittent porphyria from a phase 1/2, 48-month open-label extension study.
- Orphanet J Rare Dis - published October 3, 2024
- Sardh E, Balwani M, Rees DC, Anderson KE, Jia G, Sweetser MT, Wang B
-
Regulation and signaling of the LIM domain kinases.
- Bioessays - published October 3, 2024
- Casanova-Sepúlveda G, Boggon TJ
-
Recent advances in correlative cryo-light and electron microscopy.
- Curr Opin Struct Biol - published October 3, 2024
- Pierson JA, Yang JE, Wright ER
-
Cryo-EM vs. Disease X.
- Cell - published October 3, 2024
- Coulibaly F
-
PRC2-RNA interactions: Viewpoint from Tom Cech, Chen Davidovich, and Richard Jenner.
- Mol Cell - published October 3, 2024
- Cech TR, Davidovich C, Jenner RG
-
Which cryptic sites are feasible drug targets?
- Drug Discov Today - published October 3, 2024
- Lazou M, Kozakov D, Joseph-Mccarthy D, Vajda S
-
Nature-inspired recycling of a protein mixture into a green fluorescent protein-based hydrogel.
- RSC Sustain - published October 3, 2024
- Roset Julià L, Maerkl SJ, Stellacci F
-
An interpretable deep learning framework identifies proteomic drivers of Alzheimer's disease.
- Front Cell Dev Biol - published October 2, 2024
- Panizza E, Cerione RA
-
Identification, characterization, and structure of a tRNA splicing enzyme RNA 5'-OH kinase from the pathogenic fungi Mucorales.
- RNA - published October 2, 2024
- Ghosh S, Wimberly-Gard G, Jacewicz A, Schwer B, Shuman S
-
Dramatic changes in mitochondrial subcellular location and morphology accompany activation of the CO(2) concentrating mechanism.
- Proc Natl Acad Sci U S A - published October 2, 2024
- Findinier J, Joubert LM, Fakhimi N, Schmid MF, Malkovskiy AV, Chiu W, Burlacot A, Grossman AR
-
Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons.
- Nat Biotechnol - published October 1, 2024
- Hergenreder E, Minotti AP, Zorina Y, Oberst P, Zhao Z, Munguba H, Calder EL, Baggiolini A, Walsh RM, Liston C, Levitz J, Garippa R, Chen S, Ciceri G, Studer L
-
Structural analysis and shape-based identification of novel inhibitors targeting the Trypanosoma cruzi proteasome.
- Int J Biol Macromol - published October 1, 2024
- Silva GM, Gomes SQ, Lopes CD, de Albuquerque S, de Paula da Silva CHT
-
Inherited PURA Pathogenic Variant Associated With a Mild Neurodevelopmental Disorder.
- Neurol Genet - published October 1, 2024
- Hildebrand MS, Braden RO, Lauretta ML, Kaspi A, Leventer RJ, Anderson M, Goel H, Bahlo M, Scheffer IE, Amor DJ, Janowski R, Niessing D, Morgan AT
-
Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity.
- Protein Sci - published October 1, 2024
- Narayanan D, Larsen ASG, Gauger SJ, Adafia R, Hammershøi RB, Hamborg L, Bruus-Jensen J, Griem-Krey N, Gee CL, Frølund B, Stratton MM, Kuriyan J, Kastrup JS, Langkilde AE, Wellendorph P, Solbak SMØ
-
Analysis of EGFR binding hotspots for design of new EGFR inhibitory biologics.
- Protein Sci - published October 1, 2024
- Tydings CW, Singh B, Smith AW, Ledwitch KV, Brown BP, Lovly CM, Walker AS, Meiler J
-
Ternary structure of Plasmodium vivaxN-myristoyltransferase with myristoyl-CoA and inhibitor IMP-0001173.
- Acta Crystallogr F Struct Biol Commun - published October 1, 2024
- Bolling C, Mendez A, Taylor S, Makumire S, Reers A, Zigweid R, Subramanian S, Dranow DM, Staker B, Edwards TE, Tate EW, Bell AS, Myler PJ, Asojo OA, Chakafana G
-
Alternating access of a bacterial homolog of neurotransmitter: sodium symporters determined from AlphaFold2 ensembles and DEER spectroscopy.
- Proc Natl Acad Sci U S A - published October 1, 2024
- Schwartz AC, Stein RA, Gil-Iturbe E, Quick M, Mchaourab HS
-
Structural basis for adhesin secretion by the outer-membrane usher in type 1 pili.
- Proc Natl Acad Sci U S A - published October 1, 2024
- Bitter RM, Zimmerman MI, Summers BT, Pinkner JS, Dodson KW, Hultgren SJ, Yuan P
-
Factors associated with the choice of treatment for coronoid fractures.
- Bone Joint J - published October 1, 2024
- de Klerk HH, Verweij LPE, Doornberg JN, Jaarsma RL, Murase T, Chen NC, van den Bekerom MPJ, and the Elbow Injury Management Consortium, and the Elbow Injury Management Consortium (EIMC), Al K, Ar B, Ac W, A VT, Ac AP, A T, A B, B M, B T, B J, Cs M, Cm L, Cg L, Cg T, C R, D R, Ds R, D E, E AG, E K, Et E, Gi B, Jn L, Ja W, J P, J A, K S, K S, Al B, Ms C, M M, Ml R, Mj S, N A, N W, Nwl S, P A, P M, R B, Rj T, R VR, R G, S S, Sd D, S T, T M, Y C
-
The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.
- Nat Commun - published October 1, 2024
- Álvarez L, Haubrich K, Iselin L, Gillioz L, Ruscica V, Lapouge K, Augsten S, Huppertz I, Choudhury NR, Simon B, Masiewicz P, Lethier M, Cusack S, Rittinger K, Gabel F, Leitner A, Michlewski G, Hentze MW, Allain FHT, Castello A, Hennig J
-
Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair.
- Nat Commun - published October 1, 2024
- Yu J, Yan C, Paul T, Brewer L, Tsutakawa SE, Tsai CL, Hamdan SM, Tainer JA, Ivanov I
-
Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition.
- Oncotarget - published October 1, 2024
- Rackear M, Quijano E, Ianniello Z, Colón-Ríos DA, Krysztofiak A, Abdullah R, Liu Y, Rogers FA, Ludwig DL, Dwivedi R, Bleichert F, Glazer PM
-
SARS-CoV-2 ferritin nanoparticle vaccines produce hyperimmune equine sera with broad sarbecovirus activity.
- iScience - published October 1, 2024
- Martinez EJ, Chang WC, Chen WH, Hajduczki A, Thomas PV, Jensen JL, Choe M, Sankhala RS, Peterson CE, Rees PA, Kimner J, Soman S, Kuklis C, Mendez-Rivera L, Dussupt V, King J, Corbett C, Mayer SV, Fernandes A, Murzello K, Cookenham T, Hvizdos J, Kummer L, Hart T, Lanzer K, Gambacurta J, Reagan M, Duso D, Vasan S, Collins ND, Michael NL, Krebs SJ, Gromowski GD, Modjarrad K, Kaundinya J, Joyce MG
-
Biochemical simulation of mutation synthesis and repair during SARS-CoV-2 RNA polymerization.
- Virology - published October 1, 2024
- Oo A, Chen Z, Cao D, Cho YJ, Liang B, Schinazi RF, Kim B
-
The structural landscape of Microprocessor-mediated processing of pri-let-7 miRNAs.
- Mol Cell - published October 1, 2024
- Garg A, Shang R, Cvetanovic T, Lai EC, Joshua-Tor L
-
Erratum: Studying Orthodontic Tooth Movement in Mice.
- J Vis Exp - published October 1, 2024
- Dukes MJ, Gilmore BL, Tanner JR, McDonald SM, Kelly DF
-
Fluorescent and bioluminescent bovine H5N1 influenza viruses for evaluation of antiviral interventions.
- J Virol - published October 1, 2024
- Trimarco JD, Spurrier MA, Skavicus S, Luo Z, Dutta M, Janowska K, Acharya P, Heaton BE, Heaton NS
-
Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation.
- Proc Natl Acad Sci U S A - published October 1, 2024
- Hu Y, Lopez VA, Xu H, Pfister JP, Song B, Servage KA, Sakurai M, Jones BT, Mendell JT, Wang T, Wu J, Lambowitz AM, Tomchick DR, Pawłowski K, Tagliabracci VS
-
Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses.
- Sci Adv - published October 1, 2024
- Fernández I, Bontems F, Brun D, Coquin Y, Goverde CA, Correia BE, Gessain A, Buseyne F, Rey FA, Backovic M
-
How bacteria initiate DNA replication comes into focus.
- Bioessays - published October 1, 2024
- Rashid F, Berger JM
-
Assessing Military Mental Health during the Pandemic: A Five Country Collaboration.
- Curr Psychiatry Rep - published October 1, 2024
- Lee JEC, Bennett C, Bennett N, Bouak F, Goldenberg I, Harrison K, Edge HM, Bell AM, Quartana PJ, Simms MA, Adler AB
-
Enhancing Spectrometer Performance with Unsupervised Machine Learning.
- J Phys Chem B - published October 1, 2024
- Harding BD, Hu Z, Hiett A, Delaglio F, Henzler-Wildman KA, Rienstra CM
-
Native Mass Spectrometry of Membrane Protein-Lipid Interactions in Different Detergent Environments.
- Anal Chem - published October 1, 2024
- Kumar S, Stover L, Wang L, Bahramimoghaddam H, Zhou M, Russell DH, Laganowsky A
-
Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2.
- Nat Commun - published October 1, 2024
- Scott DC, Dharuman S, Griffith E, Chai SC, Ronnebaum J, King MT, Tangallapally R, Lee C, Gee CT, Yang L, Li Y, Loudon VC, Lee HW, Ochoada J, Miller DJ, Jayasinghe T, Paulo JA, Elledge SJ, Harper JW, Chen T, Lee RE, Schulman BA
-
GoToCloud optimization of cloud computing environment for accelerating cryo-EM structure-based drug design.
- Commun Biol - published October 1, 2024
- Moriya T, Yamada Y, Yamamoto M, Senda T
-
TRPML1 gating modulation by allosteric mutations and lipids.
- Elife - published October 1, 2024
- Gan N, Han Y, Zeng W, Jiang Y
-
Characterization of conformational states of the homodimeric enzyme fluoroacetate dehalogenase by (19)F-(13)C two-dimensional NMR.
- RSC Chem Biol - published October 1, 2024
- Suleiman M, Frere GA, Törner R, Tabunar L, Bhole GV, Taverner K, Tsuchimura N, Pichugin D, Lichtenecker RJ, Vozny O, Gunning P, Arthanari H, Sljoka A, Prosser RS
-
Advances and challenges in RAS signaling targeted therapy in leukemia.
- Mol Cancer Ther - published October 1, 2024
- Chen Y, Yin Z, Westover KD, Zhou Z, Shu L
-
Molecular basis of cell membrane adaptation in daptomycin-resistant Enterococcus faecalis.
- JCI Insight - published October 1, 2024
- Nguyen AH, Tran TT, Panesso D, Hood KS, Polamraju V, Zhang R, Khan A, Miller WR, Mileykovskaya E, Shamoo Y, Xu L, Vitrac H, Arias CA
-
Chikungunya virus E2 B domain nanoparticle immunogen elicits homotypic neutralizing antibody in mice.
- Vaccine - published October 1, 2024
- Tong K, Hernandez EM, Basore K, Fremont DH, Lai JR
-
Notch induces transcription by stimulating release of paused RNA polymerase II.
- Genes Dev - published October 1, 2024
- Rogers JM, Mimoso CA, Martin BJE, Martin AP, Aster JC, Adelman K, Blacklow SC
-
Total Synthesis and Structural Reassignment of the Antitubercular Natural Product Evybactin.
- Chemistry - published October 1, 2024
- Lysenko V, Son S, Theriault ME, Slingerland CJ, Hauk G, Cleenewerk L, Speer A, Berger JM, Lewis K, Martin N
-
Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa.
- Nucleic Acids Res - published October 1, 2024
- He S, Taher NM, Simard AR, Hvorecny KL, Ragusa MJ, Bahl CD, Hickman AB, Dyda F, Madden DR
-
Mechanism of bacterial predation via ixotrophy.
- Science - published October 1, 2024
- Lien YW, Amendola D, Lee KS, Bartlau N, Xu J, Furusawa G, Polz MF, Stocker R, Weiss GL, Pilhofer M