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154 Member Publications for May 2024

Comparative effectiveness of dimethyl fumarate versus non-specific immunosuppressants: Real-world evidence from MSBase.
1. Mult Scler J Exp Transl Clin - published May 27, 2024
2. Spelman T, Eichau S, Alroughani R, Ozakbas S, Khoury SJ, Patti F, Kubala Havrdova E, Boz C, Terzi M, Kuhle J, Grammond P, Lechner-Scott J, Gray O, Amato MP, Laureys G, Shaygannejad V, Hyde R, Wang H, Bozin I, Belviso N, Quan C, Zeng F, van der Walt A, Butzkueven H, MSBase Study Group
Synthesis of 1,4-azaphosphinine nucleosides and evaluation as inhibitors of human cytidine deaminase and APOBEC3A.
1. Beilstein J Org Chem - published May 22, 2024
2. Kvach MV, Harjes S, Kurup HM, Jameson GB, Harjes E, Filichev VV
Identification of new microtubule small-molecule inhibitors and microtubule-associated genes against triple negative breast cancer.
1. Am J Cancer Res - published May 10, 2024
2. Chen J, Lin Z, Fan J, Monzavi-Karbassi B, Kelly T, Post SR, Dai L, Qin Z
Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding.
1. Nat Commun - published May 9, 2024
2. Bai H, Lewitus E, Li Y, Thomas PV, Zemil M, Merbah M, Peterson CE, Thuraisamy T, Rees PA, Hajduczki A, Dussupt V, Slike B, Mendez-Rivera L, Schmid A, Kavusak E, Rao M, Smith G, Frey J, Sims A, Wieczorek L, Polonis V, Krebs SJ, Ake JA, Vasan S, Bolton DL, Joyce MG, Townsley S, Rolland M
A prion-like domain is required for phase separation and chloroplast RNA processing during cold acclimation in Arabidopsis.
1. Plant Cell - published May 9, 2024
2. Legen J, Lenzen B, Kachariya N, Feltgen S, Gao Y, Mergenthal S, Weber W, Klotzsch E, Zoschke R, Sattler M, Schmitz-Linneweber C
Network-based elucidation of colon cancer drug resistance mechanisms by phosphoproteomic time-series analysis.
1. Nat Commun - published May 9, 2024
2. Rosenberger G, Li W, Turunen M, He J, Subramaniam PS, Pampou S, Griffin AT, Karan C, Kerwin P, Murray D, Honig B, Liu Y, Califano A
In or out of the groove? Mechanisms of lipid scrambling by TMEM16 proteins.
1. Cell Calcium - published May 9, 2024
2. Feng Z, Di Zanni E, Alvarenga O, Chakraborty S, Rychlik N, Accardi A
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors.
1. ACS Med Chem Lett - published May 9, 2024
2. Bolduc PN, Pfaffenbach M, Evans R, Xin Z, Henry KL, Gao F, Fang T, Silbereis J, Vera Rebollar J, Li P, Chodaparambil JV, Metrick C, Peterson EA
The LC3-interacting region of NBR1 is a protein interaction hub enabling optimal flux.
1. bioRxiv - published May 9, 2024
2. North BJ, Ohnstad AE, Ragusa MJ, Shoemaker CJ
The structural landscape of Microprocessor Mediated pri-let-7 miRNAs processing.
1. bioRxiv - published May 9, 2024
2. Garg A, Shang R, Cvetanovic T, Lai EC, Joshua-Tor L
The Shigella kinase effector OspG modulates host ubiquitin signaling to escape septin-cage entrapment.
1. Nat Commun - published May 8, 2024
2. Xian W, Fu J, Zhang Q, Li C, Zhao YB, Tang Z, Yuan Y, Wang Y, Zhou Y, Brzoic PS, Zheng N, Ouyang S, Luo ZQ, Liu X
Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
1. Nat Commun - published May 8, 2024
2. Martínez-Lumbreras S, Träger LK, Mulorz MM, Payr M, Dikaya V, Hipp C, König J, Sattler M
Systematic analysis of NDUFAF6 in complex I assembly and mitochondrial disease.
1. Nat Metab - published May 8, 2024
2. Sung AY, Guerra RM, Steenberge LH, Alston CL, Murayama K, Okazaki Y, Shimura M, Prokisch H, Ghezzi D, Torraco A, Carrozzo R, Rötig A, Taylor RW, Keck JL, Pagliarini DJ
Computationally restoring the potency of a clinical antibody against Omicron.
1. Nature - published May 8, 2024
2. Desautels TA, Arrildt KT, Zemla AT, Lau EY, Zhu F, Ricci D, Cronin S, Zost SJ, Binshtein E, Scheaffer SM, Dadonaite B, Petersen BK, Engdahl TB, Chen E, Handal LS, Hall L, Goforth JW, Vashchenko D, Nguyen S, Weilhammer DR, Lo JK, Rubinfeld B, Saada EA, Weisenberger T, Lee TH, Whitener B, Case JB, Ladd A, Silva MS, Haluska RM, Grzesiak EA, Earnhart CG, Hopkins S, Bates TW, Thackray LB, Segelke BW, Tri-lab COVID-19 Consortium, Lillo AM, Sundaram S, Bloom JD, Diamond MS, Crowe JE Jr, Carnahan RH, Faissol DM
Structural transitions enable interleukin-18 maturation and signaling.
1. Immunity - published May 8, 2024
2. Dong Y, Bonin JP, Devant P, Liang Z, Sever AIM, Mintseris J, Aramini JM, Du G, Gygi SP, Kagan JC, Kay LE, Wu H
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.
1. Res Sq - published May 8, 2024
2. Eisenberg D, Hou K, Ge P, Sawaya M, Dolinsky J, Yang Y, Jiang YX, Lutter L, Boyer D, Cheng X, Pi J, Zhang J, Lu J, Yang S, Yu Z, Feigon J
Domain consolidation in Bacterial 50S assembly revealed by Anti-Sense Oligonucleotide Probing.
1. bioRxiv - published May 8, 2024
2. Sheng K, Dong X, Aiyer S, Lee J, Marquardt SD, Lyumkis D, Williamson JR
Structural insights into human MHC-II association with invariant chain.
1. Proc Natl Acad Sci U S A - published May 7, 2024
2. Wang N, Waghray D, Caveney NA, Jude KM, Garcia KC
An essential and highly selective protein import pathway encoded by nucleus-forming phage.
1. Proc Natl Acad Sci U S A - published May 7, 2024
2. Morgan CJ, Enustun E, Armbruster EG, Birkholz EA, Prichard A, Forman T, Aindow A, Wannasrichan W, Peters S, Inlow K, Shepherd IL, Razavilar A, Chaikeeratisak V, Adler BA, Cress BF, Doudna JA, Pogliano K, Villa E, Corbett KD, Pogliano J
The HSV-1 pUL37 protein promotes cell invasion by regulating the kinesin-1 motor.
1. Proc Natl Acad Sci U S A - published May 7, 2024
2. Kim D, Cianfrocco MA, Verhey KJ, Smith GA
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis.
1. J Med Chem - published May 7, 2024
2. Himmelbauer MK, Bajrami B, Basile R, Capacci A, Chen T, Choi CK, Gilfillan R, Gonzalez-Lopez de Turiso F, Gu C, Hoemberger M, Johnson DS, Jones JH, Kadakia E, Kirkland M, Lin EY, Liu Y, Ma B, Magee T, Mantena S, Marx IE, Metrick CM, Mingueneau M, Murugan P, Muste CA, Nadella P, Nevalainen M, Parker Harp CR, Pattaropong V, Pietrasiewicz A, Prince RJ, Purgett TJ, Santoro JC, Schulz J, Sciabola S, Tang H, Vandeveer HG, Wang T, Yousaf Z, Helal CJ, Hopkins BT
Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus.
1. Elife - published May 7, 2024
2. Ketaren NE, Mast FD, Fridy PC, Olivier JP, Sanyal T, Sali A, Chait BT, Rout MP, Aitchison JD
Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain.
1. bioRxiv - published May 6, 2024
2. Estevam GO, Linossi EM, Macdonald CB, Espinoza CA, Michaud JM, Coyote-Maestas W, Collisson EA, Jura N, Fraser JS
Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses.
1. Nat Nanotechnol - published May 6, 2024
2. Hills RA, Tan TK, Cohen AA, Keeffe JR, Keeble AH, Gnanapragasam PNP, Storm KN, Rorick AV, West AP Jr, Hill ML, Liu S, Gilbert-Jaramillo J, Afzal M, Napier A, Admans G, James WS, Bjorkman PJ, Townsend AR, Howarth MR
Opposing polarity domains provide direction and play a role in cell division in plant growth.
1. Dev Cell - published May 6, 2024
2. Hazelwood O, Ashraf MA
Cobalamin decyanation by the membrane transporter BtuM.
1. Structure - published May 6, 2024
2. Martínez Felices JM, Barreto YB, Thangaratnarajah C, Whittaker JJ, Alencar AM, Guskov A, Slotboom DJ
A general algorithm for consensus 3D cell segmentation from 2D segmented stacks.
1. bioRxiv - published May 6, 2024
2. Zhou FY, Yapp C, Shang Z, Daetwyler S, Marin Z, Islam MT, Nanes B, Jenkins E, Gihana GM, Chang BJ, Weems A, Dustin M, Morrison S, Fiolka R, Dean K, Jamieson A, Sorger PK, Danuser G
Bispecific antibodies with broad neutralization potency against SARS-CoV-2 variants of concern.
1. bioRxiv - published May 6, 2024
2. Rubio AA, Baharani VA, Dadonaite B, Parada M, Abernathy ME, Wang Z, Lee YE, Eso MR, Phung J, Ramos I, Chen T, Nesr GE, Bloom JD, Bieniasz PD, Nussenzweig MC, Barnes CO
Structural basis for Rab6 activation by the Ric1-Rgp1 complex.
1. bioRxiv - published May 6, 2024
2. Feathers JR, Vignogna RC, Fromme JC
Ultrapotent Broadly Neutralizing Human-llama Bispecific Antibodies against HIV-1.
1. Adv Sci (Weinh) - published May 5, 2024
2. Xu J, Zhou T, McKee K, Zhang B, Liu C, Nazzari AF, Pegu A, Shen CH, Becker JE, Bender MF, Chan P, Changela A, Chaudhary R, Chen X, Einav T, Kwon YD, Lin BC, Louder MK, Merriam JS, Morano NC, O'Dell S, Olia AS, Rawi R, Roark RS, Stephens T, Teng IT, Tourtellott-Fogt E, Wang S, Yang ES, Shapiro L, Tsybovsky Y, Doria-Rose NA, Casellas R, Kwong PD
Magnetic quaternary ammonium polymer bearing porous agarose for selective extraction of Aristolochic acids in the plasma.
1. J Chromatogr A - published May 5, 2024
2. Liu X, Luo Y, Fan Y, Cao X, Lu J, Song G, Deng C
Observing one-divalent-metal-ion dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo.
1. bioRxiv - published May 5, 2024
2. Chang C, Zhou G, Gao Y
The immune interactions of gut glycans and microbiota in health and disease.
1. Mol Microbiol - published May 4, 2024
2. Demirturk M, Cinar MS, Avci FY
Structures, mechanisms and applications of RNA-centric CRISPR-Cas13.
1. Nat Chem Biol - published May 3, 2024
2. Yang H, Patel DJ
Nuclear mTOR Signaling Orchestrates Transcriptional Programs Underlying Cellular Growth and Metabolism.
1. Cells - published May 3, 2024
2. Zhao T, Fan J, Abu-Zaid A, Burley SK, Zheng XFS
TOMOMAN: a software package for large scale cryo-electron tomography data preprocessing, community data sharing, and collaborative computing.
1. bioRxiv - published May 3, 2024
2. Khavnekar S, Wan W
Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
1. Nat Commun - published May 3, 2024
2. Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P, Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X, Xiong X
Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers.
1. J Am Chem Soc - published May 3, 2024
2. Huseman ED, Lo A, Fedorova O, Elia JL, Gueble SE, Lin K, Sundaram RK, Oh J, Liu J, Menges F, Rees MG, Ronan MM, Roth JA, Batista VS, Crawford JM, Pyle AM, Bindra RS, Herzon SB
Prevalence of Slam-dependent hemophilins in Gram-negative bacteria.
1. J Bacteriol - published May 3, 2024
2. Shin HE, Pan C, Curran DM, Bateman TJ, Chong DHY, Ng D, Shah M, Moraes TF
Building up complexity in structural biology studies.
1. Nat Struct Mol Biol - published May 3, 2024
2. Nogales E
Cholesterol reduction by immunization with a PCSK9 mimic.
1. Cell Rep - published May 3, 2024
2. Zhang B, Chuang GY, Biju A, Biner D, Cheng J, Wang Y, Bao S, Chao CW, Lei H, Liu T, Nazzari AF, Yang Y, Zhou T, Chen SJ, Chen X, Kong WP, Ou L, Parchment DK, Sarfo EK, SiMa H, Todd JP, Wang S, Woodward RA, Cheng C, Rawi R, Mascola JR, Kwong PD
Imaging the Granzyme Mediated Host Immune Response to Viral and Bacterial Pathogens In Vivo Using Positron Emission Tomography.
1. ACS Infect Dis - published May 3, 2024
2. Pandey A, Chopra S, Cleary SJ, López-Álvarez M, Quimby FM, Alanizi AAA, Sakhamuri S, Zhang N, Looney MR, Craik CS, Wilson DM, Evans MJ
Multimodal mechanisms of pathogenic variants in the signal peptide of FIX leading to hemophilia B.
1. Blood Adv - published May 3, 2024
2. Gao M, Chen L, Yang J, Dong S, Cao Q, Cui Z, Dong Y, Liu H, Shen Y, Yang H, Hao Z, Zhang L, Li W, Tie JK, Shen GM
Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge.
1. NPJ Vaccines - published May 3, 2024
2. Pascha MN, Ballegeer M, Roelofs MC, Meuris L, Albulescu IC, van Kuppeveld FJM, Hurdiss DL, Bosch BJ, Zeev-Ben-Mordehai T, Saelens X, de Haan CAM
Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein.
1. Nat Commun - published May 3, 2024
2. Langedijk JPM, Cox F, Johnson NV, van Overveld D, Le L, van den Hoogen W, Voorzaat R, Zahn R, van der Fits L, Juraszek J, McLellan JS, Bakkers MJG
Quantitative trait loci mapping provides insights into the genetic regulation of dendritic cell numbers in mouse tissues.
1. Cell Rep - published May 3, 2024
2. Oliveira TY, Merkenschlager J, Eisenreich T, Bortolatto J, Yao KH, Gatti DM, Churchill GA, Nussenzweig MC, Breton G
Modulation of TMEM16B Channel Activity by the Calcium-Activated Chloride Channel Regulator 4 (CLCA4) in Human Cells.
1. J Biol Chem - published May 3, 2024
2. Sala-Rabanal M, Yurtsever Z, Berry KN, McClenaghan C, Foy AJ, Hanson A, Steinberg DF, Greven JA, Kluender CE, Alexander-Brett JM, Nichols CG, Brett TJ
scRNA-seq reveals transcriptional dynamics of Encephalitozoon intestinalis parasites in human macrophages.
1. bioRxiv - published May 3, 2024
2. Jaroenlak P, McCarty KL, Xia B, Lam C, Zwack EE, Yanai I, Bhabha G, Ekiert DC
A Humanized CB1R Yeast Biosensor Enables Facile Screening of Cannabinoid Compounds.
1. Int J Mol Sci - published May 3, 2024
2. Mulvihill CJ, Lutgens JD, Gollihar JD, Bachanová P, Tramont C, Marcotte EM, Ellington AD, Gardner EC
Mastering Death: The Roles of Viral Bcl-2 in dsDNA Viruses.
1. Viruses - published May 3, 2024
2. Suraweera CD, Espinoza B, Hinds MG, Kvansakul M
Evaluation of the RNA-dependence of PRC2 binding to chromatin in human pluripotent stem cells.
1. bioRxiv - published May 2, 2024
2. Long Y, Hwang T, Gooding AR, Goodrich KJ, Hanson SD, Vallery TK, Rinn JL, Cech TR
Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains.
1. bioRxiv - published May 2, 2024
2. Mancinelli C, Marx DC, Gonzalez-Hernandez AJ, Huynh K, Mancinelli L, Arefin A, Khelashvilli G, Levitz J, Eliezer D
Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation.
1. J Med Chem - published May 2, 2024
2. Pfaffenbach M, Bolduc PN, Xin Z, Gao F, Evans R, Fang T, Chodaparambil JV, Henry KL, Li P, Mathieu S, Metrick C, Vera Rebollar JA, Gu RF, Mccarl CA, Silbereis J, Peterson EA
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis.
1. PLoS Biol - published May 2, 2024
2. Yuan Z, van Delft MF, Li MX, Sumardy F, Smith BJ, Huang DCS, Lessene G, Khakam Y, Jin R, He S, Smith NA, Birkinshaw RW, Czabotar PE, Dewson G
Functionalizing DNA Origami by Triplex-Directed Site-Specific Photo-Cross-Linking.
1. J Am Chem Soc - published May 2, 2024
2. Kalra S, Donnelly A, Singh N, Matthews D, Del Villar-Guerra R, Bemmer V, Dominguez C, Allcock N, Cherny D, Revyakin A, Rusling DA
Structural basis of TRPV1 modulation by endogenous bioactive lipids.
1. Nat Struct Mol Biol - published May 2, 2024
2. Arnold WR, Mancino A, Moss FR 3rd, Frost A, Julius D, Cheng Y
SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23.
1. Proc Natl Acad Sci U S A - published May 2, 2024
2. Segovia D, Adams DW, Hoffman N, Safaric Tepes P, Wee TL, Cifani P, Joshua-Tor L, Krainer AR
ZEPPI: Proteome-scale sequence-based evaluation of protein-protein interaction models.
1. Proc Natl Acad Sci U S A - published May 2, 2024
2. Zhao H, Petrey D, Murray D, Honig B
Multiple inositol phosphate species enhance stability of active mTOR.
1. bioRxiv - published May 2, 2024
2. Rameh LE, York JD, Blind RD
Author Correction: Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress.
1. Nat Cancer - published May 2, 2024
2. Liu X, Viswanadhapalli S, Kumar S, Lee TK, Moore A, Ma S, Chen L, Hsieh M, Li M, Sareddy GR, Parra K, Blatt EB, Reese TC, Zhao Y, Chang A, Yan H, Xu Z, Pratap UP, Liu Z, Roggero CM, Tan Z, Weintraub ST, Peng Y, Tekmal RR, Arteaga CL, Lippincott-Schwartz J, Vadlamudi RK, Ahn JM, Raj GV
Inhibition of mRNA nuclear export promotes SARS-CoV-2 pathogenesis.
1. Proc Natl Acad Sci U S A - published May 2, 2024
2. Mei M, Cupic A, Miorin L, Ye C, Cagatay T, Zhang K, Patel K, Wilson N, McDonald WH, Crossland NA, Lo M, Rutkowska M, Aslam S, Mena I, Martinez-Sobrido L, Ren Y, García-Sastre A, Fontoura BMA
Dissecting OGT's TPR domain to identify determinants of cellular function.
1. Proc Natl Acad Sci U S A - published May 2, 2024
2. Potter SC, Gibbs BE, Hammel FA, Joiner CM, Paulo JA, Janetzko J, Levine ZG, Fei GQ, Haggarty SJ, Walker S
Matriglycan maintains t-tubule structural integrity in cardiac muscle.
1. Proc Natl Acad Sci U S A - published May 2, 2024
2. Hord JM, Anderson ME, Prouty SJ, Melton S, Gastel Z, Zimmerman K, Weiss RM, Campbell KP
Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.
1. Nat Commun - published May 2, 2024
2. Wang S, Chan KW, Wei D, Ma X, Liu S, Hu G, Park S, Pan R, Gu Y, Nazzari AF, Olia AS, Xu K, Lin BC, Louder MK, McKee K, Doria-Rose NA, Montefiori D, Seaman MS, Zhou T, Kwong PD, Arthos J, Kong XP, Lu S
Molecular insights into the prototypical single-stranded DNA-binding protein from E. coli.
1. Crit Rev Biochem Mol Biol - published May 2, 2024
2. Bonde NJ, Kozlov AG, Cox MM, Lohman TM, Keck JL
Ablation of Sam50 is associated with fragmentation and alterations in metabolism in murine and human myotubes.
1. J Cell Physiol - published May 2, 2024
2. Shao B, Killion M, Oliver A, Vang C, Zeleke F, Neikirk K, Vue Z, Garza-Lopez E, Shao JQ, Mungai M, Lam J, Williams Q, Altamura CT, Whiteside A, Kabugi K, McKenzie J, Ezedimma M, Le H, Koh A, Scudese E, Vang L, Marshall AG, Crabtree A, Tanghal JI, Stephens D, Koh HJ, Jenkins BC, Murray SA, Cooper AT, Williams C, Damo SM, McReynolds MR, Gaddy JA, Wanjalla CN, Beasley HK, Hinton A Jr
Author Correction: Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons.
1. Nat Biotechnol - published May 2, 2024
2. Hergenreder E, Minotti AP, Zorina Y, Oberst P, Zhao Z, Munguba H, Calder EL, Baggiolini A, Walsh RM, Liston C, Levitz J, Garippa R, Chen S, Ciceri G, Studer L
Publisher Correction: Histones with an unconventional DNA-binding mode in vitro are major chromatin constituents in the bacterium Bdellovibrio bacteriovorus.
1. Nat Microbiol - published May 2, 2024
2. Hocher A, Laursen SP, Radford P, Tyson J, Lambert C, Stevens KM, Montoya A, Shliaha PV, Picardeau M, Sockett RE, Luger K, Warnecke T
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling.
1. J Biol Chem - published May 2, 2024
2. Zhuang C, Yang S, Gonzalez CG, Ainsworth RI, Li S, Kobayashi MT, Wierzbicki I, Rossitto LM, Wen Y, Peti W, Stanford SM, Gonzalez DJ, Murali R, Santelli E, Bottini N
Design and Semisynthesis of Biselectrophile-Functionalized Ubiquitin Probes To Investigate Transthioesterification Reactions.
1. Org Lett - published May 2, 2024
2. Delos Reyes AMV, Lux MC, Hann ZS, Ji C, Kochańczyk T, DiBello M, Lima CD, Tan DS
MinActionPath2: path generation between different conformations of large macromolecular assemblies by action minimization.
1. Nucleic Acids Res - published May 2, 2024
2. Koehl P, Navaza R, Tekpinar M, Delarue M
Translation initiation factor eIF1.2 promotes Toxoplasma stage conversion by regulating levels of key differentiation factors.
1. Nat Commun - published May 2, 2024
2. Wang F, Holmes MJ, Hong HJ, Thaprawat P, Kannan G, Huynh MH, Schultz TL, Licon MH, Lourido S, Dong W, Brito Querido J, Sullivan WJ Jr, O'Leary SE, Carruthers VB
Advanced surface passivation for high-sensitivity studies of biomolecular condensates.
1. Proc Natl Acad Sci U S A - published May 2, 2024
2. Yao RW, Rosen MK
Patterning and folding of intestinal villi by active mesenchymal dewetting.
1. Cell - published May 2, 2024
2. Huycke TR, Häkkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, Oria R, Weaver VM, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ
Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells.
1. Nat Nanotechnol - published May 2, 2024
2. Lian X, Chatterjee S, Sun Y, Dilliard SA, Moore S, Xiao Y, Bian X, Yamada K, Sung YC, Levine RM, Mayberry K, John S, Liu X, Smith C, Johnson LT, Wang X, Zhang CC, Liu DR, Newby GA, Weiss MJ, Yen JS, Siegwart DJ
Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
1. J Med Chem - published May 2, 2024
2. Zálešák F, Nai F, Herok M, Bochenkova E, Bedi RK, Li Y, Errani F, Caflisch A
Screening Carbon Nano Materials for Preventing Amyloid Protein Aggregation by Adopting a Facile Method.
1. Cell Biochem Biophys - published May 2, 2024
2. Wilson DL, Carreon A, Chinnam S, Sharifan H, Ahlawat J, Narayan M
Benzene with Alkyl Chains Is a Universal Scaffold for Multivalent Virucidal Antivirals.
1. ACS Cent Sci - published May 2, 2024
2. Zhu Y, Gasbarri M, Zebret S, Pawar S, Mathez G, Diderich J, Valencia-Camargo AD, Russenberger D, Wang H, Silva PHJ, Dela Cruz JB, Wei L, Cagno V, Münz C, Speck RF, Desmecht D, Stellacci F
Human neutralizing antibodies target a conserved lateral patch on H7N9 hemagglutinin head.
1. Nat Commun - published May 2, 2024
2. Jia M, Zhao H, Morano NC, Lu H, Lui YM, Du H, Becker JE, Yuen KY, Ho DD, Kwong PD, Shapiro L, To KK, Wu X
Variation in structural motifs within SARS-related coronavirus spike proteins.
1. PLoS Pathog - published May 2, 2024
2. Hills FR, Eruera AR, Hodgkinson-Bean J, Jorge F, Easingwood R, Brown SHJ, Bouwer JC, Li YP, Burga LN, Bostina M
Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
1. Nat Commun - published May 2, 2024
2. Nys M, Zarkadas E, Brams M, Mehregan A, Kambara K, Kool J, Casewell NR, Bertrand D, Baenziger JE, Nury H, Ulens C
Nociceptor-immune interactomes reveal insult-specific immune signatures of pain.
1. Nat Immunol - published May 2, 2024
2. Jain A, Gyori BM, Hakim S, Jain A, Sun L, Petrova V, Bhuiyan SA, Zhen S, Wang Q, Kawaguchi R, Bunga S, Taub DG, Ruiz-Cantero MC, Tong-Li C, Andrews N, Kotoda M, Renthal W, Sorger PK, Woolf CJ
Crystalline Hepatopathy Associated With Bietti Crystalline Dystrophy: A Striking Manifestation of Disordered Fatty Acid Metabolism.
1. Am J Surg Pathol - published May 2, 2024
2. Dulken BW, Bahceci D, Leung LS, Mahajan VB, Choi WT, Tan SY
Fertility Preservation and Assisted Reproduction in Patients With Breast Cancer Interrupting Adjuvant Endocrine Therapy to Attempt Pregnancy.
1. J Clin Oncol - published May 2, 2024
2. Azim HA Jr, Niman SM, Partridge AH, Demeestere I, Ruggeri M, Colleoni M, Saura C, Shimizu C, Saetersdal AB, Kroep JR, Mailliez A, Warner E, Borges VF, Amant F, Gombos A, Kataoka A, Rousset-Jablonski C, Borstnar S, Takei J, Lee JE, Walshe JM, Ruíz-Borrego M, Moore HCF, Saunders C, Bjelic-Radisic V, Susnjar S, Cardoso F, Klar NJ, Spanic T, Ruddy K, Piccart M, Korde LA, Goldhirsch A, Gelber RD, Pagani O, Peccatori FA
mRNA Display Pipeline for Protein Biosensor Construction.
1. ACS Sens - published May 2, 2024
2. Cui Z, Ayva CE, Liew YJ, Guo Z, Mutschler R, Dreier B, Fiorito MM, Walden P, Howard CB, Ely F, Plückthun A, Pretorius C, Ungerer JP, Buckle AM, Alexandrov K
A Novel Drug Candidate for Sepsis Targeting Heparanase by Inhibiting Cytokine Storm.
1. Adv Sci (Weinh) - published May 2, 2024
2. Wang D, Wang K, Liu Q, Liu M, Zhang G, Feng K, Wang K, Ding X, Zhu H, Yang S, Liu Y, Li T, Gong P, Wang M, Wang PG, Jin H, Zhao W, Yu F
U6 snRNA m6A modification is required for accurate and efficient splicing of C. elegans and human pre-mRNAs.
1. Nucleic Acids Res - published May 2, 2024
2. Shen A, Hencel K, Parker MT, Scott R, Skukan R, Adesina AS, Metheringham CL, Miska EA, Nam Y, Haerty W, Simpson GG, Akay A
Searching for Synthetic Opioid Rescue Agents: Identification of a Potent Opioid Agonist with Reduced Respiratory Depression.
1. J Med Chem - published May 2, 2024
2. Vu LY, Luo D, Johnson K, Denehy ED, Songrady JC, Martin J, Trivedi R, Alsum AR, Shaykin JD, Chaudhary CL, Woloshin EJ, Kornberger L, Bhuiyan N, Parkin S, Jiang Q, Che T, Alilain W, Turner JR, Bardo MT, Prisinzano TE
Beyond the MUN domain, Munc13 controls priming and depriming of synaptic vesicles.
1. Cell Rep - published May 2, 2024
2. Leitz J, Wang C, Esquivies L, Pfuetzner RA, Peters JJ, Couoh-Cardel S, Wang AL, Brunger AT
Toward Artificial Peptide Nanocapsules.
1. Nanomicro Lett - published May 2, 2024
2. Wang Y, Chen B
A unifying model for membrane protein biogenesis.
1. Nat Struct Mol Biol - published May 2, 2024
2. Hegde RS, Keenan RJ
Structure-based discovery of CFTR potentiators and inhibitors.
1. Cell - published May 2, 2024
2. Liu F, Kaplan AL, Levring J, Einsiedel J, Tiedt S, Distler K, Omattage NS, Kondratov IS, Moroz YS, Pietz HL, Irwin JJ, Gmeiner P, Shoichet BK, Chen J
Structural basis for pegRNA-guided reverse transcription by a prime editor.
1. Nature - published May 2, 2024
2. Shuto Y, Nakagawa R, Zhu S, Hoki M, Omura SN, Hirano H, Itoh Y, Zhang F, Nureki O
Identification of highly potent and selective HTRA1 inhibitors.
1. Bioorg Med Chem Lett - published May 2, 2024
2. Dennis DG, Joo Sun Y, Parsons DE, Mahajan VB, Smith M
Automating biomedical literature review for rapid drug discovery: Leveraging GPT-4 to expedite pandemic response.
1. Int J Med Inform - published May 2, 2024
2. Yang J, Walker KC, Bekar-Cesaretli AA, Hao B, Bhadelia N, Joseph-McCarthy D, Paschalidis IC
N-to-S Acyl Transfer as an Enabling Strategy in Asymmetric and Chemoenzymatic Synthesis.
1. JACS Au - published May 2, 2024
2. Jo WS, Curtis BJ, Rehan M, Adrover-Castellano ML, Sherman DH, Healy AR
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses.
1. Cell Rep - published May 2, 2024
2. Cervantes Rincón T, Kapoor T, Keeffe JR, Simonelli L, Hoffmann HH, Agudelo M, Jurado A, Peace A, Lee YE, Gazumyan A, Guidetti F, Cantergiani J, Cena B, Bianchini F, Tamagnini E, Moro SG, Svoboda P, Costa F, Reis MG, Ko AI, Fallon BA, Avila-Rios S, Reyes-Téran G, Rice CM, Nussenzweig MC, Bjorkman PJ, Ruzek D, Varani L, MacDonald MR, Robbiani DF
Codon switching of conserved Ser residues in coagulation and fibrinolytic proteases.
1. J Thromb Haemost - published May 2, 2024
2. Stojanovski BM, Di Cera E
Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface.
1. Immunity - published May 2, 2024
2. Wolters RM, Ferguson JA, Nuñez IA, Chen EE, Sornberger T, Myers L, Oeverdieck S, Raghavan SSR, Kona C, Handal LS, Esilu TE, Davidson E, Doranz BJ, Engdahl TB, Kose N, Williamson LE, Creech CB, Gibson-Corley KN, Ward AB, Crowe JE Jr
Structural Determinants of Vibrio cholerae FeoB Nucleotide Promiscuity.
1. bioRxiv - published May 2, 2024
2. Lee M, Magante K, Gómez-Garzón C, Payne SM, Smith AT
A PARP2-specific active site α-helix melts to permit DNA damage-induced enzymatic activation.
1. bioRxiv - published May 2, 2024
2. Smith-Pillet ES, Billur R, Langelier MF, Talele TT, Pascal JM, Black BE
Quantitative Assessment of Morphological Changes in Lipid Droplets and Lipid-Mito Interactions with Aging in Brown Adipose.
1. bioRxiv - published May 2, 2024
2. Crabtree A, Neikirk K, Pinette J, Whiteside A, Shao B, McKenzie J, Vue Z, Vang L, Le H, Dermici M, Ahmad T, Owens TC, Oliver A, Zeleke F, Beasley HK, Lopez EG, Scudese E, Rodman T, Kabugi K, Koh A, Navarro S, Lam J, Kirk B, Mungai M, Sweetwyne M, Koh HJ, Zaganjor E, Damo SM, Gaddy JA, Kirabo A, Murray SA, Cooper A, Williams C, McReynolds MR, Marshall AG, Hinton A Jr
Identification of Small Molecule Inhibitors of PPM1D Using a Novel Drug Discovery Platform.
1. bioRxiv - published May 2, 2024
2. Jiang W, Shaw S, Rush J, Dumont N, Kim J, Singh R, Skepner A, Khodier C, Raffier C, Yan N, Schluter C, Yu X, Szuchnicki M, Sathappa M, Kahn J, Sperling AS, McKinney DC, Gould AE, Garvie CW, Miller PG
The structure of the SufS-SufE complex reveals interactions driving protected persulfide transfer in iron-sulfur cluster biogenesis.
1. bioRxiv - published May 2, 2024
2. Gogar RK, Chhikara N, Vo M, Gilbert NC, Dunkle JA, Frantom PA
Cardiolipin clustering promotes mitochondrial membrane dynamics.
1. bioRxiv - published May 2, 2024
2. Zuccaro KE, Abriata LA, Pinto Meireles FT, Moss FR 3rd, Frost A, Dal Peraro M, Aydin H
Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread.
1. bioRxiv - published May 2, 2024
2. Pahmeier F, Monticelli SR, Feng X, Hjorth CK, Wang A, Kuehne AI, Bakken RR, Batchelor TG, Lee SE, Middlecamp M, Stuart L, Abelson DM, McLellan JS, Biering SB, Herbert AS, Chandran K, Harris E
POT1 recruits and regulates CST-Polα/primase at human telomeres.
1. Cell - published May 2, 2024
2. Cai SW, Takai H, Zaug AJ, Dilgen TC, Cech TR, Walz T, de Lange T
Magnetic Susceptibility Modeling of Magic-Angle Spinning Modules for Part Per Billion Scale Field Homogeneity.
1. J Magn Reson - published May 2, 2024
2. Schönzart J, Han R, Gennett T, Rienstra CM, Stringer JA
How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins.
1. Protein Sci - published May 1, 2024
2. Baxa MC, Lin X, Mukinay CD, Chakravarthy S, Sachleben JR, Antilla S, Hartrampf N, Riback JA, Gagnon IA, Pentelute BL, Clark PL, Sosnick TR
STOPGAP: an open-source package for template matching, subtomogram alignment and classification.
1. Acta Crystallogr D Struct Biol - published May 1, 2024
2. Wan W, Khavnekar S, Wagner J
Scaling and merging macromolecular diffuse scattering with mdx2.
1. Acta Crystallogr D Struct Biol - published May 1, 2024
2. Meisburger SP, Ando N
B cell somatic hypermutation following COVID-19 vaccination with Ad26.COV2.S.
1. iScience - published May 1, 2024
2. Jacob-Dolan C, Lifton M, Powers OC, Miller J, Hachmann NP, Vu M, Surve N, Mazurek CR, Fisher JL, Rodrigues S, Patio RC, Anand T, Le Gars M, Sadoff J, Schmidt AG, Barouch DH
Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue.
1. Nat Metab - published May 1, 2024
2. Many GM, Sanford JA, Sagendorf TJ, Hou Z, Nigro P, Whytock KL, Amar D, Caputo T, Gay NR, Gaul DA, Hirshman MF, Jimenez-Morales D, Lindholm ME, Muehlbauer MJ, Vamvini M, Bergman BC, Fernández FM, Goodyear LJ, Hevener AL, Ortlund EA, Sparks LM, Xia A, Adkins JN, Bodine SC, Newgard CB, Schenk S, MoTrPAC Study Group
Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
1. Nature - published May 1, 2024
2. Son Y, Kenny TC, Khan A, Birsoy K, Hite RK
Swapping the linkers of canonical Hsp70 and Hsp110 chaperones compromises both self-association and client selection.
1. Heliyon - published May 1, 2024
2. Chakafana G, Middlemiss CJ, Zininga T, Shonhai A
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase.
1. J Chem Inf Model - published May 1, 2024
2. Cheng Z, Aitha M, Thomas CA, Sturgill A, Fairweather M, Hu A, Bethel CR, Rivera DD, Dranchak P, Thomas PW, Li H, Feng Q, Tao K, Song M, Sun N, Wang S, Silwal SB, Page RC, Fast W, Bonomo RA, Weese M, Martinez W, Inglese J, Crowder MW
A Versatile Virus-Mimetic Engineering Approach for Concurrent Protein Nanocage Surface-Functionalization and Cargo Encapsulation.
1. Small - published May 1, 2024
2. Sheng Y, Chen Z, Cherrier MV, Martin L, Bui TTT, Li W, Lynham S, Nicolet Y, Ebrahimi KH
MISATO: machine learning dataset of protein-ligand complexes for structure-based drug discovery.
1. Nat Comput Sci - published May 1, 2024
2. Siebenmorgen T, Menezes F, Benassou S, Merdivan E, Didi K, Mourão ASD, Kitel R, Liò P, Kesselheim S, Piraud M, Theis FJ, Sattler M, Popowicz GM
Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol η catalyzed DNA synthesis.
1. J Biol Chem - published May 1, 2024
2. Chang C, Zhou G, Lee Luo C, Eleraky S, Moradi M, Gao Y
Plasmid targeting and destruction by the DdmDE bacterial defence system.
1. Nature - published May 1, 2024
2. Bravo JPK, Ramos DA, Ocampo RF, Ingram C, Taylor DW
Analysis of early intermediate states of the nitrogenase reaction by regularization of EPR spectra.
1. Nat Commun - published May 1, 2024
2. Heidinger L, Perez K, Spatzal T, Einsle O, Weber S, Rees DC, Schleicher E
Fluoromethylketone-Fragment Conjugates Designed as Covalent Modifiers of EcDsbA are Atypical Substrates.
1. ChemMedChem - published May 1, 2024
2. Doak BC, Whitehouse RL, Rimmer K, Williams M, Heras B, Caria S, Ilyichova O, Vazirani M, Mohanty B, Harper JB, Scanlon MJ, Simpson JS
Antibodies expand the scope of angiotensin receptor pharmacology.
1. Nat Chem Biol - published May 1, 2024
2. Skiba MA, Sterling SM, Rawson S, Zhang S, Xu H, Jiang H, Nemeth GR, Gilman MSA, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Rockman HA, Barth P, Wingler LM, Kruse AC
IS607 TnpB is a hypercompact RNA-guided DNA endonuclease.
1. Cell Res - published May 1, 2024
2. Yang H, Patel DJ
OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization.
1. Nat Methods - published May 1, 2024
2. Ahdritz G, Bouatta N, Floristean C, Kadyan S, Xia Q, Gerecke W, O'Donnell TJ, Berenberg D, Fisk I, Zanichelli N, Zhang B, Nowaczynski A, Wang B, Stepniewska-Dziubinska MM, Zhang S, Ojewole A, Guney ME, Biderman S, Watkins AM, Ra S, Lorenzo PR, Nivon L, Weitzner B, Ban YA, Chen S, Zhang M, Li C, Song SL, He Y, Sorger PK, Mostaque E, Zhang Z, Bonneau R, AlQuraishi M
Single-molecule fluorescence multiplexing by multi-parameter spectroscopic detection of nanostructured FRET labels.
1. Nat Nanotechnol - published May 1, 2024
2. Chu J, Ejaz A, Lin KM, Joseph MR, Coraor AE, Drummond DA, Squires AH
Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines.
1. Nature - published May 1, 2024
2. Liang CY, Raju S, Liu Z, Li Y, Asthagiri Arunkumar G, Case JB, Scheaffer SM, Zost SJ, Acreman CM, Gagne M, Andrew SF, Carvalho Dos Anjos DC, Foulds KE, McLellan JS, Crowe JE Jr, Douek DC, Whelan SPJ, Elbashir SM, Edwards DK, Diamond MS
Building momentum through networks: Bioimaging across the Americas.
1. J Microsc - published May 1, 2024
2. De Niz M, Escobedo García R, Terán Ramirez C, Pakowski Y, Abonza Y, Bialy N, Orr VL, Olivera A, Abonza V, Alleva K, Allodi S, Almeida MF, Becerril Cuevas AR, Bonnet F, Burgos Solorio A, Chew TL, Chiabrando G, Cimini B, Cleret-Buhot A, Contreras Jiménez G, Daza L, De Sá V, De Val N, Delgado-Álvarez DL, Eliceiri K, Fiolka R, Grecco H, Hanein D, Hernández Herrera P, Hockberger P, Hernandez HO, Hernandez Guadarrama Y, Itano M, Jacobs CA, Jiménez-García LF, Jiménez Sabinina V, Kamaid A, Keppler A, Kumar A, Lacoste J, Lovy A, Luby-Phelps K, Mahadevan-Jansen A, Malacrida L, Mehta SB, Miller C, Miranda K, Moore JA, North A, O'Toole P, Olivares Urbano M, Pietrasanta LI, Portugal RV, Rossi AH, Sanchez Contreras J, Strambio-De-Castilla C, Soldevila G, Vale B, Vazquez D, Wood C, Brown CM, Guerrero A
Diosmetin as a promising natural therapeutic agent: In vivo, in vitro mechanisms, and clinical studies.
1. Phytother Res - published May 1, 2024
2. Sun Z, Liu K, Liang C, Wen L, Wu J, Liu X, Li X
AlphaFold2 structures guide prospective ligand discovery.
1. Science - published May 1, 2024
2. Lyu J, Kapolka N, Gumpper R, Alon A, Wang L, Jain MK, Barros-Álvarez X, Sakamoto K, Kim Y, DiBerto J, Kim K, Glenn IS, Tummino TA, Huang S, Irwin JJ, Tarkhanova OO, Moroz Y, Skiniotis G, Kruse AC, Shoichet BK, Roth BL
ASCC1 structures and bioinformatics reveal a novel Helix-Clasp-Helix RNA-binding motif linked to a two-histidine phosphodiesterase.
1. J Biol Chem - published May 1, 2024
2. Chinnam NB, Thapar R, Arvai AS, Sarker AH, Soll JM, Paul T, Syed A, Rosenberg DJ, Hammel M, Bacolla A, Katsonis P, Asthana A, Tsai MS, Ivanov I, Lichtarge O, Silverman RH, Mosammaparast N, Tsutakawa SE, Tainer JA
Differential Effects of Post-translational Modifications on the Membrane Interaction of Huntingtin Protein.
1. ACS Chem Neurosci - published May 1, 2024
2. Zhang Z, Gehin C, Abriata LA, Dal Peraro M, Lashuel H
Transcription factors ERα and Sox2 have differing multiphasic DNA and RNA binding mechanisms.
1. RNA - published May 1, 2024
2. Hemphill WO, Steiner HR, Kominsky JR, Wuttke DS, Cech TR
Multifunctional Nanofibrous Hollow Microspheres for Enhanced Periodontal Bone Regeneration.
1. Adv Sci (Weinh) - published May 1, 2024
2. Li Q, Ma C, Jing Y, Liu X
The antipyretic effect of the famous classical formula Qingwanzi Pills on a rabbit model and its serum metabolomic study.
1. J Pharm Biomed Anal - published May 1, 2024
2. Lin J, Liu X, Chen X, Yang M, Han L, Xu R, Zhang D
Liver ACOX1 regulates levels of circulating lipids that promote metabolic health through adipose remodeling.
1. Nat Commun - published May 1, 2024
2. Lu D, He A, Tan M, Mrad M, El Daibani A, Hu D, Liu X, Kleiboeker B, Che T, Hsu FF, Bambouskova M, Semenkovich CF, Lodhi IJ
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
1. Cell - published May 1, 2024
2. Williams WB, Alam SM, Ofek G, Erdmann N, Montefiori DC, Seaman MS, Wagh K, Korber B, Edwards RJ, Mansouri K, Eaton A, Cain DW, Martin M, Hwang J, Arus-Altuz A, Lu X, Cai F, Jamieson N, Parks R, Barr M, Foulger A, Anasti K, Patel P, Sammour S, Parsons RJ, Huang X, Lindenberger J, Fetics S, Janowska K, Niyongabo A, Janus BM, Astavans A, Fox CB, Mohanty I, Evangelous T, Chen Y, Berry M, Kirshner H, Van Itallie E, Saunders KO, Wiehe K, Cohen KW, McElrath MJ, Corey L, Acharya P, Walsh SR, Baden LR, Haynes BF
SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial.
1. Lancet Microbe - published May 1, 2024
2. Ober Shepherd BL, Scott PT, Hutter JN, Lee C, McCauley MD, Guzman I, Bryant C, McGuire S, Kennedy J, Chen WH, Hajduczki A, Mdluli T, Valencia-Ruiz A, Amare MF, Matyas GR, Rao M, Rolland M, Mascola JR, De Rosa SC, McElrath MJ, Montefiori DC, Serebryannyy L, McDermott AB, Peel SA, Collins ND, Joyce MG, Robb ML, Michael NL, Vasan S, Modjarrad K, EID-030 Study Group
Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models.
1. Res Sq - published May 1, 2024
2. Hertz N, Chin R, Rakhit R, Ditsworth D, Wang C, Bartholomeus J, Liu S, Mody A, Laihsu A, Eastes A, Tai C, Kim R, Li J, Khasnavis S, Rafalski V, Heerendeen D, Garda V, Phung J, de Roulet D, Ordureau A, Harper JW, Johnstone S, Stöhr J
Channel width modulates the permeability of DNA origami based nuclear pore mimics.
1. bioRxiv - published May 1, 2024
2. Feng Q, Saladin M, Wu C, Cao E, Zheng W, Zhang A, Bhardwaj P, Li X, Shen Q, Kapinos LE, Mariappan M, Lusk CP, Xiong Y, Lim RYH, Lin C
Ligand binding initiates single-molecule integrin conformational activation.
1. Cell - published May 1, 2024
2. Li J, Jo MH, Yan J, Hall T, Lee J, López-Sánchez U, Yan S, Ha T, Springer TA
A communication hub for phosphoregulation of kinetochore-microtubule attachment.
1. Curr Biol - published May 1, 2024
2. Zahm JA, Harrison SC
Missing Wedge Completion via Unsupervised Learning with Coordinate Networks.
1. Int J Mol Sci - published May 1, 2024
2. Van Veen D, Galaz-Montoya JG, Shen L, Baldwin P, Chaudhari AS, Lyumkis D, Schmid MF, Chiu W, Pauly J
Lutein and Zeaxanthin Enhance, Whereas Oxidation, Fructosylation, and Low pH Damage High-Density Lipoprotein Biological Functionality.
1. Antioxidants (Basel) - published May 1, 2024
2. Zheng J, Hong BV, Agus JK, Tang X, Klebaner NR, Chen S, Guo F, Harvey DJ, Lebrilla CB, Zivkovic AM
Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase.
1. Int J Mol Sci - published May 1, 2024
2. Schey GL, Hildebrandt ER, Wang Y, Diwan S, Passetti HA, Potts GW, Sprague-Getsy AM, Leoni ER, Kuebler TS, Sham YY, Hougland JL, Beese LS, Schmidt WK, Distefano MD
A Self-Assembling Pfs230D1-Ferritin Nanoparticle Vaccine Has Potent and Durable Malaria Transmission-Reducing Activity.
1. Vaccines (Basel) - published May 1, 2024
2. Salinas ND, Ma R, McAleese H, Ouahes T, Long CA, Miura K, Lambert LE, Tolia NH
Identification of Genes Crucial for Biological Processes in Breast Cancer Liver Metastasis Relapse.
1. Int J Mol Sci - published May 1, 2024
2. Kwok T, Yeguvapalli S, Chitrala KN
Functional characterization of single nucleotide polymorphic variants of DNA repair enzyme NEIL1 in South Asian populations.
1. DNA Repair (Amst) - published May 1, 2024
2. Zuckerman JT, Jackson AS, Minko IG, Kant M, Jaruga P, Stone MP, Dizdaroglu M, McCullough AK, Lloyd RS
RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability.
1. bioRxiv - published May 1, 2024
2. Provasek VE, Bacolla A, Rangaswamy S, Mitra J, Kodavati M, Yusuf IO, Malojirao VH, Vasquez V, Britz GW, Li GM, Xu Z, Mitra S, Garruto RM, Tainer JA, Hegde ML
Structural Basis of Aquaporin-4 Autoantibody Binding in Neuromyelitis Optica.
1. bioRxiv - published May 1, 2024
2. Gupta M, Khandelwal NK, Nelson A, Hwang P, Pourmal S, Bennett JL, Stroud RM
Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARγ.
1. bioRxiv - published May 1, 2024
2. Shang J, Kojetin DJ
Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex.
1. bioRxiv - published May 1, 2024
2. Ge T, Brickner DG, Zehr K, VanBelzen DJ, Zhang W, Caffalette C, Ungerleider S, Marcou N, Chait B, Rout MP, Brickner JH
Differential roles of putative arginine fingers of AAA(+) ATPases Rvb1 and Rvb2.
1. bioRxiv - published May 1, 2024
2. Warnock JL, Ball JA, Najmi SM, Henes M, Vazquez A, Koshnevis S, Wieden HJ, Conn GL, Ghalei H
Structure of the lens MP20 mediated adhesive junction.
1. bioRxiv - published May 1, 2024
2. Nicolas WJ, Shiriaeva A, Martynowycz MW, Grey AC, Ruma Y, Donaldson PJ, Gonen T