Member Publications

Jump to specific year:

131 Member Publications for September 2023

DNA-translocation-independent role of INO80 remodeler in DNA damage repairs.
1. J Biol Chem - published September 9, 2023
2. Sokolova V, Lee G, Mullins A, Mody P, Watanabe S, Tan D
Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet.
1. Sci Adv - published September 8, 2023
2. Iuso D, Garcia-Saez I, Couté Y, Yamaryo-Botté Y, Boeri Erba E, Adrait A, Zeaiter N, Tokarska-Schlattner M, Jilkova ZM, Boussouar F, Barral S, Signor L, Couturier K, Hajmirza A, Chuffart F, Bourova-Flin E, Vitte AL, Bargier L, Puthier D, Decaens T, Rousseaux S, Botté C, Schlattner U, Petosa C, Khochbin S
A type 2 immune circuit in the stomach controls mammalian adaptation to dietary chitin.
1. Science - published September 8, 2023
2. Kim DH, Wang Y, Jung H, Field RL, Zhang X, Liu TC, Ma C, Fraser JS, Brestoff JR, Van Dyken SJ
Methyl halide transferase-based gas reporters for quantification of filamentous bacteria in microdroplet emulsions.
1. Appl Environ Microbiol - published September 8, 2023
2. Song X, Kong SJ, Seo S, Prabhakar RG, Shamoo Y
Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) Inhibitors.
1. ACS Pharmacol Transl Sci - published September 8, 2023
2. Yuan X, Jiang H, Fu D, Rech JC, Robida A, Rajanayake K, Yuan H, He M, Wen B, Sun D, Liu C, Chinnaswamy K, Stuckey JA, Paczesny S, Yang CY
Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
1. Nat Commun - published September 7, 2023
2. Brkic A, Leibundgut M, Jablonska J, Zanki V, Car Z, Petrovic Perokovic V, Marsavelski A, Ban N, Gruic-Sovulj I
Publisher Correction: Cryo-EM structure of a RAS/RAF recruitment complex.
1. Nat Commun - published September 7, 2023
2. Park E, Rawson S, Schmoker A, Kim BW, Oh S, Song K, Jeon H, Eck MJ
Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326).
1. Front Immunol - published September 7, 2023
2. Ferguson MR, Delgado KN, McBride S, Orbe IC, La Vake CJ, Caimano MJ, Mendez Q, Moraes TF, Schryvers AB, Moody MA, Radolf JD, Weiner MP, Hawley KL
Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation.
1. Nat Microbiol - published September 7, 2023
2. Martinez M, Petit J, Leyva A, Sogues A, Megrian D, Rodriguez A, Gaday Q, Ben Assaya M, Portela MM, Haouz A, Ducret A, Grangeasse C, Alzari PM, Durán R, Wehenkel AM
Design principles for cyclin K molecular glue degraders.
1. Nat Chem Biol - published September 7, 2023
2. Kozicka Z, Suchyta DJ, Focht V, Kempf G, Petzold G, Jentzsch M, Zou C, Di Genua C, Donovan KA, Coomar S, Cigler M, Mayor-Ruiz C, Schmid-Burgk JL, Häussinger D, Winter GE, Fischer ES, Słabicki M, Gillingham D, Ebert BL, Thomä NH
Characterization of the SARS-CoV-2 BA.5.5 and BQ.1.1 Omicron variants in mice and hamsters.
1. J Virol - published September 7, 2023
2. Case JB, Scheaffer SM, Darling TL, Bricker TL, Adams LJ, Harastani HH, Trende R, Sanapala S, Fremont DH, Boon ACM, Diamond MS
Comprehensive synergy mapping links a BAF- and NSL-containing "supercomplex" to the transcriptional silencing of HIV-1.
1. Cell Rep - published September 7, 2023
2. Li Z, Deeks SG, Ott M, Greene WC
Experimental Investigation on Microstructure Alteration and Surface Morphology While Grinding 20Cr2Ni4A Gears with Different Grinding Allowance Allocation.
1. Materials (Basel) - published September 7, 2023
2. Wang R, Peng S, Zhou B, Jiang X, Li M, Gong P
The Arf-GAP Age2 localizes to the late-Golgi via a conserved amphipathic helix.
1. Mol Biol Cell - published September 6, 2023
2. Manzer KM, Fromme JC
Extending the reach of homology by using successive computational filters to find yeast pheromone genes.
1. Curr Biol - published September 6, 2023
2. Srikant S, Gaudet R, Murray AW
Overcoming lung cancer immunotherapy resistance by combining non-toxic variants of IL-12 and IL-2.
1. JCI Insight - published September 5, 2023
2. Horton BL, D'Souza AD, Zagorulya M, McCreery CV, Abhiraman GC, Picton LK, Sheen A, Agarwal Y, Momin N, Wittrup KD, White FM, Garcia KC, Spranger S
Manipulating PTPRD function with ectodomain antibodies.
1. Genes Dev - published September 5, 2023
2. Qian Z, Song D, Ipsaro JJ, Bautista C, Joshua-Tor L, Yeh JT, Tonks NK
Lignans as multi-targeted natural products in neurodegenerative diseases and depression: Recent perspectives.
1. Phytother Res - published September 5, 2023
2. Li Z, Zheng Y, Liu K, Liang Y, Lu J, Li Q, Zhao B, Liu X, Li X
Reinvestigating the Synthesis and Characterization of Ethyl 3-[5-(2-Ethoxycarbonyl-1-methylvinyloxy)-1-methyl-1H-indol-3-yl]-but-2-enoate.
1. ACS Omega - published September 5, 2023
2. Li NS, Piccirilli JA, Greene GL
A synthetic delivery vector for mucosal vaccination.
1. Biomaterials - published September 5, 2023
2. Billet A, Hadjerci J, Tran T, Kessler P, Ulmer J, Mourier G, Ghazarian M, Gonzalez A, Thai R, Urquia P, Van Baelen AC, Meola A, Fernandez I, Deville-Foillard S, MacDonald E, Paolini L, Schmidt F, Rey FA, Kay MS, Tartour E, Servent D, Johannes L
Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin.
1. J Cell Biol - published September 4, 2023
2. Kumar S, Neal ML, Li S, Navare AT, Van Eeuwen T, Wozniak RW, Mast FD, Rout MP, Aitchison JD
Memory B cell development elicited by mRNA booster vaccinations in the elderly.
1. J Exp Med - published September 4, 2023
2. Wang Z, Muecksch F, Raspe R, Johannsen F, Turroja M, Canis M, ElTanbouly MA, Santos GSS, Johnson B, Baharani VA, Patejak R, Yao KH, Chirco BJ, Millard KG, Shimeliovich I, Gazumyan A, Oliveira TY, Bieniasz PD, Hatziioannou T, Caskey M, Nussenzweig MC
Identification of the bacteriophage nucleus protein interaction network.
1. Nat Struct Mol Biol - published September 4, 2023
2. Enustun E, Deep A, Gu Y, Nguyen KT, Chaikeeratisak V, Armbruster E, Ghassemian M, Villa E, Pogliano J, Corbett KD
Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity.
1. Nucleic Acids Res - published September 4, 2023
2. Syed A, Filandr F, Patterson-Fortin J, Bacolla A, Ravindranathan R, Zhou J, McDonald DT, Albuhluli ME, Verway-Cohen A, Newman JA, Tsai MS, Jones DE, Schriemer DC, D'Andrea AD, Tainer JA
Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
1. Nat Commun - published September 4, 2023
2. Campagne S, Jutzi D, Malard F, Matoga M, Romane K, Feldmuller M, Colombo M, Ruepp MD, Allain FH
Two-photon fluorescence lifetime imaging microscopy of NADH metabolism in HIV-1 infected cells and tissues.
1. Front Immunol - published September 4, 2023
2. Snyder GA, Kumar S, Lewis GK, Ray K
The NADH recycling enzymes TsaC and TsaD regenerate reducing equivalents for Rieske oxygenase chemistry.
1. J Biol Chem - published September 4, 2023
2. Tian J, Boggs DG, Donnan PH, Barroso GT, Garcia AA, Dowling DP, Buss JA, Bridwell-Rabb J
Assessing immunogenicity barriers of the HIV-1 envelope trimer.
1. NPJ Vaccines - published September 3, 2023
2. Maliqi L, Friedrich N, Glögl M, Schmutz S, Schmidt D, Rusert P, Schanz M, Zaheri M, Pasin C, Niklaus C, Foulkes C, Reinberg T, Dreier B, Abela I, Peterhoff D, Hauser A, Kouyos RD, Günthard HF, van Gils MJ, Sanders RW, Wagner R, Plückthun A, Trkola A
Tetraspanins: structure, dynamics, and principles of partner-protein recognition.
1. Trends Cell Biol - published September 3, 2023
2. Susa KJ, Kruse AC, Blacklow SC
Autoinhibited kinesin-1 adopts a hierarchical folding pattern.
1. bioRxiv - published September 2, 2023
2. Tan Z, Yue Y, da Veiga Leprevost F, Haynes SE, Basrur V, Nesvizhskii AI, Verhey KJ, Cianfrocco MA
Structural advances toward understanding the catalytic activity and conformational dynamics of modular nonribosomal peptide synthetases.
1. Nat Prod Rep - published September 2, 2023
2. Patel KD, MacDonald MR, Ahmed SF, Singh J, Gulick AM
Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
1. Nat Commun - published September 2, 2023
2. Patel PN, Dickey TH, Diouf A, Salinas ND, McAleese H, Ouahes T, Long CA, Miura K, Lambert LE, Tolia NH
Selective steroidogenic cytochrome P450 haem iron ligation by steroid-derived isonitriles.
1. Commun Chem - published September 2, 2023
2. Richard AM, Wong NR, Harris K, Sundar R, Scott EE, Pochapsky TC
Finding a window for gene therapy for hereditary deafness.
1. Proc Natl Acad Sci U S A - published September 2, 2023
2. Ivanchenko MV, Corey DP
Iditarod, a Drosophila homolog of the Irisin precursor FNDC5, is critical for exercise performance and cardiac autophagy.
1. Proc Natl Acad Sci U S A - published September 2, 2023
2. Cobb T, Hwang I, Soukar M, Namkoong S, Cho US, Safdar M, Kim M, Wessells RJ, Lee JH
Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants.
1. J Clin Microbiol - published September 2, 2023
2. Rao A, Westbrook A, Bassit L, Parsons R, Fitts E, Greenleaf M, McLendon K, Sullivan JA, O'Sick W, Baugh T, Bowers HB, Frank F, Wang E, Le M, Frediani J, Roychoudhury P, Greninger AL, Jerris R, Pollock NR, Ortlund EA, Roback JD, Lam WA, Piantadosi A
Custom tuning of Rieske oxygenase reactivity.
1. Nat Commun - published September 2, 2023
2. Tian J, Liu J, Knapp M, Donnan PH, Boggs DG, Bridwell-Rabb J
TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence.
1. Sci Transl Med - published September 2, 2023
2. Wu G, Yoshida N, Liu J, Zhang X, Xiong Y, Heavican-Foral TB, Mandato E, Liu H, Nelson GM, Yang L, Chen R, Donovan KA, Jones MK, Roshal M, Zhang Y, Xu R, Nirmal AJ, Jain S, Leahy C, Jones KL, Stevenson KE, Galasso N, Ganesan N, Chang T, Wu WC, Louissaint A, Debaize L, Yoon H, Dal Cin P, Chan WC, Ho Sui SJ, Ng SY, Feldman AL, Horwitz SM, Adelman K, Fischer ES, Chen CW, Weinstock DM, Brown M
CFTR Folding: From Structure and Proteostasis to Cystic Fibrosis Personalized Medicine.
1. ACS Chem Biol - published September 2, 2023
2. McDonald EF, Meiler J, Plate L
Structural basis for the activation of a compact CRISPR-Cas13 nuclease.
1. Nat Commun - published September 2, 2023
2. Deng X, Osikpa E, Yang J, Oladeji SJ, Smith J, Gao X, Gao Y
Acetyl-methyllysine marks chromatin at active transcription start sites.
1. Nature - published September 2, 2023
2. Lu-Culligan WJ, Connor LJ, Xie Y, Ekundayo BE, Rose BT, Machyna M, Pintado-Urbanc AP, Zimmer JT, Vock IW, Bhanu NV, King MC, Garcia BA, Bleichert F, Simon MD
Structural basis for inactivation of PRC2 by G-quadruplex RNA.
1. Science - published September 2, 2023
2. Song J, Gooding AR, Hemphill WO, Love BD, Robertson A, Yao L, Zon LI, North TE, Kasinath V, Cech TR
Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.
1. Nat Chem Biol - published September 2, 2023
2. Schmidheini L, Mathis N, Marquart KF, Rothgangl T, Kissling L, Böck D, Chanez C, Wang JP, Jinek M, Schwank G
Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
1. Nat Struct Mol Biol - published September 2, 2023
2. Bodrug T, Welsh KA, Bolhuis DL, Paulаkonis E, Martinez-Chacin RC, Liu B, Pinkin N, Bonacci T, Cui L, Xu P, Roscow O, Amann SJ, Grishkovskaya I, Emanuele MJ, Harrison JS, Steimel JP, Hahn KM, Zhang W, Zhong ED, Haselbach D, Brown NG
The importance of patient-partnered research in addressing long COVID: Takeaways for biomedical research study design from the RECOVER Initiative's Mechanistic Pathways taskforce.
1. Elife - published September 2, 2023
2. Kim C, Chen B, Mohandas S, Rehman J, Sherif ZA, Coombs K, RECOVER Mechanistic Pathways Task Force, RECOVER Initiative
Characterisation of TbSmee1 suggests endocytosis allows surface-bound cargo to enter the trypanosome flagellar pocket.
1. J Cell Sci - published September 2, 2023
2. Schichler D, Konle A, Spath EM, Riegler S, Klein A, Seleznev A, Jung S, Wuppermann T, Wetterich N, Borges A, Meyer-Natus E, Havlicek K, Cabrera SP, Niedermüller K, Sajko S, Dohn M, Malzer X, Riemer E, Tumurbaatar T, Djinovic-Carugo K, Dong G, Janzen CJ, Morriswood B
Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope.
1. J Virol - published September 2, 2023
2. McCool RS, Musayev M, Bush SM, Derrien-Colemyn A, Acreman CM, Wrapp D, Ruckwardt TJ, Graham BS, Mascola JR, McLellan JS
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG.
1. Nat Commun - published September 2, 2023
2. Kugler E, Madiwale S, Yong D, Thoms JAI, Birger Y, Sykes DB, Schmoellerl J, Drakul A, Priebe V, Yassin M, Aqaqe N, Rein A, Fishman H, Geron I, Chen CW, Raught B, Liu Q, Ogana H, Liedke E, Bourquin JP, Zuber J, Milyavsky M, Pimanda J, Privé GG, Izraeli S
Author Correction: Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection.
1. Nat Commun - published September 2, 2023
2. Slough MM, Li R, Herbert AS, Lasso G, Kuehne AI, Monticelli SR, Bakken RR, Liu Y, Ghosh A, Moreau AM, Zeng X, Rey FA, Guardado-Calvo P, Almo SC, Dye JM, Jangra RK, Wang Z, Chandran K
Implications of a multiscale structure of the yeast nuclear pore complex.
1. Mol Cell - published September 2, 2023
2. Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP
Stereotactic Body Radiation Therapy versus Conventional External Beam Radiotherapy for Spinal Metastases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
1. Radiother Oncol - published September 2, 2023
2. C Y Wong H, Fung Lee S, Wai Chan A, Caini S, Hoskin P, Simone Ii CB, Johnstone P, van der Linden Y, van der Velden JM, Martin E, Alcorn S, Johnstone C, Isabelle Choi J, Nader Marta G, Oldenburger E, Raman S, Rembielak A, Vassiliou V, Bonomo P, Nguyen QN, Chow E, Ryu S
Structural basis for calcium-stimulating pore formation of Vibrio α-hemolysin.
1. Nat Commun - published September 2, 2023
2. Chiu YC, Yeh MC, Wang CH, Chen YA, Chang H, Lin HY, Ho MC, Lin SM
Towards solving the mystery of peroxisomal matrix protein import.
1. Trends Cell Biol - published September 2, 2023
2. Skowyra ML, Feng P, Rapoport TA
How do land supply admittance regulations affect urban carbon emissions?
1. J Environ Manage - published September 2, 2023
2. Hu Y, He F, Liao K, Liu X
Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB.
1. mBio - published September 2, 2023
2. Childress KO, Cencer CS, Tyska MJ, Lacy DB
Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors.
1. PLoS Pathog - published September 2, 2023
2. Clark ND, Pham C, Kurniyati K, Sze CW, Coleman L, Fu Q, Zhang S, Malkowski MG, Li C
Host range, transmissibility and antigenicity of a pangolin coronavirus.
1. Nat Microbiol - published September 2, 2023
2. Hou YJ, Chiba S, Leist SR, Meganck RM, Martinez DR, Schäfer A, Catanzaro NJ, Sontake V, West A, Edwards CE, Yount B, Lee RE, Gallant SC, Zost SJ, Powers J, Adams L, Kong EF, Mattocks M, Tata A, Randell SH, Tata PR, Halfmann P, Crowe JE Jr, Kawaoka Y, Baric RS
Structural and functional insights into δ-poly-L-ornithine polymer biosynthesis from Acinetobacter baumannii.
1. Commun Biol - published September 2, 2023
2. Patel KD, Gulick AM
Local defocus estimation in Single Particle Analysis in Cryo-Electron Microscopy.
1. J Struct Biol - published September 2, 2023
2. Fernandez-Gimenez E, Carazo JM, Sorzano COS
A prospective randomized clinical trial to assess antibiotic pocket irrigation on tissue expander breast reconstruction.
1. Microbiol Spectr - published September 2, 2023
2. Walker JN, Hanson BM, Hunter T, Simar SR, Duran Ramirez JM, Obernuefemann CLP, Parikh RP, Tenenbaum MM, Margenthaler JA, Hultgren SJ, Myckatyn TM
Aptamer-thrombin loaded magnetic microspheres for bio-specific extraction and precise detection of hirudin.
1. Talanta - published September 2, 2023
2. Cao X, Luo Y, Liu X, Shang C, Lu J, Song G, Deng C
A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
1. Sci Transl Med - published September 2, 2023
2. Tse LV, Hou YJ, McFadden E, Lee RE, Scobey TD, Leist SR, Martinez DR, Meganck RM, Schäfer A, Yount BL, Mascenik T, Powers JM, Randell SH, Zhang Y, Wang L, Mascola J, McLellan JS, Baric RS
Identification of Matriglycan by Dual Exoglycosidase Digestion of α-Dystroglycan.
1. Bio Protoc - published September 2, 2023
2. Chandel I, Campbell KP
Neuraminidase-dependent entry of influenza A virus is determined by hemagglutinin receptor-binding specificity.
1. J Virol - published September 2, 2023
2. Wallace LE, de Vries E, van Kuppeveld FJM, de Haan CAM
Proteome census upon nutrient stress reveals Golgiphagy membrane receptors.
1. Nature - published September 2, 2023
2. Hickey KL, Swarup S, Smith IR, Paoli JC, Miguel Whelan E, Paulo JA, Harper JW
Acinetobacter type VI secretion system comprises a non-canonical membrane complex.
1. PLoS Pathog - published September 2, 2023
2. Kandolo O, Cherrak Y, Filella-Merce I, Le Guenno H, Kosta A, Espinosa L, Santucci P, Verthuy C, Lebrun R, Nilges M, Pellarin R, Durand E
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry.
1. J Am Chem Soc - published September 2, 2023
2. Sarott RC, You I, Li YD, Toenjes ST, Donovan KA, Seo P, Ordonez M, Byun WS, Hassan MM, Wachter F, Chouchani ET, Słabicki M, Fischer ES, Ebert BL, Hinshaw SM, Gray NS
Comparative analysis of the physical properties of murine and human S100A7: insight into why zinc piracy is mediated by human but not murine S100A7.
1. J Biol Chem - published September 2, 2023
2. Harrison SA, Naretto A, Balakrishnan S, Perera YR, Chazin WJ
Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction.
1. Cell Rep - published September 2, 2023
2. Adhikary U, Paulo JA, Godes M, Roychoudhury S, Prew MS, Ben-Nun Y, Yu EW, Budhraja A, Opferman JT, Chowdhury D, Gygi SP, Walensky LD
Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection.
1. Cell Host Microbe - published September 2, 2023
2. Spiga L, Fansler RT, Perera YR, Shealy NG, Munneke MJ, David HE, Torres TP, Lemoff A, Ran X, Richardson KL, Pudlo N, Martens EC, Folta-Stogniew E, Yang ZJ, Skaar EP, Byndloss MX, Chazin WJ, Zhu W
Disrupting Dimeric β-Amyloid by Electric Fields.
1. ACS Phys Chem Au - published September 2, 2023
2. Vargas-Rosales PA, D'Addio A, Zhang Y, Caflisch A
Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection.
1. bioRxiv - published September 2, 2023
2. Armbruster EG, Lee J, Hutchings J, VanderWal AR, Enustun E, Adler BA, Aindow A, Deep A, Rodriguez ZK, Morgan CJ, Ghassemian M, Charles E, Cress BF, Savage DF, Doudna JA, Pogliano K, Corbett KD, Villa E, Pogliano J
An amino acid-resolution interactome for motile cilia illuminates the structure and function of ciliopathy protein complexes.
1. bioRxiv - published September 2, 2023
2. McCafferty CL, Papoulas O, Lee C, Bui KH, Taylor DW, Marcotte EM, Wallingford JB
Discovering chromatin dysregulation induced by protein-coding perturbations at scale.
1. bioRxiv - published September 2, 2023
2. Frenkel M, Hujoel MLA, Morris Z, Raman S
Structure of RADX and mechanism for regulation of RAD51 nucleofilaments.
1. bioRxiv - published September 2, 2023
2. Balakrishnan S, Adolph M, Tsai MS, Gallagher K, Cortez D, Chazin WJ
A phage nucleus-associated RNA-binding protein is required for jumbo phage infection.
1. bioRxiv - published September 2, 2023
2. Enustun E, Armbruster EG, Lee J, Zhang S, Yee BA, Gu Y, Deep A, Naritomi JT, Liang Q, Aigner S, Adler BA, Cress BF, Doudna JA, Chaikeeratisak V, Cleveland DW, Ghassemian M, Yeo GW, Pogliano J, Corbett KD
Structural basis of transcription: RNA Polymerase II substrate binding and metal coordination at 3.0 Å using a free-electron laser.
1. bioRxiv - published September 2, 2023
2. Lin G, Barnes CO, Weiss S, Dutagaci B, Qiu C, Feig M, Song J, Lyubimov A, Cohen AE, Kaplan CD, Calero G
An integrative approach unveils a distal encounter site for rPTPε and phospho-Src complex formation.
1. Structure - published September 2, 2023
2. EswarKumar N, Yang CH, Tewary S, Peng WH, Chen GC, Yeh YQ, Yang HC, Ho MC
Proteomic Profiling in Patients With Peripartum Cardiomyopathy: A Biomarker Study of the ESC EORP PPCM Registry.
1. JACC Heart Fail - published September 2, 2023
2. Kodogo V, Viljoen C, Hoevelmann J, Chakafana G, Tromp J, Farhan HA, Goland S, van der Meer P, Karaye K, Kryczka K, Hilfiker-Kleiner D, Jackson A, Mebazaa A, Böhm M, Pieske B, Bauersachs J, Bell L, Sliwa K, EURObservational Research Programme in conjunction with the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy
Rapid screening and identification of superoxide dismutase activators from traditional Chinese medicines based on affinity ultrafiltration mass chromatography combined with molecular docking.
1. J Chromatogr A - published September 2, 2023
2. Guo Y, Gong P, Qian Y, Liu H, Yu B, Qi J
Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN Domain.
1. bioRxiv - published September 2, 2023
2. Small GI, Fedorova O, Olinares PDB, Chandanani J, Banerjee A, Choi YJ, Molina H, Chait B, Darst SA, Campbell EA
Activin E is a TGFβ ligand that signals specifically through activin receptor-like kinase 7.
1. bioRxiv - published September 2, 2023
2. Vestal KA, Kattamuri C, Koyiloth M, Ongaro L, Howard JA, Deaton A, Ticau S, Dubey A, Bernard DJ, Thompson TB
A Small Multidrug Resistance Transporter in Pseudomonas aeruginosa Confers Substrate-Specific Resistance or Susceptibility.
1. bioRxiv - published September 2, 2023
2. Wegrzynowicz AK, Heelan WJ, Demas SP, McLean MS, Peters JM, Henzler-Wildman KA
Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1.
1. bioRxiv - published September 2, 2023
2. Son Y, Kenny TC, Khan A, Birsoy K, Hite RK
Bacterial antiviral defense pathways encode eukaryotic-like ubiquitination systems.
1. bioRxiv - published September 2, 2023
2. Chambers LR, Ye Q, Cai J, Gong M, Ledvina HE, Zhou H, Whiteley AT, Suhandynata RT, Corbett KD
Glucocorticoid Receptor Activation in Lobular Breast Cancer Is Associated with Reduced Cell Proliferation and Promotion of Metastases.
1. Cancers (Basel) - published September 2, 2023
2. Porter BA, Frerich C, Lainé M, Clark AB, Durdana I, Lee J, Taya M, Sahoo S, Greene GL, Bennett L, Conzen SD
Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke.
1. Neural Regen Res - published September 1, 2023
2. Wang J, He P, Tian Q, Luo Y, He Y, Liu C, Gong P, Guo Y, Ye Q, Li M
A SAM-key domain required for enzymatic activity of the Fun30 nucleosome remodeler.
1. Life Sci Alliance - published September 1, 2023
2. Karl LA, Galanti L, Bantele SC, Metzner F, Šafarić B, Rajappa L, Foster B, Pires VB, Bansal P, Chacin E, Basquin J, Duderstadt KE, Kurat CF, Bartke T, Hopfner KP, Pfander B
Commentary on `Facing the phase problem' by Wayne Hendrickson.
1. IUCrJ - published September 1, 2023
2. Smith JL
LGP2 directly interacts with flavivirus NS5 RNA-dependent RNA polymerase and downregulates its pre-elongation activities.
1. PLoS Pathog - published September 1, 2023
2. Tan Z, Wu J, Huang L, Wang T, Zheng Z, Zhang J, Ke X, Zhang Y, Liu Y, Wang H, Tao J, Gong P
Proteomics-Based Discovery of First-in-Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2).
1. Angew Chem Int Ed Engl - published September 1, 2023
2. Ji W, Byun WS, Lu W, Zhu X, Donovan KA, Dwyer B, Che J, Yuan L, Abulaiti X, Corsello SM, Fischer ES, Zhang T, Gray NS
Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis.
1. J Biol Chem - published September 1, 2023
2. Thoden JB, McKnight JO, Kroft CW, Jast JDT, Holden HM
Phase separation promotes a highly active oligomeric scaffold of the MLL1 core complex for regulation of histone H3K4 methylation.
1. J Biol Chem - published September 1, 2023
2. Namitz KEW, Showalter SA, Cosgrove MS
Parallel molecular computation on digital data stored in DNA.
1. Proc Natl Acad Sci U S A - published September 1, 2023
2. Wang B, Wang SS, Chalk C, Ellington AD, Soloveichik D
RNase L-activating 2'-5' oligoadenylates bind ABCF1, ABCF3 and Decr-1.
1. J Gen Virol - published September 1, 2023
2. Govande AA, Babnis AW, Urban C, Habjan M, Hartmann R, Kranzusch PJ, Pichlmair A
Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs.
1. Nat Struct Mol Biol - published September 1, 2023
2. Swift ML, Zhou R, Syed A, Moreau LA, Tomasik B, Tainer JA, Konstantinopoulos PA, D'Andrea AD, He YJ, Chowdhury D
Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding.
1. Nat Commun - published September 1, 2023
2. Girodat D, Wieden HJ, Blanchard SC, Sanbonmatsu KY
A designer peptide against the EAG2-Kvβ2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma.
1. Nat Cancer - published September 1, 2023
2. Dong W, Fekete A, Chen X, Liu H, Beilhartz GL, Chen X, Bahrampour S, Xiong Y, Yang Q, Zhao H, Kong T, Morioka MS, Jung G, Kim JE, Schramek D, Dirks PB, Song Y, Kim TH, He Y, Wanggou S, Li X, Melnyk RA, Wang LY, Huang X
Rapid In Situ Thermal Decontamination of Wearable Composite Textile Materials.
1. ACS Appl Mater Interfaces - published September 1, 2023
2. Bell MD, Ye K, Yap TF, Rajappan A, Liu Z, Tao YJ, Preston DJ
Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry.
1. Biochemistry - published September 1, 2023
2. Pallan PS, Lybrand TP, Rozners E, Abramov M, Schepers G, Eremeeva E, Herdewijn P, Egli M
Architects of the membrane: structures of eukaryotic choline phosphotransferase 1 and choline/ethanolamine phosphotransferase 1.
1. Nat Struct Mol Biol - published September 1, 2023
2. Raina R, Banerjee A
Impact of a TLR9 agonist and broadly neutralizing antibodies on HIV-1 persistence: the randomized phase 2a TITAN trial.
1. Nat Med - published September 1, 2023
2. Gunst JD, Højen JF, Pahus MH, Rosás-Umbert M, Stiksrud B, McMahon JH, Denton PW, Nielsen H, Johansen IS, Benfield T, Leth S, Gerstoft J, Østergaard L, Schleimann MH, Olesen R, Støvring H, Vibholm L, Weis N, Dyrhol-Riise AM, Pedersen KBH, Lau JSY, Copertino DC Jr, Linden N, Huynh TT, Ramos V, Jones RB, Lewin SR, Tolstrup M, Rasmussen TA, Nussenzweig MC, Caskey M, Reikvam DH, Søgaard OS
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker.
1. Cancer Discov - published September 1, 2023
2. Taylor MS, Wu C, Fridy PC, Zhang SJ, Senussi Y, Wolters JC, Cajuso T, Cheng WC, Heaps JD, Miller BD, Mori K, Cohen L, Jiang H, Molloy KR, Chait BT, Goggins MG, Bhan I, Franses JW, Yang X, Taplin ME, Wang X, Christiani DC, Johnson BE, Meyerson M, Uppaluri R, Egloff AM, Denault EN, Spring LM, Wang TL, Shih IM, Fairman JE, Jung E, Arora KS, Yilmaz OH, Cohen S, Sharova T, Chi G, Norden BL, Song Y, Nieman LT, Pappas L, Parikh AR, Strickland MR, Corcoran RB, Mustelin T, Eng G, Yilmaz OH, Matulonis UA, Skates SJ, Rueda BR, Drapkin R, Klempner SJ, Deshpande V, Ting DT, Rout MP, LaCava J, Walt DR, Burns KH
A prospective multi-center observational study of surgical versus non-surgical management for pituitary apoplexy.
1. J Clin Endocrinol Metab - published September 1, 2023
2. Mamelak AN, Little AS, Gardner PA, Almeida JP, Recinos P, Soni P, Kshettry VR, Jane JA, Barkhoudarian G, Kelly DF, Dodd R, Mukherjee D, Gersey ZC, Fukuhara N, Nishioka H, Kim EH, Litré CF, Sina E, Mazer MW, Cui Y, Bonert V
A review of applied research on low-carbon urban design: based on scientific knowledge mapping.
1. Environ Sci Pollut Res Int - published September 1, 2023
2. Wang G, Wan Y, Ding CJ, Liu X, Jiang Y
Evolution of structural rearrangements in prostate cancer intracranial metastases.
1. NPJ Precis Oncol - published September 1, 2023
2. Khani F, Hooper WF, Wang X, Chu TR, Shah M, Winterkorn L, Sigouros M, Conteduca V, Pisapia D, Wobker S, Walker S, Graff JN, Robinson B, Mosquera JM, Sboner A, Elemento O, Robine N, Beltran H
A new algorithm for particle weighted subtraction to decrease signals from unwanted components in Single Particle Analysis.
1. J Struct Biol - published September 1, 2023
2. Fernández-Giménez E, Martínez MM, Marabini R, Strelak D, Sánchez-García R, Carazo JM, Sorzano COS
Structure challenges in the multivalency of Tau-microtubule interactions.
1. Cytoskeleton (Hoboken) - published September 1, 2023
2. Nogales E, Kellogg E
Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses.
1. Nat Commun - published September 1, 2023
2. Chapman NS, Hulswit RJG, Westover JLB, Stass R, Paesen GC, Binshtein E, Reidy JX, Engdahl TB, Handal LS, Flores A, Gowen BB, Bowden TA, Crowe JE Jr
Graphene Field Effect Biosensor for Concurrent and Specific Detection of SARS-CoV-2 and Influenza.
1. ACS Nano - published September 1, 2023
2. Kumar N, Towers D, Myers S, Galvin C, Kireev D, Ellington AD, Akinwande D
Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease.
1. NPJ Regen Med - published September 1, 2023
2. Ma C, Park MS, Alves do Monte F, Gokani V, Aruwajoye OO, Ren Y, Liu X, Kim HKW
Multivalent Dynamic Colocalization of Avian Influenza Polymerase and Nucleoprotein by Intrinsically Disordered ANP32A Reveals the Molecular Basis of Human Adaptation.
1. J Am Chem Soc - published September 1, 2023
2. Camacho-Zarco AR, Yu L, Krischuns T, Dedeoglu S, Maurin D, Bouvignies G, Crépin T, Ruigrok RWH, Cusack S, Naffakh N, Blackledge M
Nitrilium ion trapping as a strategy to access structurally diverse heterobiaryl-containing peptide macrocycles.
1. Chem Sci - published September 1, 2023
2. Diamandas M, Heller NW, Yudin AK
A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer.
1. PLoS Biol - published September 1, 2023
2. Hubert CG, Stauffer SR, Lathia JD
Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry.
1. Chem Sci - published September 1, 2023
2. Yin V, Devine PWA, Saunders JC, Barendregt A, Cusdin F, Ristani A, Hines A, Shepherd S, Dembek M, Dobson CL, Snijder J, Bond NJ, Heck AJR
Evolution of androgen receptors contributes to species variation in androgenic regulation of communication signals in electric fishes.
1. Mol Cell Endocrinol - published September 1, 2023
2. Proffitt MR, Liu X, Ortlund EA, Smith GT
Author Correction: An ATP-sensitive phosphoketolase regulates carbon fixation in cyanobacteria.
1. Nat Metab - published September 1, 2023
2. Lu KJ, Chang CW, Wang CH, Chen FY, Huang IY, Huang PH, Yang CH, Wu HY, Wu WJ, Hsu KC, Ho MC, Tsai MD, Liao JC
Reply to Record et al. "The role of PMP22 T118M in Charcot-Marie-Tooth disease remains unsolved".
1. J Biol Chem - published September 1, 2023
2. Stefanski KM, Li GC, Marinko JT, Carter BD, Samuels DC, Sanders CR
A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody.
1. Cell Rep - published September 1, 2023
2. Svoboda P, Haviernik J, Bednar P, Matkovic M, Cervantes Rincón T, Keeffe J, Palus M, Salat J, Agudelo M, Nussenzweig MC, Cavalli A, Robbiani DF, Ruzek D
GLUT3 promotes macrophage signaling and function via Ras-mediated endocytosis in atopic dermatitis and wound healing.
1. J Clin Invest - published September 1, 2023
2. Yu DM, Zhao J, Lee EE, Kim D, Mahapatra R, Rose EK, Zhou Z, Hosler CR, El-Kurdi A, Choe JY, Abel ED, Hoxhaj G, Westover KD, Cho RJ, Cheng JB, Wang RC
Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography.
1. Nat Chem - published September 1, 2023
2. Wolff AM, Nango E, Young ID, Brewster AS, Kubo M, Nomura T, Sugahara M, Owada S, Barad BA, Ito K, Bhowmick A, Carbajo S, Hino T, Holton JM, Im D, O'Riordan LJ, Tanaka T, Tanaka R, Sierra RG, Yumoto F, Tono K, Iwata S, Sauter NK, Fraser JS, Thompson MC
Function and phylogeny support the independent evolution of an ASIC-like Deg/ENaC channel in the Placozoa.
1. Commun Biol - published September 1, 2023
2. Elkhatib W, Yanez-Guerra LA, Mayorova TD, Currie MA, Singh A, Perera M, Gauberg J, Senatore A
Drug delivery systems for CRISPR-based genome editors.
1. Nat Rev Drug Discov - published September 1, 2023
2. Madigan V, Zhang F, Dahlman JE
Correlative montage parallel array cryo-tomography for in situ structural cell biology.
1. Nat Methods - published September 1, 2023
2. Yang JE, Larson MR, Sibert BS, Kim JY, Parrell D, Sanchez JC, Pappas V, Kumar A, Cai K, Thompson K, Wright ER
Unleashing the potential of CRISPR multiplexing: Harnessing Cas12 and Cas13 for precise gene modulation in eye diseases.
1. Vision Res - published September 1, 2023
2. Bigini F, Lee SH, Sun YJ, Sun Y, Mahajan VB
Robert Letsinger and the Evolution of Oligonucleotide Synthesis.
1. ACS Omega - published September 1, 2023
2. Egli M
RNA Repair: Hiding in Plain Sight.
1. Annu Rev Genet - published September 1, 2023
2. Shuman S
Interactions of human mitochondrial Ferredoxin 1 (Adrenodoxin) by NMR; modulation by cytochrome P450 substrate and by truncation of the C-terminal tail.
1. J Inorg Biochem - published September 1, 2023
2. Jay N, McGlohon JE, Estrada DF
Can Serum Chitotriosidase Levels, Immune and Oxidative Stress Parameters Be Early Diagnostic Indicators in Patients With Silicosis?
1. J Occup Environ Med - published September 1, 2023
2. Ergün R, Ergün D, Özkan E, Kar Kurt Ö, Bacanlı M, Körez MK
Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus.
1. PLoS Pathog - published September 1, 2023
2. Ou L, Chen SJ, Teng IT, Yang L, Zhang B, Zhou T, Biju A, Cheng C, Kong WP, Morano NC, Stancofski ED, Todd JP, Tsybovsky Y, Wang S, Zheng CY, Mascola JR, Shapiro L, Woodward RA, Buchholz UJ, Kwong PD
Biobanking of Human Aqueous and Vitreous Liquid Biopsies for Molecular Analyses.
1. J Vis Exp - published September 1, 2023
2. Wolf J, Chemudupati T, Kumar A, Rasmussen DK, Wai KM, Chang RT, Montague AA, Tang PH, Bassuk AG, Dufour A, Mruthrunjaya P, Mahajan VB