Member Publications

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106 Member Publications for November 2019

The Role of PAK1 in the Maturation of Invadopodia During Transient Mechanical Stimulation.
1. Front Cell Dev Biol - published November 30, 2019
2. Gasparski AN, Wilson JT, Banerjee A, Beningo KA
Metabolic Labeling of Inositol Phosphates and Phosphatidylinositols in Yeast and Mammalian Cells.
1. Methods Mol Biol - published November 28, 2019
2. Hale AT, Clarke BP, York JD
Reconstitution of the Human Nuclear RNA Exosome.
1. Methods Mol Biol - published November 27, 2019
2. Januszyk K, Weick EM, Lima CD
Reconstitution of S. cerevisiae RNA Exosome Complexes Using Recombinantly Expressed Proteins.
1. Methods Mol Biol - published November 27, 2019
2. Zinder JC, Lima CD
Reconstitution of the Schizosaccharomyces pombe RNA Exosome.
1. Methods Mol Biol - published November 27, 2019
2. Januszyk K, Lima CD
Strategies for Generating RNA Exosome Complexes from Recombinant Expression Hosts.
1. Methods Mol Biol - published November 27, 2019
2. Weick EM, Zinder JC, Lima CD
Concurrent activation of growth factor and nutrient arms of mTORC1 induces oxidative liver injury.
1. Cell Discov - published November 23, 2019
2. Cho CS, Kowalsky AH, Namkoong S, Park SR, Wu S, Kim B, James A, Gu B, Semple IA, Tohamy MA, Solanki S, Cho US, Greenson JK, Shah YM, Kim M, Lee JH
Virus-Receptor Interactions: Structural Insights For Oncolytic Virus Development.
1. Oncolytic Virother - published November 23, 2019
2. Jayawardena N, Burga LN, Poirier JT, Bostina M
Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
1. Cell Host Microbe - published November 13, 2019
2. Pinto D, Fenwick C, Caillat C, Silacci C, Guseva S, Dehez F, Chipot C, Barbieri S, Minola A, Jarrossay D, Tomaras GD, Shen X, Riva A, Tarkowski M, Schwartz O, Bruel T, Dufloo J, Seaman MS, Montefiori DC, Lanzavecchia A, Corti D, Pantaleo G, Weissenhorn W
Protein Dynamics in Phosphoryl-Transfer Signaling Mediated by Two-Component Systems.
1. Methods Mol Biol - published November 11, 2019
2. Trajtenberg F, Buschiazzo A
Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
1. Angew Chem Int Ed Engl - published November 8, 2019
2. Wheeler R, Yu X, Hou C, Mitra P, Chen JM, Herkules F, Ivanov DN, Tsodikov OV, Rohr J
A colorimetric detection of microRNA-148a in gastric cancer by gold nanoparticles-RNA conjugates.
1. Nanotechnology - published November 8, 2019
2. Cai J, Ding L, Gong P, Huang J
Structural Implications of STAT3 and STAT5 SH2 Domain Mutations.
1. Cancers (Basel) - published November 8, 2019
2. de Araujo ED, Orlova A, Neubauer HA, Bajusz D, Seo HS, Dhe-Paganon S, Keserű GM, Moriggl R, Gunning PT
Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules.
1. Dev Cell - published November 8, 2019
2. Zehr EA, Szyk A, Szczesna E, Roll-Mecak A
[Spatial Temporal Characteristics and Cluster Analysis of Chemical Components for Ambient PM_2.5 in Wuhan].
1. Huan Jing Ke Xue - published November 8, 2019
2. Zhang HT, Tian YZ, Liu BS, Yang JM, Yu J, Gong P, Wu JH, Zhang YF
Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts.
1. Sci Rep - published November 7, 2019
2. Ernst P, Honegger A, van der Valk F, Ewald C, Mittl PRE, Plückthun A
LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells.
1. Cell Mol Immunol - published November 7, 2019
2. Li Z, Deng M, Huang F, Jin C, Sun S, Chen H, Liu X, He L, Sadek AH, Zhang CC
Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
1. Structure - published November 7, 2019
2. Takizawa Y, Ho CH, Tachiwana H, Matsunami H, Kobayashi W, Suzuki M, Arimura Y, Hori T, Fukagawa T, Ohi MD, Wolf M, Kurumizaka H
Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance.
1. Mol Cell - published November 7, 2019
2. Iglesias N, Paulo JA, Tatarakis A, Wang X, Edwards AL, Bhanu NV, Garcia BA, Haas W, Gygi SP, Moazed D
Agonist Selectivity and Ion Permeation in the α3β4 Ganglionic Nicotinic Receptor.
1. Neuron - published November 6, 2019
2. Gharpure A, Teng J, Zhuang Y, Noviello CM, Walsh RM Jr, Cabuco R, Howard RJ, Zaveri NT, Lindahl E, Hibbs RE
Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine.
1. Org Biomol Chem - published November 6, 2019
2. Barzak FM, Harjes S, Kvach MV, Kurup HM, Jameson GB, Filichev VV, Harjes E
Molecular insight into a new low affinity xylan binding module from the xylanolytic gut symbiont Roseburia intestinalis.
1. FEBS J - published November 6, 2019
2. Leth ML, Ejby M, Madland E, Kitaoku Y, Slotboom DJ, Guskov A, Aachmann FL, Abou Hachem M
Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection.
1. Sci Transl Med - published November 6, 2019
2. Swale C, Bougdour A, Gnahoui-David A, Tottey J, Georgeault S, Laurent F, Palencia A, Hakimi MA
A Markerless Method for Genome Engineering in Zymomonas mobilis ZM4.
1. Front Microbiol - published November 5, 2019
2. Lal PB, Wells FM, Lyu Y, Ghosh IN, Landick R, Kiley PJ
Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling.
1. Sci Signal - published November 5, 2019
2. Jarrett SM, Seegar TCM, Andrews M, Adelmant G, Marto JA, Aster JC, Blacklow SC
Epigenetic modification of H3K4 and oxidative stress are involved in MC-LR-induced apoptosis in testicular cells of SD rats.
1. Environ Toxicol - published November 5, 2019
2. Yuan L, Liu H, Liu X, Zhang X, Wu J, Wang Y, Du X, Wang R, Ma Y, Chen X, Petlulu P, Cheng X, Zhuang D, Guo H, Zhang H
Pat1 activates late steps in mRNA decay by multiple mechanisms.
1. Proc Natl Acad Sci U S A - published November 5, 2019
2. Lobel JH, Tibble RW, Gross JD
An engineered antibody fragment targeting mutant β-catenin via Major Histocompatibility Complex I neoantigen presentation.
1. J Biol Chem - published November 5, 2019
2. Miller MS, Douglass J, Hwang MS, Skora AD, Murphy M, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S, Gabelli SB
Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer.
1. Antibodies (Basel) - published November 5, 2019
2. Harel ET, Drake PM, Barfield RM, Lui I, Farr-Jones S, Van't Veer L, Gartner ZJ, Green EM, Lourenço AL, Cheng Y, Hann BC, Rabuka D, Craik CS
Netrin Synergizes Signaling and Adhesion through DCC.
1. Trends Biochem Sci - published November 5, 2019
2. Meijers R, Smock RG, Zhang Y, Wang JH
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.
1. Nat Chem Biol - published November 4, 2019
2. Faust TB, Yoon H, Nowak RP, Donovan KA, Li Z, Cai Q, Eleuteri NA, Zhang T, Gray NS, Fischer ES
Computational Analysis of Energy Landscapes Reveals Dynamic Features That Contribute to Binding of Inhibitors to CFTR-Associated Ligand.
1. J Phys Chem B - published November 2, 2019
2. Holt GT, Jou JD, Gill NP, Lowegard AU, Martin JW, Madden DR, Donald BR
Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex.
1. Cell - published November 2, 2019
2. Shen K, Rogala KB, Chou HT, Huang RK, Yu Z, Sabatini DM
End-Binding E3 Ubiquitin Ligases Enable Protease Signaling.
1. ACS Chem Biol - published November 2, 2019
2. Ravalin M, Basu K, Gestwicki JE, Craik CS
Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1.
1. DNA Repair (Amst) - published November 2, 2019
2. Minko IG, Vartanian VL, Tozaki NN, Coskun E, Coskun SH, Jaruga P, Yeo J, David SS, Stone MP, Egli M, Dizdaroglu M, McCullough AK, Lloyd RS
Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from Leishmania major.
1. Biochemistry - published November 2, 2019
2. Feliciano PR, Drennan CL
In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls.
1. Nat Commun - published November 2, 2019
2. Jiang W, Birtley JR, Hung SC, Wang W, Chiou SH, Macaubas C, Kornum B, Tian L, Huang H, Adler L, Weaver G, Lu L, Ilstad-Minnihan A, Somasundaram S, Ayyangar S, Davis MM, Stern LJ, Mellins ED
Structural determinants of microtubule minus end preference in CAMSAP CKK domains.
1. Nat Commun - published November 2, 2019
2. Atherton J, Luo Y, Xiang S, Yang C, Rai A, Jiang K, Stangier M, Vemu A, Cook AD, Wang S, Roll-Mecak A, Steinmetz MO, Akhmanova A, Baldus M, Moores CA
The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling.
1. J Immunol - published November 2, 2019
2. Greenberg ZJ, Monlish DA, Bartnett RL, Yang Y, Shen G, Li W, Bednarski JJ, Schuettpelz LG
Author Correction: The choroid plexus is an important circadian clock component.
1. Nat Commun - published November 2, 2019
2. Myung J, Schmal C, Hong S, Tsukizawa Y, Rose P, Zhang Y, Holtzman MJ, De Schutter E, Herzel H, Bordyugov G, Takumi T
Dynamics of activating and repressive histone modifications in Drosophila neural stem cell lineages and brain tumors.
1. Development - published November 2, 2019
2. Abdusselamoglu MD, Landskron L, Bowman SK, Eroglu E, Burkard T, Kingston RE, Knoblich JA
Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology.
1. Elife - published November 2, 2019
2. Tao X, MacKinnon R
Kangaroo Mother Care implementation research to develop models for accelerating scale-up in India and Ethiopia: study protocol for an adequacy evaluation.
1. BMJ Open - published November 2, 2019
2. Medhanyie AA, Alemu H, Asefa A, Beyene SA, Gebregizabher FA, Aziz K, Bhandari N, Beyene H, Brune T, Chan G, Cranmer JN, Darmstadt G, Duguma D, Fikre A, Andualem BG, Gobezayehu AG, Mariam DH, Abay TH, Mohan HL, Jadaun A, Jayanna K, Kajal FNU, Kar A, Krishna R, Kumar A, Kumar V, Madhur TK, Belew ML, M R, Martines J, Mazumder S, Amin H, Mony PK, Muleta M, Pileggi-Castro C, Pn Rao S, Estifanos AS, Sibley LM, Singhal N, Tadele H, Tariku A, Lemango ET, Tadesse BT, Upadhyay R, Worku B, Hadush MY, Bahl R, KMC Scale-Up Study Group.
Poly(ADP-ribose) polymerase enzymes and the maintenance of genome integrity.
1. Cell Mol Life Sci - published November 2, 2019
2. Eisemann T, Pascal JM
Draft Genome Sequences of 40 Pathogenic Leptospira Strains Isolated from Cattle in Uruguay.
1. Microbiol Resour Announc - published November 2, 2019
2. Nieves C, Ferrés I, Díaz-Viraqué F, Buschiazzo A, Zarantonelli L, Iraola G
Computational design of a modular protein sense-response system.
1. Science - published November 2, 2019
2. Glasgow AA, Huang YM, Mandell DJ, Thompson M, Ritterson R, Loshbaugh AL, Pellegrino J, Krivacic C, Pache RA, Barlow KA, Ollikainen N, Jeon D, Kelly MJS, Fraser JS, Kortemme T
Breath Test Gas Patterns in Inflammatory Bowel Disease with Concomitant Irritable Bowel Syndrome-Like Symptoms: A Controlled Large-Scale Database Linkage Analysis.
1. Dig Dis Sci - published November 2, 2019
2. Gu P, Patel D, Lakhoo K, Ko J, Liu X, Chang B, Pan D, Lentz G, Sonesen M, Estiandan R, Lin E, Pimentel M, Rezaie A
Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
1. J Exp Med - published November 2, 2019
2. Zhao H, Xu L, Bombardi R, Nargi R, Deng Z, Errico JM, Nelson CA, Dowd KA, Pierson TC, Crowe JE Jr, Diamond MS, Fremont DH
CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.
1. PLoS Pathog - published November 2, 2019
2. Kamga L, Gil A, Song I, Brody R, Ghersi D, Aslan N, Stern LJ, Selin LK, Luzuriaga K
Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance.
1. Proc Natl Acad Sci U S A - published November 2, 2019
2. Thomas LR, Adams CM, Wang J, Weissmiller AM, Creighton J, Lorey SL, Liu Q, Fesik SW, Eischen CM, Tansey WP
Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.
1. J Biol Chem - published November 2, 2019
2. Han H, Schubert HL, McCullough J, Monroe N, Purdy MD, Yeager M, Sundquist WI, Hill CP
In situ structure determination at nanometer resolution using TYGRESS.
1. Nat Methods - published November 2, 2019
2. Song K, Shang Z, Fu X, Lou X, Grigorieff N, Nicastro D
High-throughput transposon sequencing highlights the cell wall as an important barrier for osmotic stress in methicillin resistant Staphylococcus aureus and underlines a tailored response to different osmotic stressors.
1. Mol Microbiol - published November 2, 2019
2. Schuster CF, Wiedemann DM, Kirsebom FCM, Santiago M, Walker S, Gründling A
Real time dynamics of gating-related conformational changes in CorA.
1. Elife - published November 2, 2019
2. Rangl M, Schmandt N, Perozo E, Scheuring S
Four New Iridoid Metabolites Have Been Isolated from the Stems of Neonauclea reticulata (Havil.) Merr. with Anti-Inflammatory Activities on LPS-Induced RAW264.7 Cells.
1. Molecules - published November 2, 2019
2. Chang FP, Huang SS, Lee TH, Chang CI, Kuo TF, Huang GJ, Kuo YH
The L-platform/L-scaffold framework: a blueprint for RNA-cleaving nucleic acid enzyme design.
1. RNA - published November 2, 2019
2. Gaines CS, Piccirilli JA, York DM
Integrative modelling of biomolecular complexes.
1. J Mol Biol - published November 2, 2019
2. Koukos PI, Bonvin AMJJ
Different mechanisms for translocation by monomeric and hexameric helicases.
1. Curr Opin Struct Biol - published November 2, 2019
2. Gao Y, Yang W
Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures.
1. Structure - published November 2, 2019
2. Berman HM, Adams PD, Bonvin AA, Burley SK, Carragher B, Chiu W, DiMaio F, Ferrin TE, Gabanyi MJ, Goddard TD, Griffin PR, Haas J, Hanke CA, Hoch JC, Hummer G, Kurisu G, Lawson CL, Leitner A, Markley JL, Meiler J, Montelione GT, Phillips GN Jr, Prisner T, Rappsilber J, Schriemer DC, Schwede T, Seidel CAM, Strutzenberg TS, Svergun DI, Tajkhorshid E, Trewhella J, Vallat B, Velankar S, Vuister GW, Webb B, Westbrook JD, White KL, Sali A
Automated sequence design of 2D wireframe DNA origami with honeycomb edges.
1. Nat Commun - published November 2, 2019
2. Jun H, Wang X, Bricker WP, Bathe M
Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis.
1. Structure - published November 2, 2019
2. Skiba MA, Tran CL, Dan Q, Sikkema AP, Klaver Z, Gerwick WH, Sherman DH, Smith JL
Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
1. Cell - published November 2, 2019
2. Lee CH, MacKinnon R
High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity.
1. Cell - published November 2, 2019
2. Setliff I, Shiakolas AR, Pilewski KA, Murji AA, Mapengo RE, Janowska K, Richardson S, Oosthuysen C, Raju N, Ronsard L, Kanekiyo M, Qin JS, Kramer KJ, Greenplate AR, McDonnell WJ, Graham BS, Connors M, Lingwood D, Acharya P, Morris L, Georgiev IS
Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
1. Mol Cell - published November 2, 2019
2. Zhang Y, Sun Y, Shi Y, Walz T, Tong L
Rethinking the Nitrogenase Mechanism: Activating the Active Site.
1. Joule - published November 2, 2019
2. Buscagan TM, Rees DC
Alcohol consumption increases susceptibility to pneumococcal pneumonia in a humanized murine HIV model mediated by intestinal dysbiosis.
1. Alcohol - published November 1, 2019
2. Samuelson DR, Siggins RW, Ruan S, Amedee AM, Sun J, Zhu QK, Marasco WA, Taylor CM, Luo M, Welsh DA, Shellito JE
PRODIGY-crystal: a web-tool for classification of biological interfaces in protein complexes.
1. Bioinformatics - published November 1, 2019
2. Jiménez-García B, Elez K, Koukos PI, Bonvin AM, Vangone A
Viral infections alter antennal epithelium ultrastructure in honey bees.
1. J Invertebr Pathol - published November 1, 2019
2. Kim SH, Mercer A, Mitchell A, de Miranda JR, Ward V, Mondet F, Bostina M
Validation of Human Sterol 14α-Demethylase (CYP51) Druggability: Structure-Guided Design, Synthesis, and Evaluation of Stoichiometric, Functionally Irreversible Inhibitors.
1. J Med Chem - published November 1, 2019
2. Friggeri L, Hargrove TY, Wawrzak Z, Guengerich FP, Lepesheva GI
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier.
1. Elife - published November 1, 2019
2. Brohawn SG, Wang W, Handler A, Campbell EB, Schwarz JR, MacKinnon R
Toward the computational design of protein crystals with improved resolution.
1. Acta Crystallogr D Struct Biol - published November 1, 2019
2. Jeliazkov JR, Robinson AC, García-Moreno E B, Berger JM, Gray JJ
Light on the cell cycle of the non-photosynthetic bacterium Ramlibacter tataouinensis.
1. Sci Rep - published November 1, 2019
2. De Luca G, Fochesato S, Lavergne J, Forest KT, Barakat M, Ortet P, Achouak W, Heulin T, Verméglio A
A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo.
1. Cancer Cell - published November 1, 2019
2. Bai L, Zhou H, Xu R, Zhao Y, Chinnaswamy K, McEachern D, Chen J, Yang CY, Liu Z, Wang M, Liu L, Jiang H, Wen B, Kumar P, Meagher JL, Sun D, Stuckey JA, Wang S
Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore.
1. Nat Microbiol - published November 1, 2019
2. Anderson DM, Sheedlo MJ, Jensen JL, Lacy DB
Cycles of autoubiquitination and deubiquitination regulate the ERAD ubiquitin ligase Hrd1.
1. Elife - published November 1, 2019
2. Peterson BG, Glaser ML, Rapoport TA, Baldridge RD
Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding.
1. Nucleic Acids Res - published November 1, 2019
2. Okafor IC, Singh D, Wang Y, Jung M, Wang H, Mallon J, Bailey S, Lee JK, Ha T
Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences.
1. Proc Natl Acad Sci U S A - published November 1, 2019
2. Meagher JL, Takata M, Gonçalves-Carneiro D, Keane SC, Rebendenne A, Ong H, Orr VK, MacDonald MR, Stuckey JA, Bieniasz PD, Smith JL
Coupling enhanced sampling of the apo-receptor with template-based ligand conformers selection: performance in pose prediction in the D3R Grand Challenge 4.
1. J Comput Aided Mol Des - published November 1, 2019
2. Basciu A, Koukos PI, Malloci G, Bonvin AMJJ, Vargiu AV
Can we use structural knowledge to design a protective vaccine against HIV-1?
1. HLA - published November 1, 2019
2. Bjorkman PJ
Structural biology of thermoTRPV channels.
1. Cell Calcium - published November 1, 2019
2. Yuan P
Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA.
1. Elife - published November 1, 2019
2. Lee J, Tomasek D, Santos T, May MD, Meuskens I, Kahne D
Quantifying secondary transport at single-molecule resolution.
1. Nature - published November 1, 2019
2. Fitzgerald GA, Terry DS, Warren AL, Quick M, Javitch JA, Blanchard SC
A non-canonical monovalent zinc finger stabilizes the integration of Cfp1 into the H3K4 methyltransferase complex COMPASS.
1. Nucleic Acids Res - published November 1, 2019
2. Yang Y, Joshi M, Takahashi YH, Ning Z, Qu Q, Brunzelle JS, Skiniotis G, Figeys D, Shilatifard A, Couture JF
Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer.
1. Nat Commun - published November 1, 2019
2. Zurlo G, Liu X, Takada M, Fan C, Simon JM, Ptacek TS, Rodriguez J, von Kriegsheim A, Liu J, Locasale JW, Robinson A, Zhang J, Holler JM, Kim B, Zikánová M, Bierau J, Xie L, Chen X, Li M, Perou CM, Zhang Q
Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site.
1. Nat Commun - published November 1, 2019
2. Rosen LE, Klebba JE, Asfaha JB, Ghent CM, Campbell MG, Cheng Y, Morgan DO
Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome.
1. Science - published November 1, 2019
2. Zhu PJ, Khatiwada S, Cui Y, Reineke LC, Dooling SW, Kim JJ, Li W, Walter P, Costa-Mattioli M
Multiple conformations facilitate PilT function in the type IV pilus.
1. Nat Commun - published November 1, 2019
2. McCallum M, Benlekbir S, Nguyen S, Tammam S, Rubinstein JL, Burrows LL, Howell PL
Effect of the Ionic Concentration of Simulated Body Fluid on the Minerals Formed on Cross-Linked Elastin-Like Polypeptide Membranes.
1. Langmuir - published November 1, 2019
2. Gourgas O, Cole GB, Muiznieks LD, Sharpe S, Cerruti M
Development and Characterization of a Wee1 Kinase Degrader.
1. Cell Chem Biol - published November 1, 2019
2. Li Z, Pinch BJ, Olson CM, Donovan KA, Nowak RP, Mills CE, Scott DA, Doctor ZM, Eleuteri NA, Chung M, Sorger PK, Fischer ES, Gray NS
Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus.
1. PLoS Pathog - published November 1, 2019
2. Coe KA, Lee W, Stone MC, Komazin-Meredith G, Meredith TC, Grad YH, Walker S
Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core.
1. Biochemistry - published November 1, 2019
2. Biok NA, Passow AD, Wang C, Bingman CA, Abbott NL, Gellman SH
Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex.
1. Nat Struct Mol Biol - published November 1, 2019
2. Nguyen AH, Thomsen ARB, Cahill TJ 3rd, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Little J 4th, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ
Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
1. Proc Natl Acad Sci U S A - published November 1, 2019
2. Jia N, Unciuleac MC, Xue C, Greene EC, Patel DJ, Shuman S
A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity.
1. Elife - published November 1, 2019
2. Palmer AC, Chidley C, Sorger PK
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions.
1. Sci Rep - published November 1, 2019
2. Tóth G, Neumann T, Berthet A, Masliah E, Spencer B, Tao J, Jobling MF, Gardai SJ, Bertoncini CW, Cremades N, Bova M, Ballaron S, Chen XH, Mao W, Nguyen P, Tabios MC, Tambe MA, Rochet JC, Junker HD, Schwizer D, Sekul R, Ott I, Anderson JP, Szoke B, Hoffman W, Christodoulou J, Yednock T, Agard DA, Schenk D, McConlogue L
Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
1. J Gen Physiol - published November 1, 2019
2. Zangerl-Plessl EM, Lee SJ, Maksaev G, Bernsteiner H, Ren F, Yuan P, Stary-Weinzinger A, Nichols CG
A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
1. MBio - published November 1, 2019
2. Cheng Z, Shurina BA, Bethel CR, Thomas PW, Marshall SH, Thomas CA, Yang K, Kimble RL, Montgomery JS, Orischak MG, Miller CM, Tennenbaum JL, Nix JC, Tierney DL, Fast W, Bonomo RA, Page RC, Crowder MW
Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors.
1. ACS Med Chem Lett - published November 1, 2019
2. De Clercq DJH, Heppner DE, To C, Jang J, Park E, Yun CH, Mushajiang M, Shin BH, Gero TW, Scott DA, Jänne PA, Eck MJ, Gray NS
Recent insights into the structure of TFIID, its assembly, and its binding to core promoter.
1. Curr Opin Struct Biol - published November 1, 2019
2. Patel AB, Greber BJ, Nogales E
Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice.
1. Cell Host Microbe - published November 1, 2019
2. Gilchuk IM, Bangaru S, Gilchuk P, Irving RP, Kose N, Bombardi RG, Thornburg NJ, Creech CB, Edwards KM, Li S, Turner HL, Yu W, Zhu X, Wilson IA, Ward AB, Crowe JE Jr
Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling.
1. Cell - published November 1, 2019
2. Valencia AM, Collings CK, Dao HT, St Pierre R, Cheng YC, Huang J, Sun ZY, Seo HS, Mashtalir N, Comstock DE, Bolonduro O, Vangos NE, Yeoh ZC, Dornon MK, Hermawan C, Barrett L, Dhe-Paganon S, Woolf CJ, Muir TW, Kadoch C
A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice.
1. J Vis Exp - published November 1, 2019
2. Zhang J, Fang F, Li L, Huang H, Webber HC, Sun Y, Mahajan VB, Hu Y
Allosteric modulation of nucleoporin assemblies by intrinsically disordered regions.
1. Sci Adv - published November 1, 2019
2. Blus BJ, Koh J, Krolak A, Seo HS, Coutavas E, Blobel G
Liquid-like and rigid-body motions in molecular-dynamics simulations of a crystalline protein.
1. Struct Dyn - published November 1, 2019
2. Wych DC, Fraser JS, Mobley DL, Wall ME
Extracellular matrix micropatterning technology for whole cell cryogenic electron microscopy studies.
1. J Micromech Microeng - published November 1, 2019
2. Engel L, Gaietta G, Dow LP, Swift MF, Pardon G, Volkmann N, Weis WI, Hanein D, Pruitt BL
Characterization of the genomically encoded fosfomycin resistance enzyme from Mycobacterium abscessus.
1. Medchemcomm - published November 1, 2019
2. Travis S, Shay MR, Manabe S, Gilbert NC, Frantom PA, Thompson MK