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114 Member Publications for December 2018

Molecular and epigenetic regulatory mechanisms of normal stem cell radiosensitivity.
1. Cell Death Discov - published December 28, 2018
2. Fabbrizi MR, Warshowsky KE, Zobel CL, Hallahan DE, Sharma GG
Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.
1. Nat Commun - published December 21, 2018
2. Vasiliauskaité-Brooks I, Healey RD, Rochaix P, Saint-Paul J, Sounier R, Grison C, Waltrich-Augusto T, Fortier M, Hoh F, Saied EM, Arenz C, Basu S, Leyrat C, Granier S
Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth.
1. PLoS One - published December 20, 2018
2. Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE Jr
Structural insights into DDA1 function as a core component of the CRL4-DDB1 ubiquitin ligase.
1. Cell Discov - published December 20, 2018
2. Shabek N, Ruble J, Waston CJ, Garbutt KC, Hinds TR, Li T, Zheng N
Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs.
1. PLoS One - published December 19, 2018
2. Holt ME, Salay LE, O'Brien E, Barton JK, Chazin WJ
The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
1. Biochemistry - published December 18, 2018
2. Starbird CA, Perry NA, Chen Q, Berndt S, Yamakawa I, Loukachevitch LV, Limbrick EM, Bachmann BO, Iverson TM, McCulloch KM
Spindle Checkpoint Regulators in Insulin Signaling.
1. Front Cell Dev Biol - published December 18, 2018
2. Choi E, Yu H
Key role of the REC lobe during CRISPR-Cas9 activation by 'sensing', 'regulating', and 'locking' the catalytic HNH domain.
1. Q Rev Biophys - published December 18, 2018
2. Palermo G, Chen JS, Ricci CG, Rivalta I, Jinek M, Batista VS, Doudna JA, McCammon JA
Refining the Quality of Monoclonal Antibodies: Grafting Unique Peptide-Binding Site in the Fab Framework.
1. Methods Mol Biol - published December 13, 2018
2. King JD, Williams JC
BCL-2 Protein Family Interaction Analysis by Nuclear Magnetic Resonance Spectroscopy.
1. Methods Mol Biol - published December 12, 2018
2. Garner TP, Gavathiotis E
Liposomal Permeabilization Assay to Study the Functional Interactions of the BCL-2 Family.
1. Methods Mol Biol - published December 12, 2018
2. Reyna DE, Gavathiotis E
The C terminus of the bacterial multidrug transporter EmrE couples drug binding to proton release.
1. J Biol Chem - published December 7, 2018
2. Thomas NE, Wu C, Morrison EA, Robinson AE, Werner JP, Henzler-Wildman KA
A Membrane Protein Complex Docking Benchmark.
1. J Mol Biol - published December 7, 2018
2. Koukos PI, Faro I, van Noort CW, Bonvin AMJJ
Host-targeted niclosamide inhibits C. difficile virulence and prevents disease in mice without disrupting the gut microbiota.
1. Nat Commun - published December 7, 2018
2. Tam J, Hamza T, Ma B, Chen K, Beilhartz GL, Ravel J, Feng H, Melnyk RA
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.
1. J Med Chem - published December 7, 2018
2. Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC
Hyaluronic Acid Grafted Nanoparticles of a Platinum(II)-Silicon(IV) Phthalocyanine Conjugate for Tumor and Mitochondria-Targeted Photodynamic Therapy in Red Light.
1. J Mater Chem B - published December 7, 2018
2. Mitra K, Samso M, Lyons CE, Hartman MCT
Elucidating the Catalytic Power of Glutamate Racemase by Investigating a Series of Covalent Inhibitors.
1. ChemMedChem - published December 6, 2018
2. Vance NR, Witkin KR, Rooney PW, Li Y, Pope M, Spies MA
Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation.
1. Mol Cell - published December 6, 2018
2. Garcia-Saez I, Menoni H, Boopathi R, Shukla MS, Soueidan L, Noirclerc-Savoye M, Le Roy A, Skoufias DA, Bednar J, Hamiche A, Angelov D, Petosa C, Dimitrov S
A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure.
1. Elife - published December 6, 2018
2. Pollak AJ, Liu C, Gudlur A, Mayfield JE, Dalton ND, Gu Y, Chen J, Heller Brown J, Hogan PG, Wiley SE, Peterson KL, Dixon JE
Recognition of the Diglycine C-End Degron by CRL2KLHDC2 Ubiquitin Ligase.
1. Mol Cell - published December 6, 2018
2. Rusnac DV, Lin HC, Canzani D, Tien KX, Hinds TR, Tsue AF, Bush MF, Yen HS, Zheng N
Fenestrations control resting-state block of a voltage-gated sodium channel.
1. Proc Natl Acad Sci U S A - published December 5, 2018
2. Gamal El-Din TM, Lenaeus MJ, Zheng N, Catterall WA
Structural Basis of TRPV4 N Terminus Interaction with Syndapin/PACSIN1-3 and PIP2.
1. Structure - published December 4, 2018
2. Goretzki B, Glogowski NA, Diehl E, Duchardt-Ferner E, Hacker C, Gaudet R, Hellmich UA
Structural Basis for tRNA Mimicry by a Bacterial Y RNA.
1. Structure - published December 4, 2018
2. Wang W, Chen X, Wolin SL, Xiong Y
Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse.
1. Wellcome Open Res - published December 4, 2018
2. Beilin C, Choudhuri K, Bouma G, Malinova D, Llodra J, Stokes DL, Shimaoka M, Springer TA, Dustin ML, Thrasher AJ, Burns SO
Review of Ocular Manifestations of Joubert Syndrome.
1. Genes (Basel) - published December 4, 2018
2. Wang SF, Kowal TJ, Ning K, Koo EB, Wu AY, Mahajan VB, Sun Y
Cryo-electron microscopy structure of the lipid droplet-formation protein seipin.
1. J Cell Biol - published December 3, 2018
2. Sui X, Arlt H, Brock KP, Lai ZW, DiMaio F, Marks DS, Liao M, Farese RV Jr, Walther TC
Microtubule-severing enzymes: From cellular functions to molecular mechanism.
1. J Cell Biol - published December 3, 2018
2. McNally FJ, Roll-Mecak A
The weak voltage dependence of pannexin 1 channels can be tuned by N-terminal modifications.
1. J Gen Physiol - published December 3, 2018
2. Michalski K, Henze E, Nguyen P, Lynch P, Kawate T
Decapping enzymes STOP "cancer" ribosomes in their tracks.
1. EMBO J - published December 3, 2018
2. Mugridge JS, Gross JD
A strategy to identify a ketoreductase that preferentially synthesizes pharmaceutically relevant (S)-alcohols using whole-cell biotransformation.
1. Microb Cell Fact - published December 3, 2018
2. Haq SF, Shanbhag AP, Karthikeyan S, Hassan I, Thanukrishnan K, Ashok A, Sukumaran S, Ramaswamy S, Bharatham N, Datta S, Samant S, Katagihallimath N
Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
1. J Gen Physiol - published December 3, 2018
2. Gamal El-Din TM, Lenaeus MJ, Ramanadane K, Zheng N, Catterall WA
Structure and activity of lipid bilayer within a membrane-protein transporter.
1. Proc Natl Acad Sci U S A - published December 3, 2018
2. Qiu W, Fu Z, Xu GG, Grassucci RA, Zhang Y, Frank J, Hendrickson WA, Guo Y
A Steric Gating Mechanism Dictates the Substrate Specificity of a Rab-GEF.
1. Dev Cell - published December 3, 2018
2. Thomas LL, van der Vegt SA, Fromme JC
YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria.
1. J Biol Chem - published December 2, 2018
2. Ohlemacher SI, Xu Y, Kober DL, Malik M, Nix JC, Brett TJ, Henderson JP
Structural and Functional Studies of a gem-Dimethylating Methyltransferase from a trans-Acyltransferase Assembly Line.
1. ACS Chem Biol - published December 2, 2018
2. Meinke JL, Mehaffey MR, Wagner DT, Sun N, Zhang Z, Brodbelt JS, Keatinge-Clay AT
Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
1. Science - published December 2, 2018
2. Patel AB, Louder RK, Greber BJ, Grünberg S, Luo J, Fang J, Liu Y, Ranish J, Hahn S, Nogales E
Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta.
1. ACS Chem Biol - published December 2, 2018
2. Moss NA, Leão T, Rankin MR, McCullough TM, Qu P, Korobeynikov A, Smith JL, Gerwick L, Gerwick WH
qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps.
1. J Med Chem - published December 2, 2018
2. van Zundert GCP, Hudson BM, de Oliveira SHP, Keedy DA, Fonseca R, Heliou A, Suresh P, Borrelli K, Day T, Fraser JS, van den Bedem H
Structural Basis of Polyketide Synthase O-Methylation.
1. ACS Chem Biol - published December 2, 2018
2. Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL
Crystal structure of Bacillus thuringiensis Cry7Cal toxin active against Locusta migratoria manilensis.
1. Protein Sci - published December 2, 2018
2. Jing X, Yuan Y, Wu Y, Wu D, Gong P, Gao M
Molecular basis for the acid-initiated uncoating of human enterovirus D68.
1. Proc Natl Acad Sci U S A - published December 2, 2018
2. Liu Y, Sheng J, van Vliet ALW, Buda G, van Kuppeveld FJM, Rossmann MG
Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
1. Proc Natl Acad Sci U S A - published December 2, 2018
2. Zhang K, Shang G, Padavannil A, Wang J, Sakthivel R, Chen X, Kim M, Thompson MG, García-Sastre A, Lynch KW, Chen ZJ, Chook YM, Fontoura BMA
Crystal structure of the human NK₁ tachykinin receptor.
1. Proc Natl Acad Sci U S A - published December 2, 2018
2. Yin J, Chapman K, Clark LD, Shao Z, Borek D, Xu Q, Wang J, Rosenbaum DM
Yeast require redox switching in DNA primase.
1. Proc Natl Acad Sci U S A - published December 2, 2018
2. O'Brien E, Salay LE, Epum EA, Friedman KL, Chazin WJ, Barton JK
A BAF'ling Approach to Curing HIV.
1. Cell Chem Biol - published December 2, 2018
2. Tomar S, Ali I, Ott M
A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA.
1. Nat Commun - published December 2, 2018
2. Yates LA, Aramayo RJ, Pokhrel N, Caldwell CC, Kaplan JA, Perera RL, Spies M, Antony E, Zhang X
USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors.
1. Mol Cell - published December 2, 2018
2. Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Sambel LA, Ponnienselvan K, Liu JC, Yang C, Kozono D, Parmar K, Yusufzai T, Zheng N, D'Andrea AD
A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement.
1. Elife - published December 2, 2018
2. Wang X, Piersma SJ, Christopher NA, Dia YN, Christensen T, Lazear E, Yang L, Sluijter M, van Hall T, Hansen TH, Yokoyama WM, Fremont DH
HLA-DO modulates the diversity of the MHC-II self-peptidome.
1. Mol Cell Proteomics - published December 2, 2018
2. Nanaware PP, Jurewicz MM, Leszyk J, Shaffer SA, Stern LJ
Publisher Correction: Structural and molecular mechanisms for the control of eukaryotic 5'-3' mRNA decay.
1. Nat Struct Mol Biol - published December 2, 2018
2. Mugridge JS, Coller J, Gross JD
Quantitative iTRAQ-based proteomic analysis of piperine protected cerebral ischemia/reperfusion injury in rat brain.
1. Neurochem Int - published December 2, 2018
2. Zou Y, Gong P, Zhao W, Zhang J, Wu X, Xin C, Xiong Z, Li Z, Wu X, Wan Q, Li X, Chen J
Mechanisms of opening and closing of the bacterial replicative helicase.
1. Elife - published December 2, 2018
2. Chase J, Catalano A, Noble AJ, Eng ET, Olinares PD, Molloy K, Pakotiprapha D, Samuels M, Chait B, des Georges A, Jeruzalmi D
The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1.
1. Elife - published December 2, 2018
2. Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P
LiaR-Independent Pathways to Daptomycin Resistance in Enterococcus faecalis Reveal A Multilayer Defense Against Cell Envelope Antibiotics.
1. Mol Microbiol - published December 2, 2018
2. Miller WR, Tran TT, Diaz L, Rios R, Khan A, Reyes J, Prater AG, Panesso D, Shamoo Y, Arias CA
Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors.
1. Proc Natl Acad Sci U S A - published December 2, 2018
2. Li C, Bonazzoli E, Bellone S, Choi J, Dong W, Menderes G, Altwerger G, Han C, Manzano A, Bianchi A, Pettinella F, Manara P, Lopez S, Yadav G, Riccio F, Zammataro L, Zeybek B, Yang-Hartwich Y, Buza N, Hui P, Wong S, Ravaggi A, Bignotti E, Romani C, Todeschini P, Zanotti L, Zizioli V, Odicino F, Pecorelli S, Ardighieri L, Silasi DA, Litkouhi B, Ratner E, Azodi M, Huang GS, Schwartz PE, Lifton RP, Schlessinger J, Santin AD
Current Understanding of Humoral Immunity to Enterovirus D68.
1. J Pediatric Infect Dis Soc - published December 2, 2018
2. Vogt MR, Crowe JE Jr
Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels.
1. J Gen Physiol - published December 2, 2018
2. Finol-Urdaneta RK, McArthur JR, Goldschen-Ohm MP, Gaudet R, Tikhonov DB, Zhorov BS, French RJ
β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility.
1. Skelet Muscle - published December 2, 2018
2. Kim J, Grotegut CA, Wisler JW, Li T, Mao L, Chen M, Chen W, Rosenberg PB, Rockman HA, Lefkowitz RJ
Collection of Continuous Rotation MicroED Data from Ion Beam-Milled Crystals of Any Size.
1. Structure - published December 2, 2018
2. Martynowycz MW, Zhao W, Hattne J, Jensen GJ, Gonen T
Evaluation and selection of anatomic sites for magnetic resonance imaging-guided mild hyperthermia therapy: a healthy volunteer study.
1. Int J Hyperthermia - published December 1, 2018
2. V V N Kothapalli S, Altman MB, Zhu L, Partanen A, Cheng G, Gach HM, Straube W, Zoberi I, Hallahan DE, Chen H
CYP51 as drug targets for fungi and protozoan parasites: past, present and future.
1. Parasitology - published December 1, 2018
2. Lepesheva GI, Friggeri L, Waterman MR
Gram-negative synthase-dependent exopolysaccharide biosynthetic machines.
1. Curr Opin Struct Biol - published December 1, 2018
2. Low KE, Howell PL
An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice.
1. Gastroenterology - published December 1, 2018
2. Edderkaoui M, Chheda C, Soufi B, Zayou F, Hu RW, Ramanujan VK, Pan X, Boros LG, Tajbakhsh J, Madhav A, Bhowmick NA, Wang Q, Lewis M, Tuli R, Habtezion A, Murali R, Pandol SJ
Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses.
1. Gastroenterology - published December 1, 2018
2. Alvarado G, Ettayebi K, Atmar RL, Bombardi RG, Kose N, Estes MK, Crowe JE Jr
Potent Neutralizing Human Monoclonal Antibodies Preferentially Target Mature Dengue Virus Particles: Implication for Novel Strategy for Dengue Vaccine.
1. J Virol - published December 1, 2018
2. Tsai WY, Chen HL, Tsai JJ, Dejnirattisai W, Jumnainsong A, Mongkolsapaya J, Screaton G, Crowe JE Jr, Wang WK
A structural view of the initiators for chromosome replication.
1. Curr Opin Struct Biol - published December 1, 2018
2. On KF, Jaremko M, Stillman B, Joshua-Tor L
Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli.
1. Nat Microbiol - published December 1, 2018
2. Omattage NS, Deng Z, Pinkner JS, Dodson KW, Almqvist F, Yuan P, Hultgren SJ
Crystal structure of a biliverdin-bound phycobiliprotein: Interdependence of oligomerization and chromophorylation.
1. J Struct Biol - published December 1, 2018
2. Fuenzalida-Werner JP, Janowski R, Mishra K, Weidenfeld I, Niessing D, Ntziachristos V, Stiel AC
Characterization and development of SAPP as a specific peptidic inhibitor that targets Porphyromonas gingivalis.
1. Mol Oral Microbiol - published December 1, 2018
2. Ho MH, Lamont RJ, Chazin WJ, Chen H, Young DF, Kumar P, Xie H
acI Actinobacteria Assemble a Functional Actinorhodopsin with Natively Synthesized Retinal.
1. Appl Environ Microbiol - published December 1, 2018
2. Dwulit-Smith JR, Hamilton JJ, Stevenson DM, He S, Oyserman BO, Moya-Flores F, Garcia SL, Amador-Noguez D, McMahon KD, Forest KT
Small molecules that target group II introns are potent antifungal agents.
1. Nat Chem Biol - published December 1, 2018
2. Fedorova O, Jagdmann GE Jr, Adams RL, Yuan L, Van Zandt MC, Pyle AM
Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51.
1. J Biol Chem - published December 1, 2018
2. Hargrove TY, Wawrzak Z, Fisher PM, Child SA, Nes WD, Guengerich FP, Waterman MR, Lepesheva GI
Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs.
1. Nucleic Acids Res - published December 1, 2018
2. Nishimura T, Fakim H, Brandmann T, Youn JY, Gingras AC, Jinek M, Fabian MR
The Golgi 'casein kinase' Fam20C is a genuine 'phosvitin kinase' and phosphorylates polyserine stretches devoid of the canonical consensus.
1. FEBS J - published December 1, 2018
2. Cozza G, Moro E, Black M, Marin O, Salvi M, Venerando A, Tagliabracci VS, Pinna LA
Substrate Binding Regulates Redox Signaling in Human DNA Primase.
1. J Am Chem Soc - published December 1, 2018
2. O'Brien E, Holt ME, Salay LE, Chazin WJ, Barton JK
Sterol 14α-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae.
1. J Med Chem - published December 1, 2018
2. Friggeri L, Hargrove TY, Rachakonda G, Blobaum AL, Fisher P, de Oliveira GM, da Silva CF, Soeiro MNC, Nes WD, Lindsley CW, Villalta F, Guengerich FP, Lepesheva GI
High-resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist.
1. Nat Struct Mol Biol - published December 1, 2018
2. Ehrenmann J, Schöppe J, Klenk C, Rappas M, Kummer L, Doré AS, Plückthun A
Molecular structure of the ATP-bound, phosphorylated human CFTR.
1. Proc Natl Acad Sci U S A - published December 1, 2018
2. Zhang Z, Liu F, Chen J
Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins.
1. Neuron - published December 1, 2018
2. Cosmanescu F, Katsamba PS, Sergeeva AP, Ahlsen G, Patel SD, Brewer JJ, Tan L, Xu S, Xiao Q, Nagarkar-Jaiswal S, Nern A, Bellen HJ, Zipursky SL, Honig B, Shapiro L
Interactions between the Ig-Superfamily Proteins DIP-α and Dpr6/10 Regulate Assembly of Neural Circuits.
1. Neuron - published December 1, 2018
2. Xu S, Xiao Q, Cosmanescu F, Sergeeva AP, Yoo J, Lin Y, Katsamba PS, Ahlsen G, Kaufman J, Linaval NT, Lee PT, Bellen HJ, Shapiro L, Honig B, Tan L, Zipursky SL
Greasing the Wheels of Lipid Biology with Chemical Tools.
1. Trends Biochem Sci - published December 1, 2018
2. Bumpus TW, Baskin JM
Come, sweet death: targeting glycosomal protein import for antitrypanosomal drug development.
1. Curr Opin Microbiol - published December 1, 2018
2. Kalel VC, Mäser P, Sattler M, Erdmann R, Popowicz GM
PARP family enzymes: regulation and catalysis of the poly(ADP-ribose) posttranslational modification.
1. Curr Opin Struct Biol - published December 1, 2018
2. Langelier MF, Eisemann T, Riccio AA, Pascal JM
Thomas Steitz 1940-2018.
1. Nat Struct Mol Biol - published December 1, 2018
2. Ban N
Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance.
1. Proc Natl Acad Sci U S A - published December 1, 2018
2. Wang Y, Cho C, Williams J, Smallwood PM, Zhang C, Junge HJ, Nathans J
Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor.
1. Proc Natl Acad Sci U S A - published December 1, 2018
2. Zhao R, Kennedy K, De Blas GA, Orta G, Pavarotti MA, Arias RJ, de la Vega-Beltrán JL, Li Q, Dai H, Perozo E, Mayorga LS, Darszon A, Goldstein SAN
ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.
1. Nat Med - published December 1, 2018
2. Rotinen M, You S, Yang J, Coetzee SG, Reis-Sobreiro M, Huang WC, Huang F, Pan X, Yáñez A, Hazelett DJ, Chu CY, Steadman K, Morrissey CM, Nelson PS, Corey E, Chung LWK, Freedland SJ, Di Vizio D, Garraway IP, Murali R, Knudsen BS, Freeman MR
Atypical Hepatic Mesenchymal Hamartoma: Histologic Appearance, Immunophenotype, and Molecular Findings.
1. Pediatr Dev Pathol - published December 1, 2018
2. El Demellawy D, Lee JY, McDonell L, Dyment DA, Knisely AS, McGowan-Jordan J, Ngan B, Finegold M, Kapur RP, Nasr A
PseudoGTPase domains in p190RhoGAP proteins: a mini-review.
1. Biochem Soc Trans - published December 1, 2018
2. Stiegler AL, Boggon TJ
Structural and molecular mechanisms for the control of eukaryotic 5'-3' mRNA decay.
1. Nat Struct Mol Biol - published December 1, 2018
2. Mugridge JS, Coller J, Gross JD
Malleable folding of coiled-coils regulates kinesin-3 dimerization.
1. Proc Natl Acad Sci U S A - published December 1, 2018
2. Al-Bassam J, Nithianantham S
Molecular basis of signaling specificity between GIRK channels and GPCRs.
1. Elife - published December 1, 2018
2. Touhara KK, MacKinnon R
Publisher Correction: Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
1. Sci Rep - published December 1, 2018
2. Kirchdoerfer RN, Wang N, Pallesen J, Wrapp D, Turner HL, Cottrell CA, Corbett KS, Graham BS, McLellan JS, Ward AB
A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15.
1. Biophys J - published December 1, 2018
2. De-la-Torre P, Choudhary D, Araya-Secchi R, Narui Y, Sotomayor M
Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells.
1. EMBO J - published December 1, 2018
2. Mariappan A, Soni K, Schorpp K, Zhao F, Minakar A, Zheng X, Mandad S, Macheleidt I, Ramani A, Kubelka T, Dawidowski M, Golfmann K, Wason A, Yang C, Simons J, Schmalz HG, Hyman AA, Aneja R, Ullrich R, Urlaub H, Odenthal M, Büttner R, Li H, Sattler M, Hadian K, Gopalakrishnan J
Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner.
1. PLoS Pathog - published December 1, 2018
2. O'Brien VP, Dorsey DA, Hannan TJ, Hultgren SJ
Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.
1. Cell - published December 1, 2018
2. Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, Haas P, Schmidt CB, Schlesinger LS, LaCount DJ, Davey RA, Amarasinghe GK, Basler CF, Krogan NJ
Bruton's Tyrosine Kinase degradation as a therapeutic strategy for cancer.
1. Blood - published December 1, 2018
2. Dobrovolsky D, Wang ES, Morrow S, Leahy C, Faust T, Nowak RP, Donovan KA, Yang G, Li Z, Fischer ES, Treon SP, Weinstock DM, Gray NS
Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells.
1. Sci Immunol - published December 1, 2018
2. Benveniste PM, Roy S, Nakatsugawa M, Chen ELY, Nguyen L, Millar DG, Ohashi PS, Hirano N, Adams EJ, Zúñiga-Pflücker JC
Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.
1. Immunity - published December 1, 2018
2. Bonsignori M, Scott E, Wiehe K, Easterhoff D, Alam SM, Hwang KK, Cooper M, Xia SM, Zhang R, Montefiori DC, Henderson R, Nie X, Kelsoe G, Moody MA, Chen X, Joyce MG, Kwong PD, Connors M, Mascola JR, McGuire AT, Stamatatos L, Medina-Ramírez M, Sanders RW, Saunders KO, Kepler TB, Haynes BF
Tissue Plasminogen Activator Causes Brain Microvascular Endothelial Cell Injury After Oxygen Glucose Deprivation by Inhibiting Sonic Hedgehog Signaling.
1. Neurochem Res - published December 1, 2018
2. Gong P, Li M, Zou C, Tian Q, Xu Z
Editorial overview: Catalysis and regulation: Structural features guiding enzyme catalysed processes.
1. Curr Opin Struct Biol - published December 1, 2018
2. Vrielink A, Holden HM
Development of a novel, sensitive cell-based Corin Assay.
1. Biochem Pharmacol - published December 1, 2018
2. Lambertz P, Theisen L, Längst N, Garvie CW, MacDonald BT, Yu J, Elowe NH, Zubov D, Kaushik VK, Wunder F
HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA.
1. Cell - published December 1, 2018
2. Mohni KN, Wessel SR, Zhao R, Wojciechowski AC, Luzwick JW, Layden H, Eichman BF, Thompson PS, Mehta KPM, Cortez D
NMR for Biological Systems.
1. Chemphyschem - published December 1, 2018
2. Schanda P, Chekmenev EY
Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria.
1. J Am Chem Soc - published December 1, 2018
2. Orman M, Bodea S, Funk MA, Campo AM, Bollenbach M, Drennan CL, Balskus EP
Shed EBA-175 mediates red blood cell clustering that enhances malaria parasite growth and enables immune evasion.
1. Elife - published December 1, 2018
2. Paing MM, Salinas ND, Adams Y, Oksman A, Jensen AT, Goldberg DE, Tolia NH
Bio-Inspired Micropatterned Platforms Recapitulate 3D Physiological Morphologies of Bone and Dentinal Cells.
1. Adv Sci (Weinh) - published December 1, 2018
2. Ma C, Chang B, Jing Y, Kim H, Liu X
Deacetylated microbial biofilm exopolysaccharides: It pays to be positive.
1. PLoS Pathog - published December 1, 2018
2. Ostapska H, Howell PL, Sheppard DC
Accurate calculation of side chain packing and free energy with applications to protein molecular dynamics.
1. PLoS Comput Biol - published December 1, 2018
2. Jumper JM, Faruk NF, Freed KF, Sosnick TR
Temperature-Responsive Competitive Inhibition of CRISPR-Cas9.
1. Mol Cell - published December 1, 2018
2. Jiang F, Liu JJ, Osuna BA, Xu M, Berry JD, Rauch BJ, Nogales E, Bondy-Denomy J, Doudna JA
Nucleotide Spin Labeling for ESR Spectroscopy of ATP-Binding Proteins.
1. Appl Magn Reson - published December 1, 2018
2. Muok AR, Chua TK, Le H, Crane BR
A double-edged sword? Sub-types of psychological flexibility are associated with distinct psychiatric disorders.
1. J Res Pers - published December 1, 2018
2. C A D, N S C, W J C, M S, M R, M B
QSAR Studies of New Pyrido[3,4-b]indole Derivatives as Inhibitors of Colon and Pancreatic Cancer Cell Proliferation.
1. Med Chem Res - published December 1, 2018
2. Deokar H, Deokar M, Wang W, Zhang R, Buolamwini JK