Member Publications

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123 Member Publications for February 2017

Structural Insight into African Swine Fever Virus A179L-Mediated Inhibition of Apoptosis.
1. J Virol - published February 28, 2017
2. Banjara S, Caria S, Dixon LK, Hinds MG, Kvansakul M
Information-Driven, Ensemble Flexible Peptide Docking Using HADDOCK.
1. Methods Mol Biol - published February 26, 2017
2. Geng C, Narasimhan S, Rodrigues JP, Bonvin AM
Forkhead followed by disordered tail: The intrinsically disordered regions of FOXO3a.
1. Intrinsically Disord Proteins - published February 25, 2017
2. Wang F, Marshall CB, Ikura M
Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action.
1. J Proteome Res - published February 9, 2017
2. Norris JL, Farrow MA, Gutierrez DB, Palmer LD, Muszynski N, Sherrod SD, Pino JC, Allen JL, Spraggins JM, Lubbock AL, Jordan A, Burns W, Poland JC, Romer C, Manier ML, Nei YW, Prentice BM, Rose KL, Hill S, Van de Plas R, Tsui T, Braman NM, Keller MR, Rutherford SA, Lobdell N, Lopez CF, Lacy DB, McLean JA, Wikswo JP, Skaar EP, Caprioli RM
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing.
1. Nature - published February 9, 2017
2. Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT
A Sensitive in Vitro High-Throughput Screen To Identify Pan-filoviral Replication Inhibitors Targeting the VP35-NP Interface.
1. ACS Infect Dis - published February 9, 2017
2. Liu G, Nash PJ, Johnson B, Pietzsch C, Ilagan MX, Bukreyev A, Basler CF, Bowlin TL, Moir DT, Leung DW, Amarasinghe GK
Engineering potent long-acting variants of the Wnt inhibitor DKK2.
1. Protein Eng Des Sel - published February 9, 2017
2. Sopko R, Mugford JW, Lehmann A, Shapiro RI, Rushe M, Kulkarni A, Worrall J, Amatucci J, Wen D, Pederson NE, Minesinger BK, Arndt JW, Pepinsky B
Antibiotic-Induced Depletion of Anti-Inflammatory Clostridia is Associated with the Development of GVHD in Pediatric Stem Cell Transplant Patients.
1. Biol Blood Marrow Transplant - published February 9, 2017
2. Simms-Waldrip TR, Sunkersett G, Coughlin LA, Savani MR, Arana C, Kim J, Kim M, Zhan X, Greenberg DE, Xie Y, Davies SM, Koh AY
LRRC8A-dependent volume regulated anion channel activity is dispensable for T cell development and function.
1. J Allergy Clin Immunol - published February 9, 2017
2. Platt CD, Chou J, Houlihan P, Badran YR, Kumar L, Bainter W, Poliani PL, Perez CJ, Dent SY, Clapham DE, Benavides F, Geha RS
A role for muscarinic receptors in neutrophil extracellular trap formation and levamisole-induced autoimmunity.
1. JCI Insight - published February 9, 2017
2. Carmona-Rivera C, Purmalek MM, Moore E, Waldman M, Walter PJ, Garraffo HM, Phillips KA, Preston KL, Graf J, Kaplan MJ, Grayson PC
Arthropod Innate Immune Systems and Vector-Borne Diseases.
1. Biochemistry - published February 8, 2017
2. Baxter RH, Contet A, Krueger K
Evolution of Acid-Sensing Olfactory Circuits in Drosophilids.
1. Neuron - published February 8, 2017
2. Prieto-Godino LL, Rytz R, Cruchet S, Bargeton B, Abuin L, Silbering AF, Ruta V, Dal Peraro M, Benton R
Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal.
1. Elife - published February 8, 2017
2. Fuller JR, Rice PA
Mechanistic Insights into Neurotransmitter Release and Presynaptic Plasticity from the Crystal Structure of Munc13-1 C1C2BMUN.
1. Elife - published February 8, 2017
2. Xu J, Camacho M, Xu Y, Esser V, Liu X, Trimbuch T, Pan YZ, Ma C, Tomchick DR, Rosenmund C, Rizo J
N,N Dimethylacetamide a drug excipient that acts as bromodomain ligand for osteoporosis treatment.
1. Sci Rep - published February 8, 2017
2. Ghayor C, Gjoksi B, Dong J, Siegenthaler B, Caflisch A, Weber FE
Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis.
1. EMBO J - published February 8, 2017
2. Malyutin AG, Musalgaonkar S, Patchett S, Frank J, Johnson AW
When COI barcodes deceive: complete genomes reveal introgression in hairstreaks.
1. Proc Biol Sci - published February 8, 2017
2. Cong Q, Shen J, Borek D, Robbins RK, Opler PA, Otwinowski Z, Grishin NV
A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion.
1. J Virol - published February 8, 2017
2. Patel SJ, Zhao G, Penna VR, Park E, Lauron EJ, Harvey IB, Beatty WL, Plougastel-Douglas B, Poursine-Laurent J, Fremont DH, Wang D, Yokoyama WM
Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
1. Structure - published February 7, 2017
2. Nan R, Furze CM, Wright DW, Gor J, Wallis R, Perkins SJ
Complete genome of Pieris rapae, a resilient alien, a cabbage pest, and a source of anti-cancer proteins.
1. F1000Res - published February 7, 2017
2. Shen J, Cong Q, Kinch LN, Borek D, Otwinowski Z, Grishin NV
Movement of the β-hairpin in the third zinc-binding module of UvrA is required for DNA damage recognition.
1. DNA Repair (Amst) - published February 7, 2017
2. Kraithong T, Channgam K, Itsathitphaisarn O, Tiensuwan M, Jeruzalmi D, Pakotiprapha D
Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography.
1. Nat Microbiol - published February 6, 2017
2. Chang YW, Kjær A, Ortega DR, Kovacikova G, Sutherland JA, Rettberg LA, Taylor RK, Jensen GJ
In vitro reconstitution demonstrates the cell wall ligase activity of LCP proteins.
1. Nat Chem Biol - published February 6, 2017
2. Schaefer K, Matano LM, Qiao Y, Kahne D, Walker S
NMR insights into the conformational properties of Man-9 and its recognition by two HIV binding proteins.
1. Chembiochem - published February 6, 2017
2. Shahzad-Ul-Hussan S, Sastry M, Lemmin T, Soto C, Loesgen S, Scott DA, Davison JR, O'Connor R, Kwong PD, Bewley CA
Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes.
1. PLoS Pathog - published February 6, 2017
2. Groppelli E, Levy HC, Sun E, Strauss M, Nicol C, Gold S, Zhuang X, Tuthill TJ, Hogle JM, Rowlands DJ
Anti-trypanosomal activity of sterol 14α-demethylase (CYP51) inhibitors VNI and VFV in the Swiss mouse models of Chagas disease induced by the Y strain Trypanosoma cruzi.
1. Antimicrob Agents Chemother - published February 6, 2017
2. Guedes-da-Silva FH, Batista DG, Da Silva CF, De Araújo JS, Pavão BP, Simões-Silva MR, Meuser MB, Demarque KC, Moreira OC, Britto C, Lepesheva GI, Soeiro MN
Structural and Preclinical Studies of Computationally-Designed Non-nucleoside Reverse Transcriptase Inhibitors for Treating HIV infection.
1. Mol Pharmacol - published February 6, 2017
2. Kudalkar SN, Beloor J, Chan AH, Lee WG, Jorgensen WL, Kumar P, Anderson KS
A Structural View of αB-crystallin Assembly and Amyloid Aggregation.
1. Protein Pept Lett - published February 6, 2017
2. Liu Z, Zhang S, Li D, Liu C
PRODIGY: A Contact-based Predictor of Binding Affinity in Protein-protein Complexes.
1. Bio Protoc - published February 5, 2017
2. Vangone A, Bonvin AMJJ
The ins and outs of cyclic di-GMP signaling in Vibrio cholerae.
1. Curr Opin Microbiol - published February 4, 2017
2. Conner JG, Zamorano-Sánchez D, Park JH, Sondermann H, Yildiz FH
Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer.
1. PLoS One - published February 3, 2017
2. Takeda T, Yamamoto H, Kanzaki H, Suzawa K, Yoshioka T, Tomida S, Cui X, Murali R, Namba K, Sato H, Torigoe H, Watanabe M, Shien K, Soh J, Asano H, Tsukuda K, Kitamura Y, Miyoshi S, Sendo T, Toyooka S
Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens.
1. PLoS One - published February 3, 2017
2. Grondin JM, Duan D, Kirlin AC, Abe KT, Chitayat S, Spencer HL, Spencer C, Campigotto A, Houliston S, Arrowsmith CH, Allingham JS, Boraston AB, Smith SP
What Are the Most Powerful Immunogen Design Vaccine Strategies? A Structural Biologist's Perspective.
1. Cold Spring Harb Perspect Biol - published February 3, 2017
2. Kwong PD
Vitamin B12 in the spotlight again.
1. Curr Opin Chem Biol - published February 3, 2017
2. Bridwell-Rabb J, Drennan CL
OneDep: Unified wwPDB System for Deposition, Biocuration, and Validation of Macromolecular Structures in the PDB Archive.
1. Structure - published February 3, 2017
2. Young JY, Westbrook JD, Feng Z, Sala R, Peisach E, Oldfield TJ, Sen S, Gutmanas A, Armstrong DR, Berrisford JM, Chen L, Chen M, Di Costanzo L, Dimitropoulos D, Gao G, Ghosh S, Gore S, Guranovic V, Hendrickx PM, Hudson BP, Igarashi R, Ikegawa Y, Kobayashi N, Lawson CL, Liang Y, Mading S, Mak L, Mir MS, Mukhopadhyay A, Patwardhan A, Persikova I, Rinaldi L, Sanz-Garcia E, Sekharan MR, Shao C, Swaminathan GJ, Tan L, Ulrich EL, van Ginkel G, Yamashita R, Yang H, Zhuravleva MA, Quesada M, Kleywegt GJ, Berman HM, Markley JL, Nakamura H, Velankar S, Burley SK
Extraction of Thermodynamic Parameters of Protein Unfolding Using Parallelized Differential Scanning Fluorimetry.
1. J Phys Chem Lett - published February 2, 2017
2. Wright TA, Stewart JM, Page RC, Konkolewicz D
Intramembrane Proteolysis of Astrotactins.
1. J Biol Chem - published February 2, 2017
2. Chang H, Smallwood PM, Williams J, Nathans J
Targeting IRE1 with small molecules counteracts progression of atherosclerosis.
1. Proc Natl Acad Sci U S A - published February 2, 2017
2. Tufanli O, Telkoparan Akillilar P, Acosta-Alvear D, Kocaturk B, Onat UI, Hamid SM, Çimen I, Walter P, Weber C, Erbay E
Molecular basis for protection of ribosomal protein L4 from cellular degradation.
1. Nat Commun - published February 2, 2017
2. Huber FM, Hoelz A
Antigenic characterization of the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor incorporated into nanodiscs.
1. PLoS One - published February 2, 2017
2. Witt KC, Castillo-Menendez L, Ding H, Espy N, Zhang S, Kappes JC, Sodroski J
Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation.
1. Mol Cell - published February 2, 2017
2. Kundu S, Ji F, Sunwoo H, Jain G, Lee JT, Sadreyev RI, Dekker J, Kingston RE
Picornaviral Polymerase Structure, Function, and Fidelity Modulation.
1. Virus Res - published February 2, 2017
2. Peersen OB
Opportunities and Challenges in RNA Structural Modeling and Design.
1. Biophys J - published February 2, 2017
2. Schlick T, Pyle AM
Determination of glycoside hydrolase specificities during hydrolysis of plant cell walls using glycome profiling.
1. Biotechnol Biofuels - published February 2, 2017
2. Walker JA, Pattathil S, Bergeman LF, Beebe ET, Deng K, Mirzai M, Northen TR, Hahn MG, Fox BG
Aspartate Glycosylation Triggers Isomerization to Isoaspartate.
1. J Am Chem Soc - published February 2, 2017
2. Janetzko J, Walker S
Molecular determinants for CRISPR RNA maturation in the Cas10-Csm complex and roles for non-Cas nucleases.
1. Nucleic Acids Res - published February 2, 2017
2. Walker FC, Chou-Zheng L, Dunkle JA, Hatoum-Aslan A
Conformationally Preorganized Diastereomeric Norbornane-Based Maltosides for Membrane Protein Study: Implications of Detergent Kink for Micellar Properties.
1. J Am Chem Soc - published February 2, 2017
2. Das M, Du Y, Ribeiro O, Hariharan P, Mortensen JS, Patra D, Skiniotis G, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS
Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.
1. Nat Struct Mol Biol - published February 2, 2017
2. Liu Q, Acharya P, Dolan MA, Zhang P, Guzzo C, Lu J, Kwon A, Gururani D, Miao H, Bylund T, Chuang GY, Druz A, Zhou T, Rice WJ, Wigge C, Carragher B, Potter CS, Kwong PD, Lusso P
Releasing the cohesin ring: A rigid scaffold model for opening the DNA exit gate by Pds5 and Wapl.
1. Bioessays - published February 2, 2017
2. Ouyang Z, Yu H
New CRISPR-Cas systems discovered.
1. Cell Res - published February 2, 2017
2. Yang H, Patel DJ
Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis.
1. Proc Natl Acad Sci U S A - published February 2, 2017
2. Cahill TJ 3rd, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J 4th, Antar A, Blanc A, Qu CX, Chen X, Kawakami K, Inoue A, Aoki J, Steyaert J, Sun JP, Bouvier M, Skiniotis G, Lefkowitz RJ
Biomolecular condensates: organizers of cellular biochemistry.
1. Nat Rev Mol Cell Biol - published February 2, 2017
2. Banani SF, Lee HO, Hyman AA, Rosen MK
P. falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion.
1. Elife - published February 2, 2017
2. Sisquella X, Nebl T, Thompson JK, Whitehead L, Malpede BM, Salinas ND, Rogers K, Tolia NH, Fleig A, O'Neill J, Tham WH, Horgen FD, Cowman AF
Reconstitution of the tubular endoplasmic reticulum network with purified components.
1. Nature - published February 2, 2017
2. Powers RE, Wang S, Liu TY, Rapoport TA
Cryo-EM structure of the replisome reveals multiple interactions coordinating DNA synthesis.
1. Proc Natl Acad Sci U S A - published February 2, 2017
2. Kulczyk AW, Moeller A, Meyer P, Sliz P, Richardson CC
Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer.
1. Proc Natl Acad Sci U S A - published February 2, 2017
2. Adhikary S, Deredge DJ, Nagarajan A, Forrest LR, Wintrode PL, Singh SK
Crystal structure of Aquifex aeolicus σN bound to promoter DNA and the structure of σN-holoenzyme.
1. Proc Natl Acad Sci U S A - published February 2, 2017
2. Campbell EA, Kamath S, Rajashankar KR, Wu M, Darst SA
CatSperζ regulates the structural continuity of sperm Ca2+ signaling domains and is required for normal fertility.
1. Elife - published February 2, 2017
2. Chung JJ, Miki K, Kim D, Shim SH, Shi HF, Hwang JY, Cai X, Iseri Y, Zhuang X, Clapham DE
Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis.
1. PLoS One - published February 2, 2017
2. Ipsaro JJ, Shen C, Arai E, Xu Y, Kinney JB, Joshua-Tor L, Vakoc CR, Shi J
Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1.
1. Elife - published February 2, 2017
2. Rashid F, Harris PD, Zaher MS, Sobhy MA, Joudeh LI, Yan C, Piwonski H, Tsutakawa SE, Ivanov I, Tainer JA, Habuchi S, Hamdan SM
SnapShot: Class 1 CRISPR-Cas Systems.
1. Cell - published February 2, 2017
2. Makarova KS, Zhang F, Koonin EV
Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.
1. PLoS Pathog - published February 2, 2017
2. Easterhoff D, Moody MA, Fera D, Cheng H, Ackerman M, Wiehe K, Saunders KO, Pollara J, Vandergrift N, Parks R, Kim J, Michael NL, O'Connell RJ, Excler JL, Robb ML, Vasan S, Rerks-Ngarm S, Kaewkungwal J, Pitisuttithum P, Nitayaphan S, Sinangil F, Tartaglia J, Phogat S, Kepler TB, Alam SM, Liao HX, Ferrari G, Seaman MS, Montefiori DC, Tomaras GD, Harrison SC, Haynes BF
The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
1. Science - published February 2, 2017
2. O'Brien E, Holt ME, Thompson MK, Salay LE, Ehlinger AC, Chazin WJ, Barton JK
Epitopes and Mechanism of Action of the Clostridium Difficile Toxin A-Neutralizing Antibody Actoxumab.
1. J Mol Biol - published February 2, 2017
2. Hernandez LD, Kroh HK, Hsieh E, Yang X, Beaumont M, Sheth PR, DiNunzio E, Rutherford SA, Ohi MD, Ermakov G, Xiao L, Secore S, Karczewski J, Racine F, Mayhood T, Fischer P, Sher X, Gupta P, Lacy DB, Therien AG
Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism.
1. Chem Rev - published February 2, 2017
2. Cappadocia L, Lima CD
Performance of Emergency Department Screening Criteria for an Early ECG to Identify ST-Segment Elevation Myocardial Infarction.
1. J Am Heart Assoc - published February 2, 2017
2. Yiadom MY, Baugh CW, McWade CM, Liu X, Song KJ, Patterson BW, Jenkins CA, Tanski M, Mills AM, Salazar G, Wang TJ, Dittus RS, Liu D, Storrow AB
A Cell-free Method for Expressing and Reconstituting Membrane Proteins Enables Functional Characterization of the Plant Receptor-like Protein Kinase FERONIA.
1. J Biol Chem - published February 2, 2017
2. Minkoff BB, Makino SI, Haruta M, Beebe ET, Wrobel RL, Fox BG, Sussman MR
Structure of a pentameric virion-associated fiber with a potential role in Orsay virus entry to host cells.
1. PLoS Pathog - published February 2, 2017
2. Fan Y, Guo YR, Yuan W, Zhou Y, Holt MV, Wang T, Demeler B, Young NL, Zhong W, Tao YJ
Structural Basis of Substrate Recognition by the Multidrug Resistance Protein MRP1.
1. Cell - published February 2, 2017
2. Johnson ZL, Chen J
Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).
1. Clin Transl Allergy - published February 2, 2017
2. Bousquet J, Farrell J, Crooks G, Hellings P, Bel EH, Bewick M, Chavannes NH, de Sousa JC, Cruz AA, Haahtela T, Joos G, Khaltaev N, Malva J, Muraro A, Nogues M, Palkonen S, Pedersen S, Robalo-Cordeiro C, Samolinski B, Strandberg T, Valiulis A, Yorgancioglu A, Zuberbier T, Bedbrook A, Aberer W, Adachi M, Agusti A, Akdis CA, Akdis M, Ankri J, Alonso A, Annesi-Maesano I, Ansotegui IJ, Anto JM, Arnavielhe S, Arshad H, Bai C, Baiardini I, Bachert C, Baigenzhin AK, Barbara C, Bateman ED, Beghé B, Kheder AB, Bennoor KS, Benson M, Bergmann KC, Bieber T, Bindslev-Jensen C, Bjermer L, Blain H, Blasi F, Boner AL, Bonini M, Bonini S, Bosnic-Anticevitch S, Boulet LP, Bourret R, Bousquet PJ, Braido F, Briggs AH, Brightling CE, Brozek J, Buhl R, Burney PG, Bush A, Caballero-Fonseca F, Caimmi D, Calderon MA, Calverley PM, Camargos PA, Canonica GW, Camuzat T, Carlsen KH, Carr W, Carriazo A, Casale T, Cepeda Sarabia AM, Chatzi L, Chen YZ, Chiron R, Chkhartishvili E, Chuchalin AG, Chung KF, Ciprandi G, Cirule I, Cox L, Costa DJ, Custovic A, Dahl R, Dahlen SE, Darsow U, De Carlo G, De Blay F, Dedeu T, Deleanu D, De Manuel Keenoy E, Demoly P, Denburg JA, Devillier P, Didier A, Dinh-Xuan AT, Djukanovic R, Dokic D, Douagui H, Dray G, Dubakiene R, Durham SR, Dykewicz MS, El-Gamal Y, Emuzyte R, Fabbri LM, Fletcher M, Fiocchi A, Fink Wagner A, Fonseca J, Fokkens WJ, Forastiere F, Frith P, Gaga M, Gamkrelidze A, Garces J, Garcia-Aymerich J, Gemicioğlu B, Gereda JE, González Diaz S, Gotua M, Grisle I, Grouse L, Gutter Z, Guzmán MA, Heaney LG, Hellquist-Dahl B, Henderson D, Hendry A, Heinrich J, Heve D, Horak F, Hourihane JO, Howarth P, Humbert M, Hyland ME, Illario M, Ivancevich JC, Jardim JR, Jares EJ, Jeandel C, Jenkins C, Johnston SL, Jonquet O, Julge K, Jung KS, Just J, Kaidashev I, Khaitov MR, Kalayci O, Kalyoncu AF, Keil T, Keith PK, Klimek L, Koffi N'Goran B, Kolek V, Koppelman GH, Kowalski ML, Kull I, Kuna P, Kvedariene V, Lambrecht B, Lau S, Larenas-Linnemann D, Laune D, Le LT, Lieberman P, Lipworth B, Li J, Lodrup Carlsen K, Louis R, MacNee W, Magard Y, Magnan A, Mahboub B, Mair A, Majer I, Makela MJ, Manning P, Mara S, Marshall GD, Masjedi MR, Matignon P, Maurer M, Mavale-Manuel S, Melén E, Melo-Gomes E, Meltzer EO, Menzies-Gow A, Merk H, Michel JP, Miculinic N, Mihaltan F, Milenkovic B, Mohammad GM, Molimard M, Momas I, Montilla-Santana A, Morais-Almeida M, Morgan M, Mösges R, Mullol J, Nafti S, Namazova-Baranova L, Naclerio R, Neou A, Neffen H, Nekam K, Niggemann B, Ninot G, Nyembue TD, O'Hehir RE, Ohta K, Okamoto Y, Okubo K, Ouedraogo S, Paggiaro P, Pali-Schöll I, Panzner P, Papadopoulos N, Papi A, Park HS, Passalacqua G, Pavord I, Pawankar R, Pengelly R, Pfaar O, Picard R, Pigearias B, Pin I, Plavec D, Poethig D, Pohl W, Popov TA, Portejoie F, Potter P, Postma D, Price D, Rabe KF, Raciborski F, Radier Pontal F, Repka-Ramirez S, Reitamo S, Rennard S, Rodenas F, Roberts J, Roca J, Rodriguez Mañas L, Rolland C, Roman Rodriguez M, Romano A, Rosado-Pinto J, Rosario N, Rosenwasser L, Rottem M, Ryan D, Sanchez-Borges M, Scadding GK, Schunemann HJ, Serrano E, Schmid-Grendelmeier P, Schulz H, Sheikh A, Shields M, Siafakas N, Sibille Y, Similowski T, Simons FE, Sisul JC, Skrindo I, Smit HA, Solé D, Sooronbaev T, Spranger O, Stelmach R, Sterk PJ, Sunyer J, Thijs C, To T, Todo-Bom A, Triggiani M, Valenta R, Valero AL, Valia E, Valovirta E, Van Ganse E, van Hage M, Vandenplas O, Vasankari T, Vellas B, Vestbo J, Vezzani G, Vichyanond P, Viegi G, Vogelmeier C, Vontetsianos T, Wagenmann M, Wallaert B, Walker S, Wang DY, Wahn U, Wickman M, Williams DM, Williams S, Wright J, Yawn BP, Yiallouros PK, Yusuf OM, Zaidi A, Zar HJ, Zernotti ME, Zhang L, Zhong N, Zidarn M, Mercier J
1H, 13C and 15N backbone chemical shift assignments of camelid single-domain antibodies against active state µ-opioid receptor.
1. Biomol NMR Assign - published February 2, 2017
2. Sounier R, Yang Y, Hagelberger J, Granier S, Déméné H
A Partial Calcium-Free Linker Confers Flexibility to Inner-Ear Protocadherin-15.
1. Structure - published February 2, 2017
2. Powers RE, Gaudet R, Sotomayor M
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
1. JAMA Oncol - published February 2, 2017
2. Telomeres Mendelian Randomization Collaboration., Haycock PC, Burgess S, Nounu A, Zheng J, Okoli GN, Bowden J, Wade KH, Timpson NJ, Evans DM, Willeit P, Aviv A, Gaunt TR, Hemani G, Mangino M, Ellis HP, Kurian KM, Pooley KA, Eeles RA, Lee JE, Fang S, Chen WV, Law MH, Bowdler LM, Iles MM, Yang Q, Worrall BB, Markus HS, Hung RJ, Amos CI, Spurdle AB, Thompson DJ, O'Mara TA, Wolpin B, Amundadottir L, Stolzenberg-Solomon R, Trichopoulou A, Onland-Moret NC, Lund E, Duell EJ, Canzian F, Severi G, Overvad K, Gunter MJ, Tumino R, Svenson U, van Rij A, Baas AF, Bown MJ, Samani NJ, van t'Hof FN, Tromp G, Jones GT, Kuivaniemi H, Elmore JR, Johansson M, Mckay J, Scelo G, Carreras-Torres R, Gaborieau V, Brennan P, Bracci PM, Neale RE, Olson SH, Gallinger S, Li D, Petersen GM, Risch HA, Klein AP, Han J, Abnet CC, Freedman ND, Taylor PR, Maris JM, Aben KK, Kiemeney LA, Vermeulen SH, Wiencke JK, Walsh KM, Wrensch M, Rice T, Turnbull C, Litchfield K, Paternoster L, Standl M, Abecasis GR, SanGiovanni JP, Li Y, Mijatovic V, Sapkota Y, Low SK, Zondervan KT, Montgomery GW, Nyholt DR, van Heel DA, Hunt K, Arking DE, Ashar FN, Sotoodehnia N, Woo D, Rosand J, Comeau ME, Brown WM, Silverman EK, Hokanson JE, Cho MH, Hui J, Ferreira MA, Thompson PJ, Morrison AC, Felix JF, Smith NL, Christiano AM, Petukhova L, Betz RC, Fan X, Zhang X, Zhu C, Langefeld CD, Thompson SD, Wang F, Lin X, Schwartz DA, Fingerlin T, Rotter JI, Cotch MF, Jensen RA, Munz M, Dommisch H, Schaefer AS, Han F, Ollila HM, Hillary RP, Albagha O, Ralston SH, Zeng C, Zheng W, Shu XO, Reis A, Uebe S, Hüffmeier U, Kawamura Y, Otowa T, Sasaki T, Hibberd ML, Davila S, Xie G, Siminovitch K, Bei JX, Zeng YX, Försti A, Chen B, Landi S, Franke A, Fischer A, Ellinghaus D, Flores C, Noth I, Ma SF, Foo JN, Liu J, Kim JW, Cox DG, Delattre O, Mirabeau O, Skibola CF, Tang CS, Garcia-Barcelo M, Chang KP, Su WH, Chang YS, Martin NG, Gordon S, Wade TD, Lee C, Kubo M, Cha PC, Nakamura Y, Levy D, Kimura M, Hwang SJ, Hunt S, Spector T, Soranzo N, Manichaikul AW, Barr RG, Kahali B, Speliotes E, Yerges-Armstrong LM, Cheng CY, Jonas JB, Wong TY, Fogh I, Lin K, Powell JF, Rice K, Relton CL, Martin RM, Davey Smith G
Oligomeric lipoprotein PelC guides Pel polysaccharide export across the outer membrane of Pseudomonas aeruginosa.
1. Proc Natl Acad Sci U S A - published February 2, 2017
2. Marmont LS, Rich JD, Whitney JC, Whitfield GB, Almblad H, Robinson H, Parsek MR, Harrison JJ, Howell PL
LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells.
1. Proc Natl Acad Sci U S A - published February 2, 2017
2. Gu M, LaJoie D, Chen OS, von Appen A, Ladinsky MS, Redd MJ, Nikolova L, Bjorkman PJ, Sundquist WI, Ullman KS, Frost A
Synergy of cAMP and calcium signaling pathways in CFTR regulation.
1. Proc Natl Acad Sci U S A - published February 2, 2017
2. Bozoky Z, Ahmadi S, Milman T, Kim TH, Du K, Di Paola M, Pasyk S, Pekhletski R, Keller JP, Bear CE, Forman-Kay JD
Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope.
1. Nat Struct Mol Biol - published February 2, 2017
2. Song I, Gil A, Mishra R, Ghersi D, Selin LK, Stern LJ
Unraveling the CHIP:Hsp70 complex as an information processor for protein quality control.
1. Biochim Biophys Acta Proteins Proteom - published February 1, 2017
2. VanPelt J, Page RC
RB Loss Promotes Prostate Cancer Metastasis.
1. Cancer Res - published February 1, 2017
2. Thangavel C, Boopathi E, Liu Y, Haber A, Ertel A, Bhardwaj A, Addya S, Williams N, Ciment SJ, Cotzia P, Dean JL, Snook A, McNair C, Price M, Hernandez JR, Zhao SG, Birbe R, McCarthy JB, Turley EA, Pienta KJ, Feng FY, Dicker AP, Knudsen KE, Den RB
A Versatile Approach for Site-Specific Lysine Acylation in Proteins.
1. Angew Chem Int Ed Engl - published February 1, 2017
2. Wang ZA, Kurra Y, Wang X, Zeng Y, Lee YJ, Sharma V, Lin H, Dai SY, Liu WR
Advances in the field of single-particle cryo-electron microscopy over the last decade.
1. Nat Protoc - published February 1, 2017
2. Frank J
Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28.
1. Mol Cell - published February 1, 2017
2. Smargon AA, Cox DBT, Pyzocha NK, Zheng K, Slaymaker IM, Gootenberg JS, Abudayyeh OA, Essletzbichler P, Shmakov S, Makarova KS, Koonin EV, Zhang F
Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design.
1. Bioorg Med Chem - published February 1, 2017
2. Miller MS, Maheshwari S, McRobb FM, Kinzler KW, Amzel LM, Vogelstein B, Gabelli SB
Revisiting the tubulin cofactors and Arl2 in the regulation of soluble αβ-tubulin pools and their effect on microtubule dynamics.
1. Mol Biol Cell - published February 1, 2017
2. Al-Bassam J
Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue.
1. Proc Natl Acad Sci U S A - published February 1, 2017
2. Tetone LE, Friedman LJ, Osborne ML, Ravi H, Kyzer S, Stumper SK, Mooney RA, Landick R, Gelles J
Prokaryotic ubiquitin-like protein remains intrinsically disordered when covalently attached to proteasomal target proteins.
1. BMC Struct Biol - published February 1, 2017
2. Barandun J, Damberger FF, Delley CL, Laederach J, Allain FH, Weber-Ban E
Glutamine Amide Flip Elicits Long Distance Allosteric Responses in the LOV Protein Vivid.
1. J Am Chem Soc - published February 1, 2017
2. Ganguly A, Thiel W, Crane BR
Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis.
1. Sci Transl Med - published February 1, 2017
2. Miner JJ, Cook LE, Hong JP, Smith AM, Richner JM, Shimak RM, Young AR, Monte K, Poddar S, Crowe JE Jr, Lenschow DJ, Diamond MS
Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis.
1. EMBO Mol Med - published February 1, 2017
2. Palencia A, Bougdour A, Brenier-Pinchart MP, Touquet B, Bertini RL, Sensi C, Gay G, Vollaire J, Josserand V, Easom E, Freund YR, Pelloux H, Rosenthal PJ, Cusack S, Hakimi MA
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication.
1. PLoS Pathog - published February 1, 2017
2. Kindler E, Gil-Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw HH, Züst R, Hwang M, V'kovski P, Stalder H, Marti S, Habjan M, Cervantes-Barragan L, Elliot R, Karl N, Gaughan C, van Kuppeveld FJ, Silverman RH, Keller M, Ludewig B, Bergmann CC, Ziebuhr J, Weiss SR, Kalinke U, Thiel V
Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization.
1. Nucleic Acids Res - published February 1, 2017
2. Adolph MB, Ara A, Feng Y, Wittkopp CJ, Emerman M, Fraser JS, Chelico L
Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding.
1. Nucleic Acids Res - published February 1, 2017
2. Fitzgerald ME, Rawling DC, Potapova O, Ren X, Kohlway A, Pyle AM
A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
1. ACS Infect Dis - published February 1, 2017
2. Chen H, Coseno M, Ficarro SB, Mansueto MS, Komazin-Meredith G, Boissel S, Filman DJ, Marto JA, Hogle JM, Coen DM
Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
1. Nat Methods - published February 1, 2017
2. de la Cruz MJ, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SK, Hinck CS, Hinck AP, Calero G, Eisenberg D, Gonen T
Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes.
1. Nat Biotechnol - published February 1, 2017
2. Staahl BT, Benekareddy M, Coulon-Bainier C, Banfal AA, Floor SN, Sabo JK, Urnes C, Munares GA, Ghosh A, Doudna JA
Investigations of human myosin VI targeting using optogenetically controlled cargo loading.
1. Proc Natl Acad Sci U S A - published February 1, 2017
2. French AR, Sosnick TR, Rock RS
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
1. Nat Commun - published February 1, 2017
2. Rossey I, Gilman MS, Kabeche SC, Sedeyn K, Wrapp D, Kanekiyo M, Chen M, Mas V, Spitaels J, Melero JA, Graham BS, Schepens B, McLellan JS, Saelens X
Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core.
1. Proc Natl Acad Sci U S A - published February 1, 2017
2. Gates ZP, Baxa MC, Yu W, Riback JA, Li H, Roux B, Kent SB, Sosnick TR
Structure and function of HWE/HisKA2-family sensor histidine kinases.
1. Curr Opin Microbiol - published February 1, 2017
2. Herrou J, Crosson S, Fiebig A
Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors.
1. ACS Infect Dis - published February 1, 2017
2. Garzan A, Willby MJ, Ngo HX, Gajadeera CS, Green KD, Holbrook SY, Hou C, Posey JE, Tsodikov OV, Garneau-Tsodikova S
RNA-based recognition and targeting: sowing the seeds of specificity.
1. Nat Rev Mol Cell Biol - published February 1, 2017
2. Gorski SA, Vogel J, Doudna JA
Conformational Changes in the Activation Loop of Mitochondrial Glutaminase C: A Direct Fluorescence Read-Out that Distinguishes the Binding of Allosteric Inhibitors from Activators.
1. J Biol Chem - published February 1, 2017
2. Stalnecker CA, Erickson JW, Cerione RA
Longitudinal imaging of HIV-1 spread in humanized mice with parallel 3D immunofluorescence and electron tomography.
1. Elife - published February 1, 2017
2. Kieffer C, Ladinsky MS, Ninh A, Galimidi RP, Bjorkman PJ
Descriptive Analysis of Spinal Neuroaxial Injections, Surgical Interventions, and Physical Therapy Utilization for Degenerative Lumbar Spondylolisthesis Within Medicare Beneficiaries from 2000 to 2011.
1. Spine (Phila Pa 1976) - published February 1, 2017
2. Sclafani JA, Constantin A, Ho PS, Akuthota V, Chan L
How HIV-1 entry mechanism and broadly neutralizing antibodies guide structure-based vaccine design.
1. Curr Opin HIV AIDS - published February 1, 2017
2. Pancera M, Changela A, Kwong PD
Subcellular localization and interactions of Infectious Salmon Anemia Virus (ISAV) M1 and NEP as well as host Hsc70.
1. Virol J - published February 1, 2017
2. Zhang W, Cai C, Lin L, Tao YJ, Jin M
microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
1. Nat Commun - published February 1, 2017
2. Hajarnis S, Lakhia R, Yheskel M, Williams D, Sorourian M, Liu X, Aboudehen K, Zhang S, Kersjes K, Galasso R, Li J, Kaimal V, Lockton S, Davis S, Flaten A, Johnson JA, Holland WL, Kusminski CM, Scherer PE, Harris PC, Trudel M, Wallace DP, Igarashi P, Lee EC, Androsavich JR, Patel V
A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis.
1. Nat Commun - published February 1, 2017
2. Feng Q, Zhang C, Lum D, Druso JE, Blank B, Wilson KF, Welm A, Antonyak MA, Cerione RA
A glycosylation benchmark profile for HIV-1 envelope glycoprotein production based on eleven Env trimers.
1. J Virol - published February 1, 2017
2. Go EP, Ding H, Zhang S, Ringe RP, Nicely N, Hua D, Steinbock RT, Golabek M, Alin J, Alam SM, Cupo A, Haynes BF, Kappes JC, Moore JP, Sodroski JG, Desaire H
Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences.
1. J Inherit Metab Dis - published February 1, 2017
2. Wortmann SB, Chen MA, Colombo R, Pontoglio A, Alhaddad B, Botto LD, Yuzyuk T, Coughlin CR, Descartes M, Grűnewald S, Maranda B, Mills PB, Pitt J, Potente C, Rodenburg R, Kluijtmans LA, Sampath S, Pai EF, Wevers RA, Tiller GE, and additional individual contributors.
Mechanisms for initiating cellular DNA replication.
1. Science - published February 1, 2017
2. Bleichert F, Botchan MR, Berger JM
Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV-1) envelope glycoprotein.
1. Virol J - published February 1, 2017
2. Nguyen HT, Madani N, Ding H, Elder E, Princiotto A, Gu C, Darby P, Alin J, Herschhorn A, Kappes JC, Mao Y, Sodroski JG
Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion.
1. Science - published February 1, 2017
2. Lees JA, Messa M, Sun EW, Wheeler H, Torta F, Wenk MR, De Camilli P, Reinisch KM
Diffuse large B-cell lymphoma with concurrent high MYC and BCL2 expression shows evidence of active B-cell receptor signaling by quantitative immunofluorescence.
1. PLoS One - published February 1, 2017
2. Bogusz AM, Kovach AE, Le LP, Feng D, Baxter RH, Sohani AR
PARP1 and Sox2: An Unlikely Team of Pioneers to Conquer the Nucleosome.
1. Mol Cell - published February 1, 2017
2. Gaullier G, Luger K
STRUCTURAL AND MECHANISTIC INSIGHTS INTO HEMOGLOBIN-CATALYZED HYDROGEN SULFIDE OXIDATION AND THE FATE OF POLYSULFIDE PRODUCTS.
1. J Biol Chem - published February 1, 2017
2. Vitvitsky V, Yadav PK, An S, Seravalli J, Cho US, Banerjee R
The experiences of a biochemist in the evolving world of G protein-dependent signaling.
1. Cell Signal - published February 1, 2017
2. Cerione RA
Clinical significance of circulating tumor cells in patients with small-cell lung cancer.
1. Tumori - published February 1, 2017
2. Wang YL, Liu CH, Li J, Ma XP, Gong P
Multivariate Analyses of Quality Metrics for Crystal Structures in the PDB Archive.
1. Structure - published February 1, 2017
2. Shao C, Yang H, Westbrook JD, Young JY, Zardecki C, Burley SK
Structural Insights into a Unique Dimeric DEAD-Box Helicase CshA that Promotes RNA Decay.
1. Structure - published February 1, 2017
2. Huen J, Lin CL, Golzarroshan B, Yi WL, Yang WZ, Yuan HS
Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.
1. Sci Adv - published February 1, 2017
2. Kalas V, Pinkner JS, Hannan TJ, Hibbing ME, Dodson KW, Holehouse AS, Zhang H, Tolia NH, Gross ML, Pappu RV, Janetka J, Hultgren SJ
Structural biology of solute carrier (SLC) membrane transport proteins.
1. Mol Membr Biol - published February 1, 2017
2. Bai X, Moraes TF, Reithmeier RAF
Recent advancements in the discovery of protein-protein interaction inhibitors of replication protein A.
1. Medchemcomm - published February 1, 2017
2. Patrone JD, Waterson AG, Fesik SW