Member Publications

Jump to specific year:

135 Member Publications for May 2016

RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor.
1. Cell Rep - published May 31, 2016
2. Sebestyen Z, Scheper W, Vyborova A, Gu S, Rychnavska Z, Schiffler M, Cleven A, Chéneau C, van Noorden M, Peigné CM, Olive D, Lebbink RJ, Oostvogels R, Mutis T, Schuurhuis GJ, Adams EJ, Scotet E, Kuball J
Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques.
1. Proc. Natl. Acad. Sci. U.S.A. - published May 31, 2016
2. Li H, Wang S, Kong R, Ding W, Lee FH, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang GY, Gorman J, Gardner M, Lewis MG, Hatziioannou T, Santra S, Apetrei C, Pandrea I, Alam SM, Liao HX, Shen X, Tomaras GD, Farzan M, Chertova E, Keele BF, Estes JD, Lifson JD, Doms RW, Montefiori DC, Haynes BF, Sodroski JG, Kwong PD, Hahn BH, Shaw GM
Descriptive Analysis of Spinal Neuroaxial Injections, Surgical Interventions and Physical Therapy Utilization for Degenerative Lumbar Spondylolisthesis within Medicare Beneficiaries from 2000-2011.
1. Spine - published May 31, 2016
2. Sclafani JA, Constantin A, Ho PS, Akuthota V, Chan L
A dual molecular analogue tuner for dissecting protein function in mammalian cells.
1. Nat Commun - published May 28, 2016
2. Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka IR
Crystal Structure of the FERM-SH2 Module of Human Jak2.
1. PLoS ONE - published May 27, 2016
2. McNally R, Toms AV, Eck MJ
Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction.
1. Elife - published May 26, 2016
2. Laxmikanthan G, Xu C, Brilot AF, Warren D, Steele L, Seah N, Tong W, Grigorieff N, Landy A, Van Duyne GD
A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV.
1. PLoS ONE - published May 26, 2016
2. Wen X, Pickens J, Mousa JJ, Leser GP, Lamb RA, Crowe JE, Jardetzky TS
Molecular Architecture of Yeast Chromatin Assembly Factor 1.
1. Sci Rep - published May 26, 2016
2. Kim D, Setiaputra D, Jung T, Chung J, Leitner A, Yoon J, Aebersold R, Hebert H, Yip CK, Song JJ
Structural evidence for Nap1-dependent H2A-H2B deposition and nucleosome assembly.
1. EMBO J. - published May 25, 2016
2. Aguilar-Gurrieri C, Larabi A, Vinayachandran V, Patel NA, Yen K, Reja R, Ebong IO, Schoehn G, Robinson CV, Pugh BF, Panne D
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.
1. Nature - published May 25, 2016
2. Jia Y, Yun CH, Park E, Ercan D, Manuia M, Juarez J, Xu C, Rhee K, Chen T, Zhang H, Palakurthi S, Jang J, Lelais G, DiDonato M, Bursulaya B, Michellys PY, Epple R, Marsilje TH, McNeill M, Lu W, Harris J, Bender S, Wong KK, Jänne PA, Eck MJ
Microvesicles released from tumor cells disrupt epithelial cell morphology and contractility.
1. J Biomech - published May 24, 2016
2. Bordeleau F, Chan B, Antonyak MA, Lampi MC, Cerione RA, Reinhart-King CA
Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
1. J. Med. Chem. - published May 24, 2016
2. Zhu J, Caflisch A
ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels.
1. ACS Chem Neurosci - published May 24, 2016
2. Swale DR, Kurata H, Kharade SV, Sheehan J, Raphemot R, Voigtritter KR, Figueroa EE, Meiler J, Blobaum AL, Lindsley CW, Hopkins CR, Denton JS
Functional Synergy between the Munc13 C-terminal C1 and C2 domains.
1. Elife - published May 23, 2016
2. Liu X, Seven AB, Camacho M, Esser V, Xu J, Trimbuch T, Quade B, Su L, Ma C, Rosenmund C, Rizo J
Extracellular Vesicles: Satellites of Information Transfer in Cancer and Stem Cell Biology.
1. Dev. Cell - published May 23, 2016
2. Desrochers LM, Antonyak MA, Cerione RA
Taxonomy of the order Mononegavirales: update 2016.
1. Arch. Virol. - published May 23, 2016
2. Afonso CL, Amarasinghe GK, Bányai K, Bào Y, Basler CF, Bavari S, Bejerman N, Blasdell KR, Briand FX, Briese T, Bukreyev A, Calisher CH, Chandran K, Chéng J, Clawson AN, Collins PL, Dietzgen RG, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Farkas SL, Freitas-Astúa J, Formenty P, Fouchier RA, Fù Y, Ghedin E, Goodin MM, Hewson R, Horie M, Hyndman TH, Jiāng D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lenardon S, Leroy EM, Li CX, Lin XD, Liú L, Longdon B, Marton S, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Randall RE, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Shi M, Smither SJ, Stenglein MD, Stone DM, Takada A, Terregino C, Tesh RB, Tian JH, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Verbeek M, Volchkov VE, Wahl-Jensen V, Walsh JA, Walker PJ, Wang D, Wang LF, Wetzel T, Whitfield AE, Xiè JT, Yuen KY, Zhang YZ, Kuhn JH
Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles.
1. EMBO J. - published May 23, 2016
2. Marzahn MR, Marada S, Lee J, Nourse A, Kenrick S, Zhao H, Ben-Nissan G, Kolaitis RM, Peters JL, Pounds S, Errington WJ, Privé GG, Taylor JP, Sharon M, Schuck P, Ogden SK, Mittag T
Structure Determination of the Nuclear Pore Complex with Three-Dimensional Cryo electron Microscopy.
1. J. Mol. Biol. - published May 22, 2016
2. von Appen A, Beck M
The Structure Inventory of the Nuclear Pore Complex.
1. J. Mol. Biol. - published May 22, 2016
2. Schwartz TU
Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.
1. Nat Commun - published May 20, 2016
2. Pennington LF, Tarchevskaya S, Brigger D, Sathiyamoorthy K, Graham MT, Nadeau KC, Eggel A, Jardetzky TS
Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
1. PLoS ONE - published May 20, 2016
2. Wu X, Indzhykulian AA, Niksch PD, Webber RM, Garcia-Gonzalez M, Watnick T, Zhou J, Vollrath MA, Corey DP
Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy.
1. Signal Transduct Target Ther - published May 20, 2016
2. Wert KJ, Mahajan VB, Zhang L, Yan Y, Li Y, Tosi J, Hsu CW, Nagasaki T, Janisch KM, Grant MB, Mahajan M, Bassuk AG, Tsang SH
HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.
1. Science - published May 20, 2016
2. Schoofs T, Klein F, Braunschweig M, Kreider EF, Feldmann A, Nogueira L, Oliveira T, Lorenzi JC, Parrish EH, Learn GH, West AP, Bjorkman PJ, Schlesinger SJ, Seaman MS, Czartoski J, McElrath MJ, Pfeifer N, Hahn BH, Caskey M, Nussenzweig MC
Preprints for the life sciences.
1. Science - published May 20, 2016
2. Berg JM, Bhalla N, Bourne PE, Chalfie M, Drubin DG, Fraser JS, Greider CW, Hendricks M, Jones C, Kiley R, King S, Kirschner MW, Krumholz HM, Lehmann R, Leptin M, Pulverer B, Rosenzweig B, Spiro JE, Stebbins M, Strasser C, Swaminathan S, Turner P, Vale RD, VijayRaghavan K, Wolberger C
CRISPR repair reveals causative mutation in a preclinical model of retinitis pigmentosa.
1. Mol. Ther. - published May 20, 2016
2. Wu WH, Tsai YT, Justus S, Lee TT, Zhang L, Lin CS, Bassuk AG, Mahajan VB, Tsang SH
Passive Membrane Permeability of Macrocycles Can Be Controlled by Exocyclic Amide Bonds.
1. J. Med. Chem. - published May 19, 2016
2. Hickey JL, Zaretsky S, St Denis MA, Kumar Chakka S, Morshed MM, Scully CC, Roughton AL, Yudin AK
Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection.
1. PLoS Comput. Biol. - published May 19, 2016
2. Sheng Z, Schramm CA, Connors M, Morris L, Mascola JR, Kwong PD, Shapiro L
Inhibition of Propionibacterium acnes associated biofilm formation by Decanediol.
1. J. Dermatol. Sci. - published May 19, 2016
2. Sulzberger M, Fölster H, Sattler M, Rippke F, Grönniger E
Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.
1. Struct Dyn - published May 19, 2016
2. Cao H, Tan K, Wang F, Bigelow L, Yennamalli RM, Jedrzejczak R, Babnigg G, Bingman CA, Joachimiak A, Kharel MK, Singh S, Thorson JS, Phillips GN
Characterization of the Cadherin-Catenin Complex of the Sea Anemone Nematostella vectensis and Implications for the Evolution of Metazoan Cell-Cell Adhesion.
1. Mol. Biol. Evol. - published May 19, 2016
2. Clarke DN, Miller PW, Lowe CJ, Weis WI, Nelson WJ
A decahaem cytochrome as an electron conduit in protein-enzyme redox processes.
1. Chem. Commun. (Camb.) - published May 19, 2016
2. Lee CY, Reuillard B, Sokol KP, Laftsoglou T, Lockwood CW, Rowe SF, Hwang ET, Fontecilla-Camps JC, Jeuken LJ, Butt JN, Reisner E
CRL4(WDR23)-Mediated SLBP Ubiquitylation Ensures Histone Supply during DNA Replication.
1. Mol. Cell - published May 19, 2016
2. Brodersen MM, Lampert F, Barnes CA, Soste M, Piwko W, Peter M
Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.
1. Mol. Cell - published May 19, 2016
2. Békés M, van der Heden van Noort GJ, Ekkebus R, Ovaa H, Huang TT, Lima CD
Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
1. Mol. Cell - published May 19, 2016
2. Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D, Cusack S
Enzymes required for the biosynthesis of N-formylated sugars.
1. Curr. Opin. Struct. Biol. - published May 19, 2016
2. Holden HM, Thoden JB, Gilbert M
Rational Design of Calpain Inhibitors Based on Calpastatin Peptidomimetics.
1. J. Med. Chem. - published May 18, 2016
2. Low KE, Ler S, Chen KJ, Campbell RL, Hickey JL, Tan J, Scully CC, Davies PL, Yudin AK, Zaretsky S
Structural Basis of Diverse Homophilic Recognition by Clustered α- and β-Protocadherins.
1. Neuron - published May 18, 2016
2. Goodman KM, Rubinstein R, Thu CA, Bahna F, Mannepalli S, Ahlsén G, Rittenhouse C, Maniatis T, Honig B, Shapiro L
Overexpression and oncogenic function of HMGA2 in endometrial serous carcinogenesis.
1. Am J Cancer Res - published May 18, 2016
2. Wei L, Liu X, Zhang W, Wei Y, Li Y, Zhang Q, Dong R, Kwon JS, Liu Z, Zheng W, Kong B
Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein.
1. Proc. Natl. Acad. Sci. U.S.A. - published May 18, 2016
2. Chen E, Salinas ND, Huang Y, Ntumngia F, Plasencia MD, Gross ML, Adams JH, Tolia NH
Systematic protein-protein interaction analysis reveals inter-subcomplex contacts in the nuclear pore complex.
1. Mol. Cell Proteomics - published May 18, 2016
2. Apelt L, Knockenhauer KE, Leksa NC, Benlasfer N, Schwartz TU, Stelzl U
HIV frameshift site RNA stability correlates with frameshift efficiency and decreased viral infectivity.
1. J. Virol. - published May 18, 2016
2. Garcia-Miranda P, Becker JT, Benner BE, Blume A, Sherer NM, Butcher SE
Reproducibility will only come with data liberation.
1. Sci Transl Med - published May 18, 2016
2. AlQuraishi M, Sorger PK
BESTROPHIN1 mutations cause defective chloride conductance in patient stem cell-derived RPE.
1. Hum. Mol. Genet. - published May 18, 2016
2. Moshfegh Y, Velez G, Li Y, Bassuk AG, Mahajan VB, Tsang SH
Drug conjugated nanoparticles activated by cancer cell specific mRNA.
1. Oncotarget - published May 18, 2016
2. Gossai NP, Naumann JA, Li NS, Zamora EA, Gordon DJ, Piccirilli JA, Gordon PM
Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based Restraints.
1. PLoS ONE - published May 17, 2016
2. Finn JA, Koehler Leman J, Willis JR, Cisneros A, Crowe JE, Meiler J
The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
1. J. Struct. Biol. - published May 17, 2016
2. Figueroa M, Sleutel M, Vandevenne M, Parvizi G, Attout S, Jacquin O, Vandenameele J, Fischer AW, Damblon C, Goormaghtigh E, Valerio-Lepiniec M, Urvoas A, Durand D, Pardon E, Steyaert J, Minard P, Maes D, Meiler J, Matagne A, Martial JA, Van de Weerdt C
Structural analysis of an active fungal PRC2.
1. Nucleus - published May 17, 2016
2. Jiao L, Liu X
Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril.
1. Proc. Natl. Acad. Sci. U.S.A. - published May 16, 2016
2. Schmidt A, Annamalai K, Schmidt M, Grigorieff N, Fändrich M
The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects.
1. Clin. Cancer Res. - published May 15, 2016
2. Shahbazi J, Liu PY, Atmadibrata B, Bradner JE, Marshall GM, Lock RB, Liu T
Discovery of biaryls as RORγ inverse agonists by using structure-based design.
1. Bioorg. Med. Chem. Lett. - published May 15, 2016
2. Enyedy IJ, Powell NA, Caravella J, van Vloten K, Chao J, Banerjee D, Marcotte D, Silvian L, McKenzie A, Hong VS, Fontenot JD
Biochemical Basis of Sestrin Physiological Activities.
1. Trends Biochem. Sci. - published May 14, 2016
2. Ho A, Cho CS, Namkoong S, Cho US, Lee JH
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
1. Science - published May 13, 2016
2. Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, Druz A, Georgiev IS, Gorman J, Huang J, Joyce MG, Louder MK, Ma X, McKee K, O'Dell S, Pancera M, Yang Y, Blanchard SC, Mothes W, Burton DR, Koff WC, Connors M, Ward AB, Kwong PD, Mascola JR
Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.
1. J. Am. Chem. Soc. - published May 12, 2016
2. Meisburger SP, Taylor AB, Khan CA, Zhang S, Fitzpatrick PF, Ando N
Structure and Activities of the Eukaryotic RNA Exosome.
1. Enzymes - published May 12, 2016
2. Wasmuth EV, Lima CD
25 Years of Tension over Actin Binding to the Cadherin Cell Adhesion Complex: The Devil is in the Details.
1. Trends Cell Biol. - published May 12, 2016
2. Nelson WJ, Weis WI
The AUDANA algorithm for automated protein 3D structure determination from NMR NOE data.
1. J. Biomol. NMR - published May 12, 2016
2. Lee W, Petit CM, Cornilescu G, Stark JL, Markley JL
Structure of the Escherichia coli ArnA N-Formyltransferase Domain in Complex with N(5) -formyltetrahydrofolate and UDP-Ara4N.
1. Protein Sci. - published May 12, 2016
2. Genthe NA, Thoden JB, Holden HM
A benchmark testing ground for integrating homology modeling and protein docking.
1. Proteins - published May 12, 2016
2. Bohnuud T, Luo L, Wodak SJ, Bonvin AM, Weng Z, Vajda S, Schueler-Furman O, Kozakov D
Cell-free translation and purification of Arabidopsis thaliana regulator of G signaling 1 protein.
1. Protein Expr. Purif. - published May 11, 2016
2. Li B, Makino S, Beebe ET, Urano D, Aceti DJ, Misenheimer TM, Peters J, Fox BG, Jones AM
Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.
1. Oncotarget - published May 10, 2016
2. Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, Warnatz HJ, Yaspo ML, Adams CM, Leib RD, Breese M, Marra MA, Malkin D, Lichter P, Doudna JA, Pfister SM, Taylor MD, Chang HY, Cho YJ
Photoelectrochemical H2 Evolution with a Hydrogenase Immobilized on a TiO2 -Protected Silicon Electrode.
1. Angew. Chem. Int. Ed. Engl. - published May 10, 2016
2. Lee CY, Park HS, Fontecilla-Camps JC, Reisner E
Aminoacetylation Reaction Catalyzed by Leucyl-tRNA Synthetase Operates via a Self-Assisted Mechanism Using a Conserved Residue and the Aminoacyl Substrate.
1. J Phys Chem B - published May 10, 2016
2. Aleksandrov A, Palencia A, Cusack S, Field M
The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex.
1. Angew. Chem. Int. Ed. Engl. - published May 10, 2016
2. Salvi N, Papadopoulos E, Blackledge M, Wagner G
Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.
1. Anesth. Analg. - published May 10, 2016
2. Forman SA, Miller KW
Photoelectrochemical H2 Evolution with a Hydrogenase Immobilized on a TiO2-Protected Silicon Electrode.
1. Angew Chem Weinheim Bergstr Ger - published May 10, 2016
2. Lee CY, Park HS, Fontecilla-Camps JC, Reisner E
Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
1. Oncogene - published May 9, 2016
2. Bernasconi-Elias P, Hu T, Jenkins D, Firestone B, Gans S, Kurth E, Capodieci P, Deplazes-Lauber J, Petropoulos K, Thiel P, Ponsel D, Hee Choi S, LeMotte P, London A, Goetcshkes M, Nolin E, Jones MD, Slocum K, Kluk MJ, Weinstock DM, Christodoulou A, Weinberg O, Jaehrling J, Ettenberg SA, Buckler A, Blacklow SC, Aster JC, Fryer CJ
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
1. Elife - published May 9, 2016
2. Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA
Allosteric inhibition of antiapoptotic MCL-1.
1. Nat. Struct. Mol. Biol. - published May 9, 2016
2. Lee S, Wales TE, Escudero S, Cohen DT, Luccarelli J, Gallagher CG, Cohen NA, Huhn AJ, Bird GH, Engen JR, Walensky LD
Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations.
1. Proc. Natl. Acad. Sci. U.S.A. - published May 9, 2016
2. Sun X, Park JH, Gumerson J, Wu Z, Swaroop A, Qian H, Roll-Mecak A, Li T
"The UbiI (VisC) aerobic ubiquinone synthase is required for expression of type 1 pili, biofilm formation, and pathogenesis in uropathogenic Escherichia coli".
1. J. Bacteriol. - published May 9, 2016
2. Floyd KA, Mitchell CA, Eberly AR, Colling SJ, Zhang EW, DePas W, Chapman MR, Conover M, Rogers BR, Hultgren SJ, Hadjifrangiskou M
Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma.
1. Cancer Cell - published May 9, 2016
2. Lu F, Chen Y, Zhao C, Wang H, He D, Xu L, Wang J, He X, Deng Y, Lu EE, Liu X, Verma R, Bu H, Drissi R, Fouladi M, Stemmer-Rachamimov AO, Burns D, Xin M, Rubin JB, Bahassi el M, Canoll P, Holland EC, Lu QR
Recent Advances in Deciphering the Structure and Molecular Mechanism of the AAA+ ATPase N-Ethylmaleimide-Sensitive Factor (NSF).
1. J. Mol. Biol. - published May 8, 2016
2. Zhao M, Brunger AT
Meiotic Clade AAA ATPases: Protein Polymer Disassembly Machines.
1. J. Mol. Biol. - published May 8, 2016
2. Monroe N, Hill CP
Regulation of Microtubule Assembly by Tau and not by Pin1.
1. J. Mol. Biol. - published May 8, 2016
2. Kutter S, Eichner T, Deaconescu AM, Kern D
Editorial Overview: Molecular Mechanisms of Autophagy-Part A.
1. J. Mol. Biol. - published May 8, 2016
2. Hurley JH
Mechanisms and Functional Diversity of Macromolecular Remodeling by ATP-Dependent Motors.
1. J. Mol. Biol. - published May 8, 2016
2. Martin A, Berger JM, Sellers JR, Ostankovitch M
MNase titration reveals differences between nucleosome occupancy and chromatin accessibility.
1. Nat Commun - published May 7, 2016
2. Mieczkowski J, Cook A, Bowman SK, Mueller B, Alver BH, Kundu S, Deaton AM, Urban JA, Larschan E, Park PJ, Kingston RE, Tolstorukov MY
Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin.
1. PLoS ONE - published May 7, 2016
2. Xia Y, Li Y, Westover KD, Sun J, Chen H, Zhang J, Fisher DE
High-Efficiency Isolation of Nuclear Envelope Protein Complexes from Trypanosomes.
1. Methods Mol Biol - published May 6, 2016
2. Obado SO, Field MC, Chait BT, Rout MP
Estimation of Uncertainties in the Global Distance Test (GDT_TS) for CASP Models.
1. PLoS One - published May 6, 2016
2. Li W, Schaeffer RD, Otwinowski Z, Grishin NV
Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case.
1. Cold Spring Harb Mol Case Stud - published May 6, 2016
2. Knoechel B, Bhatt A, Pan L, Pedamallu CS, Severson E, Gutierrez A, Dorfman DM, Kuo FC, Kluk M, Kung AL, Zweidler-McKay P, Meyerson M, Blacklow SC, DeAngelo DJ, Aster JC
Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution.
1. Nucleic Acids Res. - published May 5, 2016
2. Hwang CS, Xu L, Wang W, Ulrich S, Zhang L, Chong J, Shin JH, Huang X, Kool ET, McKenna CE, Wang D
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA.
1. Cell - published May 5, 2016
2. Yamano T, Nishimasu H, Zetsche B, Hirano H, Slaymaker IM, Li Y, Fedorova I, Nakane T, Makarova KS, Koonin EV, Ishitani R, Zhang F, Nureki O
Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.
1. Cell - published May 5, 2016
2. Stewart-Jones GB, Soto C, Lemmin T, Chuang GY, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens AJ, Bylund T, Choi CW, Davison JR, Georgiev IS, Joyce MG, Kwon YD, Pancera M, Taft J, Yang Y, Zhang B, Shivatare SS, Shivatare VS, Lee CC, Wu CY, Bewley CA, Burton DR, Koff WC, Connors M, Crispin M, Baxa U, Korber BT, Wong CH, Mascola JR, Kwong PD
Complication of Autologous Stem Cell Transplantation in Retinitis Pigmentosa.
1. JAMA Ophthalmol - published May 5, 2016
2. Boudreault K, Justus S, Lee W, Mahajan VB, Tsang SH
ACANTHAMOEBA ENDOPHTHALMITIS AFTER RECURRENT KERATITIS AND NODULAR SCLERITIS.
1. Retin Cases Brief Rep - published May 5, 2016
2. Mammo Z, Almeida DR, Cunningham MA, Chin EK, Mahajan VB
Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.
1. Mol. Cell - published May 5, 2016
2. Hamill S, Lou HJ, Turk BE, Boggon TJ
The N-terminus of the Vaccinia Virus protein F1L is an Intrinsically Unstructured Region that is not involved in Apoptosis Regulation.
1. J. Biol. Chem. - published May 5, 2016
2. Caria S, Marshall B, Burton RL, Campbell S, Pantaki-Eimany D, Hawkins CJ, Barry M, Kvansakul M
The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones.
1. PLoS Genet. - published May 4, 2016
2. Truttmann MC, Cruz VE, Guo X, Engert C, Schwartz TU, Ploegh HL
Anti-CCR4 monoclonal antibody enhances antitumor immunity by modulating tumor-infiltrating Tregs in an ovarian cancer xenograft humanized mouse model.
1. Oncoimmunology - published May 4, 2016
2. Chang DK, Peterson E, Sun J, Goudie C, Drapkin RI, Liu JF, Matulonis U, Zhu Q, Marasco WA
Activation of the A2A adenosine G-protein-coupled receptor by conformational selection.
1. Nature - published May 4, 2016
2. Ye L, Van Eps N, Zimmer M, Ernst OP, Prosser RS
Crystal structure of the human sterol transporter ABCG5/ABCG8.
1. Nature - published May 4, 2016
2. Lee JY, Kinch LN, Borek DM, Wang J, Wang J, Urbatsch IL, Xie XS, Grishin NV, Cohen JC, Otwinowski Z, Hobbs HH, Rosenbaum DM
COMBINED VITRECTOMY AND INTRAVITREAL DEXAMETHASONE (OZURDEX) SUSTAINED-RELEASE IMPLANT.
1. Retina (Philadelphia, Pa.) - published May 4, 2016
2. Zheng A, Chin EK, Almeida DR, Tsang SH, Mahajan VB
Structural Basis for the Magnesium-Dependent Activation and Hexamerization of the Lon AAA+ Protease.
1. Structure - published May 3, 2016
2. Su SC, Lin CC, Tai HC, Chang MY, Ho MR, Babu CS, Liao JH, Wu SH, Chang YC, Lim C, Chang CI
Structural Insights into the Allosteric Operation of the Lon AAA+ Protease.
1. Structure - published May 3, 2016
2. Lin CC, Su SC, Su MY, Liang PH, Feng CC, Wu SH, Chang CI
Structural Basis for Substrate Selectivity of the E3 Ligase COP1.
1. Structure - published May 3, 2016
2. Uljon S, Xu X, Durzynska I, Stein S, Adelmant G, Marto JA, Pear WS, Blacklow SC
Manipulation of Subunit Stoichiometry in Heteromeric Membrane Proteins.
1. Structure - published May 3, 2016
2. Morales-Perez CL, Noviello CM, Hibbs RE
Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
1. Biochemistry - published May 3, 2016
2. Fenwick MK, Philmus B, Begley TP, Ealick SE
Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex.
1. Proc Natl Acad Sci U S A - published May 3, 2016
2. Raveh B, Karp JM, Sparks S, Dutta K, Rout MP, Sali A, Cowburn D
Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii.
1. Biochemistry - published May 3, 2016
2. Guo Q, Gakhar L, Wickersham K, Francis K, Vardi-Kilshtain A, Major DT, Cheatum CM, Kohen A
Architecture and Nucleotide-Dependent Conformational Changes of the Rvb1-Rvb2 AAA+ Complex Revealed by Cryoelectron Microscopy.
1. Structure - published May 3, 2016
2. Ewens CA, Su M, Zhao L, Nano N, Houry WA, Southworth DR
Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation.
1. Structure - published May 3, 2016
2. Matulef K, Annen AW, Nix JC, Valiyaveetil FI
Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.
1. Proc Natl Acad Sci U S A - published May 3, 2016
2. Bakkers MJ, Zeng Q, Feitsma LJ, Hulswit RJ, Li Z, Westerbeke A, van Kuppeveld FJ, Boons GJ, Langereis MA, Huizinga EG, de Groot RJ
Identification of a Paralog-Specific Notch1 Intracellular Domain Degron.
1. Cell Rep - published May 3, 2016
2. Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E
Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity.
1. Elife - published May 3, 2016
2. Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E
Directly Activating the Integrin αIIbβ3 Initiates Outside-In Signaling by Causing αIIbβ3 Clustering.
1. J Biol Chem - published May 2, 2016
2. Fong KP, Zhu H, Span LM, Moore DT, Yoon K, Tamura R, Yin H, DeGrado WF, Bennett JS
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
1. J Exp Med - published May 2, 2016
2. Wang Y, Ulland TK, Ulrich JD, Song W, Tzaferis JA, Hole JT, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, Grutzendler J, DeMattos RB, Cirrito JR, Holtzman DM, Colonna M
Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa.
1. J Med Chem - published May 2, 2016
2. Kitamura S, Hvorecny KL, Niu J, Hammock BD, Madden DR, Morisseau C
Subnanometer Structure of an Asymmetric Model Membrane: Interleaflet Coupling Influences Domain Properties.
1. Langmuir - published May 2, 2016
2. Heberle FA, Marquardt D, Doktorova M, Geier B, Standaert RF, Heftberger P, Kollmitzer B, Nickels JD, Dick RA, Feigenson GW, Katsaras J, London E, Pabst G
Activation of NMDA receptors and the mechanism of inhibition by ifenprodil.
1. Nature - published May 2, 2016
2. Tajima N, Karakas E, Grant T, Simorowski N, Diaz-Avalos R, Grigorieff N, Furukawa H
Architecture of the mitochondrial calcium uniporter.
1. Nature - published May 2, 2016
2. Oxenoid K, Dong Y, Cao C, Cui T, Sancak Y, Markhard AL, Grabarek Z, Kong L, Liu Z, Ouyang B, Cong Y, Mootha VK, Chou JJ
Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair.
1. Radiat. Res. - published May 2, 2016
2. Udayakumar D, Pandita RK, Horikoshi N, Liu Y, Liu Q, Wong KK, Hunt CR, Gray NS, Minna JD, Pandita TK, Westover KD
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs.
1. Nat. Methods - published May 2, 2016
2. Hafner M, Niepel M, Chung M, Sorger PK
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.
1. Nat. Med. - published May 2, 2016
2. Souroullas GP, Jeck WR, Parker JS, Simon JM, Liu JY, Paulk J, Xiong J, Clark KS, Fedoriw Y, Qi J, Burd CE, Bradner JE, Sharpless NE
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch.
1. Nat. Biotechnol. - published May 2, 2016
2. Oakes BL, Nadler DC, Flamholz A, Fellmann C, Staahl BT, Doudna JA, Savage DF
Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
1. Nat. Struct. Mol. Biol. - published May 2, 2016
2. Zhao C, Pyle AM
Design of a Genetically Stable High-Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in vivo.
1. J. Biol. Chem. - published May 2, 2016
2. McDonald S, Block A, Beaucourt S, Moratorio G, Vignuzzi M, Peersen OB
Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
1. J Am Chem Soc - published May 2, 2016
2. Kreitler DF, Mortenson DE, Forest KT, Gellman SH
Curcumin induces ER stress-mediated apoptosis through selective generation of reactive oxygen species in cervical cancer cells.
1. Mol Carcinog - published May 1, 2016
2. Kim B, Kim HS, Jung EJ, Lee JY, K Tsang B, Lim JM, Song YS
Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation.
1. Haematologica - published May 1, 2016
2. Engelhardt BG, Paczesny S, Jung DK, Daguindau E, Jagasia M, Savani BN, Chinratanalab W, Cornell RF, Goodman S, Greer JP, Kassim AA, Sengsayadeth S, Yoder SM, Rock MT, Crowe JE Jr
Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C.
1. Antimicrob Agents Chemother - published May 1, 2016
2. Ulferts R, de Boer SM, van der Linden L, Bauer L, Lyoo HR, Maté MJ, Lichière J, Canard B, Lelieveld D, Omta W, Egan D, Coutard B, van Kuppeveld FJ
A method for measuring binding constants using unpurified in vivo biotinylated ligands.
1. Anal Biochem - published May 1, 2016
2. Pogoutse AK, Lai CC, Ostan N, Yu RH, Schryvers AB, Moraes TF
The value of preoperative liver biopsy in the diagnosis of extrahepatic biliary atresia: A systematic review and meta-analysis.
1. J Pediatr Surg - published May 1, 2016
2. Lee JY, Sullivan K, El Demellawy D, Nasr A
Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1.
1. J Virol - published May 1, 2016
2. Messer WB, Yount BL, Royal SR, de Alwis R, Widman DG, Smith SA, Crowe JE Jr, Pfaff JM, Kahle KM, Doranz BJ, Ibarra KD, Harris E, de Silva AM, Baric RS
Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein.
1. Nat Struct Mol Biol - published May 1, 2016
2. Tuttle MD, Comellas G, Nieuwkoop AJ, Covell DJ, Berthold DA, Kloepper KD, Courtney JM, Kim JK, Barclay AM, Kendall A, Wan W, Stubbs G, Schwieters CD, Lee VM, George JM, Rienstra CM
Systematic Identification of Protein-Metabolite Interactions in Complex Metabolite Mixtures by Ligand-Detected Nuclear Magnetic Resonance Spectroscopy.
1. Biochemistry - published May 1, 2016
2. Nikolaev YV, Kochanowski K, Link H, Sauer U, Allain FH
Mechanism of APC/CCDC20 activation by mitotic phosphorylation.
1. Proc Natl Acad Sci U S A - published May 1, 2016
2. Qiao R, Weissmann F, Yamaguchi M, Brown NG, VanderLinden R, Imre R, Jarvis MA, Brunner MR, Davidson IF, Litos G, Haselbach D, Mechtler K, Stark H, Schulman BA, Peters JM
The Myb domain of LUX ARRHYTHMO in complex with DNA: expression, purification and crystallization.
1. Acta Crystallogr F Struct Biol Commun - published May 1, 2016
2. Silva CS, Lai X, Nanao M, Zubieta C
Structural analysis of cofactor binding for a prolyl 4-hydroxylase from the pathogenic bacterium Bacillus anthracis.
1. Acta Crystallogr D Struct Biol - published May 1, 2016
2. Schnicker NJ, Dey M
Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses.
1. Invest. Ophthalmol. Vis. Sci. - published May 1, 2016
2. Schaefer KA, Toral MA, Velez G, Cox AJ, Baker SA, Borcherding NC, Colgan DF, Bondada V, Mashburn CB, Yu CG, Geddes JW, Tsang SH, Bassuk AG, Mahajan VB
RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure.
1. Cell - published May 1, 2016
2. Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY
Near-atomic resolution visualization of human transcription promoter opening.
1. Nature - published May 1, 2016
2. He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I, Nogales E
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
1. Neuron - published May 1, 2016
2. Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J
The Structural Relationship between Iterative and Modular PKSs.
1. Cell Chem Biol - published May 1, 2016
2. Keatinge-Clay AT
Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition.
1. Sci Adv - published May 1, 2016
2. Li SA, Cheng L, Yu Y, Wang JH, Chen Q