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104 Member Publications for December 2015

Autocorrelation descriptor improvements for QSAR: 2DA_Sign and 3DA_Sign.
1. J. Comput. Aided Mol. Des. - published December 31, 2015
2. Sliwoski G, Mendenhall J, Meiler J
Immunogenicity of a Prefusion HIV-1-Envelope Trimer in Complex with a Quaternary-Specific Antibody.
1. J. Virol. - published December 30, 2015
2. Cheng C, Pancera M, Bossert A, Schmidt SD, Chen RE, Chen X, Druz A, Narpala S, Doria-Rose NA, McDermott AB, Kwong PD, Mascola JR
The higher level of complexity of K-Ras4B activation at the membrane.
1. FASEB J. - published December 30, 2015
2. Jang H, Banerjee A, Chavan TS, Lu S, Zhang J, Gaponenko V, Nussinov R
Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 29, 2015
2. Reshetnyak AV, Murray PB, Shi X, Mo ES, Mohanty J, Tome F, Bai H, Gunel M, Lax I, Schlessinger J
Immunogenic Stimulus for Germline Precursors of Antibodies that Engage the Influenza Hemagglutinin Receptor-Binding Site.
1. Cell Rep - published December 29, 2015
2. Schmidt AG, Do KT, McCarthy KR, Kepler TB, Liao HX, Moody MA, Haynes BF, Harrison SC
Mechanistic insights into c-di-GMP-dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 28, 2015
2. Matsuyama BY, Krasteva PV, Baraquet C, Harwood CS, Sondermann H, Navarro MV
One-carbon chemistry of oxalate oxidoreductase captured by X-ray crystallography.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 28, 2015
2. Gibson MI, Chen PY, Johnson AC, Pierce E, Can M, Ragsdale SW, Drennan CL
Kinesin-2 KIF3AC: Fast or Slow Either Head Can Start the Processive Run.
1. J. Biol. Chem. - published December 28, 2015
2. Zhang P, Rayment I, Gilbert SP
Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 28, 2015
2. Wong JJ, Paterson RG, Lamb RA, Jardetzky TS
Transient β-hairpin formation in α-synuclein monomer revealed by coarse-grained molecular dynamics simulation.
1. J Chem Phys - published December 28, 2015
2. Yu H, Han W, Ma W, Schulten K
Genome editing: the end of the beginning.
1. Genome Biol. - published December 25, 2015
2. Doudna JA, Gersbach CA
Combination of Ambiguous and Unambiguous Data in the Restraint-driven Docking of Flexible Peptides with HADDOCK: The Binding of the Spider Toxin PcTx1 to the Acid Sensing Ion Channel (ASIC) 1a.
1. J Chem Inf Model - published December 24, 2015
2. Deplazes E, Davies J, Bonvin AM, King GF, Mark AE
Exploring the repeat protein universe through computational protein design.
1. Nature - published December 24, 2015
2. Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D
The Mechanism of Action of Lysobactin.
1. J. Am. Chem. Soc. - published December 24, 2015
2. Lee W, Schaefer K, Qiao Y, Srisuknimit V, Steinmetz H, Müller R, Kahne D, Walker S
Multifunctional cellulase catalysis targeted by fusion to different carbohydrate-binding modules.
1. Biotechnol Biofuels - published December 24, 2015
2. Walker JA, Takasuka TE, Deng K, Bianchetti CM, Udell HS, Prom BM, Kim H, Adams PD, Northen TR, Fox BG
Crystallization of P-type ATPases by the High Lipid-Detergent (HiLiDe) Method.
1. Methods Mol Biol - published December 24, 2015
2. Sitsel O, Wang K, Liu X, Gourdon P
Overproduction of PIB-Type ATPases.
1. Methods Mol Biol - published December 24, 2015
2. Liu X, Sitsel O, Wang K, Gourdon P
Novel Insights into Guide RNA 5'-Nucleoside/Tide Binding by Human Argonaute 2.
1. Int J Mol Sci - published December 24, 2015
2. Kalia M, Willkomm S, Claussen JC, Restle T, Bonvin AM
The roles of the conserved tyrosine in the β2-α2 loop of the prion protein.
1. Prion - published December 23, 2015
2. Huang D, Caflisch A
PSIP1/LEDGF: a new gene likely involved in sensorineural progressive hearing loss.
1. Sci Rep - published December 23, 2015
2. Girotto G, Scheffer DI, Morgan A, Vozzi D, Rubinato E, Di Stazio M, Muzzi E, Pensiero S, Giersch AB, Corey DP, Gasparini P
Structure-function relationships of brazzein variants with altered interactions with the human sweet taste receptor.
1. Protein Sci. - published December 23, 2015
2. Singarapu KK, Tonelli M, Markley JL, Assadi-Porter FM
Conformational states of syntaxin-1 govern the necessity of N-peptide binding in exocytosis of PC12 cells and Caenorhabditis elegans.
1. Mol. Biol. Cell - published December 23, 2015
2. Park S, Bin NR, Michael Rajah M, Kim B, Chou TC, Kang SY, Sugita K, Parsaud L, Smith M, Monnier PP, Ikura M, Zhen M, Sugita S
Efficient Mammalian Cell Expression and Single-step Purification of Extracellular Glycoproteins for Crystallization.
1. J Vis Exp - published December 23, 2015
2. Kober DL, Yurtsever Z, Brett TJ
Structural Basis for Dimerization and DNA Binding of Transcription Factor FLI1.
1. Biochemistry - published December 22, 2015
2. Hou C, Tsodikov OV
TMEM110 regulates the maintenance and remodeling of mammalian ER-plasma membrane junctions competent for STIM-ORAI signaling.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 22, 2015
2. Quintana A, Rajanikanth V, Farber-Katz S, Gudlur A, Zhang C, Jing J, Zhou Y, Rao A, Hogan PG
Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis.
1. Cell Rep - published December 22, 2015
2. Jin J, Liss NM, Chen DH, Liao M, Fox JM, Shimak RM, Fong RH, Chafets D, Bakkour S, Keating S, Fomin ME, Muench MO, Sherman MB, Doranz BJ, Diamond MS, Simmons G
SMP-domain proteins at membrane contact sites: Structure and function.
1. Biochim. Biophys. Acta - published December 22, 2015
2. Reinisch KM, De Camilli P
CO and CN- syntheses by [FeFe]-hydrogenase maturase HydG are catalytically differentiated events.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 22, 2015
2. Pagnier A, Martin L, Zeppieri L, Nicolet Y, Fontecilla-Camps JC
Base-Displaced Intercalated Structure of the N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone DNA Adduct.
1. Chem. Res. Toxicol. - published December 21, 2015
2. Politica DA, Malik CK, Basu AK, Stone MP
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
1. Nat. Struct. Mol. Biol. - published December 21, 2015
2. Gorman J, Soto C, Yang MM, Davenport TM, Guttman M, Bailer RT, Chambers M, Chuang GY, DeKosky BJ, Doria-Rose NA, Druz A, Ernandes MJ, Georgiev IS, Jarosinski MC, Joyce MG, Lemmin TM, Leung S, Louder MK, McDaniel JR, Narpala S, Pancera M, Stuckey J, Wu X, Yang Y, Zhang B, Zhou T, NISC Comparative Sequencing Program, Mullikin JC, Baxa U, Georgiou G, McDermott AB, Bonsignori M, Haynes BF, Moore PL, Morris L, Lee KK, Shapiro L, Mascola JR, Kwong PD
Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis.
1. Dev. Cell - published December 21, 2015
2. McDonald NA, Vander Kooi CW, Ohi MD, Gould KL
Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens.
1. Genet. Mol. Res. - published December 19, 2015
2. Deng B, Yu T, Liu W, Ye SQ, Wang LX, Yang Y, Gong P, Ran ZP, Huang HJ, Wen JH
Structural basis of interprotein electron transfer in bacterial sulfite oxidation.
1. Elife - published December 19, 2015
2. McGrath AP, Laming EL, Casas Garcia GP, Kvansakul M, Guss JM, Trewhella J, Calmes B, Bernhardt PV, Hanson GR, Kappler U, Maher MJ
Structure and membrane remodeling activity of ESCRT-III helical polymers.
1. Science - published December 18, 2015
2. McCullough J, Clippinger AK, Talledge N, Skowyra ML, Saunders MG, Naismith TV, Colf LA, Afonine P, Arthur C, Sundquist WI, Hanson PI, Frost A
SURGICAL EMBOLECTOMY FOR FOVEA-THREATENING ACUTE RETINAL ARTERY OCCLUSION.
1. Retin Cases Brief Rep - published December 18, 2015
2. Almeida DR, Mammo Z, Chin EK, Mahajan VB
NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.
1. Mol. Cell - published December 17, 2015
2. Shen C, Ipsaro JJ, Shi J, Milazzo JP, Wang E, Roe JS, Suzuki Y, Pappin DJ, Joshua-Tor L, Vakoc CR
Contribution of Physical Interactions to Signaling Specificity between a Diguanylate Cyclase and Its Effector.
1. MBio - published December 17, 2015
2. Dahlstrom KM, Giglio KM, Collins AJ, Sondermann H, O'Toole GA
Architecture of human mTOR complex 1.
1. Science - published December 17, 2015
2. Aylett CH, Sauer E, Imseng S, Boehringer D, Hall MN, Ban N, Maier T
Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins.
1. Cell - published December 17, 2015
2. Carrillo RA, Özkan E, Menon KP, Nagarkar-Jaiswal S, Lee PT, Jeon M, Birnbaum ME, Bellen HJ, Garcia KC, Zinn K
Backbone Flexibility Influences Nucleotide Incorporation by Human Translesion DNA Polymerase η opposite Intrastrand Cross-Linked DNA.
1. Biochemistry - published December 16, 2015
2. O'Flaherty DK, Guengerich FP, Egli M, Wilds CJ
Catalysis-dependent selenium incorporation and migration in the nitrogenase active site iron-molybdenum cofactor.
1. Elife - published December 16, 2015
2. Spatzal T, Perez KA, Howard JB, Rees DC
Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 15, 2015
2. Brettmann JB, Urusova D, Tonelli M, Silva JR, Henzler-Wildman KA
Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen.
1. Cell Rep - published December 15, 2015
2. Lopez J, Bittame A, Massera C, Vasseur V, Effantin G, Valat A, Buaillon C, Allart S, Fox BA, Rommereim LM, Bzik DJ, Schoehn G, Weissenhorn W, Dubremetz JF, Gagnon J, Mercier C, Cesbron-Delauw MF, Blanchard N
The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium.
1. Sci Adv - published December 15, 2015
2. Volbeda A, Darnault C, Renoux O, Nicolet Y, Fontecilla-Camps JC
Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.
1. Elife - published December 15, 2015
2. Tang S, Henne WM, Borbat PP, Buchkovich NJ, Freed JH, Mao Y, Fromme JC, Emr SD
Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly.
1. Nucleic Acids Res. - published December 15, 2015
2. Didychuk AL, Montemayor EJ, Brow DA, Butcher SE
The structural diversity of artificial genetic polymers.
1. Nucleic Acids Res. - published December 15, 2015
2. Anosova I, Kowal EA, Dunn MR, Chaput JC, Van Horn WD, Egli M
High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site.
1. Biophys. J. - published December 15, 2015
2. Chavan TS, Jang H, Khavrutskii L, Abraham SJ, Banerjee A, Freed BC, Johannessen L, Tarasov SG, Gaponenko V, Nussinov R, Tarasova NI
Negative membrane curvature catalyzes nucleation of endosomal sorting complex required for transport (ESCRT)-III assembly.
1. Proc. Natl. Acad. Sci. U.S.A. - published December 14, 2015
2. Lee IH, Kai H, Carlson LA, Groves JT, Hurley JH
Herpesvirus gB: A Finely Tuned Fusion Machine.
1. Viruses - published December 11, 2015
2. Cooper RS, Heldwein EE
Molecular structures of unbound and transcribing RNA polymerase III.
1. Nature - published December 10, 2015
2. Hoffmann NA, Jakobi AJ, Moreno-Morcillo M, Glatt S, Kosinski J, Hagen WJ, Sachse C, Müller CW
Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly.
1. PLoS Pathog. - published December 10, 2015
2. Xu K, Chan YP, Bradel-Tretheway B, Akyol-Ataman Z, Zhu Y, Dutta S, Yan L, Feng Y, Wang LF, Skiniotis G, Lee B, Zhou ZH, Broder CC, Aguilar HC, Nikolov DB
Analog sensitive chemical inhibition of the DEAD-box protein DDX3.
1. Protein Sci. - published December 10, 2015
2. Floor SN, Barkovich KJ, Condon KJ, Shokat KM, Doudna JA
Radical-mediated ring contraction in the biosynthesis of 7-deazapurines.
1. Curr. Opin. Struct. Biol. - published December 9, 2015
2. Bandarian V, Drennan CL
A mechanism for the suppression of homologous recombination in G1 cells.
1. Nature - published December 9, 2015
2. Orthwein A, Noordermeer SM, Wilson MD, Landry S, Enchev RI, Sherker A, Munro M, Pinder J, Salsman J, Dellaire G, Xia B, Peter M, Durocher D
Signal transduction in light-oxygen-voltage receptors lacking the adduct-forming cysteine residue.
1. Nat Commun - published December 9, 2015
2. Yee EF, Diensthuber RP, Vaidya AT, Borbat PP, Engelhard C, Freed JH, Bittl R, Möglich A, Crane BR
Ion channels and calcium signaling in motile cilia.
1. Elife - published December 9, 2015
2. Doerner JF, Delling M, Clapham DE
Comparative Mutagenesis of Pseudorabies Virus and Epstein-Barr Virus gH Identifies a Structural Determinant within Domain III of gH Required for Surface Expression and Entry Function.
1. J. Virol. - published December 9, 2015
2. Möhl BS, Schröter C, Klupp BG, Fuchs W, Mettenleiter TC, Jardetzky TS, Longnecker R
Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan.
1. Cell Host Microbe - published December 9, 2015
2. Kolar SL, Kyme P, Tseng CW, Soliman A, Kaplan A, Liang J, Nizet V, Jiang D, Murali R, Arditi M, Underhill DM, Liu GY
Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells.
1. J. Virol. - published December 9, 2015
2. Lee WS, Richard J, Lichtfuss M, Smith AB, Park J, Courter JR, Melillo BN, Sodroski JG, Kaufmann DE, Finzi A, Parsons MS, Kent SJ
Molecular Basis for Antibody-Mediated Neutralization of New World Hemorrhagic Fever Mammarenaviruses.
1. Cell Host Microbe - published December 9, 2015
2. Mahmutovic S, Clark L, Levis SC, Briggiler AM, Enria DA, Harrison SC, Abraham J
Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation.
1. Biochemistry - published December 8, 2015
2. Assimon VA, Southworth DR, Gestwicki JE
Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt.
1. Nat. Struct. Mol. Biol. - published December 8, 2015
2. Murn J, Teplova M, Zarnack K, Shi Y, Patel DJ
Molecular mechanism of respiratory syncytial virus fusion inhibitors.
1. Nat. Chem. Biol. - published December 8, 2015
2. Battles MB, Langedijk JP, Furmanova-Hollenstein P, Chaiwatpongsakorn S, Costello HM, Kwanten L, Vranckx L, Vink P, Jaensch S, Jonckers TH, Koul A, Arnoult E, Peeples ME, Roymans D, McLellan JS
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.
1. Elife - published December 8, 2015
2. He L, Zhang Y, Ma G, Tan P, Li Z, Zang S, Wu X, Jing J, Fang S, Zhou L, Wang Y, Huang Y, Hogan PG, Han G, Zhou Y
Helicobacter pylori Resists the Antimicrobial Activity of Calprotectin via Lipid A Modification and Associated Biofilm Formation.
1. MBio - published December 8, 2015
2. Gaddy JA, Radin JN, Cullen TW, Chazin WJ, Skaar EP, Trent MS, Algood HM
Superdiffusive motion of membrane-targeting C2 domains.
1. Sci Rep - published December 7, 2015
2. Campagnola G, Nepal K, Schroder BW, Peersen OB, Krapf D
Rapid RNA-ligand interaction analysis through high-information content conformational and stability landscapes.
1. Nat Commun - published December 7, 2015
2. Baird NJ, Inglese J, Ferré-D'Amaré AR
Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.
1. Antimicrob. Agents Chemother. - published December 7, 2015
2. Hoekstra WJ, Hargrove TY, Wawrzak Z, da Gama Jaen Batista D, da Silva CF, Nefertiti AS, Rachakonda G, Schotzinger RJ, Villalta F, Soeiro Mde N, Lepesheva GI
The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments.
1. J. Biol. Chem. - published December 4, 2015
2. Vajjhala PR, Lu A, Brown DL, Pang SW, Sagulenko V, Sester DP, Cridland SO, Hill JM, Schroder K, Stow JL, Wu H, Stacey KJ
Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA(3)(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.
1. J Mol Biol - published December 4, 2015
2. Finer-Moore J, Czudnochowski N, O'Connell JD 3rd, Wang AL, Stroud RM
Conformational Transitions that Enable Histidine Kinase Autophosphorylation and Receptor Array Integration.
1. J. Mol. Biol. - published December 4, 2015
2. Greenswag AR, Muok A, Li X, Crane BR
Gln40 deamidation blocks structural reconfiguration and activation of SCF ubiquitin ligase complex by Nedd8.
1. Nat Commun - published December 4, 2015
2. Yu C, Mao H, Novitsky EJ, Tang X, Rychnovsky SD, Zheng N, Huang L
An Evolution-Based Screen for Genetic Differentiation between Anopheles Sister Taxa Enriches for Detection of Functional Immune Factors.
1. PLoS Pathog. - published December 4, 2015
2. Mitri C, Bischoff E, Takashima E, Williams M, Eiglmeier K, Pain A, Guelbeogo WM, Gneme A, Brito-Fravallo E, Holm I, Lavazec C, Sagnon N, Baxter RH, Riehle MM, Vernick KD
Editorial overview: Protein-protein interactions.
1. Curr. Opin. Struct. Biol. - published December 4, 2015
2. Bonvin AM, Keskin Ö
A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies.
1. J. Virol. - published December 4, 2015
2. Ding S, Veillette M, Coutu M, Prévost J, Scharf L, Bjorkman PJ, Ferrari G, Robinson JE, Stürzel C, Hahn BH, Sauter D, Kirchhoff F, Lewis GK, Pazgier M, Finzi A
Pinpointing RNA-Protein Cross-Links with Site-Specific Stable Isotope-Labeled Oligonucleotides.
1. J. Am. Chem. Soc. - published December 3, 2015
2. Lelyveld VS, Björkbom A, Ransey EM, Sliz P, Szostak JW
Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.
1. PLoS One - published December 3, 2015
2. Zhou Y, Williams J, Smallwood PM, Nathans J
Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of Brivudine.
1. PLoS ONE - published December 3, 2015
2. Hew K, Dahlroth SL, Veerappan S, Pan LX, Cornvik T, Nordlund P
ELEVATED INTRAOCULAR PRESSURE FOLLOWING PARS PLANA VITRECTOMY DUE TO TRAPPED GAS IN THE POSTERIOR CHAMBER.
1. Retin Cases Brief Rep - published December 3, 2015
2. Chin EK, Almeida DR, Strohbehn AL, Mahajan VB, Russell SR, Folk JC
Asymmetric ring structure of Vps4 required for ESCRT-III disassembly.
1. Nat Commun - published December 3, 2015
2. Caillat C, Macheboeuf P, Wu Y, McCarthy AA, Boeri-Erba E, Effantin G, Göttlinger HG, Weissenhorn W, Renesto P
An integrative somatic mutation analysis to identify pathways linked with survival outcomes across 19 cancer types.
1. Bioinformatics - published December 3, 2015
2. Park S, Kim SJ, Yu D, Peña-Llopis S, Gao J, Park JS, Chen B, Norris J, Wang X, Chen M, Kim M, Yong J, Wardak Z, Choe K, Story M, Starr T, Cheong JH, Hwang TH
Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome.
1. Mol. Cell - published December 3, 2015
2. Floor SN, Doudna JA
DyNAvectors: dynamic constitutional vectors for adaptive DNA transfection.
1. Chem Commun (Camb) - published December 2, 2015
2. Clima L, Peptanariu D, Pinteala M, Salic A, Barboiu M
Structural Aspects of Bacterial Outer Membrane Protein Assembly.
1. Adv Exp Med Biol - published December 2, 2015
2. Calmettes C, Judd A, Moraes TF
Calorimetry of Nucleic Acids.
1. Curr Protoc Nucleic Acid Chem - published December 2, 2015
2. Rozners E, Pilch DS, Egli M
Inositol phosphate kinase 2 is required for imaginal disc development in Drosophila.
1. Proc Natl Acad Sci U S A - published December 2, 2015
2. Seeds AM, Tsui MM, Sunu C, Spana EP, York JD
GMPPB-Associated Dystroglycanopathy: Emerging Common Variants with Phenotype Correlation.
1. Hum Mutat - published December 1, 2015
2. Jensen BS, Willer T, Saade DN, Cox MO, Mozaffar T, Scavina M, Stefans VA, Winder TL, Campbell KP, Moore SA, Mathews KD
Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68.
1. Antimicrob Agents Chemother - published December 1, 2015
2. Sun L, Meijer A, Froeyen M, Zhang L, Thibaut HJ, Baggen J, George S, Vernachio J, van Kuppeveld FJ, Leyssen P, Hilgenfeld R, Neyts J, Delang L
An electron microscopy journey in the study of microtubule structure and dynamics.
1. Protein Sci - published December 1, 2015
2. Nogales E
A strategy for dissecting the architectures of native macromolecular assemblies.
1. Nat Methods - published December 1, 2015
2. Shi Y, Pellarin R, Fridy PC, Fernandez-Martinez J, Thompson MK, Li Y, Wang QJ, Sali A, Rout MP, Chait BT
A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing.
1. EMBO Rep - published December 1, 2015
2. Peschek J, Acosta-Alvear D, Mendez AS, Walter P
Dynamics of co-translational protein targeting.
1. Curr Opin Chem Biol - published December 1, 2015
2. Elvekrog MM, Walter P
Synergistic antiviral activity of gemcitabine and ribavirin against enteroviruses.
1. Antiviral Res - published December 1, 2015
2. Kang H, Kim C, Kim DE, Song JH, Choi M, Choi K, Kang M, Lee K, Kim HS, Shin JS, Kim J, Han SB, Lee MY, Lee SU, Lee CK, Kim M, Ko HJ, van Kuppeveld FJ, Cho S
Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase.
1. Structure - published December 1, 2015
2. Khare D, Hale WA, Tripathi A, Gu L, Sherman DH, Gerwick WH, Håkansson K, Smith JL
Small Molecules Take A Big Step Against Clostridium difficile.
1. Trends Microbiol - published December 1, 2015
2. Beilhartz GL, Tam J, Melnyk RA
First International Workshopson Provocative Questions (PQ) in Cancer Research, October-November 2014, New Delhi, Bengaluru, and Thiruvananthapuram, India.
1. J Cancer Policy - published December 1, 2015
2. Rajaraman P, Dey B, Majumder PP, Mayor S, Pillai MR, Ramaswamy S, Shaha C, Johnson M, Sivaram S, Trimble EL, Harlow EE, VijayRaghavan K
The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.
1. RNA - published December 1, 2015
2. Davidovich C, Cech TR
ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy.
1. Nat Commun - published December 1, 2015
2. Albright RA, Stabach P, Cao W, Kavanagh D, Mullen I, Braddock AA, Covo MS, Tehan M, Yang G, Cheng Z, Bouchard K, Yu ZX, Thorn S, Wang X, Folta-Stogniew EJ, Negrete A, Sinusas AJ, Shiloach J, Zubal G, Madri JA, De La Cruz EM, Braddock DT
Architecture of the human XPC DNA repair and stem cell coactivator complex.
1. Proc Natl Acad Sci U S A - published December 1, 2015
2. Zhang ET, He Y, Grob P, Fong YW, Nogales E, Tjian R
Src defines a new pool of EGFR substrates.
1. Nat Struct Mol Biol - published December 1, 2015
2. Michael N, Jura N
Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
1. Cell Rep - published December 1, 2015
2. Ren A, Xue Y, Peselis A, Serganov A, Al-Hashimi HM, Patel DJ
Nudix hydrolases degrade protein-conjugated ADP-ribose.
1. Sci Rep - published December 1, 2015
2. Daniels CM, Thirawatananond P, Ong SE, Gabelli SB, Leung AK
Coordinated and Compartmentalized Neuromodulation Shapes Sensory Processing in Drosophila.
1. Cell - published December 1, 2015
2. Cohn R, Morantte I, Ruta V