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116 Member Publications for June 2014

Photoreactive stapled peptides to identify and characterize BCL-2 family interaction sites by mass spectrometry.
1. Methods Enzymol - published June 30, 2014
2. Lee S, Braun CR, Bird GH, Walensky LD
Caspase enzymology and activation mechanisms.
1. Methods Enzymol - published June 30, 2014
2. Mace PD, Riedl SJ, Salvesen GS
The structural biology of BH3-only proteins.
1. Methods Enzymol - published June 30, 2014
2. Kvansakul M, Hinds MG
Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens.
1. Nucleic Acids Res. - published June 29, 2014
2. Zhong R, Kim J, Kim HS, Kim M, Lum L, Levine B, Xiao G, White MA, Xie Y
Host competence and helicase activity differences exhibited by West Nile viral variants expressing NS3-249 amino acid polymorphisms.
1. PLoS One - published June 28, 2014
2. Langevin SA, Bowen RA, Reisen WK, Andrade CC, Ramey WN, Maharaj PD, Anishchenko M, Kenney JL, Duggal NK, Romo H, Bera AK, Sanders TA, Bosco-Lauth A, Smith JL, Kuhn R, Brault AC
Traditional formula, modern application: chinese medicine formula sini tang improves early ventricular remodeling and cardiac function after myocardial infarction in rats.
1. Evid Based Complement Alternat Med - published June 28, 2014
2. Liu J, Peter K, Shi D, Zhang L, Dong G, Zhang D, Breiteneder H, Jakowitsch J, Ma Y
Error-prone replication bypass of the primary aflatoxin B1 DNA adduct, AFB1-N7-Gua.
1. J. Biol. Chem. - published June 27, 2014
2. Lin YC, Li L, Makarova AV, Burgers PM, Stone MP, Lloyd RS
The linker region of NS3 plays a critical role in the replication and infectivity of hepatitis C virus.
1. J. Virol. - published June 27, 2014
2. Kohlway A, Pirakitikulr N, Ding SC, Yang F, Luo D, Lindenbach BD, Pyle AM
Prolonged expression of an anti-HIV-1 gp120 minibody to the female rhesus macaque lower genital tract by AAV gene transfer.
1. Gene Ther. - published June 27, 2014
2. Abdel-Motal UM, Harbison C, Han T, Pudney J, Anderson DJ, Zhu Q, Westmoreland S, Marasco WA
Patient-reported outcome measures for asthma: a systematic review.
1. NPJ Prim Care Respir Med - published June 27, 2014
2. Worth A, Hammersley V, Knibb R, Flokstra-de-Blok B, DunnGalvin A, Walker S, Dubois AE, Sheikh A
Nonhuman genetics. Genomic basis for the convergent evolution of electric organs.
1. Science - published June 27, 2014
2. Gallant JR, Traeger LL, Volkening JD, Moffett H, Chen PH, Novina CD, Phillips GN, Anand R, Wells GB, Pinch M, Güth R, Unguez GA, Albert JS, Zakon HH, Samanta MP, Sussman MR
Synthesis of rigidified eIF4E/eIF4G inhibitor-1 (4EGI-1) mimetic and their in vitro characterization as inhibitors of protein-protein interaction.
1. J. Med. Chem. - published June 26, 2014
2. Mahalingam P, Takrouri K, Chen T, Sahoo R, Papadopoulos E, Chen L, Wagner G, Aktas BH, Halperin JA, Chorev M
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
1. Nature - published June 26, 2014
2. Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, Kibbey RG, Shulman GI
High-resolution views of TRPV1 and their implications for the TRP channel superfamily.
1. Handb Exp Pharmacol - published June 26, 2014
2. Hellmich UA, Gaudet R
Structural biology of TRP channels.
1. Handb Exp Pharmacol - published June 26, 2014
2. Hellmich UA, Gaudet R
Structural rearrangements of a polyketide synthase module during its catalytic cycle.
1. Nature - published June 26, 2014
2. Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G
Structure of a modular polyketide synthase.
1. Nature - published June 26, 2014
2. Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G
Synergy of streptogramin antibiotics occurs independently of their effects on translation.
1. Antimicrob. Agents Chemother. - published June 25, 2014
2. Noeske J, Huang J, Olivier NB, Giacobbe RA, Zambrowski M, Cate JH
Chemosensory regulation of a HEAT-repeat protein couples aggregation and sporulation in Myxococcus xanthus.
1. J. Bacteriol. - published June 25, 2014
2. Darnell CL, Wilson JM, Tiwari N, Fuentes EJ, Kirby JR
Endoplasmic Reticulum Stress Sensor Protein Kinase R-Like Endoplasmic Reticulum Kinase (PERK) Protects Against Pressure Overload-Induced Heart Failure and Lung Remodeling.
1. Hypertension - published June 25, 2014
2. Liu X, Kwak D, Lu Z, Xu X, Fassett J, Wang H, Wei Y, Cavener DR, Hu X, Hall J, Bache RJ, Chen Y
Probing the paramyxovirus fusion (F) protein-refolding event from pre- to postfusion by oxidative footprinting.
1. Proc. Natl. Acad. Sci. U.S.A. - published June 24, 2014
2. Poor TA, Jones LM, Sood A, Leser GP, Plasencia MD, Rempel DL, Jardetzky TS, Woods RJ, Gross ML, Lamb RA
Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 • Nup98).
1. Proc. Natl. Acad. Sci. U.S.A. - published June 24, 2014
2. Quan B, Seo HS, Blobel G, Ren Y
Tissue-specific expressed antibody variable gene repertoires.
1. PLoS One - published June 24, 2014
2. Briney BS, Willis JR, Finn JA, McKinney BA, Crowe JE Jr
Notch inhibition allows oncogene-independent generation of iPS cells.
1. Nat. Chem. Biol. - published June 23, 2014
2. Ichida JK, T C W J, Williams LA, Carter AC, Shi Y, Moura MT, Ziller M, Singh S, Amabile G, Bock C, Umezawa A, Rubin LL, Bradner JE, Akutsu H, Meissner A, Eggan K
A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
1. Nat. Chem. Biol. - published June 23, 2014
2. Huang H, Suslov NB, Li NS, Shelke SA, Evans ME, Koldobskaya Y, Rice PA, Piccirilli JA
A Newly Discovered TSHR Variant (L665F) Associated With Nonautoimmune Hyperthyroidism in an Austrian Family Induces Constitutive TSHR Activation by Steric Repulsion Between TM1 and TM7.
1. J. Clin. Endocrinol. Metab. - published June 21, 2014
2. Jaeschke H, Schaarschmidt J, Eszlinger M, Huth S, Puttinger R, Rittinger O, Meiler J, Paschke R
Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation.
1. PLoS ONE - published June 21, 2014
2. Luo R, Jeong SJ, Yang A, Wen M, Saslowsky DE, Lencer WI, Araç D, Piao X
Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery.
1. Nat Chem - published June 21, 2014
2. Fischer M, Coleman RG, Fraser JS, Shoichet BK
Multimeric assembly of host-pathogen adhesion complexes involved in apicomplexan invasion.
1. PLoS Pathog. - published June 20, 2014
2. Paing MM, Tolia NH
Patient aberrant drug taking behaviors in a large family medicine residency program: a retrospective chart review of screening practices, incidence, and predictors.
1. J Opioid Manag - published June 20, 2014
2. Lewis M, Herndon CM, Chibnall JT
Structural features of the Nogo receptor signaling complexes at the neuron/myelin interface.
1. Neurosci. Res. - published June 20, 2014
2. Saha N, Kolev M, Nikolov DB
Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.
1. Oncogene - published June 19, 2014
2. Cipriano R, Bryson BL, Miskimen KL, Bartel CA, Hernandez-Sanchez W, Bruntz RC, Scott SA, Lindsley CW, Brown HA, Jackson MW
Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
1. Nature - published June 19, 2014
2. Sasaki E, Zhang X, Sun HG, Lu MY, Liu TL, Ou A, Li JY, Chen YH, Ealick SE, Liu HW
Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.
1. Mol. Cell - published June 19, 2014
2. Yasui N, Findlay GM, Gish GD, Hsiung MS, Huang J, Tucholska M, Taylor L, Smith L, Boldridge WC, Koide A, Pawson T, Koide S
Finding of widespread viral and bacterial revolution dsDNA translocation motors distinct from rotation motors by channel chirality and size.
1. Cell Biosci - published June 19, 2014
2. De-Donatis GM, Zhao Z, Wang S, Huang LP, Schwartz C, Tsodikov OV, Zhang H, Haque F, Guo P
Solution structure of the 2A protease from a common cold agent, human rhinovirus C2, strain W12.
1. PLoS ONE - published June 18, 2014
2. Lee W, Watters KE, Troupis AT, Reinen NM, Suchy FP, Moyer KL, Frederick RO, Tonelli M, Aceti DJ, Palmenberg AC, Markley JL
Obesity and cancer--mechanisms underlying tumour progression and recurrence.
1. Nat Rev Endocrinol - published June 18, 2014
2. Park J, Morley TS, Kim M, Clegg DJ, Scherer PE
In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.
1. Proc. Natl. Acad. Sci. U.S.A. - published June 17, 2014
2. Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD
Activation of SOX2 expression by BRD4-NUT oncogenic fusion drives neoplastic transformation in NUT midline carcinoma.
1. Cancer Res. - published June 15, 2014
2. Wang R, Liu W, Helfer CM, Bradner JE, Hornick JL, Janicki SM, French CA, You J
Synthesis and SAR of substituted pyrazolo[1,5-a]quinazolines as dual mGlu(2)/mGlu(3) NAMs.
1. Bioorg. Med. Chem. Lett. - published June 15, 2014
2. Wenthur CJ, Morrison RD, Daniels JS, Conn PJ, Lindsley CW
Effect of CDR3 sequences and distal V gene residues in regulating TCR-MHC contacts and ligand specificity.
1. J. Immunol. - published June 15, 2014
2. Stadinski BD, Trenh P, Duke B, Huseby PG, Li G, Stern LJ, Huseby ES
(1)H, (13)C, and (15)N backbone and sidechain chemical shift assignments for the HEAT2 domain of human eIF4GI.
1. Biomol NMR Assign - published June 15, 2014
2. Edmonds KA, Wagner G
How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
1. Genes Dev. - published June 15, 2014
2. Doamekpor SK, Sanchez AM, Schwer B, Shuman S, Lima CD
Structural basis for catalysis in a CDP-alcohol phosphotransferase.
1. Nat Commun - published June 14, 2014
2. Sciara G, Clarke OB, Tomasek D, Kloss B, Tabuso S, Byfield R, Cohn R, Banerjee S, Rajashankar KR, Slavkovic V, Graziano JH, Shapiro L, Mancia F
NMR approaches for structural analysis of multidomain proteins and complexes in solution.
1. Prog Nucl Magn Reson Spectrosc - published June 14, 2014
2. Göbl C, Madl T, Simon B, Sattler M
Architecture of the nitric-oxide synthase holoenzyme reveals large conformational changes and a calmodulin-driven release of the FMN domain.
1. J. Biol. Chem. - published June 13, 2014
2. Yokom AL, Morishima Y, Lau M, Su M, Glukhova A, Osawa Y, Southworth DR
Kinetics, structure, and mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine bypass by human DNA polymerase η.
1. J. Biol. Chem. - published June 13, 2014
2. Patra A, Nagy LD, Zhang Q, Su Y, Müller L, Guengerich FP, Egli M
Structure of the small Dictyostelium discoideum myosin light chain MlcB provides insights into MyoB IQ motif recognition.
1. J. Biol. Chem. - published June 13, 2014
2. Liburd J, Chitayat S, Crawley SW, Munro K, Miller E, Denis CM, Spencer HL, Côté GP, Smith SP
Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
1. Science - published June 13, 2014
2. Xu K, Wu Z, Renier N, Antipenko A, Tzvetkova-Robev D, Xu Y, Minchenko M, Nardi-Dei V, Rajashankar KR, Himanen J, Tessier-Lavigne M, Nikolov DB
The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability.
1. PLoS Genet. - published June 13, 2014
2. Fattah FJ, Hara K, Fattah KR, Yang C, Wu N, Warrington R, Chen DJ, Zhou P, Boothman DA, Yu H
A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.
1. J. Mol. Biol. - published June 12, 2014
2. Shinsky SA, Hu M, Vought VE, Ng SB, Bamshad MJ, Shendure J, Cosgrove MS
Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W.
1. J. Mol. Biol. - published June 12, 2014
2. Schilling J, Schöppe J, Sauer E, Plückthun A
The CD3 conformational change in the γδ T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing.
1. Cell Rep - published June 12, 2014
2. Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WW
Membrane deformation and scission by the HSV-1 nuclear egress complex.
1. Nat Commun - published June 12, 2014
2. Bigalke JM, Heuser T, Nicastro D, Heldwein EE
Validity of ligand efficiency metrics.
1. ACS Med Chem Lett - published June 12, 2014
2. Murray CW, Erlanson DA, Hopkins AL, Keserü GM, Leeson PD, Rees DC, Reynolds CH, Richmond NJ
Contrast formation in Kelvin probe force microscopy of single π-conjugated molecules.
1. Nano Lett. - published June 11, 2014
2. Schuler B, Liu SX, Geng Y, Decurtins S, Meyer G, Gross L
Structure of the branched intermediate in protein splicing.
1. Proc. Natl. Acad. Sci. U.S.A. - published June 10, 2014
2. Liu Z, Frutos S, Bick MJ, Vila-Perelló M, Debelouchina GT, Darst SA, Muir TW
Key interactions for clathrin coat stability.
1. Structure - published June 10, 2014
2. Böcking T, Aguet F, Rapoport I, Banzhaf M, Yu A, Zeeh JC, Kirchhausen T
PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.
1. Eur J Med Chem - published June 10, 2014
2. Perrone MG, Malerba P, Uddin MJ, Vitale P, Panella A, Crews BC, Daniel CK, Ghebreselasie K, Nickels M, Tantawy MN, Manning HC, Marnett LJ, Scilimati A
Crystal cryocooling distorts conformational heterogeneity in a model michaelis complex of DHFR.
1. Structure - published June 10, 2014
2. Keedy DA, van den Bedem H, Sivak DA, Petsko GA, Ringe D, Wilson MA, Fraser JS
An evolving arsenal: viral RNA detection by RIG-I-like receptors.
1. Curr. Opin. Microbiol. - published June 10, 2014
2. Fitzgerald ME, Rawling DC, Vela A, Pyle AM
Interactive features of proteins composing eukaryotic circadian clocks.
1. Annu Rev Biochem - published June 7, 2014
2. Crane BR, Young MW
Commentary on Lee et al. (2014): Betel-quid-when East encounters West.
1. Addiction - published June 7, 2014
2. Ho MC
Muscarinic acetylcholine receptors: novel opportunities for drug development.
1. Nat Rev Drug Discov - published June 7, 2014
2. Kruse AC, Kobilka BK, Gautam D, Sexton PM, Christopoulos A, Wess J
Fluorescence resonance energy transfer studies of DNA polymerase β: the critical role of fingers domain movements and a novel non-covalent step during nucleotide selection.
1. J. Biol. Chem. - published June 6, 2014
2. Towle-Weicksel JB, Dalal S, Sohl CD, Doublié S, Anderson KS, Sweasy JB
Neonatal and maternal outcomes with prolonged second stage of labor.
1. Obstet Gynecol - published June 6, 2014
2. Laughon SK, Berghella V, Reddy UM, Sundaram R, Lu Z, Hoffman MK
The Haemophilus ducreyi LspA1 protein inhibits phagocytosis by using a new mechanism involving activation of C-terminal Src kinase.
1. MBio - published June 6, 2014
2. Dodd DA, Worth RG, Rosen MK, Grinstein S, van Oers NS, Hansen EJ
Adolescent seasonal allergic rhinitis and the impact of health-care professional training: cluster randomised controlled trial of a complex intervention in primary care.
1. NPJ Prim Care Respir Med - published June 6, 2014
2. Hammersley VS, Elton RA, Walker S, Hansen CH, Sheikh A
A mutually assured destruction mechanism attenuates light signaling in Arabidopsis.
1. Science - published June 6, 2014
2. Ni W, Xu SL, Tepperman JM, Stanley DJ, Maltby DA, Gross JD, Burlingame AL, Wang ZY, Quail PH
Accurate design of co-assembling multi-component protein nanomaterials.
1. Nature - published June 5, 2014
2. King NP, Bale JB, Sheffler W, McNamara DE, Gonen S, Gonen T, Yeates TO, Baker D
Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.
1. Mol. Cancer - published June 5, 2014
2. Cho J, Bass AJ, Lawrence MS, Cibulskis K, Cho A, Lee SN, Yamauchi M, Wagle N, Pochanard P, Kim N, Park AK, Won J, Hur HS, Greulich H, Ogino S, Sougnez C, Voet D, Tabernero J, Jimenez J, Baselga J, Gabriel SB, Lander ES, Getz G, Eck MJ, Park WY, Meyerson M
Development and applications of CRISPR-Cas9 for genome engineering.
1. Cell - published June 5, 2014
2. Hsu PD, Lander ES, Zhang F
A "push and slide" mechanism allows sequence-insensitive translocation of secretory proteins by the SecA ATPase.
1. Cell - published June 5, 2014
2. Bauer BW, Shemesh T, Chen Y, Rapoport TA
Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.
1. Cell - published June 5, 2014
2. Szyk A, Deaconescu AM, Spector J, Goodman B, Valenstein ML, Ziolkowska NE, Kormendi V, Grigorieff N, Roll-Mecak A
Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes.
1. Cell - published June 5, 2014
2. Walch M, Dotiwala F, Mulik S, Thiery J, Kirchhausen T, Clayberger C, Krensky AM, Martinvalet D, Lieberman J
Role of IscX in iron-sulfur cluster biogenesis in Escherichia coli.
1. J. Am. Chem. Soc. - published June 4, 2014
2. Kim JH, Bothe JR, Frederick RO, Holder JC, Markley JL
Ca2+-stabilized adhesin helps an Antarctic bacterium reach out and bind ice.
1. Biosci. Rep. - published June 4, 2014
2. Vance TD, Olijve LL, Campbell RL, Voets IK, Davies PL, Guo S
Dihydroisoxazole inhibitors of Anopheles gambiae seminal transglutaminase AgTG3.
1. Malar. J. - published June 4, 2014
2. Le BV, Klöck C, Schatz A, Nguyen JB, Kakani EG, Catteruccia F, Khosla C, Baxter RH
Cancer immunotherapeutics: evolution of monoclonal antibodies to peptide immunogens.
1. Monoclon Antib Immunodiagn Immunother - published June 4, 2014
2. Murali R, Kieber-Emmons T
The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins.
1. Proc Natl Acad Sci U S A - published June 3, 2014
2. Okreglak V, Walter P
The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
1. Proc. Natl. Acad. Sci. U.S.A. - published June 3, 2014
2. Feige MJ, Gräwert MA, Marcinowski M, Hennig J, Behnke J, Ausländer D, Herold EM, Peschek J, Castro CD, Flajnik M, Hendershot LM, Sattler M, Groll M, Buchner J
The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bacterium.
1. Proc. Natl. Acad. Sci. U.S.A. - published June 3, 2014
2. Santos JA, Alonso-García N, Macedo-Ribeiro S, Pereira PJ
Microarray-based screening of heat shock protein inhibitors.
1. J Biotechnol - published June 2, 2014
2. Schax E, Walter JG, Märzhäuser H, Stahl F, Scheper T, Agard DA, Eichner S, Kirschning A, Zeilinger C
Correcting direct effects of ethanol on translation and transcription machinery confers ethanol tolerance in bacteria.
1. Proc Natl Acad Sci U S A - published June 2, 2014
2. Haft RJ, Keating DH, Schwaegler T, Schwalbach MS, Vinokur J, Tremaine M, Peters JM, Kotlajich MV, Pohlmann EL, Ong IM, Grass JA, Kiley PJ, Landick R
2D IR spectroscopy reveals the role of water in the binding of channel-blocking drugs to the influenza M2 channel.
1. J Chem Phys - published June 2, 2014
2. Ghosh A, Wang J, Moroz YS, Korendovych IV, Zanni M, DeGrado WF, Gai F, Hochstrasser RM
Flat mount imaging of mouse skin and its application to the analysis of hair follicle patterning and sensory axon morphology.
1. J Vis Exp - published June 2, 2014
2. Chang H, Wang Y, Wu H, Nathans J
Sex differences in corticotropin-releasing factor receptor-1 action within the dorsal raphe nucleus in stress responsivity.
1. Biol. Psychiatry - published June 1, 2014
2. Howerton AR, Roland AV, Fluharty JM, Marshall A, Chen A, Daniels D, Beck SG, Bale TL
Delirium and coma evaluated in mechanically ventilated patients in the intensive care unit in Japan: a multi-institutional prospective observational study.
1. J Crit Care - published June 1, 2014
2. Tsuruta R, Oda Y, Shintani A, Nunomiya S, Hashimoto S, Nakagawa T, Oida Y, Miyazaki D, Yabe S, Japanese Epidemiology of Delirium in ICUs (JEDI) Study Investigators.
New molecular engineering approaches for crystallographic studies of large RNAs.
1. Curr Opin Struct Biol - published June 1, 2014
2. Zhang J, Ferré-D'Amaré AR
Expression, purification and characterization of a functional carbohydrate-binding module from Streptomyces sp. SirexAA-E.
1. Protein Expr Purif - published June 1, 2014
2. Lim S, Chundawat SP, Fox BG
Identification of mTORC2 as a necessary component of HRG/ErbB2-dependent cellular transformation.
1. Mol Cancer Res - published June 1, 2014
2. Lin MC, Rojas KS, Cerione RA, Wilson KF
Sec16 determines the size and functioning of the Golgi in the protist parasite, Trypanosoma brucei.
1. Traffic - published June 1, 2014
2. Sealey-Cardona M, Schmidt K, Demmel L, Hirschmugl T, Gesell T, Dong G, Warren G
The molecular architecture of QdtA, a sugar 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum.
1. Protein Sci - published June 1, 2014
2. Thoden JB, Holden HM
Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells.
1. J Allergy Clin Immunol - published June 1, 2014
2. Eggel A, Baravalle G, Hobi G, Kim B, Buschor P, Forrer P, Shin JS, Vogel M, Stadler BM, Dahinden CA, Jardetzky TS
The dynamic duo: combining NMR and small angle scattering in structural biology.
1. Protein Sci - published June 1, 2014
2. Hennig J, Sattler M
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain.
1. Mol Cell Biol - published June 1, 2014
2. Piccoli G, Onofri F, Cirnaru MD, Kaiser CJ, Jagtap P, Kastenmüller A, Pischedda F, Marte A, von Zweydorf F, Vogt A, Giesert F, Pan L, Antonucci F, Kiel C, Zhang M, Weinkauf S, Sattler M, Sala C, Matteoli M, Ueffing M, Gloeckner CJ
Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation.
1. Nucleic Acids Res - published June 1, 2014
2. Moursy A, Allain FH, Cléry A
CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies.
1. J Virol - published June 1, 2014
2. Madani N, Princiotto AM, Schön A, LaLonde J, Feng Y, Freire E, Park J, Courter JR, Jones DM, Robinson J, Liao HX, Moody MA, Permar S, Haynes B, Smith AB 3rd, Wyatt R, Sodroski J
Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.
1. RNA - published June 1, 2014
2. Egan ED, Braun CR, Gygi SP, Moazed D
Effects of 6-hydroxydopamine exposure on motor activity and biochemical expression in zebrafish (Danio rerio) larvae.
1. Zebrafish - published June 1, 2014
2. Feng CW, Wen ZH, Huang SY, Hung HC, Chen CH, Yang SN, Chen NF, Wang HM, Hsiao CD, Chen WF
Elucidating the mechanism of substrate recognition by the bacterial Hsp90 molecular chaperone.
1. J Mol Biol - published June 1, 2014
2. Street TO, Zeng X, Pellarin R, Bonomi M, Sali A, Kelly MJ, Chu F, Agard DA
A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein.
1. Mol Cancer Ther - published June 1, 2014
2. Pop MS, Stransky N, Garvie CW, Theurillat JP, Hartman EC, Lewis TA, Zhong C, Culyba EK, Lin F, Daniels DS, Pagliarini R, Ronco L, Koehler AN, Garraway LA
The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs.
1. RNA - published June 1, 2014
2. Cora E, Pandey RR, Xiol J, Taylor J, Sachidanandam R, McCarthy AA, Pillai RS
Discovery of BRD4 bromodomain inhibitors by fragment-based high-throughput docking.
1. Bioorg. Med. Chem. Lett. - published June 1, 2014
2. Zhao H, Gartenmann L, Dong J, Spiliotopoulos D, Caflisch A
Serum- and glucocorticoid-induced protein kinase 1 (SGK1) increases the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells by phosphorylating Shank2E protein.
1. J Biol Chem - published June 1, 2014
2. Koeppen K, Coutermarsh BA, Madden DR, Stanton BA
RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1.
1. Mol Cell - published June 1, 2014
2. Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T, Meinhart A
A suite of software for processing MicroED data of extremely small protein crystals.
1. J Appl Crystallogr - published June 1, 2014
2. Iadanza MG, Gonen T
Using a commodity high-definition television for collaborative structural biology.
1. J Appl Crystallogr - published June 1, 2014
2. Yennamalli R, Arangarasan R, Bryden A, Gleicher M, Phillips GN
Editorial overview: Cell nucleus: the nucleus: a dynamic organelle.
1. Curr Opin Cell Biol - published June 1, 2014
2. Rout MP, Karpen GH
An Arp2/3 nucleated F-actin shell fragments nuclear membranes at nuclear envelope breakdown in starfish oocytes.
1. Curr Biol - published June 1, 2014
2. Mori M, Somogyi K, Kondo H, Monnier N, Falk HJ, Machado P, Bathe M, Nédélec F, Lénárt P
RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts.
1. Cell - published June 1, 2014
2. Xiol J, Spinelli P, Laussmann MA, Homolka D, Yang Z, Cora E, Couté Y, Conn S, Kadlec J, Sachidanandam R, Kaksonen M, Cusack S, Ephrussi A, Pillai RS
Structure of BamA, an essential factor in outer membrane protein biogenesis.
1. Acta Crystallogr D Biol Crystallogr - published June 1, 2014
2. Albrecht R, Schütz M, Oberhettinger P, Faulstich M, Bermejo I, Rudel T, Diederichs K, Zeth K
Selective targeting of TGF-β activation to treat fibroinflammatory airway disease.
1. Sci Transl Med - published June 1, 2014
2. Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL
Glucocorticoid receptor function regulated by coordinated action of the Hsp90 and Hsp70 chaperone cycles.
1. Cell - published June 1, 2014
2. Kirschke E, Goswami D, Southworth D, Griffin PR, Agard DA
Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules.
1. Chem Sci - published June 1, 2014
2. Parker CG, Dahlgren MK, Tao RN, Li DT, Douglass EF Jr, Shoda T, Jawanda N, Spasov KA, Lee S, Zhou N, Domaoal RA, Sutton RE, Anderson KS, Jorgensen WL, Krystal M, Spiegel DA
Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production.
1. Russ J Genet - published June 1, 2014
2. Mutenko H, Makitrinskyy R, Tsypik O, Walker S, Ostash B, Fedorenko V