Member Publications

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66 Member Publications for August 2012

Structural biology of replication initiation factor Mcm10.
1. Subcell Biochem - published August 25, 2012
2. Du W, Stauffer ME, Eichman BF
Toward a structural understanding of Clostridium difficile toxins A and B.
1. Front Cell Infect Microbiol - published August 25, 2012
2. Pruitt RN, Lacy DB
Quantifying chromatin-associated interactions: the HI-FI system.
1. Methods Enzymol - published August 23, 2012
2. Winkler DD, Luger K, Hieb AR
Structures of Pup ligase PafA and depupylase Dop from the prokaryotic ubiquitin-like modification pathway.
1. Nat Commun - published August 23, 2012
2. Özcelik D, Barandun J, Schmitz N, Sutter M, Guth E, Damberger FF, Allain FH, Ban N, Weber-Ban E
The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors.
1. PLoS Pathog - published August 23, 2012
2. Romano KP, Ali A, Aydin C, Soumana D, Ozen A, Deveau LM, Silver C, Cao H, Newton A, Petropoulos CJ, Huang W, Schiffer CA
Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence.
1. PLoS Pathog - published August 23, 2012
2. Yuan P, Paterson RG, Leser GP, Lamb RA, Jardetzky TS
R(h)oads to microvesicles.
1. Small GTPases - published August 22, 2012
2. Antonyak MA, Wilson KF, Cerione RA
Structural analysis of specific metal chelating inhibitor binding to the endonuclease domain of influenza pH1N1 (2009) polymerase.
1. PLoS Pathog - published August 10, 2012
2. Kowalinski E, Zubieta C, Wolkerstorfer A, Szolar OH, Ruigrok RW, Cusack S
Controlled delivery of bioactive molecules into live cells using the bacterial mechanosensitive channel MscL.
1. Nat Commun - published August 9, 2012
2. Doerner JF, Febvay S, Clapham DE
Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.
1. Structure - published August 8, 2012
2. Zimanyi CM, Ando N, Brignole EJ, Asturias FJ, Stubbe J, Drennan CL
Small terminase couples viral DNA binding to genome-packaging ATPase activity.
1. Structure - published August 8, 2012
2. Roy A, Bhardwaj A, Datta P, Lander GC, Cingolani G
Mechanism of Cd2+ coordination during slow inactivation in potassium channels.
1. Structure - published August 8, 2012
2. Raghuraman H, Cordero-Morales JF, Jogini V, Pan AC, Kollewe A, Roux B, Perozo E
A role for intersubunit interactions in maintaining SAGA deubiquitinating module structure and activity.
1. Structure - published August 8, 2012
2. Samara NL, Ringel AE, Wolberger C
Bayesian approach to MSD-based analysis of particle motion in live cells.
1. Biophys J - published August 8, 2012
2. Monnier N, Guo SM, Mori M, He J, Lénárt P, Bathe M
Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel.
1. Biochemistry - published August 7, 2012
2. Inada H, Procko E, Sotomayor M, Gaudet R
Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion.
1. Proc Natl Acad Sci U S A - published August 7, 2012
2. Liu TY, Bian X, Sun S, Hu X, Klemm RW, Prinz WA, Rapoport TA, Hu J
Molecular motors: a finicky myosin V chooses its own path.
1. Curr Biol - published August 7, 2012
2. Rock RS
A first line of defense against ER stress.
1. J Cell Biol - published August 6, 2012
2. Pincus D, Walter P
Seg1 controls eisosome assembly and shape.
1. J Cell Biol - published August 6, 2012
2. Moreira KE, Schuck S, Schrul B, Fröhlich F, Moseley JB, Walther TC, Walter P
Discrete RNA libraries from pseudo-torsional space.
1. J Mol Biol - published August 3, 2012
2. Humphris-Narayanan E, Pyle AM
Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex.
1. Science - published August 3, 2012
2. Padmanabhan K, Robles MS, Westerling T, Weitz CJ
Plasma membrane reshaping during endocytosis is revealed by time-resolved electron tomography.
1. Cell - published August 3, 2012
2. Kukulski W, Schorb M, Kaksonen M, Briggs JA
The first five seconds in the life of a clathrin-coated pit.
1. Cell - published August 3, 2012
2. Cocucci E, Aguet F, Boulant S, Kirchhausen T
Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
1. Cell Rep - published August 3, 2012
2. Tukachinsky H, Kuzmickas RP, Jao CY, Liu J, Salic A
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.
1. Cell - published August 3, 2012
2. Taipale M, Krykbaeva I, Koeva M, Kayatekin C, Westover KD, Karras GI, Lindquist S
The steric hypothesis for DNA replication and fluorine hydrogen bonding revisited in light of structural data.
1. Acc Chem Res - published August 2, 2012
2. Egli M
Photocontrol of reversible amyloid formation with a minimal-design peptide.
1. J Phys Chem B - published August 2, 2012
2. Waldauer SA, Hassan S, Paoli B, Donaldson PM, Pfister R, Hamm P, Caflisch A, Pellarin R
Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site.
1. Chem Commun (Camb) - published August 2, 2012
2. Obeid S, Busskamp H, Welte W, Diederichs K, Marx A
Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries.
1. Proc Natl Acad Sci U S A - published August 2, 2012
2. Kummer L, Parizek P, Rube P, Millgramm B, Prinz A, Mittl PR, Kaufholz M, Zimmermann B, Herberg FW, Plückthun A
Influenza virus resistance to human neutralizing antibodies.
1. mBio - published August 2, 2012
2. Crowe JE Jr
Structural insights into neuronal K+ channel-calmodulin complexes.
1. Proc Natl Acad Sci U S A - published August 2, 2012
2. Mruk K, Shandilya SM, Blaustein RO, Schiffer CA, Kobertz WR
Structural divergence of paralogous S components from ECF-type ABC transporters.
1. Proc Natl Acad Sci U S A - published August 2, 2012
2. Berntsson RP, ter Beek J, Majsnerowska M, Duurkens RH, Puri P, Poolman B, Slotboom DJ
BCL::EMAS--enantioselective molecular asymmetry descriptor for 3D-QSAR.
1. Molecules - published August 2, 2012
2. Sliwoski G, Lowe EW, Butkiewicz M, Meiler J
Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling.
1. Sci Transl Med - published August 2, 2012
2. Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulciniti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR
A molecular dynamics study of C1r and C1s dimers: implications for the structure of the C1 complex.
1. Proteins - published August 1, 2012
2. Beveridge AJ, Wallis R, Samani NJ
Inhibition of interdomain motion in g-actin by the natural product latrunculin: a molecular dynamics study.
1. Proteins - published August 1, 2012
2. Rennebaum S, Caflisch A
A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
1. Mol Cell Proteomics - published August 1, 2012
2. Sheng Y, Hong JH, Doherty R, Srikumar T, Shloush J, Avvakumov GV, Walker JR, Xue S, Neculai D, Wan JW, Kim SK, Arrowsmith CH, Raught B, Dhe-Paganon S
Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria.
1. Proteins - published August 1, 2012
2. Bitto E, Kim DJ, Bingman CA, Kim HJ, Han BW, Phillips GN Jr
Herpes simplex virus 1 induces de novo phospholipid synthesis.
1. Virology - published August 1, 2012
2. Sutter E, de Oliveira AP, Tobler K, Schraner EM, Sonda S, Kaech A, Lucas MS, Ackermann M, Wild P
Designed ankyrin repeat proteins (DARPins) as novel isoform-specific intracellular inhibitors of c-Jun N-terminal kinases.
1. ACS Chem Biol - published August 1, 2012
2. Parizek P, Kummer L, Rube P, Prinz A, Herberg FW, Plückthun A
Three-dimensional structure of the Epstein-Barr virus capsid.
1. J Gen Virol - published August 1, 2012
2. Germi R, Effantin G, Grossi L, Ruigrok RW, Morand P, Schoehn G
Delineation of the caffeine C-8 oxidation pathway in Pseudomonas sp. strain CBB1 via characterization of a new trimethyluric acid monooxygenase and genes involved in trimethyluric acid metabolism.
1. J Bacteriol - published August 1, 2012
2. Mohanty SK, Yu CL, Das S, Louie TM, Gakhar L, Subramanian M
Membrane requirement for folding of the herpes simplex virus 1 gB cytodomain suggests a unique mechanism of fusion regulation.
1. J Virol - published August 1, 2012
2. Silverman JL, Greene NG, King DS, Heldwein EE
The conserved arginine 380 of Hsp90 is not a catalytic residue, but stabilizes the closed conformation required for ATP hydrolysis.
1. Protein Sci - published August 1, 2012
2. Cunningham CN, Southworth DR, Krukenberg KA, Agard DA
Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection.
1. Infect Immun - published August 1, 2012
2. Kostakioti M, Hadjifrangiskou M, Cusumano CK, Hannan TJ, Janetka JW, Hultgren SJ
Conformational selection in trypsin-like proteases.
1. Curr Opin Struct Biol - published August 1, 2012
2. Pozzi N, Vogt AD, Gohara DW, Di Cera E
Understanding the molecular mechanism of sequence dependent tenofovir removal by HIV-1 reverse transcriptase: differences in primer binding site versus polypurine tract.
1. Antiviral Res - published August 1, 2012
2. Iyidogan P, Anderson KS
Fission yeast Alp14 is a dose-dependent plus end-tracking microtubule polymerase.
1. Mol Biol Cell - published August 1, 2012
2. Al-Bassam J, Kim H, Flor-Parra I, Lal N, Velji H, Chang F
Structural characterization of a conserved, calcium-dependent periplasmic protease from Legionella pneumophila.
1. J Bacteriol - published August 1, 2012
2. Chatterjee D, Boyd CD, O'Toole GA, Sondermann H
Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.
1. J Biol Chem - published August 1, 2012
2. Hudson RP, Chong PA, Protasevich II, Vernon R, Noy E, Bihler H, An JL, Kalid O, Sela-Culang I, Mense M, Senderowitz H, Brouillette CG, Forman-Kay JD
Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains.
1. EMBO J - published August 1, 2012
2. Bagriantsev SN, Clark KA, Minor DL Jr
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
1. Science - published August 1, 2012
2. Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E
Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts.
1. Methods - published August 1, 2012
2. Marshall CB, Meiri D, Smith MJ, Mazhab-Jafari MT, Gasmi-Seabrook GM, Rottapel R, Stambolic V, Ikura M
Structural insights for engineering binding proteins based on non-antibody scaffolds.
1. Curr Opin Struct Biol - published August 1, 2012
2. Gilbreth RN, Koide S
The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5).
1. J Biol Chem - published August 1, 2012
2. Zhou Y, Zhang H, He B, Du J, Lin H, Cerione RA, Hao Q
Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events.
1. Nat Struct Mol Biol - published August 1, 2012
2. Liokatis S, Stützer A, Elsässer SJ, Theillet FX, Klingberg R, van Rossum B, Schwarzer D, Allis CD, Fischle W, Selenko P
Inhibition of lipopolysaccharide transport to the outer membrane in Pseudomonas aeruginosa by peptidomimetic antibiotics.
1. Chembiochem - published August 1, 2012
2. Werneburg M, Zerbe K, Juhas M, Bigler L, Stalder U, Kaech A, Ziegler U, Obrecht D, Eberl L, Robinson JA
Structural and theoretical basis for ligand exchange on thiolate monolayer protected gold nanoclusters.
1. J Am Chem Soc - published August 1, 2012
2. Heinecke CL, Ni TW, Malola S, Mäkinen V, Wong OA, Häkkinen H, Ackerson CJ
The use of workflows in the design and implementation of complex experiments in macromolecular crystallography.
1. Acta Crystallogr D Biol Crystallogr - published August 1, 2012
2. Brockhauser S, Svensson O, Bowler MW, Nanao M, Gordon E, Leal RM, Popov A, Gerring M, McCarthy AA, Gotz A
RCrane: semi-automated RNA model building.
1. Acta Crystallogr D Biol Crystallogr - published August 1, 2012
2. Keating KS, Pyle AM
Attenuated protein expression vectors for use in siRNA rescue experiments.
1. Biotechniques - published August 1, 2012
2. Morita E, Arii J, Christensen D, Votteler J, Sundquist WI
The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold.
1. Mol Cell - published August 1, 2012
2. Yang Z, Xue B, Umitsu M, Ikura M, Muthuswamy SK, Neel BG
Dissecting neural function using targeted genome engineering technologies.
1. ACS Chem Neurosci - published August 1, 2012
2. Hsu PD, Zhang F
Structural architecture and functional evolution of Wnts.
1. Dev Cell - published August 1, 2012
2. Bazan JF, Janda CY, Garcia KC
Tumor suppression by small molecule inhibitors of translation initiation.
1. Oncotarget - published August 1, 2012
2. Chen L, Aktas BH, Wang Y, He X, Sahoo R, Zhang N, Denoyelle S, Kabha E, Yang H, Freedman RY, Supko JG, Chorev M, Wagner G, Halperin JA
Distribution of Reciprocal of Interatomic Distances: A Fast Structural Metric.
1. J Chem Theory Comput - published August 1, 2012
2. Zhou T, Caflisch A