Member Publications

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75 Member Publications for May 2012

Fabrication of Microgel Particles with Complex Shape via Selective Polymerization of Aqueous Two-Phase Systems.
1. Small - published May 31, 2012
2. WT Huck, C Abell, Y Bai, X Liu, J Thiele, S Ma
Structural Basis of Wnt Recognition by Frizzled.
1. Science - published May 31, 2012
2. KC Garcia, C Thomas, AM Levin, D Waghray, CY Janda
Basic apoptotic and necrotic cell death in human liver carcinoma (HepG(2) ) cells induced by synthetic azamacrocycle.
1. Environ Toxicol - published May 30, 2012
2. MA Saeed, CG Yedjou, PB Tchounwou, H Yu, W Dorsey, M Alamgir Hossain
Structural factors that determine selectivity of a high-fidelity DNA polymerase for deoxy-, dideoxy-, and ribo-nucleotides.
1. J Biol Chem - published May 30, 2012
2. LS Beese, HW Hellinga, EY Wu, W Wang
Replication of n(2) ,3-ethenoguanine by DNA polymerases.
1. Angew Chem Int Ed Engl - published May 29, 2012
2. FP Guengerich, M Egli, CJ Rizzo, PS Pallan, MG Pence, ID Kozekov, PP Christov, L Zhao
A multi-faceted analysis of RutD reveals a novel family of α/β hydrolases.
1. Proteins - published May 29, 2012
2. W Minor, WM Krajewska, M Chruszcz, KA Majorek, DR Cooper, MT Cymborowski, Z Otwinowski, JJ Petkowski, AA Knapik
Structural basis for activation of an integral membrane protease by lipopolysaccharide.
1. J Biol Chem - published May 29, 2012
2. B van den Berg, E Eren
Quantification of the affinities and kinetics of protein interactions using silicon nanowire biosensors.
1. Nat Nanotechnol - published May 27, 2012
2. MA Reed, Y Modis, DA Routenberg, NK Rajan, Y Li, X Duan
Direct and selective small-molecule activation of proapoptotic BAX.
1. Nat Chem Biol - published May 27, 2012
2. LD Walensky, ES Leshchiner, JA Bellairs, DE Reyna, E Gavathiotis
Correction to "fick diffusion coefficients of liquid mixtures directly obtained from equilibrium molecular dynamics".
1. J Phys Chem B - published May 24, 2012
2. TJ Vlugt, A Bardow, S Kjelstrup, D Bedeaux, JM Simon, SK Schnell, X Liu
Plasticity of the β-trefoil protein fold in the recognition and control of invertebrate predators and parasites by a fungal defence system.
1. PLoS Pathog - published May 23, 2012
2. Schubert M, Bleuler-Martinez S, Butschi A, Wälti MA, Egloff P, Stutz K, Yan S, Collot M, Mallet JM, Wilson IB, Hengartner MO, Aebi M, Allain FH, Künzler M
Yohimbine Depresses Excitatory Transmission in BNST and Impairs Extinction of Cocaine Place Preference Through Orexin-Dependent, Norepinephrine-Independent Processes.
1. Neuropsychopharmacology - published May 23, 2012
2. DG Winder, CW Lindsley, JA Javitch, HJ Matthies, N Sen, SA Saleh, AD Shields, DJ Sheffler, Y Silberman, AR Davis, KL Conrad
A Short Segment of the HIV-1 gp120 V1/V2 Region Is a Major Determinant of Resistance to V1/V2 Neutralizing Antibodies.
1. J Virol - published May 23, 2012
2. NA Doria-Rose, JR Mascola, PD Kwong, WC Koff, DR Burton, BF Haynes, M Bonsignori, M Pancera, J Gorman, JS McLellan, RP Staupe, GY Chuang, S O'Dell, I Georgiev
Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs.
1. Chem Commun (Camb) - published May 22, 2012
2. M Egli, TP Prakash, EE Swayze, PP Seth, A Berdeja, CR Allerson, PS Pallan
A General, Enantioselective Synthesis of Protected Morpholines and Piperazines.
1. Org Lett - published May 22, 2012
2. CW Lindsley, MC O'Reilly
(1)H, (13)C and (15)N resonance assignments of the pyrin domain from human PYNOD.
1. Biomol NMR Assign - published May 22, 2012
2. CI Chang, CI Chang, MY Su
Exocyclic Carbons Adjacent to the N(6) of Adenine are Targets for Oxidation by the Escherichia coli Adaptive Response Protein AlkB.
1. J Am Chem Soc - published May 21, 2012
2. JM Essigmann, CL Drennan, C Wong, AS Chen, X Yang, CM Page, JC Delaney, D Li
Wall teichoic acid protects Staphylococcus aureus from inhibition by Congo red and other dyes.
1. J Antimicrob Chemother - published May 21, 2012
2. MS Gilmore, S Walker, E Mylonakis, JG Swoboda, Y Kim, J Campbell, T Suzuki
Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain.
1. PLoS One - published May 19, 2012
2. Cao H, Dai P, Wang W, Li H, Yuan J, Wang F, Fang CM, Pitha PM, Liu J, Condit RC, McFadden G, Merghoub T, Houghton AN, Young JW, Shuman S, Deng L
Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes.
1. PLoS One - published May 17, 2012
2. Briney BS, Willis JR, Crowe JE Jr
Iterative experimental and virtual high-throughput screening identifies metabotropic glutamate receptor subtype 4 positive allosteric modulators.
1. J Mol Model - published May 17, 2012
2. J Meiler, PJ Conn, CW Lindsley, CD Weaver, CR Hopkins, M Butkiewicz, CM Niswender, ES Dawson, R Mueller
Association of Adiposity Trajectories With Insulin Sensitivity and Glycemic Deterioration: A longitudinal study of rural Chinese twin adults.
1. Diabetes Care - published May 17, 2012
2. X Wang, H Xing, Z Li, X Xu, B Wang, D Zimmerman, S Zhang, L Arguelles, G Wang, X Liu, KK Christoffel, WJ Brickman, R Liu
The RGD finger of Del-1 is a unique structural feature critical for integrin binding.
1. FASEB J - published May 17, 2012
2. JH Wang, TA Springer, R Wang, JH Liu, Q Chen, T Schürpf
SMARCE1 Promotes chicken embryonic gonad development by regulating ER α and AR expression.
1. Sex Dev - published May 16, 2012
2. Gong P, Yang Y, Lei W, Feng Y, Li S, Peng X, Gong Y
miR-143 regulates cancer glycolysis via targeting hexokinase 2.
1. J Biol Chem - published May 16, 2012
2. H Ji, X Liu, H Chen, X Liu, Y Wang, L Li, Y Feng, Y Gao, F Li, Y Sun, Z Fang, T Xiao, R Fang
Continued optimization of the MLPCN probe ML071 into highly potent agonists of the hM(1) muscarinic acetylcholine receptor.
1. Bioorg Med Chem Lett - published May 15, 2012
2. MR Wood, CW Lindsley, PJ Conn, CM Niswender, JS Daniels, RD Morrison, TM Bridges, DJ Sheffler, TJ Utley, HP Cho, EP Lebois, BA Chauder, SA Saleh, JC Tarr, RD Gogliotti, BJ Melancon
Structure revision of hupehensis saponin F and G and characterization of new trace triterpenoid saponins from Anemone hupehensis by tandem electrospray ionization mass spectrometry.
1. Carbohydr Res - published May 15, 2012
2. M Wang, L Chen, L Ding, B Chen, M Tang, X Liu, F Li
Radical use of Rossmann and TIM barrel architectures for controlling coenzyme B12 chemistry.
1. Annu Rev Biophys - published May 15, 2012
2. Dowling DP, Croft AK, Drennan CL
FES Kinase Promotes Mast Cell Recruitment to Mammary Tumors Via the Stem Cell Factor/KIT Receptor Signaling Axis.
1. Mol Cancer Res - published May 15, 2012
2. AW Craig, JS Allingham, PA Greer, S Zhang, S Everingham, E Kwok
Real-time correction by optical tracking with integrated geometric distortion correction for reducing motion artifacts in functional MRI.
1. Magn Reson Med - published May 14, 2012
2. SJ Graham, R Chopra, F Tam, S Ranieri, M Chiew, D Rotenberg
Genome sequence of foxtail millet (Setaria italica) provides insights into grass evolution and biofuel potential.
1. Nat Biotechnol - published May 13, 2012
2. Z Zhao, J Wang, Y Li, Q Chen, P Huang, Q Shi, H Xiang, C Liu, Y Cai, T Guo, R Wang, C Wang, J Wang, N Li, H Li, H Li, Y Zhang, J Hu, D Zhan, X Yang, R Cao, X Peng, Q Xia, C Han, C Bian, Y Tao, W Wang, Z Yue, P Zeng, M Xie, S Pan, X Xu, S Cheng, Z Quan, X Liu, G Zhang, J Wang
Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis.
1. PLoS Comput Biol - published May 10, 2012
2. Gaudet S, Spencer SL, Chen WW, Sorger PK
Structural basis for the small G-protein-effector interaction of Ras-related protein 1 (Rap1) and the adaptor protein Krev interaction trapped 1 (KRIT1).
1. J Biol Chem - published May 10, 2012
2. TJ Boggon, DA Calderwood, W Liu, KM Draheim, R Zhang, X Li
Site-specific mapping and time-resolved monitoring of lysine methylation by high-resolution NMR spectroscopy.
1. J Am Chem Soc - published May 9, 2012
2. P Selenko, D Schwarzer, A Binolfi, HM Rose, B Bekei, JO Jost, S Liokatis, FX Theillet
A conserved hydrophobic patch on Vβ domains revealed by TCRβ chain crystal structures: Implications for pre-TCR dimerization.
1. Front Immunol - published May 9, 2012
2. Zhou B, Chen Q, Mallis RJ, Zhang H, Liu JH, Reinherz EL, Wang JH
Conformational change in rhomboid protease GlpG induced by inhibitor binding to its S' subsites.
1. Biochemistry - published May 8, 2012
2. Xue Y, Chowdhury S, Liu X, Akiyama Y, Ellman J, Ha Y
An Asymmetric Dimer as the Basic Subunit in Alzheimer's Disease Amyloid β Fibrils.
1. Angew Chem Int Ed Engl - published May 8, 2012
2. B Reif, M Fändrich, M Dasari, U Fink, M Schmidt, JM Lopez Del Amo
Ultrametricity in Protein Folding Dynamics.
1. J Chem Theory Comput - published May 8, 2012
2. Scalco R, Caflisch A
How Does Darunavir Prevent HIV-1 Protease Dimerization?
1. J Chem Theory Comput - published May 8, 2012
2. Huang D, Caflisch A
A versatile enantioselective synthesis of azabicyclic ring systems: a concise total synthesis of (+)-grandisine d and unnatural analogues.
1. Chemistry - published May 7, 2012
2. CW Lindsley, KN Hahn, TJ Senter, OO Fadeyi
A glutamate switch controls voltage-sensitive phosphatase function.
1. Nat Struct Mol Biol - published May 6, 2012
2. Liu L, Kohout SC, Xu Q, Müller S, Kimberlin CR, Isacoff EY, Minor DL Jr
Cryo-EM Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 and Implications for Ribosome Evolution.
1. J Mol Biol - published May 4, 2012
2. N Ban, I Weygand-Durasevic, M Ibba, A Crnkovic, V Godinic-Mikulcic, D Boehringer, BJ Greber
The amino-terminal helix modulates light-activated conformational changes in AsLOV2.
1. J Mol Biol - published May 2, 2012
2. Zayner JP, Antoniou C, Sosnick TR
Design of Bcl-2 and Bcl-xL inhibitors with subnanomolar binding affinities based upon a new scaffold.
1. J Med Chem - published May 2, 2012
2. Zhou H, Chen J, Meagher JL, Yang CY, Aguilar A, Liu L, Bai L, Cong X, Cai Q, Fang X, Stuckey JA, Wang S
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.
1. J Am Chem Soc - published May 2, 2012
2. Chemler JA, Buchholz TJ, Geders TW, Akey DL, Rath CM, Chlipala GE, Smith JL, Sherman DH
(IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer.
1. Angew Chem Int Ed Engl - published May 2, 2012
2. Marinoni EN, de Oliveira JS, Nicolet Y, Raulfs EC, Amara P, Dean DR, Fontecilla-Camps JC
Structural basis for sigma factor mimicry in the general stress response of Alphaproteobacteria.
1. Proc Natl Acad Sci U S A - published May 2, 2012
2. Campagne S, Damberger FF, Kaczmarczyk A, Francez-Charlot A, Allain FH, Vorholt JA
Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability.
1. Proc Natl Acad Sci U S A - published May 2, 2012
2. Querol-Audí J, Yan C, Xu X, Tsutakawa SE, Tsai MS, Tainer JA, Cooper PK, Nogales E, Ivanov I
LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.
1. Cell - published May 2, 2012
2. Sosa BA, Rothballer A, Kutay U, Schwartz TU
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states.
1. Nature - published May 2, 2012
2. Payandeh J, Gamal El-Din TM, Scheuer T, Zheng N, Catterall WA
Self-association of the histidine kinase CheA as studied by pulsed dipolar ESR spectroscopy.
1. Biophys J - published May 2, 2012
2. Bhatnagar J, Sircar R, Borbat PP, Freed JH, Crane BR
Impact of collagen crosslinking on the second harmonic generation signal and the fluorescence lifetime of collagen autofluorescence.
1. Skin Res Technol - published May 1, 2012
2. Lutz V, Sattler M, Gallinat S, Wenck H, Poertner R, Fischer F
Impact of human adenovirus type 3 dodecahedron on host cells and its potential role in viral infection.
1. J Virol - published May 1, 2012
2. Fender P, Hall K, Schoehn G, Blair GE
Nucleocytoplasmic transport: a role for nonspecific competition in karyopherin-nucleoporin interactions.
1. Mol Cell Proteomics - published May 1, 2012
2. Tetenbaum-Novatt J, Hough LE, Mironska R, McKenney AS, Rout MP
Limited transferrin receptor clustering allows rapid diffusion of canine parvovirus into clathrin endocytic structures.
1. J Virol - published May 1, 2012
2. Cureton DK, Harbison CE, Cocucci E, Parrish CR, Kirchhausen T
Human CD4+ T cell response to human herpesvirus 6.
1. J Virol - published May 1, 2012
2. Nastke MD, Becerra A, Yin L, Dominguez-Amorocho O, Gibson L, Stern LJ, Calvo-Calle JM
Complex physiology and compound stress responses during fermentation of alkali-pretreated corn stover hydrolysate by an Escherichia coli ethanologen.
1. Appl Environ Microbiol - published May 1, 2012
2. Schwalbach MS, Keating DH, Tremaine M, Marner WD, Zhang Y, Bothfeld W, Higbee A, Grass JA, Cotten C, Reed JL, da Costa Sousa L, Jin M, Balan V, Ellinger J, Dale B, Kiley PJ, Landick R
Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection.
1. FEMS Microbiol Rev - published May 1, 2012
2. Hannan TJ, Totsika M, Mansfield KJ, Moore KH, Schembri MA, Hultgren SJ
Fold of the conserved DTC domain in Deltex proteins.
1. Proteins - published May 1, 2012
2. Obiero J, Walker JR, Dhe-Paganon S
Bayesian approach to the analysis of fluorescence correlation spectroscopy data I: theory.
1. Anal Chem - published May 1, 2012
2. He J, Guo SM, Bathe M
Atomic structures of the eukaryotic ribosome.
1. Trends Biochem Sci - published May 1, 2012
2. Klinge S, Voigts-Hoffmann F, Leibundgut M, Ban N
Bayesian approach to the analysis of fluorescence correlation spectroscopy data II: application to simulated and in vitro data.
1. Anal Chem - published May 1, 2012
2. Guo SM, He J, Monnier N, Sun G, Wohland T, Bathe M
Post-translational modifications regulate assembly of early spindle orientation complex in yeast.
1. J Biol Chem - published May 1, 2012
2. Hüls D, Storchova Z, Niessing D
Calcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating.
1. J Biol Chem - published May 1, 2012
2. Ćelić AS, Petri ET, Benbow J, Hodsdon ME, Ehrlich BE, Boggon TJ
Structural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs.
1. Bioorg Med Chem - published May 1, 2012
2. Nandurdikar RS, Maciag AE, Holland RJ, Cao Z, Shami PJ, Anderson LM, Keefer LK, Saavedra JE
ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome.
1. Nat Genet - published May 1, 2012
2. Willer T, Lee H, Lommel M, Yoshida-Moriguchi T, de Bernabe DB, Venzke D, Cirak S, Schachter H, Vajsar J, Voit T, Muntoni F, Loder AS, Dobyns WB, Winder TL, Strahl S, Mathews KD, Nelson SF, Moore SA, Campbell KP
What does it take to stick around? Molecular insights into biofilm formation by uropathogenic Escherichia coli.
1. Virulence - published May 1, 2012
2. Hadjifrangiskou M, Hultgren SJ
Inhibition of bacterial superoxide defense: A new front in the struggle between host and pathogen.
1. Virulence - published May 1, 2012
2. TE Kehl-Fie, EP Skaar, WJ Chazin, S Damo
EGFR in limbo.
1. Cell - published May 1, 2012
2. Eck MJ, Hahn WC
RNase P branches out from RNP to protein: organelle-triggered diversification?
1. Genes Dev - published May 1, 2012
2. Goldfarb KC, Borah S, Cech TR
Structure of the δ-opioid receptor bound to naltrindole.
1. Nature - published May 1, 2012
2. Granier S, Manglik A, Kruse AC, Kobilka TS, Thian FS, Weis WI, Kobilka BK
Drosophila Pur-α binds to trinucleotide-repeat containing cellular RNAs and translocates to the early oocyte.
1. RNA Biol - published May 1, 2012
2. Aumiller V, Graebsch A, Kremmer E, Niessing D, Förstemann K
Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold.
1. Biophys J - published May 1, 2012
2. Wan W, Wille H, Stöhr J, Baxa U, Prusiner SB, Stubbs G
Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
1. Nature - published May 1, 2012
2. Ren A, Rajashankar KR, Patel DJ
Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa AlgL.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published May 1, 2012
2. Wolfram F, Arora K, Robinson H, Neculai AM, Yip P, Howell PL