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87 Member Publications for February 2012

Hydrophobic Core Flexibility Modulates Enzyme Activity in HIV-1 Protease.
1. J Am Chem Soc - published February 28, 2012
2. CA Schiffer, DN Bolon, MN Nalam, Y Cai, S Mittal
Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery.
1. J Med Chem - published February 23, 2012
2. CM Niswender, KA Emmitte, MR Wood, CR Hopkins, BJ Melancon, CW Lindsley, PJ Conn, A Christopoulos
Comparative genomics of enterococci: variation in Enterococcus faecalis, clade structure in E. faecium, and defining characteristics of E. gallinarum and E. casseliflavus.
1. mBio - published February 23, 2012
2. Palmer KL, Godfrey P, Griggs A, Kos VN, Zucker J, Desjardins C, Cerqueira G, Gevers D, Walker S, Wortman J, Feldgarden M, Haas B, Birren B, Gilmore MS
Calcium stabilizes the von Willebrand factor A2 domain by promoting refolding.
1. Proc Natl Acad Sci U S A - published February 22, 2012
2. TA Springer, AJ Xu
Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity.
1. Virol J - published February 22, 2012
2. RS Sitrin, MW Washabaugh, M Kosinski, D Wohlpart, D Abraham, CS Potter, B Carragher, M Brown, J Alexandroff, Y Wang, Y Meng, V Towne, K High, Y Modis, Q Zhao
Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis.
1. Proc Natl Acad Sci U S A - published February 21, 2012
2. S Corvera, KE Fogarty, D Leonard, D Lambright, J Cardia, LM Lifshitz, C Standley, KD Bellvé, DM Navaroli
Inherent structural disorder and dimerisation of murine norovirus NS1-2 protein.
1. PLoS One - published February 21, 2012
2. Baker ES, Luckner SR, Krause KL, Lambden PR, Clarke IN, Ward VK
Aptamers in virology: recent advances and challenges.
1. Front Microbiol - published February 21, 2012
2. Binning JM, Leung DW, Amarasinghe GK
Determinants for Activation of the Atypical AGC Kinase Greatwall During M Phase Entry.
1. Mol Cell Biol - published February 21, 2012
2. ML Goldberg, TM Yamamoto, Y Mao, W Chen, PV Castilho, Y Zhao, BC Williams, KA Blake-Hodek
A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A.
1. Anal Biochem - published February 15, 2012
2. SW Fesik, ET Olejniczak, OW Rossanese, WJ Chazin, DC Dorset, MD Feldkamp, AO Frank, EM Souza-Fagundes
The role of Ile87 of CYP158A2 in oxidative coupling reaction.
1. Arch Biochem Biophys - published February 15, 2012
2. MR Waterman, L Lei, A Bellamine, B Zhao
Binding to retinoblastoma pocket domain does not alter the inter-domain flexibility of the J domain of SV40 large T antigen.
1. Arch Biochem Biophys - published February 15, 2012
2. WJ Chazin, J Pipas, M Hammel, S Vaithiyalingam, CK Williams
A rapid and quantitative coat protein complex II vesicle formation assay using luciferase reporters.
1. Anal Biochem - published February 15, 2012
2. J Kim, JC Fromme
RNA-guided genetic silencing systems in bacteria and archaea.
1. Nature - published February 15, 2012
2. JA Doudna, SH Sternberg, B Wiedenheft
Cyclooxygenase-1-Selective Inhibitors Based on the (E)-2'-Des-methyl-sulindac Sulfide Scaffold.
1. J Med Chem - published February 14, 2012
2. LJ Marnett, K Ghebreselasie, PJ Kingsley, AL Blobaum, CM Daniel, BC Crews, AJ Liedtke
Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling.
1. J Biomol NMR - published February 14, 2012
2. G Wagner, H Arthanari, AB Wagner, AG Milbradt, SG Hyberts
Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism.
1. Biochemistry - published February 13, 2012
2. CH Johnson, X Qin, Y Xu, R Pattanayek, T Mori, M Egli
Engineering antibody fitness and function using membrane-anchored display of correctly folded proteins.
1. J Mol Biol - published February 10, 2012
2. MP DeLisa, A Ke, MA Bratkowski, MA Rocco, H Xu, HK Lim, AJ Karlsson
Host cell nucleolin is required to maintain the architecture of human cytomegalovirus replication compartments.
1. mBio - published February 10, 2012
2. Strang BL, Boulant S, Kirchhausen T, Coen DM
A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles.
1. mBio - published February 10, 2012
2. Shaikh FY, Cox RG, Lifland AW, Hotard AL, Williams JV, Moore ML, Santangelo PJ, Crowe JE Jr
Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation.
1. Science - published February 10, 2012
2. DJ Patel, S Ishibe-Murakami, M Teplova, J Song
RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure.
1. EMBO Rep - published February 10, 2012
2. SC Harrison, F Schmitzberger
Prediction of HIV-1 Protease/Inhibitor Affinity using RosettaLigand.
1. Chem Biol Drug Des - published February 9, 2012
2. J Meiler, K Kaufmann, G Lemmon
Overexpressing human membrane proteins in stably transfected and clonal human embryonic kidney 293S cells.
1. Nat Protoc - published February 9, 2012
2. Chaudhary S, Pak JE, Gruswitz F, Sharma V, Stroud RM
Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.
1. J Am Chem Soc - published February 8, 2012
2. Mortenson DE, Satyshur KA, Guzei IA, Forest KT, Gellman SH
Subunit architecture of general transcription factor TFIIH.
1. Proc Natl Acad Sci U S A - published February 7, 2012
2. Gibbons BJ, Brignole EJ, Azubel M, Murakami K, Voss NR, Bushnell DA, Asturias FJ, Kornberg RD
Replication Bypass of the trans-4-Hydroxynonenal-Derived (6S,8R,11S)-1,N(2)-Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IV.
1. Chem Res Toxicol - published February 7, 2012
2. A Kozekova, PP Christov, S Banerjee, MP Stone, M Egli, CJ Rizzo
MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA.
1. EMBO J - published February 7, 2012
2. Y Modis, IC Berke
Structures of (5'S)-8,5'-Cyclo-2'-deoxyguanosine Mismatched with dA or dT.
1. Chem Res Toxicol - published February 6, 2012
2. MP Stone, AK Basu, RS Das, H Huang
Self-reactive human CD4 T cell clones form unusual immunological synapses.
1. J Exp Med - published February 6, 2012
2. KW Wucherpfennig, ML Dustin, BD Evavold, GT Nepom, H Reijonen, K Choudhuri, NP Seth, DK Sethi, E Gagnon, S Vardhana, Jr Sabatino JJ, S Gordo, DA Schubert
Structure and mechanism of the UvrA-UvrB DNA damage sensor.
1. Nat Struct Mol Biol - published February 5, 2012
2. D Jeruzalmi, JH Hu, K Shen, M Samuels, D Pakotiprapha
Nucleocapsid Protein Annealing of a Primer-Template Enhances (+)-Strand DNA Synthesis and Fidelity by HIV-1 Reverse Transcriptase.
1. J Mol Biol - published February 3, 2012
2. KS Anderson, Y Xiong, H Yuan, A Roberts, J Kim
Bunyavirus: structure and replication.
1. Adv Exp Med Biol - published February 3, 2012
2. Guu TS, Zheng W, Tao YJ
Ab initio protein modeling into cryoEM density maps using EM-Fold.
1. Biopolymers - published February 3, 2012
2. J Meiler, PL Stewart, M Karakaş, N Wötzel, T Hofmann, S Lindert
Efficacy and Safety of Low-Dose Cyclosporine with Everolimus and Steroids in de novo Heart Transplant Patients: A Multicentre, Randomized Trial.
1. J Transplant - published February 2, 2012
2. Zuckermann A, Wang SS, Ross H, Frigerio M, Eisen HJ, Bara C, Hoefer D, Cotrufo M, Dong G, Junge G, Keogh AM
Should a sentinel node biopsy be performed in patients with high-risk breast cancer?
1. Int J Breast Cancer - published February 2, 2012
2. Westover KD, Westover MB, Winer EP, Richardson AL, Iglehart JD, Punglia RS
Structure of saposin A lipoprotein discs.
1. Proc Natl Acad Sci U S A - published February 2, 2012
2. Popovic K, Holyoake J, Pomès R, Privé GG
Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan.
1. Proc Natl Acad Sci U S A - published February 2, 2012
2. Floor SN, Borja MS, Gross JD
Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.
1. Proc Natl Acad Sci U S A - published February 2, 2012
2. Tang X, Orlicky S, Mittag T, Csizmok V, Pawson T, Forman-Kay JD, Sicheri F, Tyers M
Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface.
1. Proc Natl Acad Sci U S A - published February 2, 2012
2. Deaconescu AM, Sevostyanova A, Artsimovitch I, Grigorieff N
Transcriptional pausing coordinates folding of the aptamer domain and the expression platform of a riboswitch.
1. Proc Natl Acad Sci U S A - published February 2, 2012
2. Perdrizet GA 2nd, Artsimovitch I, Furman R, Sosnick TR, Pan T
Structure-function mapping of a heptameric module in the nuclear pore complex.
1. J Cell Biol - published February 2, 2012
2. Fernandez-Martinez J, Phillips J, Sekedat MD, Diaz-Avalos R, Velazquez-Muriel J, Franke JD, Williams R, Stokes DL, Chait BT, Sali A, Rout MP
Structure and dynamics of the M3 muscarinic acetylcholine receptor.
1. Nature - published February 2, 2012
2. Kruse AC, Hu J, Pan AC, Arlow DH, Rosenbaum DM, Rosemond E, Green HF, Liu T, Chae PS, Dror RO, Shaw DE, Weis WI, Wess J, Kobilka BK
The mechanism of OTUB1-mediated inhibition of ubiquitination.
1. Nature - published February 2, 2012
2. Wiener R, Zhang X, Wang T, Wolberger C
Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
1. Nature - published February 2, 2012
2. Armstrong AA, Mohideen F, Lima CD
Pseudomonas aeruginosa Cif defines a distinct class of α/β epoxide hydrolases utilizing a His/Tyr ring-opening pair.
1. Protein Pept Lett - published February 1, 2012
2. Bahl CD, Madden DR
Structural characterization of human Uch37.
1. Proteins - published February 1, 2012
2. Burgie SE, Bingman CA, Soni AB, Phillips GN Jr
Structural basis for specificity of TGFβ family receptor small molecule inhibitors.
1. Cell Signal - published February 1, 2012
2. Ogunjimi AA, Zeqiraj E, Ceccarelli DF, Sicheri F, Wrana JL, David L
Electron tomography of cells.
1. Q Rev Biophys - published February 1, 2012
2. Gan L, Jensen GJ
Ensemble modeling of protein disordered states: experimental restraint contributions and validation.
1. Proteins - published February 1, 2012
2. Marsh JA, Forman-Kay JD
Replication-competent influenza A virus that encodes a split-green fluorescent protein-tagged PB2 polymerase subunit allows live-cell imaging of the virus life cycle.
1. J Virol - published February 1, 2012
2. Avilov SV, Moisy D, Munier S, Schraidt O, Naffakh N, Cusack S
Structure and activity of DmmA, a marine haloalkane dehalogenase.
1. Protein Sci - published February 1, 2012
2. Gehret JJ, Gu L, Geders TW, Brown WC, Gerwick L, Gerwick WH, Sherman DH, Smith JL
Integrin inside-out signaling and the immunological synapse.
1. Curr Opin Cell Biol - published February 1, 2012
2. Springer TA, Dustin ML
Three-dimensional structure of basal body triplet revealed by electron cryo-tomography.
1. EMBO J - published February 1, 2012
2. Li S, Fernandez JJ, Marshall WF, Agard DA
Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae.
1. Mol Biol Cell - published February 1, 2012
2. Bertin A, McMurray MA, Pierson J, Thai L, McDonald KL, Zehr EA, García G 3rd, Peters P, Thorner J, Nogales E
Nucleic acid recognition by tandem helical repeats.
1. Curr Opin Struct Biol - published February 1, 2012
2. Rubinson EH, Eichman BF
Crystal structure of the Japanese encephalitis virus envelope protein.
1. J Virol - published February 1, 2012
2. Luca VC, AbiMansour J, Nelson CA, Fremont DH
Human cytomegalovirus UL44 concentrates at the periphery of replication compartments, the site of viral DNA synthesis.
1. J Virol - published February 1, 2012
2. Strang BL, Boulant S, Chang L, Knipe DM, Kirchhausen T, Coen DM
Facile double-functionalization of designed ankyrin repeat proteins using click and thiol chemistries.
1. Bioconjug Chem - published February 1, 2012
2. Simon M, Zangemeister-Wittke U, Plückthun A
Interaction surface and topology of Get3-Get4-Get5 protein complex, involved in targeting tail-anchored proteins to endoplasmic reticulum.
1. J Biol Chem - published February 1, 2012
2. Chang YW, Lin TW, Li YC, Huang YS, Sun YJ, Hsiao CD
Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2.
1. J Biol Chem - published February 1, 2012
2. Gareau JR, Reverter D, Lima CD
γδ T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion.
1. J Biol Chem - published February 1, 2012
2. Sandstrom A, Scharf L, McRae G, Hawk AJ, Meredith SC, Adams EJ
C-terminal di-arginine motif of Cdc42 protein is essential for binding to phosphatidylinositol 4,5-bisphosphate-containing membranes and inducing cellular transformation.
1. J Biol Chem - published February 1, 2012
2. Johnson JL, Erickson JW, Cerione RA
3D ultrastructure of the nuclear pore complex.
1. Curr Opin Cell Biol - published February 1, 2012
2. Bilokapic S, Schwartz TU
A procedure to validate and correct the 13C chemical shift calibration of RNA datasets.
1. J Biomol NMR - published February 1, 2012
2. Aeschbacher T, Schubert M, Allain FH
Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases.
1. Cell Cycle - published February 1, 2012
2. U Rodeck, R Armen, JM Pascal, TO Chan
Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase.
1. Biochemistry - published February 1, 2012
2. Bailey LJ, Acheson JF, McCoy JG, Elsen NL, Phillips GN Jr, Fox BG
Thiosuccinyl peptides as Sirt5-specific inhibitors.
1. J Am Chem Soc - published February 1, 2012
2. He B, Du J, Lin H
Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase.
1. Bioorg Med Chem Lett - published February 1, 2012
2. Ekkati AR, Bollini M, Domaoal RA, Spasov KA, Anderson KS, Jorgensen WL
Structural studies of the spinosyn rhamnosyltransferase, SpnG.
1. Biochemistry - published February 1, 2012
2. Isiorho EA, Liu HW, Keatinge-Clay AT
Two ZnF-UBP domains in isopeptidase T (USP5).
1. Biochemistry - published February 1, 2012
2. Avvakumov GV, Walker JR, Xue S, Allali-Hassani A, Asinas A, Nair UB, Fang X, Zuo X, Wang YX, Wilkinson KD, Dhe-Paganon S
Using large-scale neural models to interpret connectivity measures of cortico-cortical dynamics at millisecond temporal resolution.
1. Front Syst Neurosci - published February 1, 2012
2. Banerjee A, Pillai AS, Horwitz B
Live-cell imaging of clathrin coats.
1. Methods Enzymol - published February 1, 2012
2. Kural C, Kirchhausen T
Lysozyme contamination facilitates crystallization of a heterotrimeric cortactin-Arg-lysozyme complex.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published February 1, 2012
2. TJ Boggon, AJ Koleske, SM Macgrath, W Liu
Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published February 1, 2012
2. Joseph RE, Ginder ND, Hoy JA, Nix JC, Fulton DB, Honzatko RB, Andreotti AH
Crystallization and preliminary X-ray diffraction analysis of human dipeptidyl peptidase 10 (DPPY), a component of voltage-gated potassium channels.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published February 1, 2012
2. Bezerra GA, Dobrovetsky E, Seitova A, Dhe-Paganon S, Gruber K
Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa PelD.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published February 1, 2012
2. Marmont LS, Whitney JC, Robinson H, Colvin KM, Parsek MR, Howell PL
Two-step demodulation based on the Gram-Schmidt orthonormalization method.
1. Opt Lett - published February 1, 2012
2. Vargas J, Quiroga JA, Sorzano CO, Estrada JC, Carazo JM
The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.
1. Genes Dev - published February 1, 2012
2. Lavy T, Kumar PR, He H, Joshua-Tor L
Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger.
1. Science - published February 1, 2012
2. Liao J, Li H, Zeng W, Sauer DB, Belmares R, Jiang Y
A jumbo problem: mapping the structure and functions of the nuclear pore complex.
1. Curr Opin Cell Biol - published February 1, 2012
2. Fernandez-Martinez J, Rout MP
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.
1. Mol Cell - published February 1, 2012
2. Juang YC, Landry MC, Sanches M, Vittal V, Leung CC, Ceccarelli DF, Mateo AR, Pruneda JN, Mao DY, Szilard RK, Orlicky S, Munro M, Brzovic PS, Klevit RE, Sicheri F, Durocher D
Unravelling the lamina network.
1. Nat Rev Mol Cell Biol - published February 1, 2012
2. Zwerger M, Medalia O
The structural basis of transferrin sequestration by transferrin-binding protein B.
1. Nat Struct Mol Biol - published February 1, 2012
2. Calmettes C, Alcantara J, Yu RH, Schryvers AB, Moraes TF
CoSMoS unravels mysteries of transcription initiation.
1. Cell - published February 1, 2012
2. Gourse RL, Landick R
Structure based antibody-like peptidomimetics.
1. Pharmaceuticals (Basel) - published February 1, 2012
2. Murali R, Greene MI
HIV-1 Protease and Substrate Coevolution Validates the Substrate Envelope As the Substrate Recognition Pattern.
1. J Chem Theory Comput - published February 1, 2012
2. Ozen A, Haliloğlu T, Schiffer CA