Member Publications

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58 Member Publications for January 2012

The structural basis for substrate versatility of chloramphenicol acetyltransferase CAT(I).
1. Protein Sci - published January 31, 2012
2. OV Tsodikov, S Garneau-Tsodikova, JL Houghton, T Biswas
Millisecond Time-Scale Folding and Unfolding of DNA Hairpins Using Rapid-Mixing Stopped-Flow Kinetics.
1. J Am Chem Soc - published January 30, 2012
2. A Van Orden, KB Hall, OB Peersen, RK Nayak
An antibiotic that inhibits a late step in wall teichoic acid biosynthesis induces the cell wall stress stimulon in Staphylococcus aureus.
1. Antimicrob Agents Chemother - published January 30, 2012
2. S Walker, BJ Wilkinson, MS Gilmore, JG Swoboda, AK Singh, J Campbell
Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel.
1. Science - published January 27, 2012
2. R Mackinnon, J del Mármol, SG Brohawn
GARP regulates the bioavailability and activation of TGFβ
1. Mol Biol Cell - published January 25, 2012
2. TA Springer, C Lu, M Shi, X Dong, J Zhu, R Wang
Selection of Monoclonal Antibodies Against 6-oxo-M(1)dG and Their Use in an LC-MS/MS Assay for the Presence of 6-oxo-M(1)dG in Vivo.
1. Chem Res Toxicol - published January 24, 2012
2. LJ Marnett, J Szekely, R Carnahan, T Cooper, SC Shuck, PJ Kingsley, D Akingbade
Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition.
1. J Exp Med - published January 23, 2012
2. R Tiedt, M Murakami, V Romanet, E Vangrevelinghe, C Gaul, A Yoda, JE Bradner, RM Paranal, M McKeown, AL Christie, S Marubayashi, AV Toms, D van Bodegom, B Chapuy, N Kopp, L Bird, AA Lane, O Weigert, DM Weinstock, T Radimerski, F Baffert, AL Kung, RL Levine, SE Sallan, MJ Eck, F Hofmann, D Erdmann, CH Régnier, A De Pover, E Evrot, N Ebel
A Three-dimensional Structure of Steroid 21-Hydroxylase (Cytochrome P450 21A2) with Two Substrates Reveals Locations of Disease-associated Variants.
1. J Biol Chem - published January 18, 2012
2. MR Waterman, FP Guengerich, LD Nagy, S Banerjee, M Sundaramoorthy, N Kagawa, L Lei, B Zhao
Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012.
1. Bioorg Med Chem Lett - published January 15, 2012
2. MR Wood, CW Lindsley, P Jeffrey Conn, CK Jones, CM Niswender, J Scott Daniels, RD Morrison, MJ Noetzel, DJ Sheffler, TJ Utley, GA Sulikowski, TM Bridges, AP Lamers, BJ Melancon
Designed ankyrin repeat proteins (DARPins) from research to therapy.
1. Methods Enzymol - published January 11, 2012
2. Tamaskovic R, Simon M, Stefan N, Schwill M, Plückthun A
Domain architecture of a calcium-permeable AMPA receptor in a ligand-free conformation.
1. Front Mol Neurosci - published January 11, 2012
2. Midgett CR, Gill A, Madden DR
Prokaryotic diacylglycerol kinase and undecaprenol kinase.
1. Annu Rev Biophys - published January 10, 2012
2. Van Horn WD, Sanders CR
Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
1. Annu Rev Biophys - published January 10, 2012
2. Park E, Rapoport TA
Insights from crystal structures into the opposite effects on RNA affinity caused by the s- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic Acid.
1. Biochemistry - published January 10, 2012
2. M Egli, P Seth, EE Swayze, CR Allerson, J Yu, PS Pallan
Structural specializations of α4β7, an integrin that mediates rolling adhesion.
1. J Cell Biol - published January 9, 2012
2. TA Springer, J Chen, H Sun, T Walz, LZ Mi, J Zhu, Y Yu
Chromodomains read the arginine code of post-translational targeting.
1. Nat Struct Mol Biol - published January 8, 2012
2. Holdermann I, Meyer NH, Round A, Wild K, Sattler M, Sinning I
Tissue transglutaminase and its role in human cancer progression.
1. Adv Enzymol Relat Areas Mol Biol - published January 7, 2012
2. Li B, Cerione RA, Antonyak M
Cross-monomer substrate contacts reposition the Hsp90 N-terminal domain and prime the chaperone activity.
1. J Mol Biol - published January 6, 2012
2. Street TO, Lavery LA, Verba KA, Lee CT, Mayer MP, Agard DA
Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.
1. J Biol Chem - published January 6, 2012
2. Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnölzer M, Verdin E, Zhou MM, Ott M
Dystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGE.
1. Science - published January 6, 2012
2. Inamori K, Yoshida-Moriguchi T, Hara Y, Anderson ME, Yu L, Campbell KP
A transcription activator-like effector toolbox for genome engineering.
1. Nat Protoc - published January 5, 2012
2. Sanjana NE, Cong L, Zhou Y, Cunniff MM, Feng G, Zhang F
A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
1. EMBO J - published January 4, 2012
2. Daubner GM, Cléry A, Jayne S, Stevenin J, Allain FH
Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.
1. Proc Natl Acad Sci U S A - published January 3, 2012
2. Ren Z, Srajer V, Knapp JE, Royer WE Jr
Metal ion-mediated DNA-protein interactions.
1. Met Ions Life Sci - published January 3, 2012
2. Zambelli B, Musiani F, Ciurli S
Wilms tumor gene on the X chromosome (WTX) inhibits the degradation of NRF2 through competitive binding to KEAP1.
1. J Biol Chem - published January 3, 2012
2. RT Moon, MB Major, N Zheng, X Tang, SA Houck, JM Davison, F Yan, DW Dawson, RG James, ND Camp
Structural studies of AntD: an N-Acyltransferase involved in the biosynthesis of D-Anthrose.
1. Biochemistry - published January 3, 2012
2. Kubiak RL, Holden HM
Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue.
1. Biochemistry - published January 3, 2012
2. Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB
Conserved structural mechanisms for autoinhibition in IpaH ubiquitin ligases.
1. J Biol Chem - published January 2, 2012
2. Chou YC, Keszei AFA, Rohde JR, Tyers M, Sicheri F
Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini.
1. J Biol Chem - published January 2, 2012
2. Ouyang H, Ali YO, Ravichandran M, Dong A, Qiu W, MacKenzie F, Dhe-Paganon S, Arrowsmith CH, Zhai RG
Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature.
1. Virology - published January 2, 2012
2. Sabo MC, Luca VC, Ray SC, Bukh J, Fremont DH, Diamond MS
Emerging role of lipid droplets in host/pathogen interactions.
1. J Biol Chem - published January 2, 2012
2. Herker E, Ott M
Electron microscopy visualization of DNA-protein complexes formed by Ku and DNA ligase IV.
1. DNA Repair (Amst) - published January 2, 2012
2. Grob P, Zhang TT, Hannah R, Yang H, Hefferin ML, Tomkinson AE, Nogales E
Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate.
1. J Biol Chem - published January 2, 2012
2. Xue Y, Ha Y
A reverse binding motif that contributes to specific protease inhibition by antibodies.
1. J Mol Biol - published January 2, 2012
2. Schneider EL, Lee MS, Baharuddin A, Goetz DH, Farady CJ, Ward M, Wang CI, Craik CS
Crystal structure of the human two-pore domain potassium channel K2P1.
1. Science - published January 2, 2012
2. Miller AN, Long SB
Structural and functional conservation of key domains in InsP3 and ryanodine receptors.
1. Nature - published January 2, 2012
2. Seo MD, Velamakanni S, Ishiyama N, Stathopulos PB, Rossi AM, Khan SA, Dale P, Li C, Ames JB, Ikura M, Taylor CW
Discovery of potent and selective covalent inhibitors of JNK.
1. Chem Biol - published January 2, 2012
2. Zhang T, Inesta-Vaquera F, Niepel M, Zhang J, Ficarro SB, Machleidt T, Xie T, Marto JA, Kim N, Sim T, Laughlin JD, Park H, LoGrasso PV, Patricelli M, Nomanbhoy TK, Sorger PK, Alessi DR, Gray NS
Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation.
1. Nucleic Acids Res - published January 1, 2012
2. Wei SY, Lou YC, Tsai JY, Ho MR, Chou CC, Rajasekaran M, Hsu HM, Tai JH, Hsiao CD, Chen C
DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe.
1. Nucleic Acids Res - published January 1, 2012
2. Nandakumar J, Cech TR
Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme.
1. Mol Biosyst - published January 1, 2012
2. Zambelli B, Cremades N, Neyroz P, Turano P, Uversky VN, Ciurli S
The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis.
1. Gynecol Oncol - published January 1, 2012
2. Romero IL, Lee W, Mitra AK, Gordon IO, Zhao Y, Leonhardt P, Penicka CV, Mui KL, Krausz TN, Greene GL, Lengyel E
Single-chain Fv-based anti-HIV proteins: potential and limitations.
1. J Virol - published January 1, 2012
2. West AP Jr, Galimidi RP, Gnanapragasam PN, Bjorkman PJ
Modeling large regions in proteins: applications to loops, termini, and folding.
1. Protein Sci - published January 1, 2012
2. Adhikari AN, Peng J, Wilde M, Xu J, Freed KF, Sosnick TR
A strongly bound high-spin iron(II) coordinates cysteine and homocysteine in cysteine dioxygenase.
1. Biochemistry - published January 1, 2012
2. Tchesnokov EP, Wilbanks SM, Jameson GN
Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin.
1. Proc Natl Acad Sci U S A - published January 1, 2012
2. Liu J, Xu Y, Stoleru D, Salic A
Endpoint measures in the mdx mouse relevant for muscular dystrophy pre-clinical studies.
1. Neuromuscul Disord - published January 1, 2012
2. Kobayashi YM, Rader EP, Crawford RW, Campbell KP
Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca²+-free interdomain linkers.
1. Proc Natl Acad Sci U S A - published January 1, 2012
2. Jin X, Walker MA, Felsövályi K, Vendome J, Bahna F, Mannepalli S, Cosmanescu F, Ahlsen G, Honig B, Shapiro L
YBR246W is required for the third step of diphthamide biosynthesis.
1. J Am Chem Soc - published January 1, 2012
2. Su X, Chen W, Lee W, Jiang H, Zhang S, Lin H
Structural features and kinetic characterization of alanine racemase from Staphylococcus aureus (Mu50).
1. Acta Crystallogr D Biol Crystallogr - published January 1, 2012
2. Scaletti ER, Luckner SR, Krause KL
Cleavage furrow organization requires PIP(2)-mediated recruitment of anillin.
1. Curr Biol - published January 1, 2012
2. Liu J, Fairn GD, Ceccarelli DF, Sicheri F, Wilde A
Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published January 1, 2012
2. Lay FT, Mills GD, Hulett MD, Kvansakul M
Complete subunit architecture of the proteasome regulatory particle.
1. Nature - published January 1, 2012
2. Lander GC, Estrin E, Matyskiela ME, Bashore C, Nogales E, Martin A
Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors.
1. PLoS Pathog - published January 1, 2012
2. Buschiazzo A, Muiá R, Larrieux N, Pitcovsky T, Mucci J, Campetella O
Structural basis for recognition of H3T3ph and Smac/DIABLO N-terminal peptides by human Survivin.
1. Structure - published January 1, 2012
2. Du J, Kelly AE, Funabiki H, Patel DJ
Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.
1. Nature - published January 1, 2012
2. Zhang DS, Piazza V, Perrin BJ, Rzadzinska AK, Poczatek JC, Wang M, Prosser HM, Ervasti JM, Corey DP, Lechene CP
Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis.
1. J Neurosci - published January 1, 2012
2. Badea TC, Williams J, Smallwood P, Shi M, Motajo O, Nathans J
SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication.
1. Genes Dev - published January 1, 2012
2. Bétous R, Mason AC, Rambo RP, Bansbach CE, Badu-Nkansah A, Sirbu BM, Eichman BF, Cortez D
50 Years of Lifson-Roig Models: Application to Molecular Simulation Data.
1. J Chem Theory Comput - published January 1, 2012
2. Vitalis A, Caflisch A