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67 Member Publications for December 2011

Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression.
1. PLoS One - published December 24, 2011
2. Bian S, Bai JP, Chapin H, Le Moellic C, Dong H, Caplan M, Sigworth FJ, Navaratnam DS
Mechanism of nucleotide sensing in group II chaperonins.
1. EMBO J - published December 23, 2011
2. PD Adams, J Frydman, JA King, KM Knee, RP McAndrew, T Lopez, R Kumar, NR Douglas, CY Ralston, JH Pereira
Editorial management of the Journal of Biomolecular NMR.
1. J Biomol NMR - published December 23, 2011
2. G Wagner
Explicit treatment of water molecules in data-driven protein-protein docking: the solvated HADDOCKing approach.
1. Methods Mol Biol - published December 21, 2011
2. Kastritis PL, van Dijk AD, Bonvin AM
Human DNA Helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress.
1. J Biol Chem - published December 21, 2011
2. E Fanning, WJ Chazin, E Kremmer, DR Arnett, S Vaithiyalingam, H Liu, GD Guler
Searching for DNA Lesions: Structural Evidence for Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine DNA Glycosylase.
1. Biochemistry - published December 20, 2011
2. CL Drennan, LD Samson, CA Davis, GM Lingaraju, JW Setser
NMEGylation: a novel modification to enhance the bioavailability of therapeutic peptides.
1. Biopolymers - published December 20, 2011
2. Park M, Jardetzky TS, Barron AE
The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix.
1. Environ Microbiol - published December 19, 2011
2. MR Parsek, DJ Wozniak, PL Howell, C Ryder, JC Whitney, R Urbano, CS Tart, Y Irie, KM Colvin
Adaptation to tRNA acceptor stem structure by flexible adjustment in the catalytic domain of class I tRNA synthetases.
1. RNA - published December 19, 2011
2. YM Hou, JM Pascal, JM Sanders, C Liu
From Mitochondrial Biology to Magic Bullet: Navitoclax Disarms BCL-2 in Chronic Lymphocytic Leukemia.
1. J Clin Oncol - published December 19, 2011
2. LD Walensky
Mutations altering the interplay between GkDnaC helicase and DNA reveal an insight into helicase unwinding.
1. PLoS One - published December 17, 2011
2. Lo YH, Liu SW, Sun YJ, Li HW, Hsiao CD
Structural insights into charge pair interactions in triple helical collagen-like proteins.
1. J Biol Chem - published December 17, 2011
2. JD Hartgerink, YJ Tao, J Dong, JA Fallas
Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition.
1. Proc Natl Acad Sci U S A - published December 12, 2011
2. S Hur, T Walz, M Liu, M Orme-Johnson, B Wu, C Lin, A Peisley
The Mechanism of Interaction of Human Mitochondrial DNA Polymerase γ with the Novel Nucleoside Reverse Transcriptase Inhibitor 4' -Ethynyl-2-Fluoro-2' -Deoxyadenosine Indicates a Low Potential for Host Toxicity.
1. Antimicrob Agents Chemother - published December 12, 2011
2. KS Anderson, SG Sarafianos, H Mitsuya, WC Copeland, R Kasiviswanathan, K Singh, CD Sohl
Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase.
1. Proc Natl Acad Sci U S A - published December 12, 2011
2. CL Drennan, J Stubbe, FJ Asturias, K Yokoyama, MA Funk, CM Zimanyi, EJ Brignole, N Ando
Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes.
1. FEBS J - published December 12, 2011
2. DC Lamb, SL Kelly, MR Waterman, JG Mullins, DR Nelson, L Lei, B Zhao, SC Moody
Intrinsic tethering activity of endosomal Rab proteins.
1. Nat Struct Mol Biol - published December 11, 2011
2. AJ Merz, T Gonen, S Fields, M Vignali, RL Plemel, CL Brett, SY Lo
The C-Terminal αI Domain Linker as a Critical Structural Element in the Conformational Activation of αI Integrins.
1. J Biol Chem - published December 9, 2011
2. TA Springer, T Schürpf, G Weitz-Schmidt
Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis.
1. J Biol Chem - published December 9, 2011
2. Harris C, Herker E, Farese RV Jr, Ott M
Structural basis for promoter-10 element recognition by the bacterial RNA polymerase σ subunit.
1. Cell - published December 9, 2011
2. Feklistov A, Darst SA
Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins.
1. Cell - published December 9, 2011
2. Slattery M, Riley T, Liu P, Abe N, Gomez-Alcala P, Dror I, Zhou T, Rohs R, Honig B, Bussemaker HJ, Mann RS
Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.
1. Cell - published December 9, 2011
2. Guettler S, LaRose J, Petsalaki E, Gish G, Scotter A, Pawson T, Rottapel R, Sicheri F
Lock and key to transcription: σ-DNA interaction.
1. Cell - published December 9, 2011
2. Liu X, Bushnell DA, Kornberg RD
Secreted semaphorins from degenerating larval ORN axons direct adult projection neuron dendrite targeting.
1. Neuron - published December 8, 2011
2. Sweeney LB, Chou YH, Wu Z, Joo W, Komiyama T, Potter CJ, Kolodkin AL, Garcia KC, Luo L
A quantitative fluorometric approach for measuring the interaction of RhoGDI with membranes and Rho GTPases.
1. Methods Mol Biol - published December 7, 2011
2. Johnson J, Cerione RA, Erickson JW
Ndc10 is a platform for inner kinetochore assembly in budding yeast.
1. Nat Struct Mol Biol - published December 4, 2011
2. SC Harrison, US Cho
Open structure of the Ca(2+) gating ring in the high-conductance Ca(2+)-activated K(+) channel.
1. Nature - published December 4, 2011
2. R Mackinnon, Y Hsiung, MD Leonetti, P Yuan
Assignment strategies for aliphatic protons in the solid-state in randomly protonated proteins.
1. J Biomol NMR - published December 4, 2011
2. B Reif, S Asami
Synthesis, properties, and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage.
1. Acc Chem Res - published December 2, 2011
2. Li NS, Frederiksen JK, Piccirilli JA
The molecular interactions that stabilize RNA tertiary structure: RNA motifs, patterns, and networks.
1. Acc Chem Res - published December 2, 2011
2. Butcher SE, Pyle AM
Disordered binding of small molecules to Aβ(12-28).
1. J Biol Chem - published December 2, 2011
2. Convertino M, Vitalis A, Caflisch A
Bispecific designed ankyrin repeat proteins (DARPins) targeting epidermal growth factor receptor inhibit A431 cell proliferation and receptor recycling.
1. J Biol Chem - published December 2, 2011
2. Boersma YL, Chao G, Steiner D, Wittrup KD, Plückthun A
Skeletal fusion of small heterocycles with amphoteric molecules.
1. Angew Chem Int Ed Engl - published December 2, 2011
2. Cheung LL, He Z, Decker SM, Yudin AK
Computationally-guided optimization of a docking hit to yield catechol diethers as potent anti-HIV agents.
1. J Med Chem - published December 2, 2011
2. Bollini M, Domaoal RA, Thakur VV, Gallardo-Macias R, Spasov KA, Anderson KS, Jorgensen WL
Solution NMR approaches for establishing specificity of weak heterodimerization of membrane proteins.
1. J Am Chem Soc - published December 2, 2011
2. Zhuang T, Jap BK, Sanders CR
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3).
1. Proc Natl Acad Sci U S A - published December 2, 2011
2. Sun C, Todorovic A, Querol-Audí J, Bai Y, Villa N, Snyder M, Ashchyan J, Lewis CS, Hartland A, Gradia S, Fraser CS, Doudna JA, Nogales E, Cate JH
Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
1. Proc Natl Acad Sci U S A - published December 2, 2011
2. Torbeev VY, Raghuraman H, Hamelberg D, Tonelli M, Westler WM, Perozo E, Kent SB
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.
1. Nature - published December 2, 2011
2. Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, Sali A, Craik CS, Harris RS, Gross JD, Krogan NJ
Global landscape of HIV-human protein complexes.
1. Nature - published December 2, 2011
2. Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD, Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS, Burlingame A, Sali A, Frankel AD, Krogan NJ
How a DNA polymerase clamp loader opens a sliding clamp.
1. Science - published December 2, 2011
2. Kelch BA, Makino DL, O'Donnell M, Kuriyan J
The microbial opsin family of optogenetic tools.
1. Cell - published December 2, 2011
2. Zhang F, Vierock J, Yizhar O, Fenno LE, Tsunoda S, Kianianmomeni A, Prigge M, Berndt A, Cushman J, Polle J, Magnuson J, Hegemann P, Deisseroth K
A poised chromatin platform for TGF-β access to master regulators.
1. Cell - published December 2, 2011
2. Xi Q, Wang Z, Zaromytidou AI, Zhang XH, Chow-Tsang LF, Liu JX, Kim H, Barlas A, Manova-Todorova K, Kaartinen V, Studer L, Mark W, Patel DJ, Massagué J
Visualizing proteins and macromolecular complexes by negative stain EM: from grid preparation to image acquisition.
1. J Vis Exp - published December 2, 2011
2. Booth DS, Avila-Sakar A, Cheng Y
Modular synthesis of diphospholipid oligosaccharide fragments of the bacterial cell wall and their use to study the mechanism of moenomycin and other antibiotics.
1. Tetrahedron - published December 2, 2011
2. Gampe CM, Tsukamoto H, Wang TS, Walker S, Kahne D
Dynamic MRI Analysis of Tumor and Organ Motion During Rest and Deglutition and Margin Assessment for Radiotherapy of Head-and-Neck Cancer.
1. Int J Radiat Oncol Biol Phys - published December 1, 2011
2. D Wang, XA Li, C Schultz, E Ahunbay, ES Paulson, JA Bradley
DARPins and other repeat protein scaffolds: advances in engineering and applications.
1. Curr Opin Biotechnol - published December 1, 2011
2. Boersma YL, Plückthun A
S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used?
1. Bioorg Chem - published December 1, 2011
2. Lin H
Correlating crosslink formation with enzymatic activity in cysteine dioxygenase.
1. Biochim Biophys Acta - published December 1, 2011
2. Siakkou E, Rutledge MT, Wilbanks SM, Jameson GN
CNS live imaging reveals a new mechanism of myelination: the liquid croissant model.
1. Glia - published December 1, 2011
2. Sobottka B, Ziegler U, Kaech A, Becher B, Goebels N
Efficient expression screening of human membrane proteins in transiently transfected Human Embryonic Kidney 293S cells.
1. Methods - published December 1, 2011
2. Chaudhary S, Pak JE, Pedersen BP, Bang LJ, Zhang LB, Ngaw SM, Green RG, Sharma V, Stroud RM
Rapid identification of recombinant Fabs that bind to membrane proteins.
1. Methods - published December 1, 2011
2. Kim J, Stroud RM, Craik CS
Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.
1. Mol Biol Cell - published December 1, 2011
2. Zhang ZC, Satterly N, Fontoura BM, Chook YM
Understanding histone acetyltransferase Rtt109 structure and function: how many chaperones does it take?
1. Curr Opin Struct Biol - published December 1, 2011
2. D'Arcy S, Luger K
Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu(4)) antagonist: Unexpected 'molecular switch' from a closely related mGlu(4) positive allosteric modulator.
1. Bioorg Med Chem Lett - published December 1, 2011
2. CM Niswender, CR Hopkins, CW Lindsley, PN Vinson, R Zamorano, JM Salovich, D Haddenham, T Utley
Measurement of aptamer-protein interactions with back-scattering interferometry.
1. Anal Chem - published December 1, 2011
2. DJ Bornhop, HT Soh, J Meiler, JH Sheehan, AT Csordas, M Cho, Y Xiao, IR Olmsted
Characterization of the PilN, PilO and PilP type IVa pilus subcomplex.
1. Mol Microbiol - published December 1, 2011
2. Tammam S, Sampaleanu LM, Koo J, Sundaram P, Ayers M, Chong PA, Forman-Kay JD, Burrows LL, Howell PL
Altering the Electrostatic Potential in the Major Groove: Thermodynamic and Structural Characterization of 7-Deaza-2'-deoxyadenosine:dT Base Pairing in DNA.
1. J Phys Chem B - published December 1, 2011
2. MP Stone, M Egli, B Gold, LA Marky, PS Pallan, M Ganguly, EA Kowal
Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.
1. J Gen Physiol - published December 1, 2011
2. Pan AC, Cuello LG, Perozo E, Roux B
Dystrophin deficiency exacerbates skeletal muscle pathology in dysferlin-null mice.
1. Skelet Muscle - published December 1, 2011
2. Han R, Rader EP, Levy JR, Bansal D, Campbell KP
Crystal structure of the bacteriophage T4 late-transcription coactivator gp33 with the β-subunit flap domain of Escherichia coli RNA polymerase.
1. Proc Natl Acad Sci U S A - published December 1, 2011
2. SA Darst, A Hochschild, EP Geiduschek, V Jain, S Nechaev, P Deighan, EA Campbell, KA Twist
Roles of M1 muscarinic acetylcholine receptor subtype in regulation of basal ganglia function and implications for treatment of Parkinson's disease.
1. J Pharmacol Exp Ther - published December 1, 2011
2. PJ Conn, CW Lindsley, CK Jones, AD Thompson, Z Xiang
Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation.
1. J Cell Biol - published December 1, 2011
2. Garcia G 3rd, Bertin A, Li Z, Song Y, McMurray MA, Thorner J, Nogales E
Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28.
1. Nat Struct Mol Biol - published December 1, 2011
2. Loughlin FE, Gebert LF, Towbin H, Brunschweiger A, Hall J, Allain FH
Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal.
1. J Cell Biol - published December 1, 2011
2. Hori K, Sen A, Kirchhausen T, Artavanis-Tsakonas S
Microtubules in bacteria: Ancient tubulins build a five-protofilament homolog of the eukaryotic cytoskeleton.
1. PLoS Biol - published December 1, 2011
2. Pilhofer M, Ladinsky MS, McDowall AW, Petroni G, Jensen GJ
Chemical informatics and target identification in a zebrafish phenotypic screen.
1. Nat Chem Biol - published December 1, 2011
2. Laggner C, Kokel D, Setola V, Tolia A, Lin H, Irwin JJ, Keiser MJ, Cheung CY, Minor DL Jr, Roth BL, Peterson RT, Shoichet BK
Self-assembly of amelogenin proteins at the water-oil interface.
1. Eur J Oral Sci - published December 1, 2011
2. Martinez-Avila OM, Wu S, Cheng Y, Lee R, Khan F, Habelitz S