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60 Member Publications for October 2011

Speeding up direct (15)N detection: hCaN 2D NMR experiment.
1. J Biomol NMR - published October 30, 2011
2. G Wagner, K Takeuchi, AG Milbradt, KA Edmonds, M Gal
Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design.
1. Science - published October 27, 2011
2. PJ Bjorkman, MC Nussenzweig, MS Seaman, A Abadir, PN Gnanapragasam, H Gao, F Klein, Jr West AP, PM Marcovecchio, JF Scheid, R Diskin
Post-Translational Modifications and Lipid Binding Profile of Insect Cell-Expressed Full-Length Mammalian Synaptotagmin 1.
1. Biochemistry - published October 26, 2011
2. AT Brunger, S Chu, KC Hansen, RC Hill, P Strop, M Vrljic
Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.
1. Nature - published October 26, 2011
2. TP Begley, SE Ealick, DH Russell, PC Dorrestein, PJ Pai, S Bale, ND Abeydeera, A Chatterjee
Structural basis for norovirus inhibition and fucose mimicry by citrate.
1. J Virol - published October 26, 2011
2. PD Kwong, CA Bewley, K Katayama, T Shimoike, I Georgiev, GY Chuang, JS McLellan, S Shahzad-Ul-Hussan, GS Hansman
Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation.
1. PLoS One - published October 25, 2011
2. Aster JC, Bodnar N, Xu L, Karnell F, Milholland JM, Maillard I, Histen G, Nam Y, Blacklow SC, Pear WS
Phylogeny of Oedogoniales, Chaetophorales and Chaetopeltidales (Chlorophyceae): inferences from sequence-structure analysis of ITS2.
1. Ann Bot - published October 25, 2011
2. M Wolf, F Förster, T Schleicher, DM Sutherland, MA Buchheim
The spliceosome and its metal ions.
1. Met Ions Life Sci - published October 20, 2011
2. Butcher SE
Discovery, Synthesis, and Structure-Activity Relationship Development of a Series of N-4-(2,5-Dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu(4)) with Oral Efficacy in an Antiparkinsonian Animal Model.
1. J Med Chem - published October 19, 2011
2. Y Zhou, SR Lindsley, AL Blobaum, JR Field, AD Thompson, DW Engers, CK Jones, CR Hopkins, CM Niswender, CW Lindsley, PJ Conn, CD Weaver, JS Daniels, R Morrison, Y Smith, J Bogenpohl, R Zamorano, S Jadhav, RD Gogliotti
Paramagnetic relaxation enhancement to improve sensitivity of fast NMR methods: application to intrinsically disordered proteins.
1. J Biomol NMR - published October 19, 2011
2. P Selenko, S Verzini, S Liokatis, A Binolfi, FX Theillet
Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
1. Proc Natl Acad Sci U S A - published October 17, 2011
2. LS Beese, HW Hellinga, W Wang
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization.
1. Nat Struct Mol Biol - published October 16, 2011
2. EL Reinherz, G Wagner, JR Engen, JH Wang, PD Kwong, Y Yang, G Ofek, S Majumdar, AF Fahmy, Y Cheng, L Song, X Shi, KD Rand, ZY Sun, M Kim
3D Mapping of the SPRY2 domain of ryanodine receptor 1 by single-particle cryo-EM.
1. PLoS One - published October 15, 2011
2. Perálvarez-Marín A, Tae H, Board PG, Casarotto MG, Dulhunty AF, Samsó M
Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly.
1. J Biol Chem - published October 13, 2011
2. G Wagner, MS Wolfe, H Arthanari, S Narayanan
Progress in the rational design of an AIDS vaccine.
1. Philos Trans R Soc Lond B Biol Sci - published October 12, 2011
2. JR Mascola, PD Kwong, GJ Nabel
Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
1. Proc Natl Acad Sci U S A - published October 12, 2011
2. MA Marletta, J Kuriyan, Jr Herzik MA, MB Winter
Bacterial transcription terminators: the RNA 3'-end chronicles.
1. J Mol Biol - published October 7, 2011
2. Peters JM, Vangeloff AD, Landick R
Efficient discovery of potent anti-HIV agents targeting the Tyr181Cys variant of HIV reverse transcriptase.
1. J Am Chem Soc - published October 5, 2011
2. Jorgensen WL, Bollini M, Thakur VV, Domaoal RA, Spasov KA, Anderson KS
Optimization of van der waals energy for protein side-chain placement and design.
1. Biophys J - published October 5, 2011
2. G Wagner, A Fahmy
DNA methyl transferase 1: regulatory mechanisms and implications in health and disease.
1. Int J Biochem Mol Biol - published October 5, 2011
2. Dhe-Paganon S, Syeda F, Park L
Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
1. Proc Natl Acad Sci U S A - published October 4, 2011
2. Sauer DB, Zeng W, Raghunathan S, Jiang Y
Oligomeric structure of the MALT1 tandem Ig-like domains.
1. PLoS One - published October 4, 2011
2. Qiu L, Dhe-Paganon S
The histone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events.
1. J Biol Chem - published October 3, 2011
2. K Luger, AR Hieb, UM Muthurajan, DD Winkler
A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
1. J Mol Biol - published October 2, 2011
2. Akey DL, Li S, Konwerski JR, Confer LA, Bernard SM, Anzai Y, Kato F, Sherman DH, Smith JL
A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration.
1. J Biol Chem - published October 2, 2011
2. Boroughs LK, Antonyak MA, Johnson JL, Cerione RA
Crystal structure of cardiac troponin C regulatory domain in complex with cadmium and deoxycholic acid reveals novel conformation.
1. J Mol Biol - published October 2, 2011
2. Li AY, Lee J, Borek D, Otwinowski Z, Tibbits GF, Paetzel M
Crystal structure of an RNA polymerase ribozyme in complex with an antibody fragment.
1. Philos Trans R Soc Lond B Biol Sci - published October 2, 2011
2. Piccirilli JA, Koldobskaya Y
Use of a coenzyme by the glmS ribozyme-riboswitch suggests primordial expansion of RNA chemistry by small molecules.
1. Philos Trans R Soc Lond B Biol Sci - published October 2, 2011
2. Ferré-D'Amaré AR
Solvatochromic reagents for multicomponent reactions and their utility in the development of cell-permeable macrocyclic peptide vectors.
1. Chemistry - published October 2, 2011
2. Rotstein BH, Mourtada R, Kelley SO, Yudin AK
Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity.
1. Proc Natl Acad Sci U S A - published October 2, 2011
2. Chang A, Singh S, Helmich KE, Goff RD, Bingman CA, Thorson JS, Phillips GN Jr
Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
1. Nat Struct Mol Biol - published October 2, 2011
2. Szyk A, Deaconescu AM, Piszczek G, Roll-Mecak A
Biochemistry. How proteins fold.
1. Science - published October 2, 2011
2. Sosnick TR, Hinshaw JR
Employing modular polyketide synthase ketoreductases as biocatalysts in the preparative chemoenzymatic syntheses of diketide chiral building blocks.
1. Chem Biol - published October 2, 2011
2. Piasecki SK, Taylor CA, Detelich JF, Liu J, Zheng J, Komsoukaniants A, Siegel DR, Keatinge-Clay AT
Ancestral roles of small RNAs: an Ago-centric perspective.
1. Cold Spring Harb Perspect Biol - published October 1, 2011
2. Joshua-Tor L, Hannon GJ
1H, 13C and 15N assignment of the GNA1946 outer membrane lipoprotein from Neisseria meningitidis.
1. Biomol NMR Assign - published October 1, 2011
2. Neumoin A, Leonchiks A, Petit P, Vuillard L, Pizza M, Soriani M, Boelens R, Bonvin AM
1H, 13C and 15N chemical shift assignments of IPSEΔNLS.
1. Biomol NMR Assign - published October 1, 2011
2. Meyer NH, Schramm G, Sattler M
A centrifugation-free high-throughput protein purification system using in-line microfluidization.
1. Protein Expr Purif - published October 1, 2011
2. Alenkin D, Yermekbayeva L, Mujib S, Vesterberg A, Newman E, Yamazaki K, Cossar D, Dhe-Paganon S
ABCA1 increases extracellular ATP to mediate cholesterol efflux to ApoA-I.
1. Am J Physiol Cell Physiol - published October 1, 2011
2. Lee JY, Karwatsky J, Ma L, Zha X
An adaptation of the Wiener filter suitable for analyzing images of isolated single particles.
1. J Struct Biol - published October 1, 2011
2. Sindelar CV, Grigorieff N
Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP.
1. Trends Cell Biol - published October 1, 2011
2. Al-Bassam J, Chang F
Cryo-electron tomography: gaining insight into cellular processes by structural approaches.
1. Curr Opin Struct Biol - published October 1, 2011
2. Yahav T, Maimon T, Grossman E, Dahan I, Medalia O
Rous sarcoma virus gag has no specific requirement for phosphatidylinositol-(4,5)-bisphosphate for plasma membrane association in vivo or for liposome interaction in vitro.
1. J Virol - published October 1, 2011
2. Chan J, Dick RA, Vogt VM
Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.
1. J Virol - published October 1, 2011
2. Dai P, Cao H, Merghoub T, Avogadri F, Wang W, Parikh T, Fang CM, Pitha PM, Fitzgerald KA, Rahman MM, McFadden G, Hu X, Houghton AN, Shuman S, Deng L
A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin.
1. J Virol - published October 1, 2011
2. Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Basler CF, Crowe JE Jr
Visualizing kinetochore architecture.
1. Curr Opin Struct Biol - published October 1, 2011
2. Alushin G, Nogales E
Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.
1. Mol Endocrinol - published October 1, 2011
2. Coopman K, Wallis R, Robb G, Brown AJ, Wilkinson GF, Timms D, Willars GB
Individual filamentous phage imaged by electron holography.
1. Eur Biophys J - published October 1, 2011
2. Stevens GB, Krüger M, Latychevskaia T, Lindner P, Plückthun A, Fink HW
Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence.
1. J Immunol - published October 1, 2011
2. Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Briney BS, Smith SA, Basler CF, Crowe JE Jr
Human C-type lectin domain family 4, member C (CLEC4C/BDCA-2/CD303) is a receptor for asialo-galactosyl-oligosaccharides.
1. J Biol Chem - published October 1, 2011
2. Riboldi E, Daniele R, Parola C, Inforzato A, Arnold PL, Bosisio D, Fremont DH, Bastone A, Colonna M, Sozzani S
Amino acid determinants of substrate selectivity in the Trypanosoma brucei sphingolipid synthase family.
1. Biochemistry - published October 1, 2011
2. Goren MA, Fox BG, Bangs JD
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides.
1. J Am Chem Soc - published October 1, 2011
2. Egli M, Pallan PS, Allerson CR, Prakash TP, Berdeja A, Yu J, Lee S, Watt A, Gaus H, Bhat B, Swayze EE, Seth PP
Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous system.
1. ACS Chem Neurosci - published October 1, 2011
2. Lebois EP, Bridges TM, Lewis LM, Dawson ES, Kane AS, Xiang Z, Jadhav SB, Yin H, Kennedy JP, Meiler J, Niswender CM, Jones CK, Conn PJ, Weaver CD, Lindsley CW
A tale of two callings.
1. J Clin Invest - published October 1, 2011
2. Lefkowitz RJ
Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection.
1. Proc Natl Acad Sci U S A - published October 1, 2011
2. Hara Y, Kanagawa M, Kunz S, Yoshida-Moriguchi T, Satz JS, Kobayashi YM, Zhu Z, Burden SJ, Oldstone MB, Campbell KP
Microtubule nucleation by γ-tubulin complexes.
1. Nat Rev Mol Cell Biol - published October 1, 2011
2. Kollman JM, Merdes A, Mourey L, Agard DA
Using structure to explore the sequence alignment space of remote homologs.
1. PLoS Comput Biol - published October 1, 2011
2. Kuziemko A, Honig B, Petrey D
Advances in structural and functional analysis of membrane proteins by electron crystallography.
1. Structure - published October 1, 2011
2. Wisedchaisri G, Reichow SL, Gonen T
Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA.
1. Cell - published October 1, 2011
2. Kowalinski E, Lunardi T, McCarthy AA, Louber J, Brunel J, Grigorov B, Gerlier D, Cusack S
Structural insights into RNA recognition by RIG-I.
1. Cell - published October 1, 2011
2. Luo D, Ding SC, Vela A, Kohlway A, Lindenbach BD, Pyle AM
Modeling the hydration layer around proteins: applications to small- and wide-angle x-ray scattering.
1. Biophys J - published October 1, 2011
2. Virtanen JJ, Makowski L, Sosnick TR, Freed KF