Member Publications

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63 Member Publications for September 2011

Enzymology of RNA cap synthesis.
1. Wiley Interdiscip Rev RNA - published September 30, 2011
2. Ghosh A, Lima CD
Analysis of substrate specificity of Schizosaccharomyces pombe Mag1 alkylpurine DNA glycosylase.
1. EMBO Rep - published September 30, 2011
2. BF Eichman, S Adhikary
Introduction to Lipid Biochemistry, Metabolism, and Signaling.
1. Chem Rev - published September 27, 2011
2. LJ Marnett, HA Brown
Highly Diastereoselective and General Synthesis of Primary β-Fluoroamines.
1. Org Lett - published September 26, 2011
2. CW Lindsley, ML Schulte
Phospholipase D: Enzymology, Functionality, and Chemical Modulation.
1. Chem Rev - published September 22, 2011
2. HA Brown, CW Lindsley, RR Lavieri, PE Selvy
Structures of the RNA-guided surveillance complex from a bacterial immune system.
1. Nature - published September 21, 2011
2. E Nogales, JA Doudna, J van der Oost, SJ Brouns, MM Jore, K Zhou, GC Lander, B Wiedenheft
Design of Native-like Proteins through an Exposure-Dependent Environment Potential.
1. Biochemistry - published September 19, 2011
2. J Meiler, B Dorr, S Deluca
Endocannabinoid Oxygenation by Cyclooxygenases, Lipoxygenases, and Cytochromes P450: Cross-Talk between the Eicosanoid and Endocannabinoid Signaling Pathways.
1. Chem Rev - published September 19, 2011
2. LJ Marnett, CA Rouzer
Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex.
1. Proc Natl Acad Sci U S A - published September 19, 2011
2. A Hoelz, G Blobel, EW Debler, HS Seo, K Yoshida
Simultaneous use of solution, solid-state NMR and X-ray crystallography to study the conformational landscape of the Crh protein during oligomerization and crystallization.
1. Adv Appl Bioinform Chem - published September 16, 2011
2. Bardiaux B, Favier A, Etzkorn M, Baldus M, Böckmann A, Nilges M, Malliavin TE
Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).
1. Bioorg Med Chem Lett - published September 15, 2011
2. J Chao, AG Taveras, WC Lee, T Li, S Zhao, S Khan, R Morena, Q Wang, N Timple, N Takeda, M Reff, M Teng, L Ling, L Silvian, LS Gan, K Nguyen, K Vu, K Hong, K Lundgren, J Piao, JY Le Brazidec, G Xiao, D Marcotte, D Aivazian, D Wang, C Boykin, C Gilson, BY Tam, A Cesena, JH Chong, J Fan, L Zhang
Structure and Mechanism of PhnP, a Phosphodiesterase of the Carbon-Phosphorus Lyase Pathway.
1. Biochemistry - published September 15, 2011
2. DL Zechel, Z Jia, B Hove-Jensen, A Asfaw, FR McSorley, M Wong, K Podzelinska, M Wathier, SM He
Formation of a N(2)-dG:N(2)-dG Carbinolamine DNA Cross-link by the trans-4-Hydroxynonenal-Derived (6S,8R,11S) 1,N(2)-dG Adduct.
1. J Am Chem Soc - published September 14, 2011
2. MP Stone, CJ Rizzo, A Kozekova, H Wang, H Huang
(1)H, (15)N and (13)C backbone and side-chain resonance assignments of a family 32 carbohydrate-binding module from the Clostridium perfringens NagH.
1. Biomol NMR Assign - published September 13, 2011
2. SP Smith, AB Boraston, E Ficko-Blean, S Chitayat, JM Grondin
Structural flexibility of the G{alpha}s {alpha}-helical domain in the {beta}2-adrenoceptor Gs complex.
1. Proc Natl Acad Sci U S A - published September 13, 2011
2. T Liu, PS Chae, E Pardon, AN Oleskie, G Velez-Ruiz, D Calinski, KY Chung, BT Devree, S Dutta, M Su, SG Rasmussen, GH Westfield, G Skiniotis, RK Sunahara, BK Kobilka, J Steyaert, Jr Woods VL, S Li
Genetic Basis for In Vivo Daptomycin Resistance in Enterococci.
1. N Engl J Med - published September 8, 2011
2. GM Weinstock, BE Murray, Y Shamoo, JP Quinn, W Arap, R Pasqualini, E Sodergren, E Lobos, JH Roh, J Reyes, EM Barbu, S Rincon, TT Tran, L Diaz, C Miller, MF Mojica, X Qin, DM McGrath, D Panesso, CA Arias
Amphoteric α-boryl aldehydes.
1. J Am Chem Soc - published September 7, 2011
2. He Z, Yudin AK
Fluorinated Cyclooxygenase-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer.
1. Cancer Prev Res (Phila) - published September 7, 2011
2. LJ Marnett, JJ Reese, MN Tantawy, MS Ansari, PJ Kingsley, I Huda, K Ghebreselasie, BC Crews, MJ Uddin
Small molecule binding to proteins: affinity and binding/unbinding dynamics from atomistic simulations.
1. ChemMedChem - published September 5, 2011
2. Huang D, Caflisch A
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response.
1. Science - published September 3, 2011
2. Gardner BM, Walter P
Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium.
1. Cell - published September 3, 2011
2. Whorton MR, MacKinnon R
Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
1. J Biol Chem - published September 2, 2011
2. Sawa J, Malet H, Krojer T, Canellas F, Ehrmann M, Clausen T
Crystal Structure of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Csn2 Protein Revealed Ca2+-dependent Double-stranded DNA Binding Activity.
1. J Biol Chem - published September 2, 2011
2. A Ke, I Kurinov, KH Nam
Atomic structure of bacteriophage Sf6 tail needle knob.
1. J Biol Chem - published September 2, 2011
2. Bhardwaj A, Molineux IJ, Casjens SR, Cingolani G
Enzyme inhibition by allosteric capture of an inactive conformation.
1. J Mol Biol - published September 2, 2011
2. Lee GM, Shahian T, Baharuddin A, Gable JE, Craik CS
CSAR benchmark exercise of 2010: selection of the protein-ligand complexes.
1. J Chem Inf Model - published September 2, 2011
2. Dunbar JB Jr, Smith RD, Yang CY, Ung PM, Lexa KW, Khazanov NA, Stuckey JA, Wang S, Carlson HA
A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport.
1. J Biol Chem - published September 2, 2011
2. Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E Jr., Rudnick G, Noskov SY, DeFelice LJ, Meiler J, Blakely RD
Structural complexity of a composite amyloid fibril.
1. J Am Chem Soc - published September 2, 2011
2. Lewandowski JR, van der Wel PC, Rigney M, Grigorieff N, Griffin RG
Solution-based structural analysis of the decaheme cytochrome, MtrA, by small-angle X-ray scattering and analytical ultracentrifugation.
1. J Phys Chem B - published September 2, 2011
2. Firer-Sherwood MA, Ando N, Drennan CL, Elliott SJ
Tolerance to changes in membrane lipid composition as a selected trait of membrane proteins.
1. Biochemistry - published September 2, 2011
2. Sanders CR, Mittendorf KF
Structural Basis of the Substrate Specificity of Bifunctional Isocitrate Dehydrogenase Kinase/Phosphatase.
1. Biochemistry - published September 2, 2011
2. Z Jia, J Zheng, LJ Stewart, PJ Myler, WC Van Voorhis, AJ Stein, CM Bryan, TE Edwards, SP Yates
Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding.
1. Mol Cell - published September 2, 2011
2. Kleiman LB, Maiwald T, Conzelmann H, Lauffenburger DA, Sorger PK
Peptidoglycan remodeling and conversion of an inner membrane into an outer membrane during sporulation.
1. Cell - published September 2, 2011
2. Tocheva EI, Matson EG, Morris DM, Moussavi F, Leadbetter JR, Jensen GJ
A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca(2+)/Calmodulin- Dependent Kinase II Holoenzyme.
1. Cell - published September 2, 2011
2. J Kuriyan, H Schulman, JT Groves, T Kortemme, DJ Mandell, J Levitz, OS Rosenberg, IH Lee, MM Stratton, LH Chao
Organization of the smallest eukaryotic spindle.
1. Curr Biol - published September 2, 2011
2. Gan L, Ladinsky MS, Jensen GJ
Accessing protein conformational ensembles using room-temperature X-ray crystallography.
1. Proc Natl Acad Sci U S A - published September 2, 2011
2. Fraser JS, van den Bedem H, Samelson AJ, Lang PT, Holton JM, Echols N, Alber T
Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization.
1. Proc Natl Acad Sci U S A - published September 2, 2011
2. Xue Y, Lee S, Ha Y
Regulation of integrin affinity on cell surfaces.
1. EMBO J - published September 2, 2011
2. Schürpf T, Springer TA
Nuclear import by karyopherin-βs: recognition and inhibition.
1. Biochim Biophys Acta - published September 1, 2011
2. Chook YM, Süel KE
Crystal structure of an enzymatically inactive trans-sialidase-like lectin from Trypanosoma cruzi: the carbohydrate binding mechanism involves residual sialidase activity.
1. Biochim Biophys Acta - published September 1, 2011
2. Oppezzo P, Obal G, Baraibar MA, Pritsch O, Alzari PM, Buschiazzo A
N-Methylimidazolium chloride-catalyzed pyrophosphate formation: Application to the synthesis of Lipid I and NDP-sugar donors.
1. Bioorg Med Chem Lett - published September 1, 2011
2. D Kahne, H Tsukamoto
Quantifying ligand bias at seven-transmembrane receptors.
1. Mol Pharmacol - published September 1, 2011
2. Rajagopal S, Ahn S, Rominger DH, Gowen-MacDonald W, Lam CM, Dewire SM, Violin JD, Lefkowitz RJ
A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop.
1. Nucleic Acids Res - published September 1, 2011
2. Martin-Tumasz S, Richie AC, Clos LJ 2nd, Brow DA, Butcher SE
A conserved archaeal pathway for tail-anchored membrane protein insertion.
1. Traffic - published September 1, 2011
2. Sherrill J, Mariappan M, Dominik P, Hegde RS, Keenan RJ
β-Arrestin-mediated receptor trafficking and signal transduction.
1. Trends Pharmacol Sci - published September 1, 2011
2. Shenoy SK, Lefkowitz RJ
Immune activation and suppression by group B streptococcus in a murine model of urinary tract infection.
1. Infect Immun - published September 1, 2011
2. Kline KA, Schwartz DJ, Lewis WG, Hultgren SJ, Lewis AL
Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking.
1. Traffic - published September 1, 2011
2. Ivanovic T, Boulant S, Ehrlich M, Demidenko AA, Arnold MM, Kirchhausen T, Nibert ML
Quantitative use of chemical shifts for the modeling of protein complexes.
1. Proteins - published September 1, 2011
2. Stratmann D, Boelens R, Bonvin AM
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling.
1. Trends Biochem Sci - published September 1, 2011
2. Shukla AK, Xiao K, Lefkowitz RJ
A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors.
1. Cancer Res - published September 1, 2011
2. Sasaki T, Koivunen J, Ogino A, Yanagita M, Nikiforow S, Zheng W, Lathan C, Marcoux JP, Du J, Okuda K, Capelletti M, Shimamura T, Ercan D, Stumpfova M, Xiao Y, Weremowicz S, Butaney M, Heon S, Wilner K, Christensen JG, Eck MJ, Wong KK, Lindeman N, Gray NS, Rodig SJ, Jänne PA
Preclinical assessment of CNS drug action using eye movements in mice.
1. J Clin Invest - published September 1, 2011
2. Cahill H, Rattner A, Nathans J
Halogen-substituted (C-β-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase.
1. Bioorg Med Chem - published September 1, 2011
2. Alexacou KM, Zhang YZ, Praly JP, Zographos SE, Chrysina ED, Oikonomakos NG, Leonidas DD
Impact of de novo everolimus-based immunosuppression on incisional complications in heart transplantation.
1. Transplantation - published September 1, 2011
2. Zuckermann A, Arizon JM, Dong G, Eisen HJ, Kobashigawa J, Lehmkuhl H, Ross H, Pelligrini C, Wang SS, Barten MJ
Two-step interferometry by a regularized optical flow algorithm.
1. Opt Lett - published September 1, 2011
2. Vargas J, Quiroga JA, Sorzano CO, Estrada JC, Carazo JM
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc.
1. Cell - published September 1, 2011
2. CS Mitsiades, JE Bradner, AL Kung, KC Anderson, WC Hahn, RA Young, PG Richardson, IM Ghobrial, PL Bergsagel, CR Vakoc, TP Heffernan, MR McKeown, AC Schinzel, M Chesi, J Qi, RM Paranal, T Gilpatrick, E Kastritis, HM Jacobs, J Shi, PB Rahl, ME Lemieux, GC Issa, JE Delmore
Use of chromophoric ligands to visually screen co-crystals of putative protein-nucleic acid complexes.
1. Curr Protoc Nucleic Acid Chem - published September 1, 2011
2. Jiang X, Egli M
Structure of trifunctional THI20 from yeast.
1. Acta Crystallogr D Biol Crystallogr - published September 1, 2011
2. French JB, Begley TP, Ealick SE
Chemistry and structural biology of DNA damage and biological consequences.
1. Chem Biodivers - published September 1, 2011
2. Stone MP, Huang H, Brown KL, Shanmugam G
Maturation-induced cloaking of neutralization epitopes on HIV-1 particles.
1. PLoS Pathog - published September 1, 2011
2. Joyner AS, Willis JR, Crowe JE Jr, Aiken C
The feasibility of parameterizing four-state equilibria using relaxation dispersion measurements.
1. J Biomol NMR - published September 1, 2011
2. Li P, Martins IR, Rosen MK
Zn-binding AZUL domain of human ubiquitin protein ligase Ube3A.
1. J Biomol NMR - published September 1, 2011
2. Lemak A, Yee A, Bezsonova I, Dhe-Paganon S, Arrowsmith CH
Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1.
1. Cold Spring Harb Perspect Med - published September 1, 2011
2. Kwong PD, Mascola JR, Nabel GJ
Chemical synthesis of hydrocarbon-stapled peptides for protein interaction research and therapeutic targeting.
1. Curr Protoc Chem Biol - published September 1, 2011
2. Bird GH, Crannell WC, Walensky LD