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73 Member Publications for August 2011

Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
1. Nature - published August 28, 2011
2. R Mackinnon, X Tao, SB Hansen
Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine.
1. Protein Sci - published August 24, 2011
2. SE Ealick, AE Pegg, 3rd Secrist JA, JH Thomas, DE McCloskey, J Sečkutė, HJ Thomas
Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
1. Proc Natl Acad Sci U S A - published August 23, 2011
2. SL Mayo, PJ Bjorkman, J Yong, SK Gillespie, PN Gnanapragasam, JR Keeffe
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).
1. Proc Natl Acad Sci U S A - published August 23, 2011
2. R Bucala, O Lesur, G Mor, E Lolis, J Bernhagen, F Chagnon, H Xiong, Y Chen, H Lue, J Fan, W Schulte, X Du, R Das, L Leng, S Zierow, M Merk
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin.
1. Proc Natl Acad Sci U S A - published August 23, 2011
2. SC Harrison, HX Liao, TB Kepler, MA Moody, EB Walter, BF Haynes, PR Dormitzer, H Golding, J Manischewitz, LR King, S Khurana, R Zhang, JR Whittle
Regulation of the catalytic activity of the EGF receptor.
1. Curr Opin Struct Biol - published August 23, 2011
2. J Kuriyan, E Kovacs, R Das, K Engel, NF Endres
Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch.
1. Proc Natl Acad Sci U S A - published August 22, 2011
2. A Serganov, DJ Patel, S Ishibe-Murakami, L Huang
Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk.
1. Proc Natl Acad Sci U S A - published August 22, 2011
2. TS Jardetzky, RA Lamb, RG Paterson, GP Leser, KA Swanson, P Yuan
Ganglioside mediate the interaction between Nogo receptor 1 and LINGO-1.
1. Biochem Biophys Res Commun - published August 22, 2011
2. D Nikolov, J Himanen, M Semavina, MV Kolev, N Saha
RNA helicases and remodeling proteins.
1. Curr Opin Chem Biol - published August 20, 2011
2. AM Pyle
Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons.
1. Cell - published August 19, 2011
2. PO Krutzik, D Levin, I Moraga, C Thomas, KC Garcia, G Schreiber, J Piehler, GP Nolan, JS Glenn, SE Vleck, G Yarden, C Lee, A Trejo, Y Podoplelova
A pH-regulated dimeric bouquet in the structure of von Willebrand factor.
1. EMBO J - published August 19, 2011
2. TA Springer, T Walz, C Lu, N Nishida, ET Eng, YF Zhou
Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus.
1. Cell Host Microbe - published August 18, 2011
2. EP Skaar, WJ Chazin, KA Munro, C Garcia, N Restrepo, S Damo, MI Hood, S Chitayat, TE Kehl-Fie
Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV.
1. J Am Chem Soc - published August 17, 2011
2. MP Stone, M Egli, KL Brown, S Banerjee
Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates.
1. Science - published August 17, 2011
2. G Skiniotis, K Karbstein, 3rd Brooks CL, J Schilling, S Cheng, H Vashisth, M Su, CR Loucks, BS Strunk
Protein-selective capture to analyze electrophile adduction of hsp90 by 4-hydroxynonenal.
1. Chem Res Toxicol - published August 15, 2011
2. DC Liebler, LJ Marnett, RE Connor
Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch.
1. Nat Chem Biol - published August 14, 2011
2. A Serganov, DJ Patel, A Polonskaia, O Pikovskaya
The Chlamydia effector, chlamydial outer protein N CopN), sequesters tubulin and prevents microtubule assembly.
1. J Biol Chem - published August 13, 2011
2. BW Spiller, R Ohi, MD Ohi, C Lesser, S Lory, CA English, Y Du, TL Archuleta
Determinants of the Higher Order Association of the Restriction Factor TRIM5{alpha} and Other Tripartite Motif (TRIM) Proteins.
1. J Biol Chem - published August 12, 2011
2. J Sodroski, AM Fiegen, DF Yeung, X Li
The Reconstituted Escherichia coli Bam Complex Catalyzes Multiple Rounds of β-Barrel Assembly.
1. Biochemistry - published August 11, 2011
2. D Kahne, CL Hagan
Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing.
1. Science - published August 11, 2011
2. JR Mascola, PD Kwong, L Shapiro, M Roederer, GJ Nabel, JC Mullikin, Program NISC Comparative Sequencing, M Connors, N Doria-Rose, WC Koff, DR Burton, M Simek, BF Haynes, NE Sam, SH Kapiga, JA Crump, M Bonsignori, Z Zhang, Z Yang, ZY Yang, Y Yang, L Wu, W Shi, SD Schmidt, S Perfetto, S O'Dell, K McKee, M Louder, NS Longo, X Chen, C Wang, I Georgiev, B Zhang, J Zhu, T Zhou, X Wu, NA Doria-Rose
Structural basis for alginate secretion across the bacterial outer membrane.
1. Proc Natl Acad Sci U S A - published August 9, 2011
2. Whitney JC, Hay ID, Li C, Eckford PD, Robinson H, Amaya MF, Wood LF, Ohman DE, Bear CE, Rehm BH, Howell PL
Intact {alpha}IIb{beta}3 extends after activation measured by solution x-ray scattering and electron microscopy.
1. J Biol Chem - published August 9, 2011
2. TA Springer, T Walz, BJ Smagghe, ET Eng
Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.
1. Sci Signal - published August 9, 2011
2. Nobles KN, Xiao K, Ahn S, Shukla AK, Lam CM, Rajagopal S, Strachan RT, Huang TY, Bressler EA, Hara MR, Shenoy SK, Gygi SP, Lefkowitz RJ
Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly.
1. J Cell Biol - published August 8, 2011
2. Lu L, Ladinsky MS, Kirchhausen T
Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.
1. Nat Struct Mol Biol - published August 7, 2011
2. T Walz, N Nishida, Z Li, C Lu, LZ Mi, TA Springer
Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
1. Nat Struct Mol Biol - published August 7, 2011
2. DJ Patel, E Izaurralde, NW Khin, L Wohlbold, M Teplova
Crucial points within the pore as determinants of K⁺ channel conductance and gating.
1. J Mol Biol - published August 5, 2011
2. Shi N, Zeng W, Ye S, Li Y, Jiang Y
Structure-Based Identification and Neutralization Mechanism of Tyrosine Sulfate Mimetics That Inhibit HIV-1 Entry.
1. ACS Chem Biol - published August 5, 2011
2. PD Kwong, CA Bewley, JR Mascola, JA Hoxie, KS Watts, L Martin, TS Luongo, JR Greenwood, AK Debnath, LL Frye, MK Louder, GJ Leslie, SN Lam, JM Lalonde, C Dogo-Isonagie, P Acharya
Isolation and characterization of type I antifreeze proteins from cunner, Tautogolabrus adspersus, Order Perciformes.
1. FEBS J - published August 5, 2011
2. GL Fletcher, PL Davies, LA Graham, MA Shears, RS Hobbs
Structures of Cryptococcus neoformans protein farnesyltransferase reveal strategies for developing inhibitors that target fungal pathogens.
1. J Biol Chem - published August 4, 2011
2. LS Beese, JA Alspaugh, HW Hellinga, SM Kelly, SM Armstrong, CB Nichols, MA Hast
Luminescence of polyethylene glycol coated CdSeTe/ZnS and InP/ZnS nanoparticles in the presence of copper cations.
1. Chemphyschem - published August 2, 2011
2. Beaune G, Tamang S, Bernardin A, Bayle-Guillemaud P, Fenel D, Schoehn G, Vinet F, Reiss P, Texier I
Identification of Calmodulin and MlcC as Light Chains for Dictyostelium Myosin-I Isozymes.
1. Biochemistry - published August 2, 2011
2. GP Côté, SP Smith, Y Jung, K Shaw, J Liburd, SW Crawley
Structural basis of multifunctionality in a vitamin B12-processing enzyme.
1. J Biol Chem - published August 2, 2011
2. Koutmos M, Gherasim C, Smith JL, Banerjee R
The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.
1. Biochemistry - published August 2, 2011
2. SE Ealick, M Terreni, I Serra, J Piškur, WB Parker, PW Allan, S Christoffersen, TH Tran
Crystal structure of the E2 domain of amyloid precursor protein-like protein 1 in complex with sucrose octasulfate.
1. J Biol Chem - published August 2, 2011
2. Xue Y, Lee S, Wang Y, Ha Y
Solution structure of the Mycobacterium tuberculosis EsxG·EsxH complex: functional implications and comparisons with other M. tuberculosis Esx family complexes.
1. J Biol Chem - published August 2, 2011
2. Ilghari D, Lightbody KL, Veverka V, Waters LC, Muskett FW, Renshaw PS, Carr MD
Crystal structure of the human astrovirus capsid spike.
1. Proc Natl Acad Sci U S A - published August 2, 2011
2. Y Tao, E Méndez, L Dong, J Dong
Structure of Golgi Transport Proteins.
1. Cold Spring Harb Perspect Biol - published August 2, 2011
2. KM Reinisch, D Kümmel
The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections.
1. Proc Natl Acad Sci U S A - published August 2, 2011
2. Kornmann B, Osman C, Walter P
Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
1. Proc Natl Acad Sci U S A - published August 2, 2011
2. Rocha R, Pereira PJ, Santos MA, Macedo-Ribeiro S
Multiple ligand-specific conformations of the β2-adrenergic receptor.
1. Nat Chem Biol - published August 2, 2011
2. Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.
1. Nature - published August 2, 2011
2. Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ
Structure of a Light-Activated LOV Protein Dimer That Regulates Transcription.
1. Sci Signal - published August 2, 2011
2. BR Crane, JJ Loros, JC Dunlap, CH Chen, AT Vaidya
Mechanism of actin filament nucleation by the bacterial effector VopL.
1. Nat Struct Mol Biol - published August 2, 2011
2. Yu B, Cheng HC, Brautigam CA, Tomchick DR, Rosen MK
Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression.
1. Sci Signal - published August 2, 2011
2. Cooper J, Li W, You L, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG
Inducing phase changes in crystals of macromolecules: status and perspectives for controlled crystal dehydration.
1. J Struct Biol - published August 1, 2011
2. Russi S, Juers DH, Sanchez-Weatherby J, Pellegrini E, Mossou E, Forsyth VT, Huet J, Gobbo A, Felisaz F, Moya R, McSweeney SM, Cusack S, Cipriani F, Bowler MW
Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
1. J Virol - published August 1, 2011
2. McLellan JS, Yang Y, Graham BS, Kwong PD
Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.
1. Proteins - published August 1, 2011
2. Boto AN, Xu W, Jakoncic J, Pannuri A, Romeo T, Bessman MJ, Gabelli SB, Amzel LM
Structure of the HIV-1 frameshift site RNA bound to a small molecule inhibitor of viral replication.
1. ACS Chem Biol - published August 1, 2011
2. Marcheschi RJ, Tonelli M, Kumar A, Butcher SE
Crystal structure of the Pseudomonas aeruginosa virulence factor regulator.
1. J Bacteriol - published August 1, 2011
2. Cordes TJ, Worzalla GA, Ginster AM, Forest KT
Importance of a hydrophobic pocket for peptide binding in lactococcal OppA.
1. J Bacteriol - published August 1, 2011
2. Berntsson RP, Thunnissen AM, Poolman B, Slotboom DJ
Importin-alpha protein binding to a nuclear localization signal of carbohydrate response element-binding protein (ChREBP).
1. J Biol Chem - published August 1, 2011
2. Ge Q, Nakagawa T, Wynn RM, Chook YM, Miller BC, Uyeda K
The RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation.
1. Mol Cell Biol - published August 1, 2011
2. Palangat M, Grass JA, Langelier MF, Coulombe B, Landick R
Arp2/3 complex is bound and activated by two WASP proteins.
1. Proc Natl Acad Sci U S A - published August 1, 2011
2. Padrick SB, Doolittle LK, Brautigam CA, King DS, Rosen MK
Kinesin Kar3Cik1 ATPase pathway for microtubule cross-linking.
1. J Biol Chem - published August 1, 2011
2. Chen CJ, Rayment I, Gilbert SP
A minimal nuclear localization signal (NLS) in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin alpha1.
1. J Biol Chem - published August 1, 2011
2. Lott K, Bhardwaj A, Sims PJ, Cingolani G
Activities of human RRP6 and structure of the human RRP6 catalytic domain.
1. RNA - published August 1, 2011
2. Januszyk K, Liu Q, Lima CD
RNA transcript 3'-proximal sequence affects translocation bias of RNA polymerase.
1. Biochemistry - published August 1, 2011
2. Hein PP, Palangat M, Landick R
Comparing signaling networks between normal and transformed hepatocytes using discrete logical models.
1. Cancer Res - published August 1, 2011
2. Saez-Rodriguez J, Alexopoulos LG, Zhang M, Morris MK, Lauffenburger DA, Sorger PK
High-Throughput Quantification of Bioactive Lipids by MALDI Mass Spectrometry: Application to Prostaglandins.
1. Anal Chem - published August 1, 2011
2. LJ Marnett, CD Weaver, JC Latham, ML Reyzer, JD Manna, RM Caprioli
EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins.
1. Proc Natl Acad Sci U S A - published August 1, 2011
2. Rosenberg OS, Dovey C, Tempesta M, Robbins RA, Finer-Moore JS, Stroud RM, Cox JS
In silico identification and crystal structure validation of caspase-3 inhibitors without a P1 aspartic acid moiety.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published August 1, 2011
2. Ganesan R, Jelakovic S, Mittl PR, Caflisch A, Grütter MG
Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSβ.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published August 1, 2011
2. LS Beese, PL Modrich, A Changela, RR Iyer, MA Hast, J Orans, Q Tseng
Structural basis for the Trembler-J phenotype of Charcot-Marie-Tooth disease.
1. Structure - published August 1, 2011
2. Sakakura M, Hadziselimovic A, Wang Z, Schey KL, Sanders CR
Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.
1. Neuron - published August 1, 2011
2. Matsuoka RL, Chivatakarn O, Badea TC, Samuels IS, Cahill H, Katayama K, Kumar SR, Suto F, Chédotal A, Peachey NS, Nathans J, Yoshida Y, Giger RJ, Kolodkin AL
Actin dynamics counteract membrane tension during clathrin-mediated endocytosis.
1. Nat Cell Biol - published August 1, 2011
2. Boulant S, Kural C, Zeeh JC, Ubelmann F, Kirchhausen T
Automated real-space refinement of protein structures using a realistic backbone move set.
1. Biophys J - published August 1, 2011
2. Haddadian EJ, Gong H, Jha AK, Yang X, Debartolo J, Hinshaw JR, Rice PA, Sosnick TR, Freed KF
An extended dsRBD with a novel zinc-binding motif mediates nuclear retention of fission yeast Dicer.
1. EMBO J - published August 1, 2011
2. Barraud P, Emmerth S, Shimada Y, Hotz HR, Allain FH, Bühler M
Mechanisms for the inheritance of chromatin states.
1. Cell - published August 1, 2011
2. Moazed D
Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).
1. PLoS Pathog - published August 1, 2011
2. Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M
Quasi-Biomimetic Ring Contraction Catalyzed by a Cysteine-Based Nucleophile: Total Synthesis of Sch-642305, Some Analogs and their Putative anti-HIV Activities.
1. Chem Sci - published August 1, 2011
2. Dermenci A, Selig PS, Domaoal RA, Spasov KA, Anderson KS, Miller SJ
Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity.
1. ACS Med Chem Lett - published August 1, 2011
2. Lukkarila JL, da Silva SR, Ali M, Shahani VM, Xu GW, Berman J, Roughton A, Dhe-Paganon S, Schimmer AD, Gunning PT