Member Publications

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42 Member Publications for May 2011

The Thr- and Ala-rich hyperactive antifreeze protein from inchworm folds as a flat silk-like β-helix.
1. Biochemistry - published May 31, 2011
2. LA Graham, PL Davies, FH Lin
Structural components and architectures of RNA exosomes.
1. Adv Exp Med Biol - published May 31, 2011
2. Januszyk K, Lima CD
The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization.
1. J Biol Chem - published May 27, 2011
2. K Luger, DD Winkler
Combinatorial readout of dual histone modifications by paired chromatin-associated modules.
1. J Biol Chem - published May 27, 2011
2. DJ Patel, Z Wang
Riboswitches: Discovery of Drugs That Target Bacterial Gene-Regulatory RNAs.
1. Acc Chem Res - published May 26, 2011
Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growth.
1. Virology - published May 25, 2011
2. E Johannsen, E Kieff, SC Blacklow, AM Holthaus, S Lee, MA Calderwood
Mapping E. coli RNA polymerase and associated transcription factors and identifying promoters genome-wide.
1. Methods Enzymol - published May 24, 2011
2. Davis SE, Mooney RA, Kanin EI, Grass J, Landick R, Ansari AZ
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development.
1. ACS Chem Biol - published May 20, 2011
2. JC Williams, D Horne, R Jove, Y Chen, R Yip, TD Lee, G Gugiu, R Moore, N Vaidehi, F Yakushijin, K Yakushijin, YC Yuan, H Li, J Yim, A Herrmann, A Mao, A Schroeder, M Hedvat, M Senthil, J Lin, R Rashid, R Corzano, R Buettner
Identification and optimization of small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells.
1. ACS Chem Biol - published May 20, 2011
2. CW Lindsley, RD Beauchamp, CD Weaver, S Brady, C Farmer, E Days, AG Waterson, C Weaver, AS Pearson, SL Stoops
Molecular structure and flexibility of the yeast coatomer as revealed by electron microscopy.
1. J Mol Biol - published May 20, 2011
2. T Walz, CK Yip
tmRNA on its way through the ribosome: two steps of resume, and what next?
1. RNA Biol - published May 20, 2011
2. Fu J, Hashem Y, Wower J, Frank J
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.
1. Nature - published May 19, 2011
2. A Rao, S Agarwal, PM Milos, JR Ecker, XS Liu, GQ Daley, M Tahiliani, P Kapranov, S Mahapatra, Y Brudno, EM McLoughlin, M Ko, R Lister, HR Henderson, Y Huang, UJ Pape, WA Pastor
Mapping the reaction coordinates of enzymatic defluorination.
1. J Am Chem Soc - published May 18, 2011
2. EF Pai, EA Edwards, AF Yakunin, PW Chan
Synaptosomes as a platform for loading nanoparticles into synaptic vesicles.
1. ACS Chem Neurosci - published May 18, 2011
2. DT Chiu, SM Bajjaleih, T Gonen, NG Shuart, JC Gadd, BS Fujimoto, AE Sgro, KL Budzinski
From structure--based to knowledge--based drug design through x-ray protein crystallography: sketching glycogen phosphorylase binding sites.
1. Curr Med Chem - published May 17, 2011
2. Chrysina ED, Chajistamatiou A, Chegkazi M
Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
1. J Immunol - published May 15, 2011
2. MM Davis, KC Garcia, MS Kuhns, AE Lin, SN Rodriguez, PA Reay, AC Kruse, LK Ely, EW Newell
Preserving the membrane barrier for small molecules during bacterial protein translocation.
1. Nature - published May 12, 2011
2. TA Rapoport, E Park
Sticking together: glycogen-degrading virulence.
1. Structure - published May 11, 2011
2. EA Bayer, SP Smith
The mechanism of peptidyl transfer catalysis by the ribosome.
1. Annu Rev Biochem - published May 10, 2011
2. Leung EK, Suslov N, Tuttle N, Sengupta R, Piccirilli JA
Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking.
1. FEBS Lett - published May 6, 2011
2. T Rapoport, P Carvalho, AM Stanley
Structure and assembly of the essential RNA ring component of a viral DNA packaging motor.
1. Proc Natl Acad Sci U S A - published May 3, 2011
2. F Ding, A Ke, S Grimes, PJ Jardine, DL Anderson, KR Rajashankar, W Zhao, C Lu
Anchored clathrate waters bind antifreeze proteins to ice.
1. Proc Natl Acad Sci U S A - published May 3, 2011
2. PL Davies, RL Campbell, CP Garnham
Structure-function analysis of the C-terminal domain of CNM67, a core component of the Saccharomyces cerevisiae spindle pole body.
1. J Biol Chem - published May 2, 2011
2. Klenchin VA, Frye JJ, Jones MH, Winey M, Rayment I
Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonists.
1. Bioorg Med Chem Lett - published May 1, 2011
New ligation-independent cloning vectors compatible with a high-throughput platform for parallel construct expression evaluation using baculovirus-infected insect cells.
1. Protein Expr Purif - published May 1, 2011
2. Brown WC, DelProposto J, Rubin JR, Lamiman K, Carless J, Smith JL
Designed ankyrin repeat protein binders for the crystallization of AcrB: plasticity of the dominant interface.
1. J Struct Biol - published May 1, 2011
2. Monroe N, Sennhauser G, Seeger MA, Briand C, Grütter MG
Immunotypes of a quaternary site of HIV-1 vulnerability and their recognition by antibodies.
1. J Virol - published May 1, 2011
2. Wu X, Changela A, O'Dell S, Schmidt SD, Pancera M, Yang Y, Zhang B, Gorny MK, Phogat S, Robinson JE, Stamatatos L, Zolla-Pazner S, Kwong PD, Mascola JR
Unmasking the active helicase conformation of nonstructural protein 3 from hepatitis C virus.
1. J Virol - published May 1, 2011
2. Ding SC, Kohlway AS, Pyle AM
Removal of lactate dehydrogenase-elevating virus from human-in-mouse breast tumor xenografts by cell-sorting.
1. J Virol Methods - published May 1, 2011
2. Liu H, Bockhorn J, Dalton R, Chang YF, Qian D, Zitzow LA, Clarke MF, Greene GL
Bayesian estimation of NMR restraint potential and weight: a validation on a representative set of protein structures.
1. Proteins - published May 1, 2011
2. Bernard A, Vranken WF, Bardiaux B, Nilges M, Malliavin TE
Molecular dynamics of EF-G during translocation.
1. Proteins - published May 1, 2011
2. Li W, Trabuco LG, Schulten K, Frank J
Evolution of three human GPCRs for higher expression and stability.
1. J Mol Biol - published May 1, 2011
2. Dodevski I, Plückthun A
Conformational dynamics of the molecular chaperone Hsp90.
1. Q Rev Biophys - published May 1, 2011
2. Krukenberg KA, Street TO, Lavery LA, Agard DA
Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor.
1. J Biol Chem - published May 1, 2011
2. Waters LC, Strong SL, Ferlemann E, Oka O, Muskett FW, Veverka V, Banerjee S, Schmedt T, Henry AJ, Klempnauer KH, Carr MD
Translation calibration of inverse-kappa goniometers in macromolecular crystallography.
1. Acta Crystallogr A - published May 1, 2011
2. Brockhauser S, White KI, McCarthy AA, Ravelli RB
M-ficolin interacts with the long pentraxin PTX3: a novel case of cross-talk between soluble pattern-recognition molecules.
1. J Immunol - published May 1, 2011
2. Gout E, Moriscot C, Doni A, Dumestre-Pérard C, Lacroix M, Pérard J, Schoehn G, Mantovani A, Arlaud GJ, Thielens NM
ARFGAP1 promotes AP-2-dependent endocytosis.
1. Nat Cell Biol - published May 1, 2011
2. Bai M, Gad H, Turacchio G, Cocucci E, Yang JS, Li J, Beznoussenko GV, Nie Z, Luo R, Fu L, Collawn JF, Kirchhausen T, Luini A, Hsu VW
Exocyst function is regulated by effector phosphorylation.
1. Nat Cell Biol - published May 1, 2011
2. Chen XW, Leto D, Xiao J, Goss J, Wang Q, Shavit JA, Xiong T, Yu G, Ginsburg D, Toomre D, Xu Z, Saltiel AR
Equilibrium distribution from distributed computing (simulations of protein folding).
1. J Phys Chem B - published May 1, 2011
2. Scalco R, Caflisch A
Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design.
1. Proc Natl Acad Sci U S A - published May 1, 2011
2. Gilbreth RN, Truong K, Madu I, Koide A, Wojcik JB, Li NS, Piccirilli JA, Chen Y, Koide S
Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published May 1, 2011
2. Amacher JF, Cushing PR, Weiner JA, Madden DR
A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
1. Biophys J - published May 1, 2011
2. Cordero-Morales JF, Jogini V, Chakrapani S, Perozo E