Member Publications

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52 Member Publications for April 2011

Structure and mechanism of the chromatin remodelling factor ISW1a.
1. Nature - published April 28, 2011
Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells.
1. Immunity - published April 22, 2011
Strategies for Neoglycan conjugation to human acid α-glucosidase.
1. Bioconjug Chem - published April 20, 2011
N-terminal domain of alphaB-crystallin provides a conformational switch for multimerization and structural heterogeneity.
1. Proc Natl Acad Sci U S A - published April 19, 2011
Structural basis for the inhibition of human alkyladenine DNA glycosylase (AAG) by 3,N4-ethenocytosine-containing DNA.
1. J Biol Chem - published April 15, 2011
Wide prevalence of heterosubtypic broadly neutralizing human anti-influenza A antibodies.
1. Clin Infect Dis - published April 15, 2011
Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family.
1. Cell - published April 15, 2011
Structural insights into radical generation by the radical SAM superfamily.
1. Chem Rev - published April 13, 2011
Reintroducing electrostatics into macromolecular crystallographic refinement: application to neutron crystallography and DNA hydration.
1. Structure - published April 13, 2011
Membrane protein structure determination using paramagnetic tags.
1. Structure - published April 13, 2011
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas.
1. J Exp Med - published April 11, 2011
A dominant-negative Galpha mutant that traps a stable rhodopsin-Galpha-GTP-betagamma complex.
1. J Biol Chem - published April 8, 2011
2. Ramachandran S, Cerione RA
Structural variations within the transferrin binding site on transferrin-binding protein B, TbpB.
1. J Biol Chem - published April 8, 2011
2. Calmettes C, Yu RH, Silva LP, Curran D, Schriemer DC, Schryvers AB, Moraes TF
Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms.
1. Mol Cell - published April 8, 2011
2. Jura N, Zhang X, Endres NF, Seeliger MA, Schindler T, Kuriyan J
Substrate binding drives large-scale conformational changes in the Hsp90 molecular chaperone.
1. Mol Cell - published April 8, 2011
2. Street TO, Lavery LA, Agard DA
A conserved role for SNX9-family members in the regulation of phagosome maturation during engulfment of apoptotic cells.
1. PLoS One - published April 8, 2011
2. Almendinger J, Doukoumetzidis K, Kinchen JM, Kaech A, Ravichandran KS, Hengartner MO
Molecular structures and interactions in the yeast kinetochore.
1. Cold Spring Harb Symp Quant Biol - published April 7, 2011
2. Cho US, Corbett KD, Al-Bassam J, Bellizzi JJ 3rd, De Wulf P, Espelin CW, Miranda JJ, Simons K, Wei RR, Sorger PK, Harrison SC
"Molecular switches" on mGluR allosteric ligands that modulate modes of pharmacology.
1. Biochemistry - published April 5, 2011
Putting the brakes on the unfolded protein response.
1. J Cell Biol - published April 4, 2011
2. Sicheri F, Silverman RH
Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity.
1. J Cell Biol - published April 4, 2011
2. Rubio C, Pincus D, Korennykh A, Schuck S, El-Samad H, Walter P
RAC3 is a pro-migratory co-activator of ERα.
1. Oncogene - published April 2, 2011
2. Walker MP, Zhang M, Le TP, Wu P, Lainé M, Greene GL
Structure and binding mechanism of vascular endothelial cadherin: a divergent classical cadherin.
1. J Mol Biol - published April 2, 2011
2. Brasch J, Harrison OJ, Ahlsen G, Carnally SM, Henderson RM, Honig B, Shapiro L
Architecture and assembly of a divergent member of the ParM family of bacterial actin-like proteins.
1. J Biol Chem - published April 2, 2011
2. Rivera CR, Kollman JM, Polka JK, Agard DA, Mullins RD
Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase.
1. J Biol Chem - published April 2, 2011
2. Gehret JJ, Gu L, Gerwick WH, Wipf P, Sherman DH, Smith JL
Structural and biochemical characterization of NarE, an iron-containing ADP-ribosyltransferase from Neisseria meningitidis.
1. J Biol Chem - published April 2, 2011
2. Koehler C, Carlier L, Veggi D, Balducci E, Di Marcello F, Ferrer-Navarro M, Pizza M, Daura X, Soriani M, Boelens R, Bonvin AM
Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication.
1. Virology - published April 2, 2011
2. Lindquist ME, Mainou BA, Dermody TS, Crowe JE Jr
The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1.
1. J Biol Chem - published April 2, 2011
2. Syeda F, Fagan RL, Wean M, Avvakumov GV, Walker JR, Xue S, Dhe-Paganon S, Brenner C
Long helical filaments are not seen encircling cells in electron cryotomograms of rod-shaped bacteria.
1. Biochem Biophys Res Commun - published April 2, 2011
2. Swulius MT, Chen S, Jane Ding H, Li Z, Briegel A, Pilhofer M, Tocheva EI, Lybarger SR, Johnson TL, Sandkvist M, Jensen GJ
Aryl Extensions of Thienopyrimidinones as Fibroblast Growth Factor Receptor 1 Kinase Inhibitors.
1. Tetrahedron Lett - published April 2, 2011
2. Ekkati AR, Madiyan V, Ravindranathan KP, H Bae J, Schlessinger J, Jorgensen WL
NMR resonance assignments of NarE, a putative ADP-ribosylating toxin from Neisseria meningitidis.
1. Biomol NMR Assign - published April 1, 2011
2. Carlier L, Koehler C, Veggi D, Pizza M, Soriani M, Boelens R, Bonvin AM
Self-aligning amelogenin nanoribbons in oil-water system.
1. J Struct Biol - published April 1, 2011
2. He X, Wu S, Martinez-Avila O, Cheng Y, Habelitz S
ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary.
1. Exp Cell Res - published April 1, 2011
2. Congleton J, Jiang H, Malavasi F, Lin H, Yen A
Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel.
1. Curr Opin Struct Biol - published April 1, 2011
2. Van Horn WD, Vanoye CG, Sanders CR
Expanding the nucleotide and sugar 1-phosphate promiscuity of nucleotidyltransferase RmlA via directed evolution.
1. J Biol Chem - published April 1, 2011
2. Moretti R, Chang A, Peltier-Pain P, Bingman CA, Phillips GN Jr, Thorson JS
Oxidative modifications of the C-terminal domain of tropoelastin prevent cell binding.
1. J Biol Chem - published April 1, 2011
2. Akhtar K, Broekelmann TJ, Song H, Turk J, Brett TJ, Mecham RP, Adair-Kirk TL
Coupling efficiency of rhodopsin and transducin in bicelles.
1. Biochemistry - published April 1, 2011
2. Kaya AI, Thaker TM, Preininger AM, Iverson TM, Hamm HE
The structural basis for MCM2-7 helicase activation by GINS and Cdc45.
1. Nat Struct Mol Biol - published April 1, 2011
2. Costa A, Ilves I, Tamberg N, Petojevic T, Nogales E, Botchan MR, Berger JM
Structure and VP16 binding of the Mediator Med25 activator interaction domain.
1. Nat Struct Mol Biol - published April 1, 2011
2. Vojnic E, Mourão A, Seizl M, Simon B, Wenzeck L, Larivière L, Baumli S, Baumgart K, Meisterernst M, Sattler M, Cramer P
Structure of the C-terminal heme-binding domain of THAP domain containing protein 4 from Homo sapiens.
1. Proteins - published April 1, 2011
2. Bianchetti CM, Bingman CA, Phillips GN Jr
Structural architecture of Galdieria sulphuraria DCN1L.
1. Proteins - published April 1, 2011
2. Sethe Burgie E, Bingman CA, Makino S, Wesenberg GE, Pan X, Fox BG, Phillips GN Jr
Artesunate enhances the antibacterial effect of {beta}-lactam antibiotics against Escherichia coli by increasing antibiotic accumulation via inhibition of the multidrug efflux pump system AcrAB-TolC.
1. J Antimicrob Chemother - published April 1, 2011
2. Li B, Yao Q, Pan XC, Wang N, Zhang R, Li J, Ding G, Liu X, Wu C, Ran D, Zheng J, Zhou H
Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-β1.
1. Nat Struct Mol Biol - published April 1, 2011
2. Cléry A, Jayne S, Benderska N, Dominguez C, Stamm S, Allain FH
Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant T cells.
1. J Immunol - published April 1, 2011
2. Chua WJ, Kim S, Myers N, Huang S, Yu L, Fremont DH, Diamond MS, Hansen TH
Proteases as therapeutics.
1. Biochem J - published April 1, 2011
2. Craik CS, Page MJ, Madison EL
A versatile and efficient high-throughput cloning tool for structural biology.
1. Biochemistry - published April 1, 2011
2. Geertsma ER, Dutzler R
The ribotoxin restrictocin recognizes its RNA substrate by selective engagement of active site residues.
1. Biochemistry - published April 1, 2011
2. Plantinga MJ, Korennykh AV, Piccirilli JA, Correll CC
Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics.
1. J Am Chem Soc - published April 1, 2011
2. Zhang W, Ntai I, Bolla ML, Malcolmson SJ, Kahne D, Kelleher NL, Walsh CT
Structural analysis of large protein complexes using solvent paramagnetic relaxation enhancements.
1. Angew Chem Int Ed Engl - published April 1, 2011
2. Madl T, Güttler T, Görlich D, Sattler M
A multidomain flexible docking approach to deal with large conformational changes in the modeling of biomolecular complexes.
1. Structure - published April 1, 2011
2. Karaca E, Bonvin AM
Septin filament formation is essential in budding yeast.
1. Dev Cell - published April 1, 2011
2. McMurray MA, Bertin A, Garcia G 3rd, Lam L, Nogales E, Thorner J
A cytoplasmic complex mediates specific mRNA recognition and localization in yeast.
1. PLoS Biol - published April 1, 2011
2. Müller M, Heym RG, Mayer A, Kramer K, Schmid M, Cramer P, Urlaub H, Jansen RP, Niessing D
A comparison of the anti-tumor effects of a chimeric versus murine anti-CD19 immunotoxins on human B cell lymphoma and Pre-B acute lymphoblastic leukemia cell lines.
1. Toxins (Basel) - published April 1, 2011
2. Tsai LK, Pop LM, Liu X, Vitetta ES