Member Publications

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59 Member Publications for February 2011

Construction of a thiamin sensor from the periplasmic thiamin binding protein.
1. Chem Commun (Camb) - published February 28, 2011
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
1. Science - published February 25, 2011
Discovery, synthesis, and structure-activity relationship development of a series of N-(4-acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)) with CNS exposure in rats.
1. J Med Chem - published February 24, 2011
Graphene structures at an extreme degree of buckling.
1. ACS Nano - published February 22, 2011
Derepression of bacterial transcription-repair coupling factor is associated with a profound conformational change.
1. J Mol Biol - published February 18, 2011
Membrane-coating lattice scaffolds in the nuclear pore and vesicle coats: commonalities, differences, challenges.
1. Nucleus - published February 18, 2011
2. Leksa NC, Schwartz TU
The crystal structure of the signal recognition particle in complex with its receptor.
1. Science - published February 18, 2011
A fluorescence polarization assay using an engineered human respiratory syncytial virus F protein as a direct screening platform.
1. Anal Biochem - published February 15, 2011
Numb is a negative regulator of HGF dependent cell scattering and Rac1 activation.
1. Exp Cell Res - published February 15, 2011
Toxoflavin lyase requires a novel 1-His-2-carboxylate facial triad.
1. Biochemistry - published February 15, 2011
Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin.
1. Mol Biol Cell - published February 15, 2011
The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation.
1. J Immunol - published February 15, 2011
Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5.
1. J Mol Biol - published February 11, 2011
Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1.
1. Science - published February 11, 2011
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension.
1. Science - published February 11, 2011
An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
1. mBio - published February 10, 2011
2. Krause JC, Ekiert DC, Tumpey TM, Smith PB, Wilson IA, Crowe JE Jr
Two distinct mechanisms for TIM barrel prenyltransferases in bacteria.
1. J Am Chem Soc - published February 9, 2011
2. Doud EH, Perlstein DL, Wolpert M, Cane DE, Walker S
Structural basis of Streptococcus pyogenes immunity to its NAD+ glycohydrolase toxin.
1. Structure - published February 9, 2011
2. Smith CL, Ghosh J, Elam JS, Pinkner JS, Hultgren SJ, Caparon MG, Ellenberger T
Cross-crystal averaging with search models to improve molecular replacement phases.
1. Structure - published February 9, 2011
2. Li W, Li F
The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.
1. Structure - published February 9, 2011
2. Harrison OJ, Jin X, Hong S, Bahna F, Ahlsen G, Brasch J, Wu Y, Vendome J, Felsovalyi K, Hampton CM, Troyanovsky RB, Ben-Shaul A, Frank J, Troyanovsky SM, Shapiro L, Honig B
Molecular architecture of TylM1 from Streptomyces fradiae: an N,N-dimethyltransferase involved in the production of dTDP-D-mycaminose.
1. Biochemistry - published February 8, 2011
2. Carney AE, Holden HM
Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A.
1. Proc Natl Acad Sci U S A - published February 8, 2011
The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel.
1. Proc Natl Acad Sci U S A - published February 8, 2011
Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP).
1. Phys Chem Chem Phys - published February 7, 2011
2. Hoffmann A, Nettels D, Clark J, Borgia A, Radford SE, Clarke J, Schuler B
Human DNA polymerase beta mutations allowing efficient abasic site bypass.
1. J Biol Chem - published February 4, 2011
2. Gieseking S, Bergen K, Di Pasquale F, Diederichs K, Welte W, Marx A
A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.
1. J Biol Chem - published February 4, 2011
The structural basis for tight control of PP2A methylation and function by LCMT-1.
1. Mol Cell - published February 4, 2011
2. Stanevich V, Jiang L, Satyshur KA, Li Y, Jeffrey PD, Li Z, Menden P, Semmelhack MF, Xing Y
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
1. Cell Stem Cell - published February 4, 2011
Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites.
1. Cell - published February 4, 2011
Ubiquitin is a novel substrate for human insulin-degrading enzyme.
1. J Mol Biol - published February 2, 2011
2. Ralat LA, Kalas V, Zheng Z, Goldman RD, Sosnick TR, Tang WJ
Proteins of the innate immune system crystallize on carbon nanotubes but are not activated.
1. ACS Nano - published February 2, 2011
2. Ling WL, Biro A, Bally I, Tacnet P, Deniaud A, Doris E, Frachet P, Schoehn G, Pebay-Peyroula E, Arlaud GJ
Dual-mode phospholipid regulation of human inward rectifying potassium channels.
1. Biophys J - published February 2, 2011
2. Cheng WWL, D'Avanzo N, Doyle DA, Nichols CG
Significance testing as perverse probabilistic reasoning.
1. BMC Med - published February 2, 2011
2. Westover MB, Westover KD, Bianchi MT
Structure characterization of the 26S proteasome.
1. Biochim Biophys Acta - published February 1, 2011
2. Kim HM, Yu Y, Cheng Y
Conformational dynamics of supramolecular protein assemblies.
1. J Struct Biol - published February 1, 2011
2. Kim DN, Nguyen CT, Bathe M
Over-expression of microRNA169 confers enhanced drought tolerance to tomato.
1. Biotechnol Lett - published February 1, 2011
2. Zhang X, Zou Z, Gong P, Zhang J, Ziaf K, Li H, Xiao F, Ye Z
The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.
1. J Pharmacol Exp Ther - published February 1, 2011
2. Maciag AE, Chakrapani H, Saavedra JE, Morris NL, Holland RJ, Kosak KM, Shami PJ, Anderson LM, Keefer LK
A minimal Rac activation domain in the unconventional guanine nucleotide exchange factor Dock180.
1. Biochemistry - published February 1, 2011
2. Wu X, Ramachandran S, Lin MC, Cerione RA, Erickson JW
Human galectin-3 (Mac-2 antigen): defining molecular switches of affinity to natural glycoproteins, structural and dynamic aspects of glycan binding by flexible ligand docking and putative regulatory sequences in the proximal promoter region.
1. Biochim Biophys Acta - published February 1, 2011
2. Krzeminski M, Singh T, André S, Lensch M, Wu AM, Bonvin AM, Gabius HJ
Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2.
1. J Biol Chem - published February 1, 2011
2. Shloush J, Vlassov JE, Engson I, Duan S, Saridakis V, Dhe-Paganon S, Raught B, Sheng Y, Arrowsmith CH
Quaternary structure and functional unit of energy coupling factor (ECF)-type transporters.
1. J Biol Chem - published February 1, 2011
2. ter Beek J, Duurkens RH, Erkens GB, Slotboom DJ
Loop L5 acts as a conformational latch in the mitotic kinesin Eg5.
1. J Biol Chem - published February 1, 2011
2. Behnke-Parks WM, Vendome J, Honig B, Maliga Z, Moores C, Rosenfeld SS
The folding of single domain proteins--have we reached a consensus?
1. Curr Opin Struct Biol - published February 1, 2011
2. Sosnick TR, Barrick D
Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition.
1. RNA - published February 1, 2011
2. Borja MS, Piotukh K, Freund C, Gross JD
The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule.
1. Mol Biol Cell - published February 1, 2011
2. Ramey VH, Wang HW, Nakajima Y, Wong A, Liu J, Drubin D, Barnes G, Nogales E
Global gene expression patterns in Clostridium thermocellum as determined by microarray analysis of chemostat cultures on cellulose or cellobiose.
1. Appl Environ Microbiol - published February 1, 2011
2. Riederer A, Takasuka TE, Makino S, Stevenson DM, Bukhman YV, Elsen NL, Fox BG
HDAC3-dependent reversible lysine acetylation of cardiac myosin heavy chain isoforms modulates their enzymatic and motor activity.
1. J Biol Chem - published February 1, 2011
2. Samant SA, Courson DS, Sundaresan NR, Pillai VB, Tan M, Zhao Y, Shroff SG, Rock RS, Gupta MP
Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires.
1. J Immunol - published February 1, 2011
Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1.
1. Nat Struct Mol Biol - published February 1, 2011
2. Kadlec J, Hallacli E, Lipp M, Holz H, Sanchez-Weatherby J, Cusack S, Akhtar A
Evidence for the presence of a critical disulfide bond in the mouse EP3γ receptor.
1. Prostaglandins Other Lipid Mediat - published February 1, 2011
2. Downey JD, Sanders CR, Breyer RM
Structure determination and dynamics of protein-RNA complexes by NMR spectroscopy.
1. Prog Nucl Magn Reson Spectrosc - published February 1, 2011
2. Dominguez C, Schubert M, Duss O, Ravindranathan S, Allain FH
Structure of the minor pseudopilin XcpW from the Pseudomonas aeruginosa type II secretion system.
1. Acta Crystallogr D Biol Crystallogr - published February 1, 2011
2. Franz LP, Douzi B, Durand E, Dyer DH, Voulhoux R, Forest KT
Bacterial phytochromes: more than meets the light.
1. Crit Rev Biochem Mol Biol - published February 1, 2011
2. Auldridge ME, Forest KT
Purification, crystallization and preliminary crystallographic analysis of the SH2 domain of IL-2-inducible T-cell kinase.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published February 1, 2011
2. Joseph RE, Ginder ND, Hoy JA, Nix JC, Honzatko RB, Andreotti AH
Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis.
1. PLoS Biol - published February 1, 2011
Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.
1. PLoS Genet - published February 1, 2011
2. Kuchtey J, Olson LM, Rinkoski T, Mackay EO, Iverson TM, Gelatt KN, Haines JL, Kuchtey RW
The free energy landscape of small molecule unbinding.
1. PLoS Comput Biol - published February 1, 2011
2. Huang D, Caflisch A
Y95 and E444 interaction required for high-affinity S-citalopram binding in the human serotonin transporter.
1. ACS Chem Neurosci - published February 1, 2011
2. Combs S, Kaufmann K, Field JR, Blakely RD, Meiler J
bcl::Cluster : A method for clustering biological molecules coupled with visualization in the Pymol Molecular Graphics System.
1. IEEE Int Conf Comput Adv Bio Med Sci - published February 1, 2011
2. Alexander N, Woetzel N, Meiler J