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52 Member Publications for January 2011

Autophosphorylation activates Dictyostelium myosin II heavy chain kinase A by providing a ligand for an allosteric binding site in the alpha-kinase domain.
1. J Biol Chem - published January 28, 2011
Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
1. J Biol Chem - published January 28, 2011
Principles of IRE1 modulation using chemical tools.
1. Methods Enzymol - published January 27, 2011
2. Lee KP, Sicheri F
Heterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant.
1. PLoS One - published January 26, 2011
Synthetic lethal compound combinations reveal a fundamental connection between wall teichoic acid and peptidoglycan biosyntheses in Staphylococcus aureus.
1. ACS Chem Biol - published January 21, 2011
Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
1. Proc Natl Acad Sci U S A - published January 18, 2011
Thrombin as an anticoagulant.
1. Prog Mol Biol Transl Sci - published January 18, 2011
2. Di Cera E
A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC.
1. J Exp Med - published January 17, 2011
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
1. Genes Dev - published January 15, 2011
Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex.
1. Structure - published January 12, 2011
The oligopeptidase B of Leishmania regulates parasite enolase and immune evasion.
1. J Biol Chem - published January 7, 2011
2. Swenerton RK, Zhang S, Sajid M, Medzihradszky KF, Craik CS, Kelly BL, McKerrow JH
Structure of precursor-bound NifEN: a nitrogenase FeMo cofactor maturase/insertase.
1. Science - published January 7, 2011
Crystal structure of Escherichia coli CusC, the outer membrane component of a heavy metal efflux pump.
1. PLoS One - published January 7, 2011
Structural and thermodynamic analysis of PDZ-ligand interactions.
1. Methods Enzymol - published January 4, 2011
2. Shepherd TR, Fuentes EJ
Characterization of a core fragment of the rhesus monkey TRIM5α protein.
1. BMC Biochem - published January 4, 2011
Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling.
1. Vision Res - published January 2, 2011
2. Badea TC, Nathans J
Structural and biophysical analysis of BST-2/tetherin ectodomains reveals an evolutionary conserved design to inhibit virus release.
1. J Biol Chem - published January 2, 2011
2. Swiecki M, Scheaffer SM, Allaire M, Fremont DH, Colonna M, Brett TJ
Solution structure and activation mechanism of ubiquitin-like small archaeal modifier proteins.
1. J Mol Biol - published January 2, 2011
2. Ranjan N, Damberger FF, Sutter M, Allain FH, Weber-Ban E
A hybrid structural model of the complete Brugia malayi cytoplasmic asparaginyl-tRNA synthetase.
1. J Mol Biol - published January 2, 2011
2. Crepin T, Peterson F, Haertlein M, Jensen D, Wang C, Cusack S, Kron M
Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry.
1. Proc Natl Acad Sci U S A - published January 2, 2011
2. Zheng L, Stathopulos PB, Schindl R, Li GY, Romanin C, Ikura M
Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
1. Nature - published January 2, 2011
2. Lazarus MB, Nam Y, Jiang J, Sliz P, Walker S
Peptide length and leaving-group sterics influence potency of peptide phosphonate protease inhibitors.
1. Chem Biol - published January 2, 2011
2. Brown CM, Ray M, Eroy-Reveles AA, Egea P, Tajon C, Craik CS
Welcome to skeletal muscle.
1. Skelet Muscle - published January 2, 2011
2. Glass DJ, Campbell KP, Rudnicki MA
Fibrella aestuarina gen. nov., sp. nov., a filamentous bacterium of the family Cytophagaceae isolated from a tidal flat, and emended description of the genus Rudanella Weon et al. 2008.
1. Int J Syst Evol Microbiol - published January 1, 2011
2. Filippini M, Svercel M, Laczko E, Kaech A, Ziegler U, Bagheri HC
Mechanism of substrate specificity in 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases.
1. J Struct Biol - published January 1, 2011
2. Siu KK, Asmus K, Zhang AN, Horvatin C, Li S, Liu T, Moffatt B, Woods VL Jr, Howell PL
Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies.
1. Methods - published January 1, 2011
2. Pagans S, Sakane N, Schnölzer M, Ott M
An MRI-based atlas and database of the developing mouse brain.
1. Neuroimage - published January 1, 2011
2. Chuang N, Mori S, Yamamoto A, Jiang H, Ye X, Xu X, Richards LJ, Nathans J, Miller MI, Toga AW, Sidman RL, Zhang J
An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice.
1. Diabetologia - published January 1, 2011
2. Sadacca LA, Lamia KA, deLemos AS, Blum B, Weitz CJ
EMDataBank.org: unified data resource for CryoEM.
1. Nucleic Acids Res - published January 1, 2011
2. Lawson CL, Baker ML, Best C, Bi C, Dougherty M, Feng P, van Ginkel G, Devkota B, Lagerstedt I, Ludtke SJ, Newman RH, Oldfield TJ, Rees I, Sahni G, Sala R, Velankar S, Warren J, Westbrook JD, Henrick K, Kleywegt GJ, Berman HM, Chiu W
Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.
1. J Pathol - published January 1, 2011
2. Aster JC, Blacklow SC, Pear WS
A short note on the analysis of distance measurements by electron paramagnetic resonance.
1. J Magn Reson - published January 1, 2011
2. Domingo Köhler S, Spitzbarth M, Diederichs K, Exner TE, Drescher M
Conformational dynamics data bank: a database for conformational dynamics of proteins and supramolecular protein assemblies.
1. Nucleic Acids Res - published January 1, 2011
2. Kim DN, Altschuler J, Strong C, McGill G, Bathe M
Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting.
1. J Mol Biol - published January 1, 2011
2. Dreier B, Mikheeva G, Belousova N, Parizek P, Boczek E, Jelesarov I, Forrer P, Plückthun A, Krasnykh V
Dual targets guided screening and isolation of Kukoamine B as a novel natural anti-sepsis agent from traditional Chinese herb Cortex lycii.
1. Int Immunopharmacol - published January 1, 2011
2. Liu X, Zheng X, Long Y, Cao H, Wang N, Lu Y, Zhao K, Zhou H, Zheng J
A novel fusion toxin derived from an EpCAM-specific designed ankyrin repeat protein has potent antitumor activity.
1. Clin Cancer Res - published January 1, 2011
2. Martin-Killias P, Stefan N, Rothschild S, Plückthun A, Zangemeister-Wittke U
Structure of Sir2Tm bound to a propionylated peptide.
1. Protein Sci - published January 1, 2011
2. Bheda P, Wang JT, Escalante-Semerena JC, Wolberger C
EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity.
1. J Immunol - published January 1, 2011
2. Yun TJ, Harning EK, Giza K, Rabah D, Li P, Arndt JW, Luchetti D, Biamonte MA, Shi J, Lundgren K, Manning A, Kehry MR
Controlling the activity of the Tec kinase Itk by mutation of the phenylalanine gatekeeper residue.
1. Biochemistry - published January 1, 2011
2. Joseph RE, Andreotti AH
A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination.
1. Nat Struct Mol Biol - published January 1, 2011
2. Koldobskaya Y, Duguid EM, Shechner DM, Suslov NB, Ye J, Sidhu SS, Bartel DP, Koide S, Kossiakoff AA, Piccirilli JA
Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity.
1. Mol Microbiol - published January 1, 2011
2. Empadinhas N, Pereira PJ, Albuquerque L, Costa J, Sá-Moura B, Marques AT, Macedo-Ribeiro S, da Costa MS
Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS.
1. J Synchrotron Radiat - published January 1, 2011
2. Englich U, Kriksunov IA, Cerione RA, Cook MJ, Gillilan R, Gruner SM, Huang Q, Kim CU, Miller W, Nielsen S, Schuller D, Smith S, Szebenyi DM
Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA.
1. Proc Natl Acad Sci U S A - published January 1, 2011
2. Melero R, Rajagopalan S, Lázaro M, Joerger AC, Brandt T, Veprintsev DB, Lasso G, Gil D, Scheres SH, Carazo JM, Fersht AR, Valle M
Carbohydrate recognition and complement activation by rat ficolin-B.
1. Eur J Immunol - published January 1, 2011
2. Girija UV, Mitchell DA, Roscher S, Wallis R
On the structural basis of modal gating behavior in K(+) channels.
1. Nat Struct Mol Biol - published January 1, 2011
2. Chakrapani S, Cordero-Morales JF, Jogini V, Pan AC, Cortes DM, Roux B, Perozo E
Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites.
1. Proc Natl Acad Sci U S A - published January 1, 2011
2. Derebe MG, Sauer DB, Zeng W, Alam A, Shi N, Jiang Y
Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore.
1. Proc Natl Acad Sci U S A - published January 1, 2011
2. Derebe MG, Zeng W, Li Y, Alam A, Jiang Y
PRIDEViewer: a novel user-friendly interface to visualize PRIDE XML files.
1. Proteomics - published January 1, 2011
2. Medina-Aunon JA, Carazo JM, Albar JP
Crystallization of the nonameric small terminase subunit of bacteriophage P22.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published January 1, 2011
2. Roy A, Bhardwaj A, Cingolani G
Myoglobinuria and muscle pain are common in patients with limb-girdle muscular dystrophy 2I.
1. Neurology - published January 1, 2011
2. Mathews KD, Stephan CM, Laubenthal K, Winder TL, Michele DE, Moore SA, Campbell KP
Structure and function of an irreversible agonist-β(2) adrenoceptor complex.
1. Nature - published January 1, 2011
2. Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK
Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.
1. Nature - published January 1, 2011
2. Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, Steyaert J, Weis WI, Kobilka BK
Correlative light-electron microscopy.
1. Adv Protein Chem Struct Biol - published January 1, 2011
2. Hanein D, Volkmann N