Member Publications

Jump to specific year:

65 Member Publications for November 2010

The crystal structure of OprG from Pseudomonas aeruginosa, a potential channel for transport of hydrophobic molecules across the outer membrane.
1. PLoS One - published November 29, 2010
Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB.
1. Chem Biol - published November 24, 2010
Mechanisms determining the morphology of the peripheral ER.
1. Cell - published November 24, 2010
Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.
1. PLoS One - published November 24, 2010
The transcription factor Spn1 regulates gene expression via a highly conserved novel structural motif.
1. J Mol Biol - published November 19, 2010
Neutralizing Positive Charges at the Surface of a Protein Lowers Its Rate of Amide Hydrogen Exchange without Altering Its Structure or Increasing Its Thermostability.
1. J Am Chem Soc - published November 19, 2010
An unprecedented nucleic acid capture mechanism for excision of DNA damage.
1. Nature - published November 18, 2010
Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor.
1. Nature - published November 18, 2010
Domain organization in Candida glabrata THI6, a bifunctional enzyme required for thiamin biosynthesis in eukaryotes.
1. Biochemistry - published November 16, 2010
Assembly of a functional Machupo virus polymerase complex.
1. Proc Natl Acad Sci U S A - published November 16, 2010
Prion disease susceptibility is affected by beta-structure folding propensity and local side-chain interactions in PrP.
1. Proc Natl Acad Sci U S A - published November 16, 2010
Molecular architecture of the vesicular stomatitis virus RNA polymerase.
1. Proc Natl Acad Sci U S A - published November 16, 2010
A stapled p53 helix overcomes HDMX-mediated suppression of p53.
1. Cancer Cell - published November 16, 2010
Mechanistic biology in the next quarter century.
1. Mol Biol Cell - published November 15, 2010
Crystal Structures of Urate Bound Form of Xanthine Oxidoreductase: Substrate Orientation and Structure of the Key Reaction Intermediate.
1. J Am Chem Soc - published November 15, 2010
A preliminary report on my life in science.
1. Mol Biol Cell - published November 15, 2010
Structural and mechanistic studies on Klebsiella pneumoniae 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase.
1. J Biol Chem - published November 12, 2010
BH3-triggered structural reorganization drives the activation of proapoptotic BAX.
1. Mol Cell - published November 12, 2010
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.
1. Cell - published November 12, 2010
Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones.
1. J Med Chem - published November 11, 2010
Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR.
1. Structure - published November 10, 2010
Reconstitution of diphthine synthase activity in vitro.
1. Biochemistry - published November 9, 2010
2. Zhu X, Kim J, Su X, Lin H
CHOBIMALT: a cholesterol-based detergent.
1. Biochemistry - published November 9, 2010
2. Howell SC, Mittal R, Huang L, Travis B, Breyer RM, Sanders CR
Crystal structure of prethrombin-1.
1. Proc Natl Acad Sci U S A - published November 9, 2010
2. Chen Z, Pelc LA, Di Cera E
Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain.
1. Gene Expr Patterns - published November 9, 2010
2. Ye X, Smallwood P, Nathans J
Computational Study of the DNA-Binding Protein Helicobacter pylori NikR: The Role of Ni(2.).
1. J Chem Theory Comput - published November 9, 2010
2. Musiani F, Bertoša B, Magistrato A, Zambelli B, Turano P, Losasso V, Micheletti C, Ciurli S, Carloni P
NHE3 activity is dependent on direct phosphoinositide binding at the N terminus of its intracellular cytosolic region.
1. J Biol Chem - published November 5, 2010
2. Mohan S, Tse CM, Gabelli SB, Sarker R, Cha B, Fahie K, Nadella M, Zachos NC, Tu-Sekine B, Raben D, Amzel LM, Donowitz M
Solution structure and phospholipid interactions of the isolated voltage-sensor domain from KvAP.
1. J Mol Biol - published November 5, 2010
Immunodominant T cell determinants of aquaporin-4, the autoantigen associated with neuromyelitis optica.
1. PLoS One - published November 3, 2010
2. Nelson PA, Khodadoust M, Prodhomme T, Spencer C, Patarroyo JC, Varrin-Doyer M, Ho JD, Stroud RM, Zamvil SS
Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis .
1. Biochemistry - published November 2, 2010
2. Vey JL, Al-Mestarihi A, Hu Y, Funk MA, Bachmann BO, Iverson TM
Free energy surfaces from single-distance information.
1. J Phys Chem B - published November 2, 2010
2. Schuetz P, Wuttke R, Schuler B, Caflisch A
Capitalizing on tumor genotyping: towards the design of mutation specific inhibitors of phosphoinsitide-3-kinase.
1. Adv Enzyme Regul - published November 2, 2010
2. Gabelli SB, Duong-Ly KC, Brower ET, Amzel LM
Discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy.
1. J Am Chem Soc - published November 2, 2010
2. Baird NJ, Ludtke SJ, Khant H, Chiu W, Pan T, Sosnick TR
4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.
1. J Med Chem - published November 2, 2010
2. Cho YS, Borland M, Brain C, Chen CH, Cheng H, Chopra R, Chung K, Groarke J, He G, Hou Y, Kim S, Kovats S, Lu Y, O'Reilly M, Shen J, Smith T, Trakshel G, Vögtle M, Xu M, Xu M, Sung MJ
Mechanisms of macromolecular protease inhibitors.
1. Chembiochem - published November 2, 2010
2. Farady CJ, Craik CS
Structure and control of the actin regulatory WAVE complex.
1. Nature - published November 2, 2010
2. Chen Z, Borek D, Padrick SB, Gomez TS, Metlagel Z, Ismail AM, Umetani J, Billadeau DD, Otwinowski Z, Rosen MK
The bridge helix coordinates movements of modules in RNA polymerase.
1. BMC Biol - published November 2, 2010
2. Hein PP, Landick R
Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings.
1. Invest Ophthalmol Vis Sci - published November 1, 2010
2. Ufret-Vincenty RL, Aredo B, Liu X, McMahon A, Chen PW, Sun H, Niederkorn JY, Kedzierski W
Specific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets.
1. FASEB J - published November 1, 2010
2. Noujaim SF, Stuckey JA, Ponce-Balbuena D, Ferrer-Villada T, López-Izquierdo A, Pandit S, Calvo CJ, Grzeda KR, Berenfeld O, Chapula JA, Jalife J
An easy-to-use tool for planning and modeling a calorimetric titration.
1. Anal Biochem - published November 1, 2010
Strengths and weaknesses of data-driven docking in critical assessment of prediction of interactions.
1. Proteins - published November 1, 2010
2. de Vries SJ, Melquiond AS, Kastritis PL, Karaca E, Bordogna A, van Dijk M, Rodrigues JP, Bonvin AM
A lead discovery strategy driven by a comprehensive analysis of proteases in the peptide substrate space.
1. Protein Sci - published November 1, 2010
2. Sukuru SC, Nigsch F, Quancard J, Renatus M, Chopra R, Brooijmans N, Mikhailov D, Deng Z, Cornett A, Jenkins JL, Hommel U, Davies JW, Glick M
A fast, efficient and sequence-independent method for flexible multiple segmental isotope labeling of RNA using ribozyme and RNase H cleavage.
1. Nucleic Acids Res - published November 1, 2010
2. Duss O, Maris C, von Schroetter C, Allain FH
Neuroprotective effects of leptin following kainic acid-induced status epilepticus.
1. Epilepsy Behav - published November 1, 2010
2. Obeid M, Frank J, Medina M, Finckbone V, Bliss R, Bista B, Majmudar S, Hurst D, Strahlendorf H, Strahlendorf J
Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity.
1. J Biol Chem - published November 1, 2010
2. Ko S, Kang GB, Song SM, Lee JG, Shin DY, Yun JH, Sheng Y, Cheong C, Jeon YH, Jung YK, Arrowsmith CH, Avvakumov GV, Dhe-Paganon S, Yoo YJ, Eom SH, Lee W
Structural and kinetic analysis of Bacillus subtilis N-acetylglucosaminidase reveals a unique Asp-His dyad mechanism.
1. J Biol Chem - published November 1, 2010
2. Litzinger S, Fischer S, Polzer P, Diederichs K, Welte W, Mayer C
Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.
1. J Biol Chem - published November 1, 2010
2. Chan J, Yamazaki H, Ishiyama N, Seo MD, Mal TK, Michikawa T, Mikoshiba K, Ikura M
Sin resolvase catalytic activity and oligomerization state are tightly coupled.
1. J Mol Biol - published November 1, 2010
2. Mouw KW, Steiner AM, Ghirlando R, Li NS, Rowland SJ, Boocock MR, Stark WM, Piccirilli JA, Rice PA
Complementing ultrafast shape recognition with an optical isomerism descriptor.
1. J Mol Graph Model - published November 1, 2010
2. Zhou T, Lafleur K, Caflisch A
How immune peptidases change specificity: cathepsin G gained tryptic function but lost efficiency during primate evolution.
1. J Immunol - published November 1, 2010
2. Raymond WW, Trivedi NN, Makarova A, Ray M, Craik CS, Caughey GH
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1.
1. Nat Med - published November 1, 2010
2. Herker E, Harris C, Hernandez C, Carpentier A, Kaehlcke K, Rosenberg AR, Farese RV Jr, Ott M
Visualizing the transfer-messenger RNA as the ribosome resumes translation.
1. EMBO J - published November 1, 2010
2. Fu J, Hashem Y, Wower I, Lei J, Liao HY, Zwieb C, Wower J, Frank J
Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.
1. Development - published November 1, 2010
2. Yu H, Smallwood PM, Wang Y, Vidaltamayo R, Reed R, Nathans J
The binding of β-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors.
1. Bioorg Med Chem - published November 1, 2010
2. Alexacou KM, Tenchiu Deleanu AC, Chrysina ED, Charavgi MD, Kostas ID, Zographos SE, Oikonomakos NG, Leonidas DD
NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
1. Nat Struct Mol Biol - published November 1, 2010
2. Güttler T, Madl T, Neumann P, Deichsel D, Corsini L, Monecke T, Ficner R, Sattler M, Görlich D
Synthesis of peptide macrocycles using unprotected amino aldehydes.
1. Nat Protoc - published November 1, 2010
2. Rotstein BH, Rai V, Hili R, Yudin AK
Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel.
1. Nat Struct Mol Biol - published November 1, 2010
2. Hilf RJ, Bertozzi C, Zimmermann I, Reiter A, Trauner D, Dutzler R
Purification, crystallization and preliminary X-ray diffraction analysis of the carbohydrate-binding region of the Streptococcus gordonii adhesin GspB.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published November 1, 2010
2. Pyburn TM, Yankovskaya V, Bensing BA, Cecchini G, Sullam PM, Iverson TM
When cytoskeletal worlds collide.
1. Proc Natl Acad Sci U S A - published November 1, 2010
2. Nogales E
Structure of a SLC26 anion transporter STAS domain in complex with acyl carrier protein: implications for E. coli YchM in fatty acid metabolism.
1. Structure - published November 1, 2010
2. Babu M, Greenblatt JF, Emili A, Strynadka NC, Reithmeier RA, Moraes TF
Characterization of engineered actin binding proteins that control filament assembly and structure.
1. PLoS One - published November 1, 2010
2. Brawley CM, Uysal S, Kossiakoff AA, Rock RS
FBG1 is a promiscuous ubiquitin ligase that sequesters APC2 and causes S-phase arrest.
1. Cell Cycle - published November 1, 2010
2. Wen H, Kim N, Fuentes EJ, Mallinger A, Gonzalez-Alegre P, Glenn KA
The Nitric Oxide Prodrug V-PROLI/NO Inhibits Cellular Uptake of Proline.
1. ACS Med Chem Lett - published November 1, 2010
2. Hong SY, Borchert GL, Maciag AE, Nandurdikar RS, Saavedra JE, Keefer LK, Phang JM, Chakrapani H
RhoGDI3 and RhoG: Vesicular trafficking and interactions with the Sec3 Exocyst subunit.
1. Small GTPases - published November 1, 2010
2. Morin A, Cordelières FP, Cherfils J, Olofsson B
Molecular Basis for Drug Resistance in HIV-1 Protease.
1. Viruses - published November 1, 2010
2. Ali A, Bandaranayake RM, Cai Y, King NM, Kolli M, Mittal S, Murzycki JF, Nalam MN, Nalivaika EA, Ozen A, Prabu-Jeyabalan MM, Thayer K, Schiffer CA