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55 Member Publications for September 2010

In vitro bypass of the major malondialdehyde- and base propenal-derived DNA adduct by human Y-family DNA polymerases κ, ι, and Rev1.
1. Biochemistry - published September 28, 2010
Bacterial TEM: new insights from cryo-microscopy.
1. Methods Cell Biol - published September 28, 2010
2. Pilhofer M, Ladinsky MS, McDowall AW, Jensen GJ
Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.
1. J Med Chem - published September 23, 2010
Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
1. Science - published September 17, 2010
Therapeutic targeting of C-terminal binding protein in human cancer.
1. Cell Cycle - published September 15, 2010
Structural basis of low-affinity nickel binding to the nickel-responsive transcription factor NikR from Escherichia coli.
1. Biochemistry - published September 14, 2010
Searching for the Nik operon: how a ligand-responsive transcription factor hunts for its DNA binding site.
1. Biochemistry - published September 14, 2010
Complete structural model of Escherichia coli RNA polymerase from a hybrid approach.
1. PLoS Biol - published September 14, 2010
Modeling the hydration layer around proteins: HyPred.
1. Biophys J - published September 8, 2010
2. Virtanen JJ, Makowski L, Sosnick TR, Freed KF
PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler.
1. Structure - published September 8, 2010
2. Cuesta-Seijo JA, Neale C, Khan MA, Moktar J, Tran CD, Bishop RE, Pomès R, Privé GG
Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism.
1. Structure - published September 8, 2010
2. ter Haar E, Koth CM, Abdul-Manan N, Swenson L, Coll JT, Lippke JA, Lepre CA, Garcia-Guzman M, Moore JM
Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators.
1. Structure - published September 8, 2010
2. Marsh JA, Dancheck B, Ragusa MJ, Allaire M, Forman-Kay JD, Peti W
Structure of the PTEN-like region of auxilin, a detector of clathrin-coated vesicle budding.
1. Structure - published September 8, 2010
Structure-function relationships of the alpha/beta-hydrolase fold domain of neuroligin: a comparison with acetylcholinesterase.
1. Chem Biol Interact - published September 6, 2010
2. Leone P, Comoletti D, Taylor P, Bourne Y, Marchot P
A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes.
1. J Biol Chem - published September 3, 2010
2. Zhou QL, Jiang ZY, Mabardy AS, Del Campo CM, Lambright DG, Holik J, Fogarty KE, Straubhaar J, Nicoloro S, Chawla A, Czech MP
The NusA N-terminal domain is necessary and sufficient for enhancement of transcriptional pausing via interaction with the RNA exit channel of RNA polymerase.
1. J Mol Biol - published September 3, 2010
2. Ha KS, Toulokhonov I, Vassylyev DG, Landick R
RNA secondary structure prediction by using discrete mathematics: an interdisciplinary research experience for undergraduate students.
1. CBE Life Sci Educ - published September 3, 2010
2. Ellington R, Wachira J, Nkwanta A
Crystal structure of the Formin mDia1 in autoinhibited conformation.
1. PLoS One - published September 3, 2010
2. Otomo T, Tomchick DR, Otomo C, Machius M, Rosen MK
Crystal structure of a complex between amino and carboxy terminal fragments of mDia1: insights into autoinhibition of diaphanous-related formins.
1. PLoS One - published September 3, 2010
2. Nezami A, Poy F, Toms A, Zheng W, Eck MJ
The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin-dependent endocytosis.
1. PLoS Pathog - published September 3, 2010
2. Cureton DK, Massol RH, Whelan SP, Kirchhausen T
Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4.
1. J Biol Chem - published September 2, 2010
2. Shukla AK, Kim J, Ahn S, Xiao K, Shenoy SK, Liedtke W, Lefkowitz RJ
Modulating heme redox potential through protein-induced porphyrin distortion.
1. J Am Chem Soc - published September 2, 2010
2. Olea C Jr, Kuriyan J, Marletta MA
Biophysical analysis of HTLV-1 particles reveals novel insights into particle morphology and Gag stochiometry.
1. Retrovirology - published September 2, 2010
2. Grigsby IF, Zhang W, Johnson JL, Fogarty KH, Chen Y, Rawson JM, Crosby AJ, Mueller JD, Mansky LM
The stepping pattern of myosin X is adapted for processive motility on bundled actin.
1. Biophys J - published September 2, 2010
2. Ricca BL, Rock RS
Acetylation of tau inhibits its degradation and contributes to tauopathy.
1. Neuron - published September 2, 2010
2. Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L
Co-expression of ferrochelatase allows for complete heme incorporation into recombinant proteins produced in E. coli.
1. Protein Expr Purif - published September 1, 2010
2. Sudhamsu J, Kabir M, Airola MV, Patel BA, Yeh SR, Rousseau DL, Crane BR
Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes.
1. Mol Cell Proteomics - published September 1, 2010
2. Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK
Pushing the limits of what is achievable in protein-DNA docking: benchmarking HADDOCK's performance.
1. Nucleic Acids Res - published September 1, 2010
2. van Dijk M, Bonvin AM
Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells.
1. J Virol Methods - published September 1, 2010
2. Finzi A, Pacheco B, Zeng X, Kwon YD, Kwong PD, Sodroski J
Designed ankyrin repeat proteins: a novel tool for testing epidermal growth factor receptor 2 expression in breast cancer.
1. Mod Pathol - published September 1, 2010
2. Theurillat JP, Dreier B, Nagy-Davidescu G, Seifert B, Behnke S, Zürrer-Härdi U, Ingold F, Plückthun A, Moch H
Comparison of FcRn- and pIgR-mediated transport in MDCK cells by fluorescence confocal microscopy.
1. Traffic - published September 1, 2010
2. Jerdeva GV, Tesar DB, Huey-Tubman KE, Ladinsky MS, Fraser SE, Bjorkman PJ
An adaptive Expectation-Maximization algorithm with GPU implementation for electron cryomicroscopy.
1. J Struct Biol - published September 1, 2010
2. Tagare HD, Barthel A, Sigworth FJ
Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms.
1. J Biol Chem - published September 1, 2010
2. Boivin S, Cusack S, Ruigrok RW, Hart DJ
Mutational and metal binding analysis of the endonuclease domain of the influenza virus polymerase PA subunit.
1. J Virol - published September 1, 2010
2. Crépin T, Dias A, Palencia A, Swale C, Cusack S, Ruigrok RW
A short N-terminal peptide motif on flavivirus nonstructural protein NS1 modulates cellular targeting and immune recognition.
1. J Virol - published September 1, 2010
2. Youn S, Cho H, Fremont DH, Diamond MS
Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.
1. J Virol - published September 1, 2010
2. Sukupolvi-Petty S, Austin SK, Engle M, Brien JD, Dowd KA, Williams KL, Johnson S, Rico-Hesse R, Harris E, Pierson TC, Fremont DH, Diamond MS
Structural basis for homodimerization of the Src-associated during mitosis, 68-kDa protein (Sam68) Qua1 domain.
1. J Biol Chem - published September 1, 2010
2. Meyer NH, Tripsianes K, Vincendeau M, Madl T, Kateb F, Brack-Werner R, Sattler M
Dissecting BAR domain function in the yeast Amphiphysins Rvs161 and Rvs167 during endocytosis.
1. Mol Biol Cell - published September 1, 2010
2. Youn JY, Friesen H, Kishimoto T, Henne WM, Kurat CF, Ye W, Ceccarelli DF, Sicheri F, Kohlwein SD, McMahon HT, Andrews BJ
Orientation of small multidrug resistance transporter subunits in the membrane: correlation with the positive-inside rule.
1. J Mol Biol - published September 1, 2010
2. Kolbusz MA, ter Horst R, Slotboom DJ, Lolkema JS
Residue-resolved stability of full-consensus ankyrin repeat proteins probed by NMR.
1. J Mol Biol - published September 1, 2010
2. Wetzel SK, Ewald C, Settanni G, Jurt S, Plückthun A, Zerbe O
The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease.
1. Trends Mol Med - published September 1, 2010
2. Ye X, Wang Y, Nathans J
Structural and functional studies of WlbA: A dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid .
1. Biochemistry - published September 1, 2010
2. Thoden JB, Holden HM
Fast live simultaneous multiwavelength four-dimensional optical microscopy.
1. Proc Natl Acad Sci U S A - published September 1, 2010
2. Carlton PM, Boulanger J, Kervrann C, Sibarita JB, Salamero J, Gordon-Messer S, Bressan D, Haber JE, Haase S, Shao L, Winoto L, Matsuda A, Kner P, Uzawa S, Gustafsson M, Kam Z, Agard DA, Sedat JW
A split active site couples cap recognition by Dcp2 to activation.
1. Nat Struct Mol Biol - published September 1, 2010
2. Floor SN, Jones BN, Hernandez GA, Gross JD
MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments.
1. J Synchrotron Radiat - published September 1, 2010
2. Gabadinho J, Beteva A, Guijarro M, Rey-Bakaikoa V, Spruce D, Bowler MW, Brockhauser S, Flot D, Gordon EJ, Hall DR, Lavault B, McCarthy AA, McCarthy J, Mitchell E, Monaco S, Mueller-Dieckmann C, Nurizzo D, Ravelli RB, Thibault X, Walsh MA, Leonard GA, McSweeney SM
Structural basis for selective activation of ABA receptors.
1. Nat Struct Mol Biol - published September 1, 2010
2. Peterson FC, Burgie ES, Park SY, Jensen DR, Weiner JJ, Bingman CA, Chang CE, Cutler SR, Phillips GN Jr, Volkman BF
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering.
1. Proc Natl Acad Sci U S A - published September 1, 2010
2. Li H, Korennykh AV, Behrman SL, Walter P
Classic and contemporary approaches to modeling biochemical reactions.
1. Genes Dev - published September 1, 2010
2. Chen WW, Niepel M, Sorger PK
A smooth and differentiable bulk-solvent model for macromolecular diffraction.
1. Acta Crystallogr D Biol Crystallogr - published September 1, 2010
2. Fenn TD, Schnieders MJ, Brunger AT
High-speed crystal detection and characterization using a fast-readout detector.
1. Acta Crystallogr D Biol Crystallogr - published September 1, 2010
2. Aishima J, Owen RL, Axford D, Shepherd E, Winter G, Levik K, Gibbons P, Ashton A, Evans G
Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published September 1, 2010
2. Irimia A, Loukachevitch LV, Eoff RL, Guengerich FP, Egli M
Targeting mitochondrial glutaminase activity inhibits oncogenic transformation.
1. Cancer Cell - published September 1, 2010
2. Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio AL, Dias SM, Dang CV, Cerione RA
Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription.
1. PLoS Pathog - published September 1, 2010
2. Reguera J, Weber F, Cusack S
Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid.
1. Plant Cell - published September 1, 2010
2. Messing SA, Gabelli SB, Echeverria I, Vogel JT, Guan JC, Tan BC, Klee HJ, McCarty DR, Amzel LM
PI3Kα inhibitors that inhibit metastasis.
1. Oncotarget - published September 1, 2010
2. Schmidt-Kittler O, Zhu J, Yang J, Liu G, Hendricks W, Lengauer C, Gabelli SB, Kinzler KW, Vogelstein B, Huso DL, Zhou S