Member Publications

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54 Member Publications for August 2010

Structure of the Sec13-Sec16 edge element, a template for assembly of the COPII vesicle coat.
1. J Cell Biol - published August 9, 2010
2. Whittle JR, Schwartz TU
Structural and enzymatic insights into the ATP binding and autophosphorylation mechanism of a sensor histidine kinase.
1. J Biol Chem - published August 6, 2010
2. Trajtenberg F, Graña M, Ruétalo N, Botti H, Buschiazzo A
Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein.
1. Cell - published August 6, 2010
2. Subramanian R, Wilson-Kubalek EM, Arthur CP, Bick MJ, Campbell EA, Darst SA, Milligan RA, Kapoor TM
Experimental evolution of adenylate kinase reveals contrasting strategies toward protein thermostability.
1. Biophys J - published August 4, 2010
2. Miller C, Davlieva M, Wilson C, White KI, Couñago R, Wu G, Myers JC, Wittung-Stafshede P, Shamoo Y
Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase.
1. Proc Natl Acad Sci U S A - published August 3, 2010
2. Vaithiyalingam S, Warren EM, Eichman BF, Chazin WJ
Antagonistic anti-urokinase plasminogen activator receptor (uPAR) antibodies significantly inhibit uPAR-mediated cellular signaling and migration.
1. J Biol Chem - published August 2, 2010
2. Duriseti S, Goetz DH, Hostetter DR, LeBeau AM, Wei Y, Craik CS
Unconventional processive mechanics of non-muscle myosin IIB.
1. J Biol Chem - published August 2, 2010
2. Norstrom MF, Smithback PA, Rock RS
Structured post-IQ domain governs selectivity of myosin X for fascin-actin bundles.
1. J Biol Chem - published August 2, 2010
2. Nagy S, Rock RS
Actin cross-link assembly and disassembly mechanics for alpha-Actinin and fascin.
1. J Biol Chem - published August 2, 2010
2. Courson DS, Rock RS
The yeast mitochondrial citrate transport protein: molecular determinants of its substrate specificity.
1. J Biol Chem - published August 2, 2010
2. Aluvila S, Kotaria R, Sun J, Mayor JA, Walters DE, Harrison DHT, Kaplan RS
Structural insights into the catalytic mechanism of bacterial guanosine-diphospho-D-mannose pyrophosphorylase and its regulation by divalent ions.
1. J Biol Chem - published August 2, 2010
2. Pelissier MC, Lesley SA, Kuhn P, Bourne Y
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.
1. Angew Chem Int Ed Engl - published August 2, 2010
2. Scaglione JB, Akey DL, Sullivan R, Kittendorf JD, Rath CM, Kim ES, Smith JL, Sherman DH
Lysophospholipid micelles sustain the stability and catalytic activity of diacylglycerol kinase in the absence of lipids.
1. Biochemistry - published August 2, 2010
2. Koehler J, Sulistijo ES, Sakakura M, Kim HJ, Ellis CD, Sanders CR
Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).
1. Proc Natl Acad Sci U S A - published August 2, 2010
2. Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, Mizuno K, Ma'ayan A, Gygi SP, Lefkowitz RJ
Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners.
1. Proc Natl Acad Sci U S A - published August 2, 2010
2. Schulman S, Wang B, Li W, Rapoport TA
Structure and function of the polymerase core of TRAMP, a RNA surveillance complex.
1. Proc Natl Acad Sci U S A - published August 2, 2010
2. Hamill S, Wolin SL, Reinisch KM
Up a hydrophobic creek with a short paddle.
1. Cell - published August 2, 2010
2. Hulse RE, Li Q, Perozo E
The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments.
1. Cell - published August 2, 2010
2. Corbett KD, Yip CK, Ee LS, Walz T, Amon A, Harrison SC
Virology. Looking inside adenovirus.
1. Science - published August 2, 2010
2. Harrison SC
Building macromolecular assemblies by information-driven docking: introducing the HADDOCK multibody docking server.
1. Mol Cell Proteomics - published August 1, 2010
2. Karaca E, Melquiond AS, de Vries SJ, Kastritis PL, Bonvin AM
Direct binding of cholesterol to the amyloid precursor protein: An important interaction in lipid-Alzheimer's disease relationships?
1. Biochim Biophys Acta - published August 1, 2010
2. Beel AJ, Sakakura M, Barrett PJ, Sanders CR
Histone chaperones, histone acetylation, and the fluidity of the chromogenome.
1. J Cell Physiol - published August 1, 2010
2. Hansen JC, Nyborg JK, Luger K, Stargell LA
Cloning and identification of tissue-specific expression of KCNN4 splice variants in rat colon.
1. Am J Physiol Cell Physiol - published August 1, 2010
2. Barmeyer C, Rahner C, Yang Y, Sigworth FJ, Binder HJ, Rajendran VM
Design and directed evolution of a dideoxy purine nucleoside phosphorylase.
1. Protein Eng Des Sel - published August 1, 2010
2. Nannemann DP, Kaufmann KW, Meiler J, Bachmann BO
Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi.
1. J Biol Chem - published August 1, 2010
2. Lepesheva GI, Hargrove TY, Anderson S, Kleshchenko Y, Furtak V, Wawrzak Z, Villalta F, Waterman MR
Double-stranded RNA-dependent ATPase DRH-3: insight into its role in RNAsilencing in Caenorhabditis elegans.
1. J Biol Chem - published August 1, 2010
2. Matranga C, Pyle AM
Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
1. J Virol - published August 1, 2010
2. Pancera M, McLellan JS, Wu X, Zhu J, Changela A, Schmidt SD, Yang Y, Zhou T, Phogat S, Mascola JR, Kwong PD
Rationally improving LOV domain-based photoswitches.
1. Nat Methods - published August 1, 2010
2. Strickland D, Yao X, Gawlak G, Rosen MK, Gardner KH, Sosnick TR
The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer.
1. Nat Chem Biol - published August 1, 2010
2. Stewart ML, Fire E, Keating AE, Walensky LD
A transient kinetic approach to investigate nucleoside inhibitors of mitochondrial DNA polymerase gamma.
1. Methods - published August 1, 2010
2. Anderson KS
Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).
1. Chem Res Toxicol - published August 1, 2010
2. Christov PP, Petrova KV, Shanmugam G, Kozekov ID, Kozekova A, Guengerich FP, Stone MP, Rizzo CJ
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1.
1. Science - published August 1, 2010
2. Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, O'Dell S, Louder MK, Wycuff DL, Feng Y, Nason M, Doria-Rose N, Connors M, Kwong PD, Roederer M, Wyatt RT, Nabel GJ, Mascola JR
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
1. Science - published August 1, 2010
2. Zhou T, Georgiev I, Wu X, Yang ZY, Dai K, Finzi A, Kwon YD, Scheid JF, Shi W, Xu L, Yang Y, Zhu J, Nussenzweig MC, Sodroski J, Shapiro L, Nabel GJ, Mascola JR, Kwong PD
Microtubule nucleating gamma-TuSC assembles structures with 13-fold microtubule-like symmetry.
1. Nature - published August 1, 2010
2. Kollman JM, Polka JK, Zelter A, Davis TN, Agard DA
Argonaute MID domain takes centre stage.
1. EMBO Rep - published August 1, 2010
2. Faehnle CR, Joshua-Tor L
From the Cover: Charge interactions can dominate the dimensions of intrinsically disordered proteins.
1. Proc Natl Acad Sci U S A - published August 1, 2010
2. Müller-Späth S, Soranno A, Hirschfeld V, Hofmann H, Rüegger S, Reymond L, Nettels D, Schuler B
Transcriptional profiles of drought-responsive genes in modulating transcription signal transduction, and biochemical pathways in tomato.
1. J Exp Bot - published August 1, 2010
2. Gong P, Zhang J, Li H, Yang C, Zhang C, Zhang X, Khurram Z, Zhang Y, Wang T, Fei Z, Ye Z
Exercise-induced left ventricular systolic dysfunction in women heterozygous for dystrophinopathy.
1. J Am Soc Echocardiogr - published August 1, 2010
2. Weiss RM, Kerber RE, Jones JK, Stephan CM, Trout CJ, Lindower PD, Staffey KS, Campbell KP, Mathews KD
Structure of a C-terminal fragment of its Vps53 subunit suggests similarity of Golgi-associated retrograde protein (GARP) complex to a family of tethering complexes.
1. Proc Natl Acad Sci U S A - published August 1, 2010
2. Vasan N, Hutagalung A, Novick P, Reinisch KM
Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic.
1. Proc Natl Acad Sci U S A - published August 1, 2010
2. Bird GH, Madani N, Perry AF, Princiotto AM, Supko JG, He X, Gavathiotis E, Sodroski JG, Walensky LD
Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis.
1. Proc Natl Acad Sci U S A - published August 1, 2010
2. Khare D, Wang B, Gu L, Razelun J, Sherman DH, Gerwick WH, Håkansson K, Smith JL
Chemoselective peptidomimetic ligation using thioacid peptides and aziridine templates.
1. J Am Chem Soc - published August 1, 2010
2. Assem N, Natarajan A, Yudin AK
Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.
1. Proc Natl Acad Sci U S A - published August 1, 2010
2. Chen X, Xie C, Nishida N, Li Z, Walz T, Springer TA
The force be with you: a mechanoreceptor channel in proprioception and touch.
1. Neuron - published August 1, 2010
2. Wilson RI, Corey DP
Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase.
1. Structure - published August 1, 2010
2. Zheng J, Taylor CA, Piasecki SK, Keatinge-Clay AT
Structure of the LexA-DNA complex and implications for SOS box measurement.
1. Nature - published August 1, 2010
2. Zhang AP, Pigli YZ, Rice PA
The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation.
1. Mol Cell - published August 1, 2010
2. Gerace EL, Halic M, Moazed D
The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing.
1. Mol Cell - published August 1, 2010
2. Koodathingal P, Novak T, Piccirilli JA, Staley JP
CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule.
1. Dev Cell - published August 1, 2010
2. Al-Bassam J, Kim H, Brouhard G, van Oijen A, Harrison SC, Chang F
A mechanically stabilized receptor-ligand flex-bond important in the vasculature.
1. Nature - published August 1, 2010
2. Kim J, Zhang CZ, Zhang X, Springer TA
Structure and function of eukaryotic fatty acid synthases.
1. Q Rev Biophys - published August 1, 2010
2. Maier T, Leibundgut M, Boehringer D, Ban N
Unlocking the eukaryotic membrane protein structural proteome.
1. Curr Opin Struct Biol - published August 1, 2010
2. Lee JK, Stroud RM
Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection.
1. PLoS Pathog - published August 1, 2010
2. Hannan TJ, Mysorekar IU, Hung CS, Isaacson-Schmid ML, Hultgren SJ
VASP: a volumetric analysis of surface properties yields insights into protein-ligand binding specificity.
1. PLoS Comput Biol - published August 1, 2010
2. Chen BY, Honig B