Member Publications

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59 Member Publications for March 2010

Origins of specificity in protein-DNA recognition.
1. Annu Rev Biochem - published March 26, 2010
2. Rohs R, Jin X, West SM, Joshi R, Honig B, Mann RS
Structure and dynamics of a processive Brownian motor: the translating ribosome.
1. Annu Rev Biochem - published March 19, 2010
2. Frank J, Gonzalez RL Jr
The adenovirus type 3 dodecahedron's RGD loop comprises an HSPG binding site that influences integrin binding.
1. J Biomed Biotechnol - published March 13, 2010
2. Gout E, Schoehn G, Fenel D, Lortat-Jacob H, Fender P
An efficient protocol for NMR-spectroscopy-based structure determination of protein complexes in solution.
1. Angew Chem Int Ed Engl - published March 8, 2010
2. Simon B, Madl T, Mackereth CD, Nilges M, Sattler M
Cell-free protein synthesis technology in NMR high-throughput structure determination.
1. Methods Mol Biol - published March 6, 2010
2. Makino S, Goren MA, Fox BG, Markley JL
Molecular and structural insight into proNGF engagement of p75NTR and sortilin.
1. J Mol Biol - published March 5, 2010
2. Feng D, Kim T, Ozkan E, Light M, Torkin R, Teng KK, Hempstead BL, Garcia KC
The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1.
1. EMBO J - published March 3, 2010
2. Smith MJ, Hardy WR, Li GY, Goudreault M, Hersch S, Metalnikov P, Starostine A, Pawson T, Ikura M
POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation.
1. EMBO J - published March 3, 2010
2. Latrick CM, Cech TR
Development of an activity assay for discovery of inhibitors of lipopolysaccharide transport.
1. J Am Chem Soc - published March 3, 2010
2. Gronenberg LS, Kahne D
Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion.
1. Biochemistry - published March 3, 2010
2. Shanmugam G, Kozekov ID, Guengerich FP, Rizzo CJ, Stone MP
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism.
1. Proc Natl Acad Sci U S A - published March 3, 2010
2. Bourne Y, Radic Z, Aráoz R, Talley TT, Benoit E, Servent D, Taylor P, Molgó J, Marchot P
Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex.
1. J Biol Chem - published March 2, 2010
2. Kobayashi M, Ab E, Bonvin AMJJ, Siegal G
Alpha4 is a ubiquitin-binding protein that regulates protein serine/threonine phosphatase 2A ubiquitination.
1. Biochemistry - published March 2, 2010
2. McConnell JL, Watkins GR, Soss SE, Franz HS, McCorvey LR, Spiller BW, Chazin WJ, Wadzinski BE
Crystal structure of Get4-Get5 complex and its interactions with Sgt2, Get3, and Ydj1.
1. J Biol Chem - published March 2, 2010
2. Chang YW, Chuang YC, Ho YC, Cheng MY, Sun YJ, Hsiao CD, Wang C
Tight hydrophobic contacts with the SecB chaperone prevent folding of substrate proteins.
1. Biochemistry - published March 2, 2010
2. Bechtluft P, Kedrov A, Slotboom DJ, Nouwen N, Tans SJ, Driessen AJ
Structure of sterol aliphatic chains affects yeast cell shape and cell fusion during mating.
1. Proc Natl Acad Sci U S A - published March 2, 2010
2. Aguilar PS, Heiman MG, Walther TC, Engel A, Schwudke D, Gushwa N, Kurzchalia T, Walter P
Allosteric protein kinase regulation by pseudokinases: insights from STRAD.
1. Sci Signal - published March 2, 2010
2. Rajakulendran T, Sicheri F
Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane.
1. Proc Natl Acad Sci U S A - published March 2, 2010
2. Chng SS, Ruiz N, Chimalakonda G, Silhavy TJ, Kahne D
The activated state of a sodium channel voltage sensor in a membrane environment.
1. Proc Natl Acad Sci U S A - published March 2, 2010
2. Chakrapani S, Sompornpisut P, Intharathep P, Roux B, Perozo E
The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions.
1. Mol Cell - published March 2, 2010
2. Andrews AJ, Chen X, Zevin A, Stargell LA, Luger K
Experience-dependent gene expression in adult visual cortex.
1. Cereb Cortex - published March 1, 2010
2. Chen J, Yamahachi H, Gilbert CD
Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
1. Proteins - published March 1, 2010
2. Huang CH, Gabelli SB, Oldfield E, Amzel LM
Proteomics of Saccharomyces cerevisiae Organelles.
1. Mol Cell Proteomics - published March 1, 2010
2. Wiederhold E, Veenhoff LM, Poolman B, Slotboom DJ
Somatic mutations in PI3Kalpha: structural basis for enzyme activation and drug design.
1. Biochim Biophys Acta - published March 1, 2010
2. Gabelli SB, Mandelker D, Schmidt-Kittler O, Vogelstein B, Amzel LM
Structural and mechanistic underpinnings of the differential drug sensitivity of EGFR mutations in non-small cell lung cancer.
1. Biochim Biophys Acta - published March 1, 2010
2. Eck MJ, Yun CH
Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region.
1. J Virol - published March 1, 2010
2. Ofek G, McKee K, Yang Y, Yang ZY, Skinner J, Guenaga FJ, Wyatt R, Zwick MB, Nabel GJ, Mascola JR, Kwong PD
Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses.
1. J Virol - published March 1, 2010
2. Krause JC, Tumpey TM, Huffman CJ, McGraw PA, Pearce MB, Tsibane T, Hai R, Basler CF, Crowe JE Jr
Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases.
1. Protein Sci - published March 1, 2010
2. Marcotte DJ, Liu YT, Arduini RM, Hession CA, Miatkowski K, Wildes CP, Cullen PF, Hong V, Hopkins BT, Mertsching E, Jenkins TJ, Romanowski MJ, Baker DP, Silvian LF
Comparison of human solute carriers.
1. Protein Sci - published March 1, 2010
2. Schlessinger A, Matsson P, Shima JE, Pieper U, Yee SW, Kelly L, Apeltsin L, Stroud RM, Ferrin TE, Giacomini KM, Sali A
Conserved tertiary couplings stabilize elements in the PDZ fold, leading to characteristic patterns of domain conformational flexibility.
1. Protein Sci - published March 1, 2010
2. Ho BK, Agard DA
Biochemical and structural characterization of cathepsin L-processed Ebola virus glycoprotein: implications for viral entry and immunogenicity.
1. J Virol - published March 1, 2010
2. Hood CL, Abraham J, Boyington JC, Leung K, Kwong PD, Nabel GJ
Protein structure prediction enhanced with evolutionary diversity: SPEED.
1. Protein Sci - published March 1, 2010
2. DeBartolo J, Hocky G, Wilde M, Xu J, Freed KF, Sosnick TR
The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.
1. Blood - published March 1, 2010
2. Xu GW, Ali M, Wood TE, Wong D, Maclean N, Wang X, Gronda M, Skrtic M, Li X, Hurren R, Mao X, Venkatesan M, Beheshti Zavareh R, Ketela T, Reed JC, Rose D, Moffat J, Batey RA, Dhe-Paganon S, Schimmer AD
Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis.
1. Infect Immun - published March 1, 2010
2. Anderson GG, Goller CC, Justice S, Hultgren SJ, Seed PC
The 2'-OH group at the group II intron terminus acts as a proton shuttle.
1. Nat Chem Biol - published March 1, 2010
2. Roitzsch M, Fedorova O, Pyle AM
Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus.
1. Bioorg Med Chem Lett - published March 1, 2010
2. Lee K, Campbell J, Swoboda JG, Cuny GD, Walker S
Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
1. Nat Struct Mol Biol - published March 1, 2010
2. Chao LH, Pellicena P, Deindl S, Barclay LA, Schulman H, Kuriyan J
A molecular mechanism for proton-dependent gating in KcsA.
1. FEBS Lett - published March 1, 2010
2. Cuello LG, Cortes DM, Jogini V, Sompornpisut A, Perozo E
3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta.
1. Bioorg Med Chem Lett - published March 1, 2010
2. Arnost M, Pierce A, ter Haar E, Lauffer D, Madden J, Tanner K, Green J
Assessing the stability of membrane proteins to detect ligand binding using differential static light scattering.
1. J Biomol Screen - published March 1, 2010
2. Senisterra GA, Ghanei H, Khutoreskaya G, Dobrovetsky E, Edwards AM, Privé GG, Vedadi M
Design and characterization of a constitutively open KcsA.
1. FEBS Lett - published March 1, 2010
2. Cuello LG, Jogini V, Cortes DM, Sompornpisut A, Purdy MD, Wiener MC, Perozo E
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.
1. Nat Struct Mol Biol - published March 1, 2010
2. Rechkoblit O, Kolbanovskiy A, Malinina L, Geacintov NE, Broyde S, Patel DJ
Macrocyclization of linear peptides enabled by amphoteric molecules.
1. J Am Chem Soc - published March 1, 2010
2. Hili R, Rai V, Yudin AK
A distinct mechanism for the ABC transporter BtuCD-BtuF revealed by the dynamics of complex formation.
1. Nat Struct Mol Biol - published March 1, 2010
2. Lewinson O, Lee AT, Locher KP, Rees DC
When ribosomes go bad: diseases of ribosome biogenesis.
1. Mol Biosyst - published March 1, 2010
2. Freed EF, Bleichert F, Dutca LM, Baserga SJ
Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.
1. Nat Struct Mol Biol - published March 1, 2010
2. Vrljic M, Strop P, Ernst JA, Sutton RB, Chu S, Brunger AT
Two-step adhesive binding by classical cadherins.
1. Nat Struct Mol Biol - published March 1, 2010
2. Harrison OJ, Bahna F, Katsamba PS, Jin X, Brasch J, Vendome J, Ahlsen G, Carroll KJ, Price SR, Honig B, Shapiro L
T-cadherin structures reveal a novel adhesive binding mechanism.
1. Nat Struct Mol Biol - published March 1, 2010
2. Ciatto C, Bahna F, Zampieri N, VanSteenhouse HC, Katsamba PS, Ahlsen G, Harrison OJ, Brasch J, Jin X, Posy S, Vendome J, Ranscht B, Jessell TM, Honig B, Shapiro L
Engineering cis-telomerase RNAs that add telomeric repeats to themselves.
1. Proc Natl Acad Sci U S A - published March 1, 2010
2. Qiao F, Goodrich KJ, Cech TR
Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2.
1. Structure - published March 1, 2010
2. Lupardus PJ, Birnbaum ME, Garcia KC
The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.
1. Cell Host Microbe - published March 1, 2010
2. Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M
The eNMR platform for structural biology.
1. J Struct Funct Genomics - published March 1, 2010
2. Bonvin AM, Rosato A, Wassenaar TA
Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions.
1. Mol Cell - published March 1, 2010
2. Finzi A, Xiang SH, Pacheco B, Wang L, Haight J, Kassa A, Danek B, Pancera M, Kwong PD, Sodroski J
Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.
1. Cell Host Microbe - published March 1, 2010
2. Ohol YM, Goetz DH, Chan K, Shiloh MU, Craik CS, Cox JS
Functional interaction between telomere protein TPP1 and telomerase.
1. Genes Dev - published March 1, 2010
2. Zaug AJ, Podell ER, Nandakumar J, Cech TR
High-throughput computational structure-based characterization of protein families: START domains and implications for structural genomics.
1. J Struct Funct Genomics - published March 1, 2010
2. Lee H, Li Z, Silkov A, Fischer M, Petrey D, Honig B, Murray D
Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase.
1. Structure - published March 1, 2010
2. Mittag T, Marsh J, Grishaev A, Orlicky S, Lin H, Sicheri F, Tyers M, Forman-Kay JD
Structure of concatenated HAMP domains provides a mechanism for signal transduction.
1. Structure - published March 1, 2010
2. Airola MV, Watts KJ, Bilwes AM, Crane BR
Flu channel drug resistance: a tale of two sites.
1. Protein Cell - published March 1, 2010
2. Pielak RM, Chou JJ