Member Publications

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52 Member Publications for January 2010

Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.
1. Science - published January 8, 2010
2. Liu X, Bushnell DA, Wang D, Calero G, Kornberg RD
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
1. Nature - published January 7, 2010
2. Bokoch MP, Zou Y, Rasmussen SG, Liu CW, Nygaard R, Rosenbaum DM, Fung JJ, Choi HJ, Thian FS, Kobilka TS, Puglisi JD, Weis WI, Pardo L, Prosser RS, Mueller L, Kobilka BK
NMR evidence for differential phosphorylation-dependent interactions in WT and DeltaF508 CFTR.
1. EMBO J - published January 6, 2010
2. Kanelis V, Hudson RP, Thibodeau PH, Thomas PJ, Forman-Kay JD
Optimal hematocrit for maximal exercise performance in acute and chronic erythropoietin-treated mice.
1. Proc Natl Acad Sci U S A - published January 5, 2010
2. Schuler B, Arras M, Keller S, Rettich A, Lundby C, Vogel J, Gassmann M
Wall teichoic acid function, biosynthesis, and inhibition.
1. Chembiochem - published January 4, 2010
2. Swoboda JG, Campbell J, Meredith TC, Walker S
Analysis of the role of PCNA-DNA contacts during clamp loading.
1. BMC Struct Biol - published January 3, 2010
2. McNally R, Bowman GD, Goedken ER, O'Donnell M, Kuriyan J
Molecular evolution of multisubunit RNA polymerases: sequence analysis.
1. J Mol Biol - published January 2, 2010
2. Lane WJ, Darst SA
Molecular evolution of multisubunit RNA polymerases: structural analysis.
1. J Mol Biol - published January 2, 2010
2. Lane WJ, Darst SA
The length of the bound fatty acid influences the dynamics of the acyl carrier protein and the stability of the thioester bond.
1. Biochemistry - published January 2, 2010
2. Zornetzer GA, Tanem J, Fox BG, Markley JL
EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation.
1. Proc Natl Acad Sci U S A - published January 2, 2010
2. Li B, Antonyak MA, Druso JE, Cheng L, Nikitin AY, Cerione RA
Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210.
1. N Engl J Med - published January 2, 2010
2. Smits P, Bolton AD, Funari V, Hong M, Boyden ED, Lu L, Manning DK, Dwyer ND, Moran JL, Prysak M, Merriman B, Nelson SF, Bonafé L, Superti-Furga A, Ikegawa S, Krakow D, Cohn DH, Kirchhausen T, Warman ML, Beier DR
Identification of RACK1 and protein kinase Calpha as integral components of the mammalian circadian clock.
1. Science - published January 2, 2010
2. Robles MS, Boyault C, Knutti D, Padmanabhan K, Weitz CJ
SAMPLEX: automatic mapping of perturbed and unperturbed regions of proteins and complexes.
1. BMC Bioinformatics - published January 2, 2010
2. Krzeminski M, Loth K, Boelens R, Bonvin AM
Acute dynamin inhibition dissects synaptic vesicle recycling pathways that drive spontaneous and evoked neurotransmission.
1. J Neurosci - published January 2, 2010
2. Chung C, Barylko B, Leitz J, Liu X, Kavalali ET
Enhanced efficacy without further cleft closure: reevaluating twist as a source of agonist efficacy in AMPA receptors.
1. J Neurosci - published January 2, 2010
2. Birdsey-Benson A, Gill A, Henderson LP, Madden DR
Structure of a bacterial homologue of vitamin K epoxide reductase.
1. Nature - published January 2, 2010
2. Li W, Schulman S, Dutton RJ, Boyd D, Beckwith J, Rapoport TA
Structural and energetic mechanisms of cooperative autoinhibition and activation of Vav1.
1. Cell - published January 2, 2010
2. Yu B, Martins IR, Li P, Amarasinghe GK, Umetani J, Fernandez-Zapico ME, Billadeau DD, Machius M, Tomchick DR, Rosen MK
The subspace iteration method in protein normal mode analysis.
1. J Comput Chem - published January 1, 2010
2. Sedeh RS, Bathe M, Bathe KJ
Recent advances in segmental isotope labeling of proteins: NMR applications to large proteins and glycoproteins.
1. J Biomol NMR - published January 1, 2010
2. Skrisovska L, Schubert M, Allain FH
Inhibitors of the mitochondrial citrate transport protein: validation of the role of substrate binding residues and discovery of the first purely competitive inhibitor.
1. Mol Pharmacol - published January 1, 2010
2. Aluvila S, Sun J, Harrison DH, Walters DE, Kaplan RS
Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents.
1. J Virol - published January 1, 2010
2. West AP Jr, Galimidi RP, Foglesong CP, Gnanapragasam PN, Klein JS, Bjorkman PJ
Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain.
1. J Biol Chem - published January 1, 2010
2. Phelps CB, Wang RR, Choo SS, Gaudet R
Osmolyte-induced conformational changes in the Hsp90 molecular chaperone.
1. Protein Sci - published January 1, 2010
2. Street TO, Krukenberg KA, Rosgen J, Bolen DW, Agard DA
Structure and function of the PLAA/Ufd3-p97/Cdc48 complex.
1. J Biol Chem - published January 1, 2010
2. Qiu L, Pashkova N, Walker JR, Winistorfer S, Allali-Hassani A, Akutsu M, Piper R, Dhe-Paganon S
Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion site.
1. Nucleic Acids Res - published January 1, 2010
2. Brown KL, Roginskaya M, Zou Y, Altamirano A, Basu AK, Stone MP
Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site.
1. J Biol Chem - published January 1, 2010
2. Hoopes JT, Liu X, Xu X, Demeler B, Folta-Stogniew E, Li C, Ha Y
HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.
1. Traffic - published January 1, 2010
2. Lenassi M, Cagney G, Liao M, Vaupotic T, Bartholomeeusen K, Cheng Y, Krogan NJ, Plemenitas A, Peterlin BM
Protein conformational dynamics of homodimeric hemoglobin revealed by combined time-resolved spectroscopic probes.
1. Chemphyschem - published January 1, 2010
2. Choi J, Muniyappan S, Wallis JT, Royer WE Jr, Ihee H
Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
1. J Biol Chem - published January 1, 2010
2. Lepesheva GI, Park HW, Hargrove TY, Vanhollebeke B, Wawrzak Z, Harp JM, Sundaramoorthy M, Nes WD, Pays E, Chaudhuri M, Villalta F, Waterman MR
Kinase selectivity potential for inhibitors targeting the ATP binding site: a network analysis.
1. Bioinformatics - published January 1, 2010
2. Huang D, Zhou T, Lafleur K, Nevado C, Caflisch A
A structural analysis of the group II intron active site and implications for the spliceosome.
1. RNA - published January 1, 2010
2. Keating KS, Toor N, Perlman PS, Pyle AM
Tertiary architecture of the Oceanobacillus iheyensis group II intron.
1. RNA - published January 1, 2010
2. Toor N, Keating KS, Fedorova O, Rajashankar K, Wang J, Pyle AM
Glycosylated PROLI/NO derivatives as nitric oxide prodrugs.
1. Org Lett - published January 1, 2010
2. Nandurdikar RS, Maciag AE, Hong SY, Chakrapani H, Citro ML, Keefer LK, Saavedra JE
Cytokinesis and the contractile ring in fission yeast: towards a systems-level understanding.
1. Trends Microbiol - published January 1, 2010
2. Bathe M, Chang F
A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
1. Nat Struct Mol Biol - published January 1, 2010
2. Li T, Robert EI, van Breugel PC, Strubin M, Zheng N
Role of the RNA polymerase trigger loop in catalysis and pausing.
1. Nat Struct Mol Biol - published January 1, 2010
2. Zhang J, Palangat M, Landick R
The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases.
1. J Am Chem Soc - published January 1, 2010
2. Perlstein DL, Wang TS, Doud EH, Kahne D, Walker S
Structural and functional characterization of the monomeric U-box domain from E4B.
1. Biochemistry - published January 1, 2010
2. Nordquist KA, Dimitrova YN, Brzovic PS, Ridenour WB, Munro KA, Soss SE, Caprioli RM, Klevit RE, Chazin WJ
Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7.
1. Proc Natl Acad Sci U S A - published January 1, 2010
2. Rajagopal S, Kim J, Ahn S, Craig S, Lam CM, Gerard NP, Gerard C, Lefkowitz RJ
O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding.
1. Science - published January 1, 2010
2. Yoshida-Moriguchi T, Yu L, Stalnaker SH, Davis S, Kunz S, Madson M, Oldstone MB, Schachter H, Wells L, Campbell KP
Walking along the serendipitous path of discovery.
1. Mol Biol Cell - published January 1, 2010
2. Walter P
Heat shock protein 90: inhibitors in clinical trials.
1. J Med Chem - published January 1, 2010
2. Biamonte MA, Van de Water R, Arndt JW, Scannevin RH, Perret D, Lee WC
Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted by Pseudomonas aeruginosa.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published January 1, 2010
2. Bahl CD, MacEachran DP, O'Toole GA, Madden DR
How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
1. Proc Natl Acad Sci U S A - published January 1, 2010
2. Nandakumar J, Podell ER, Cech TR
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
1. Proc Natl Acad Sci U S A - published January 1, 2010
2. Pancera M, Majeed S, Ban YE, Chen L, Huang CC, Kong L, Kwon YD, Stuckey J, Zhou T, Robinson JE, Schief WR, Sodroski J, Wyatt R, Kwong PD
Crystallographic studies of chemically modified nucleic acids: a backward glance.
1. Chem Biodivers - published January 1, 2010
2. Egli M, Pallan PS
Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway.
1. Structure - published January 1, 2010
2. Akey DL, Razelun JR, Tehranisa J, Sherman DH, Gerwick WH, Smith JL
Solution structure of a unique G-quadruplex scaffold adopted by a guanosine-rich human intronic sequence.
1. Structure - published January 1, 2010
2. Kuryavyi V, Patel DJ
Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces.
1. Structure - published January 1, 2010
2. Shandilya SM, Nalam MN, Nalivaika EA, Gross PJ, Valesano JC, Shindo K, Li M, Munson M, Royer WE, Harjes E, Kono T, Matsuo H, Harris RS, Somasundaran M, Schiffer CA
Local protease signaling contributes to neural tube closure in the mouse embryo.
1. Dev Cell - published January 1, 2010
2. Camerer E, Barker A, Duong DN, Ganesan R, Kataoka H, Cornelissen I, Darragh MR, Hussain A, Zheng YW, Srinivasan Y, Brown C, Xu SM, Regard JB, Lin CY, Craik CS, Kirchhofer D, Coughlin SR
The China connection: Michael Rossmann and his first encounter with me.
1. Protein Cell - published January 1, 2010
2. Wang JH
UHRF1 Links the Histone code and DNA Methylation to ensure Faithful Epigenetic Memory Inheritance.
1. Genet Epigenet - published January 1, 2010
2. Bronner C, Fuhrmann G, Chédin FL, Macaluso M, Dhe-Paganon S