Member Publications

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45 Member Publications for October 2009

Evolution of biological catalysis: ribozyme to RNP enzyme.
1. Cold Spring Harb Symp Quant Biol - published October 24, 2009
2. Cech TR
The structure and conformation of Lys63-linked tetraubiquitin.
1. J Mol Biol - published October 9, 2009
2. Datta AB, Hura GL, Wolberger C
Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element.
1. J Biol Chem - published October 9, 2009
2. Whittle JRR, Schwartz TU
Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
1. Nature - published October 8, 2009
2. Wang Y, Juranek S, Li H, Sheng G, Wardle GS, Tuschl T, Patel DJ
A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation.
1. Sci Transl Med - published October 7, 2009
2. Gesty-Palmer D, Flannery P, Yuan L, Corsino L, Spurney R, Lefkowitz RJ, Luttrell LM
X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin.
1. Biochemistry - published October 6, 2009
2. Gruber TD, Westler WM, Kiessling LL, Forest KT
A distinct structural region of the prokaryotic ubiquitin-like protein (Pup) is recognized by the N-terminal domain of the proteasomal ATPase Mpa.
1. FEBS Lett - published October 6, 2009
2. Sutter M, Striebel F, Damberger FF, Allain FH, Weber-Ban E
Universal architecture of bacterial chemoreceptor arrays.
1. Proc Natl Acad Sci U S A - published October 6, 2009
2. Briegel A, Ortega DR, Tocheva EI, Wuichet K, Li Z, Chen S, Müller A, Iancu CV, Murphy GE, Dobro MJ, Zhulin IB, Jensen GJ
A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane.
1. Proc Natl Acad Sci U S A - published October 6, 2009
2. Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM
The tail of KdsC: conformational changes control the activity of a haloacid dehalogenase superfamily phosphatase.
1. J Biol Chem - published October 3, 2009
2. Biswas T, Yi L, Aggarwal P, Wu J, Rubin JR, Stuckey JA, Woodard RW, Tsodikov OV
How to drive your helicase in a straight line.
1. Cell - published October 3, 2009
2. Pyle AM
Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase.
1. J Biol Chem - published October 2, 2009
2. Liu Q, Graeff R, Kriksunov IA, Jiang H, Zhang B, Oppenheimer N, Lin H, Potter BV, Lee HC, Hao Q
Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays.
1. J Mol Biol - published October 2, 2009
2. Murphy JM, Hansen DF, Wiesner S, Muhandiram DR, Borg M, Smith MJ, Sicheri F, Kay LE, Forman-Kay JD, Pawson T
Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation.
1. EMBO J - published October 2, 2009
2. Ko J, Zhang C, Arac D, Boucard AA, Brunger AT, Südhof TC
[(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel.
1. Biochemistry - published October 2, 2009
2. Chiara DC, Hamouda AK, Ziebell MR, Mejia LA, Garcia G 3rd, Cohen JB
The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA.
1. Biochemistry - published October 2, 2009
2. Brown KL, Basu AK, Stone MP
Structure-based optimization of potent and selective inhibitors of the tyrosine kinase erythropoietin producing human hepatocellular carcinoma receptor B4 (EphB4).
1. J Med Chem - published October 2, 2009
2. Lafleur K, Huang D, Zhou T, Caflisch A, Nevado C
Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1.
1. Proc Natl Acad Sci U S A - published October 2, 2009
2. Zhang H, Liu JH, Yang W, Springer T, Shimaoka M, Wang JH
Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control.
1. J Med Chem - published October 2, 2009
2. Aronov AM, Tang Q, Martinez-Botella G, Bemis GW, Cao J, Chen G, Ewing NP, Ford PJ, Germann UA, Green J, Hale MR, Jacobs M, Janetka JW, Maltais F, Markland W, Namchuk MN, Nanthakumar S, Poondru S, Straub J, ter Haar E, Xie X
Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus.
1. Cell Host Microbe - published October 2, 2009
2. Mehlhop E, Nelson S, Jost CA, Gorlatov S, Johnson S, Fremont DH, Diamond MS, Pierson TC
Mining the B cell repertoire for broadly neutralizing monoclonal antibodies to HIV-1.
1. Cell Host Microbe - published October 2, 2009
2. Kwong PD, Mascola JR, Nabel GJ
Endogenous nitric oxide regulates the recovery of the radiation-resistant bacterium Deinococcus radiodurans from exposure to UV light.
1. Proc Natl Acad Sci U S A - published October 2, 2009
2. Patel BA, Moreau M, Widom J, Chen H, Yin L, Hua Y, Crane BR
Visual impairment in the absence of dystroglycan.
1. J Neurosci - published October 2, 2009
2. Satz JS, Philp AR, Nguyen H, Kusano H, Lee J, Turk R, Riker MJ, Hernández J, Weiss RM, Anderson MG, Mullins RF, Moore SA, Stone EM, Campbell KP
22G-RNAs in transposon silencing and centromere function.
1. Mol Cell - published October 2, 2009
2. Halic M, Moazed D
The role of DNA shape in protein-DNA recognition.
1. Nature - published October 2, 2009
2. Rohs R, West SM, Sosinsky A, Liu P, Mann RS, Honig B
Molecular biology. Rejoice--RNAi for yeast.
1. Science - published October 2, 2009
2. Moazed D
Green tea catechins inhibit angiogenesis through suppression of STAT3 activation.
1. Breast Cancer Res Treat - published October 1, 2009
2. Leong H, Mathur PS, Greene GL
Receptor and substrate interactions of clostridial neurotoxins.
1. Toxicon - published October 1, 2009
2. Brunger AT, Rummel A
Structural mechanisms for regulation of membrane traffic by rab GTPases.
1. Traffic - published October 1, 2009
2. Lee MT, Mishra A, Lambright DG
A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction.
1. J Virol - published October 1, 2009
2. Diaz-Griffero F, Qin XR, Hayashi F, Kigawa T, Finzi A, Sarnak Z, Lienlaf M, Yokoyama S, Sodroski J
The structure and assembly dynamics of plasmid actin AlfA imply a novel mechanism of DNA segregation.
1. J Bacteriol - published October 1, 2009
2. Polka JK, Kollman JM, Agard DA, Mullins RD
Selection and characterization of small molecules that bind the HIV-1 frameshift site RNA.
1. ACS Chem Biol - published October 1, 2009
2. Marcheschi RJ, Mouzakis KD, Butcher SE
Conformational flexibility in immunoglobulin E-Fc 3-4 revealed in multiple crystal forms.
1. J Mol Biol - published October 1, 2009
2. Wurzburg BA, Jardetzky TS
Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus.
1. ACS Chem Biol - published October 1, 2009
2. Swoboda JG, Meredith TC, Campbell J, Brown S, Suzuki T, Bollenbach T, Malhowski AJ, Kishony R, Gilmore MS, Walker S
Crystal structure of a trimeric form of the K(V)7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif.
1. Protein Sci - published October 1, 2009
2. Xu Q, Minor DL Jr
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain.
1. Nature - published October 1, 2009
2. Morinière J, Rousseaux S, Steuerwald U, Soler-López M, Curtet S, Vitte AL, Govin J, Gaucher J, Sadoul K, Hart DJ, Krijgsveld J, Khochbin S, Müller CW, Petosa C
Structural relationships among proteins with different global topologies and their implications for function annotation strategies.
1. Proc Natl Acad Sci U S A - published October 1, 2009
2. Petrey D, Fischer M, Honig B
First-principles study of non-heme Fe(II) halogenase SyrB2 reactivity.
1. J Am Chem Soc - published October 1, 2009
2. Kulik HJ, Blasiak LC, Marzari N, Drennan CL
Selection of inhibitor-resistant viral potassium channels identifies a selectivity filter site that affects barium and amantadine block.
1. PLoS One - published October 1, 2009
2. Chatelain FC, Gazzarrini S, Fujiwara Y, Arrigoni C, Domigan C, Ferrara G, Pantoja C, Thiel G, Moroni A, Minor DL Jr
Promoter recognition by bacterial alternative sigma factors: the price of high selectivity?
1. Genes Dev - published October 1, 2009
2. Feklistov A, Darst SA
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization.
1. Cell - published October 1, 2009
2. Ye X, Wang Y, Cahill H, Yu M, Badea TC, Smallwood PM, Peachey NS, Nathans J
Healthcare reform with a safety net: lessons from San Francisco.
1. Am J Manag Care - published October 1, 2009
2. Bindman AB, Chen A, Fraser JS, Yee HF Jr, Ofman D
Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published October 1, 2009
2. Graña M, Bellinzoni M, Miras I, Fiez-Vandal C, Haouz A, Shepard W, Buschiazzo A, Alzari PM
Expression, purification and preliminary X-ray analysis of the Neisseria meningitidis outer membrane protein PorB.
1. Acta Crystallogr Sect F Struct Biol Cryst Commun - published October 1, 2009
2. Tanabe M, Iverson TM
Arrestin development: emerging roles for beta-arrestins in developmental signaling pathways.
1. Dev Cell - published October 1, 2009
2. Kovacs JJ, Hara MR, Davenport CL, Kim J, Lefkowitz RJ