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69 Member Publications for January

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PARG regulates the proteasomal degradation of TARG1.
1. Cell Rep - published January 6, 2026
2. Groslambert J, Buch-Larsen SC, Hendriks IA, Kurzbauer R, Elsborg JD, Chatrin C, Agnew T, Henfrey C, Tellier M, Prokhorova E, Hoang SM, Barosso-Gonzalez J, O'Sullivan RJ, Clausen T, Nielsen ML, Ahel I
Deletion of tonB1 in Pseudomonas aeruginosa impairs zinc homeostasis and pathogenicity.
1. Appl Environ Microbiol - published January 6, 2026
2. Li W, Zheng Y, Wang G, Cheng J, Xiao W, Ma X, Li P, Chazin WJ, Lin J
Advances in BRET probes for intracellular target engagement studies.
1. Nat Chem Biol - published January 6, 2026
2. Capener JL, Schwalm MP, Vasta JD, Michaud A, Teske KA, Marsiglia WM, Huber KVM, Dar AC, Knapp S, Axtman AD, Robers MB
A neutralizing APOA5 monoclonal antibody reduces amounts of lipoprotein lipase in capillaries and triggers hypertriglyceridemia.
1. Proc Natl Acad Sci U S A - published January 6, 2026
2. Yang Y, Beigneux AP, Lowe TL, Chen YQ, Xie K, Jung H, Tu Y, Yu RG, Scheithauer JL, Mehta S, Wu J, Alvarez L, Davidson WS, Birrane G, Remaley AT, Sviridov D, Ploug M, Zhen EY, Qian Y, Sloan JH, Siegel RW, Konrad RJ, Fong LG, Young SG
Design of solubly expressed miniaturized SMART MHCs.
1. Proc Natl Acad Sci U S A - published January 6, 2026
2. White WL, Bai H, Kim CJ, Jude KM, Sun R, Guerrero L, Han X, Chen X, Chaudhuri A, Bonzanini JE, Sun Y, Onwuka AE, Wang N, Wang C, Nygren PÅ, Li X, Goreshnik I, Allen A, Levine PM, Kueh HY, Jewett MC, Sgourakis NG, Achour A, Garcia KC, Baker D
Tetraspanin TSP-12 and SUP-17/ADAM10 exhibit cell type-specific codependence for trafficking through the Golgi.
1. Proc Natl Acad Sci U S A - published January 6, 2026
2. Liu Z, Williams B, Wang L, Clark FK, Vignogna RC, Fromme JC, Liu J
Memory B cell development in response to mRNA SARS-CoV-2 and nanoparticle immunization in mice.
1. Proc Natl Acad Sci U S A - published January 6, 2026
2. Wiatr M, Wang Z, Canis M, Hernandez B, Gazumyan A, Santos GSS, Shawraz S, Lee S, Bieniasz PD, Hatziioannou T, Muecksch F, Nussenzweig MC
Reproducible Sample Preparation of Virus-Infected Cells for Cryo-FIB/ET Using Manual Plunge Freezing.
1. Bio Protoc - published January 5, 2026
2. Lavoie NR, Heldwein EE
FLARE: A Flow Cytometry-Based Fluorescent Assay for Measuring HSV-1 Nuclear Egress.
1. Bio Protoc - published January 5, 2026
2. Dai B, Polack L, Moores S, Calderon-Zavala AC, Heldwein EE
New targets and procedures for validating the valence geometry of nucleic acid structures.
1. Nucleic Acids Res - published January 5, 2026
2. Černý J, Nicholls RA, Brzezinski D, Berman HM, Gilski M, Joosten RP, Kowiel M, Lawson CL, Moriarty NW, Richardson JS, Schneider B, Vonrhein C, Williams CJ, Jaskólski M, Egli M
Depolymerizable Elastomeric Polyolefin Thermosets with Great Extensibility.
1. ACS Mater Lett - published January 5, 2026
2. Slor G, Khac QO, Julià LR, Ma Y, Stellacci F
Discovery of Coronavirus Main Protease Inhibitors with Enhanced Brain Exposure and Potent Oral Efficacy in SARS-CoV-2 and MERS Infection Models.
1. J Med Chem - published January 5, 2026
2. Lizzadro L, Li J, Taha TY, Degotte G, Detomasi TC, Zapatero-Belinchon FJ, Hantz ER, Huang S, Matsui Y, Henderson WR, McCann JT, Montano M, Rosecrans J, Torres Pomares DF, McGovern BL, Diaz-Tapia R, Benjamin J, Gordon ME, Suazo ID, Settineri NS, Diallo A, Krogan NJ, Shoichet BK, Verba KA, Albrecht R, García-Sastre A, White KM, Ott M, Craik CS, Renslo AR
Division of labor in trypanosome RNA processing and export through expanded Mex67 paralogs.
1. Nucleic Acids Res - published January 5, 2026
2. Obado SO, Fridy PC, Hegedűsová E, van Eeuwen T, Stein ME, Zhang W, Jensen BC, Chung C, Brillantes M, Glover L, Paris Z, Chait BT, Field MC, Rout MP
β-barrels from short macrocyclic peptides.
1. Chem Commun (Camb) - published January 5, 2026
2. Dang VT, Martynowycz MW, McElheny D, Nguyen AI
Pre-assembled complexes and allosteric effects: parallels between eukaryotic phosphorylation cascades and membrane fusion during herpesviral entry.
1. J Virol - published January 5, 2026
2. Gonzalez-Del Pino GL, Heldwein EE
Close-up of vesicular ER exit sites by volume electron imaging using FIB-SEM.
1. J Cell Biol - published January 5, 2026
2. Nair A, Nair A, Stock P, Jain A, Somerville E, Sanyal A, Costa-Filho JI, Kirchhausen T
Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation.
1. J Cell Biol - published January 5, 2026
2. Pinto CS, Bakker SE, Suchenko A, Kolodny IM, Hussain H, Hatano T, Sampath K, Chinthalapudi K, Heissler SM, Mishima M, Balasubramanian M
Towards a unified gating scheme for the CNBD ion channel family.
1. J Gen Physiol - published January 5, 2026
2. Lin JL, Chanda B
Author Correction: Repulsions instruct synaptic partner matching in an olfactory circuit.
1. Nature - published January 4, 2026
2. Li Z, Lyu C, Xu C, Hu Y, Luginbuhl DJ, Caspi-Lebovic AB, Priest JM, Özkan E, Luo L
Bacterial ubiquitin ligase engineered for small molecule and protein target identification.
1. EMBO J - published January 3, 2026
2. Ye JS, Majumdar A, Park BC, Black MH, Hsieh TS, Osinski A, Servage KA, Kulkarni K, Naidoo J, Alto NM, Stratton MM, Alfandari D, Ready JM, Pawłowski K, Tomchick DR, Tagliabracci VS
TRIM2 E3 ligase substrate discovery reveals zinc-mediated regulation of TMEM106B in the endolysosomal pathway.
1. EMBO Rep - published January 3, 2026
2. Perez-Borrajero C, Stein F, Schweimer K, Rettel M, Schwarz JJ, Haberkant P, Lapouge K, Gayk J, Hoffmann T, Bhogaraju S, Noh KM, Savitski M, Mahamid J, Hennig J
Asymmetric envelope surface disposition of secreted protein YjbI controls bimodal antibiotic susceptibilities in C. crescentus.
1. EMBO J - published January 3, 2026
2. Costafrolaz J, Degeorges L, Panis G, Vallet SU, Velasco Gomariz M, Meireles FTP, Dal Peraro M, Fröhlich KS, Viollier PH
Structure and immunogenicity of an engineered soluble prefusion-stabilized EBV gB antigen.
1. Nat Commun - published January 3, 2026
2. McCool RS, Acreman CM, Powell AE, Picucci SI, Stieh DJ, Chou CW, Huynh J, Caruso H, Park S, O'Rear J, Chen JL, Palanski BA, Byrne PO, Sponholtz MR, Kim J, Ledgerwood JE, Weidenbacher PA, McLellan JS
LetA defines a structurally distinct transporter family.
1. Nature - published January 2, 2026
2. Santarossa CC, Li Y, Yousef S, Hasdemir HS, Rodriguez CC, Haase MAB, Baek M, Coudray N, Pavek JG, Focke KN, Silverberg AL, Bautista C, Yeh JT, Marty MT, Baker D, Tajkhorshid E, Ekiert DC, Bhabha G
Shifting the PPARγ conformational ensemble toward a transcriptionally repressive state improves covalent inhibitor efficacy.
1. Elife - published January 2, 2026
2. Arifova L, MacTavish BS, Laughlin Z, Karadi Girdhar MN, Shang J, Li MH, Yu X, Zhu D, Kamenecka TM, Kojetin DJ
Erythrocyte Membrane Protein 3 (EMAP3) Is Exposed on the Surface of the Plasmodium berghei Infected Red Blood Cell.
1. Mol Microbiol - published January 2, 2026
2. Hernandez SRC, Rashpa R, Jonsdottir TK, Paoletta MS, Ter Beek J, Díaz MR, Krol JMM, Chevalley-Maurel S, Ishizaki T, Berntsson RP, Janse CJ, Franke-Fayard B, Brochet M, Bushell ESC
Corrigendum to "E6 Proteins from Diverse Papillomaviruses Self-Associate Both In Vitro and In Vivo" [J. Mol. Biol. 396(1) (2010) 90-104].
1. J Mol Biol - published January 2, 2026
2. Zanier K, Ruhlmann C, Melin F, Masson M, M'hamed Ould Sidi AO, Bernard X, Fischer B, Brino L, Ristriani T, Rybin V, Baltzinger M, Pol SV, Hellwig P, Schultz P, Travé G
Norepinephrine derepresses the Fur regulon of Neisseria gonorrhoeae to enable growth in iron-limited conditions.
1. J Bacteriol - published January 2, 2026
2. Westlake CS, Stoudenmire JL, Bhatia I, Perera YR, Krueger RM, Cornelissen CN, Chazin WJ, Kendall MM, Criss AK
Predicting the protein interaction landscape of a free-living bacterium with pooled-AlphaFold3.
1. Mol Syst Biol - published January 2, 2026
2. Todor H, Kim LM, Jänes J, Burkhart HN, Darst SA, Beltrao P, Gross CA
Structure-Guided Design of Potent and Selective Covalent Inhibitors Targeting the SARS-CoV-2 Papain-like Protease.
1. J Med Chem - published January 2, 2026
2. Sharafi M, Teh WP, Green J, Charifson PS, Wang J, Pemberton OA, Nevins AM, Lye M, Liu X, Varca AC, Owen CD, Morsheimer K, Wacquiez A, Dawson C, Steuber C, Smith J, Girardi NM, Magin RS, Marto JA, Saeed M, Davey RA, Hardee D, Ng TI, Namchuk MN, Buhrlage SJ
Poxvirus dsDNA genomes differentially activate AIM2 or NLRP3 inflammasomes in human primary cells.
1. EMBO J - published January 2, 2026
2. Tesfamariam YM, Christensen MH, Diehl S, Klein T, Lingnau JM, Normann S, Hagelauer E, Herbert M, Reimer S, Joshi RP, Engels P, Pritzl S, Fontana P, Zillinger T, Hartmann G, Eis-Hübinger A, Lam MC, Walgenbach KJ, Meissner F, Wu H, Schmidt FI
SpatialDINO: A Self-Supervised 3D Vision Transformer that enables Segmentation and Tracking in Crowded Cellular Environments.
1. bioRxiv - published January 2, 2026
2. Lavaee A, Jain A, Scanavachi Moreira Campos G, Costa-Filho JI, Ingemansson A, Kirchhausen T
Quantitative Degradation Rate Assessment of bioPROTACs Based on Peptide Degrons, E3 Domains, Adapters and Conjugated Small Molecules.
1. ACS Chem Biol - published January 2, 2026
2. Vukovic D, Winkelvoß D, Udovcic A, Riermeier L, Jaime-Figueroa S, Crews CM, Plückthun A
LPS-induced structural reorganization and polymerization drive noncanonical inflammasome activation.
1. Sci Adv - published January 2, 2026
2. Wang C, Lacey P, Tian T, Teran E, Liaqat M, Shivcharan S, Shumba P, He J, Rathinam VA, Wysocki VH, Ruan J
The long noncoding RNA VIM-AS1 and nucleoporin Nup358/RanBP2 regulate SMAD nuclear accumulation during TGF-β signaling.
1. Nucleic Acids Res - published January 1, 2026
2. Rodrigues-Junior DM, Ali MM, Itoh Y, Ferreira MS, Heldin J, Fu H, Hoelz A, Heldin CH, Moustakas A
Developing and Demonstrating a Lab Method for Quantifying Hair Exposure to Environmental Tobacco Smoke with a Forensic Perspective.
1. J Chem Educ - published January 1, 2026
2. Jones TZ, Trejo CJ, Mohammadi S, Sharifan H
Structural analysis of OCT4 binding to human LIN28B nucleosomes.
1. Sci Rep - published January 1, 2026
2. Sinha KK, Halic M
Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity.
1. Nat Commun - published January 1, 2026
2. Schwartz I, Budroni V, Meyenberg M, Hodakova Z, Hornegger H, Hacker K, Schwartz S, Grabarczyk DB, Ehrmann JF, Scinicariello S, Haselbach D, Menche J, Clausen T, Karagöz GE, Versteeg GA
Structural basis for inhibition of SpyCas9 by the anti-CRISPR protein AcrIIA26.
1. Biochem J - published January 1, 2026
2. Bailey S, Zheng I, Learn B
Crystal structure of apo human spermidine synthase reveals dynamic rearrangement at the active site.
1. Struct Dyn - published January 1, 2026
2. Fagbohun OO, Canfield MA, Clinger JA
Cinnamic acid induces neurodevelopmental defects via PPARγ signaling in zebrafish.
1. Chem Biol Interact - published January 1, 2026
2. Peng L, Wang H, Li Y, Liu X, Chang K, Yi W, Wang B, Zeng N, Li Z, Wu C
Monoclonal antibodies for Mpox: protective targets and therapeutic potential.
1. Curr Opin HIV AIDS - published January 1, 2026
2. Guardado-Calvo P, Freund NT, Coelho CH
A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein.
1. Cell Rep Med - published January 1, 2026
2. Abu-Shmais AA, Guo L, Khalil AM, Leonard SE, Miller RJ, Janke AK, Vukovich MJ, Bass LE, Suresh YP, Rush SA, Wolters RM, Kose N, Carnahan RH, Crowe JE Jr, Bonami RH, Mousa JJ, McLellan JS, Georgiev IS
Decoding the interconnected splicing patterns of hepatitis B virus and host using large language and deep learning models.
1. Microb Genom - published January 1, 2026
2. Lim CS, Brown CM
The structure of a thermostable phage's portal vertex and neck complex illuminates the headful maturation mechanism.
1. J Mol Biol - published January 1, 2026
2. Sedivy EL, Agnello E, Hobaugh JE, Ahsan R, Song K, Xu C, Kelch BA
The cotranslational cycle of the ribosome-bound Hsp70 homolog Ssb.
1. Nat Commun - published January 1, 2026
2. Zhang Y, Grundmann L, Vollmar L, Schimpf J, Hübscher V, Areeb M, Grishkovskaya I, Moddemann A, Werner K, Hugel T, Haselbach D, Rospert S
Cooperativity and communication between the active sites of the dimeric SARS-CoV-2 main protease.
1. Sci Adv - published January 1, 2026
2. Zvornicanin SN, Shaqra AM, Flynn J, Intravaia LE, Martinez HC, Jia W, Gupta DK, Moquin S, Dovala D, Bolon DN, Kelch BA, Schiffer CA, Yilmaz NK
Cryo-EM structure of the vaccinia virus entry fusion complex reveals a multicomponent fusion machinery.
1. Sci Adv - published January 1, 2026
2. Lin CS, Li CA, Wang CH, Kao CF, Chiu HJ, Yeh MC, Gao HD, Ho MC, Lee HM, Chang W
Poly(ADP-ribose) glycohydrolase enforces p21 degradation via dePARylation to promote gastric cancer progression.
1. J Clin Invest - published January 1, 2026
2. Hu Y, Bao Q, Huang Y, Wang Y, Zhao X, Nan J, Meng Y, Deng M, Li Y, Zhuang Z, He H, Zu D, Zhong Y, Zhang C, Wang B, Li R, He Y, Wang Q, Liu M, Tainer JA, Shi Y, Cheng X, Jing J, Ye Z
Insights from aquaporin structures into drug-resistant sleeping sickness.
1. Elife - published January 1, 2026
2. Matusevicius M, Corey RA, Gragera M, Yamashita K, Sprenger T, Ungogo M, Blaza JN, Castro-Hartmann P, Chirgadze DY, Chaitanya Vedithi S, Afanasyev P, Melero R, Warshamanage R, Gusach A, Carazo JM, Carrington M, Blundell T, Murshudov GN, Stansfeld PJ, Sansom MSP, De Koning HP, Tate CG, Weyand S
Transcription co-inhibition alters drug resistance evolution and enhances Mycobacterium tuberculosis clearance from granulomas.
1. Nat Microbiol - published January 1, 2026
2. Bosch B, Munsamy-Govender V, Sarathy J, Lilic M, Olinares PDB, Eckartt KA, Nalam P, Lang M, Simon M, Richter A, Rock JM, Campbell EA
A Modular Vaccine Platform Against SARS-CoV-2 Based on Self-Assembled Protein Nanoparticles.
1. Adv Sci (Weinh) - published January 1, 2026
2. Lee S, Jang Y, Kim Y, Shin Y, Song JJ, Kim M, Jon S
Autopalmitoylation of IDH1-R132H regulates its neomorphic activity in cancer cells.
1. Nat Chem Biol - published January 1, 2026
2. Hu L, Lin J, Sun L, Berezuk AM, Tuttle KS, Zhu X, Seo HS, Dhe-Paganon S, Li P, Sun Y, Ni L, Zhang J, Tan D, Wakimoto H, Cahill DP, Bai X, Luo X, Asara JM, Subramaniam S, Shan Y, Wu X
PDX1 phosphorylation at S61 by mTORC1 links nutrient signaling to β cell function and metabolic disease.
1. Cell Rep - published January 1, 2026
2. Fan J, Zhang X, Zhang J, Zhao T, Burley SK, Zheng XFS
Microgravity reshapes bacteriophage-host coevolution aboard the International Space Station.
1. PLoS Biol - published January 1, 2026
2. Huss P, Chitboonthavisuk C, Meger A, Nishikawa K, Oates RP, Mills H, Holzhaus O, Raman S
The pathway-independent positive allosteric modulator C1 allows for the identification of active Y(4) receptor relevant positions.
1. Cell Mol Life Sci - published January 1, 2026
2. Schüß C, Vu O, Pelczyk T, Schubert M, Du Y, Stichel J, Weaver CD, Meiler J, Beck-Sickinger AG
A general one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging.
1. Nat Commun - published January 1, 2026
2. Roßmann K, Pabst U, Baciu BC, Sun S, Huhn C, Olesen CH, Kowald M, Tapp E, Bieck M, Birke R, Shields BC, Jeong P, Hong J, Tadross MR, Levitz J, Lehmann M, Lipstein N, Broichhagen J
EPOP restricts PRC2.1 targeting to chromatin by directly modulating enzyme complex dimerization.
1. Nat Commun - published January 1, 2026
2. Gong L, Liu X, Yang X, Yu Z, Bhat MY, Chen S, Lemoff A, Xing C, Liu X
Bridging the gap: When transcription meets translation.
1. FEBS J - published January 1, 2026
2. Rahil H, Weixlbaumer A
Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines.
1. Environ Toxicol - published January 1, 2026
2. Hart LN, Lev KL, Hefferan S, Premathilaka SH, Thenuwara SI, Isailovic D, Sherman DH, Dick GJ
Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors.
1. Nat Commun - published January 1, 2026
2. Bonsor DA, Finci LI, Potter JR, Young LC, Wall VE, Goldstein de Salazar R, Geis KR, Stephens T, Finney J, Nissley DV, McCormick F, Simanshu DK
T Cell Assay to Track Presentation of an Influenza Hemagglutinin Epitope Presented by the MHC-II Protein HLA-DR1.
1. Methods Mol Biol - published January 1, 2026
2. Ramesh KM, Lu L, Stern LJ
License to Replicate: Mechanisms of Licensing Eukaryotic Origins for DNA Replication.
1. Bioessays - published January 1, 2026
2. Frisbie V, Bleichert F
An open axial channel of the AAA ClpXP protease enhances degradation of specific classes of protein substrates.
1. Protein Sci - published January 1, 2026
2. Lyu Y, Bolstad I, Davis JH, Sauer RT, Ghanbarpour A
Structural and functional specialization of Bordetella pertussis DsbA for pertussis toxin folding.
1. Protein Sci - published January 1, 2026
2. Penning S, Mitchell L, Hong Y, Cunliffe T, Subedi P, Wang G, Hor L, Totsika M, Paxman JJ, Heras B
Dynamic interaction of the Yersinia pseudotuberculosis type three secretion system proteins LcrV and LcrG.
1. Protein Sci - published January 1, 2026
2. Mangu JCK, Rogne P, Mattsson J, Hultgren L, Gahlot KD, Lamy A, Berntsson RP, Johansson LB, Francis MS, Wolf-Watz M
Assessing the validity of leucine zipper constructs predicted by AlphaFold.
1. Protein Sci - published January 1, 2026
2. Mitic I, Rowell K, Litfin T, Michie KA, Jacques DA
Design and characterization of calprotectin tetramerization variants for probing the role of oligomerization in receptor activation.
1. Protein Sci - published January 1, 2026
2. Garcia V, D'Souza A, Kozlyuk N, Perera YR, Damo SM, Chazin WJ
In Memoriam: Professor Ruth Ann Austad Altschuld (1940-2025).
1. Protein J - published January 1, 2026
2. Narayan P, Berliner LJ, Narayan M