Member Publications
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80 Member Publications for February
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Advancing structure modeling from cryo-EM maps with deep learning.
- Biochem Soc Trans - published February 7, 2025
- Li S, Terashi G, Zhang Z, Kihara D
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Single-stranded DNA binding to the transcription factor PafBC triggers the mycobacterial DNA damage response.
- Sci Adv - published February 7, 2025
- Schilling CM, Zdanowicz R, Rabl J, Müller AU, Boehringer D, Glockshuber R, Weber-Ban E
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The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation.
- Nat Commun - published February 7, 2025
- Blake KS, Xue YP, Gillespie VJ, Fishbein SRS, Tolia NH, Wencewicz TA, Dantas G
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Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha.
- RSC Chem Biol - published February 6, 2025
- Xu Z, Sinha A, Pandya DN, Schnicker NJ, Wadas TJ
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Concurrent and consolidative carboplatin plus nab-paclitaxel or paclitaxel in locally advanced NSCLC A multicenter, randomized clinical trial.
- Int J Radiat Oncol Biol Phys - published February 6, 2025
- Zhang Y, Laine AM, Iyengar P, Westover KD, Dowell JE, Hughes RS, Christie A, Mickel T, Attia A, Villaruz L, Chen Y, Spigel DR, Socinski MA, Timmerman RD, Gerber DE
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Determination of Pseudomonas aeruginosa MexXY-OprM substrate profile in a major efflux knockout system reveals distinct antibiotic substrate classes.
- Microbiol Spectr - published February 6, 2025
- Kavanaugh LG, Hariharan SM, Conn GL
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Structural mapping of polyclonal IgG responses to HA after influenza virus vaccination or infection.
- mBio - published February 6, 2025
- León AN, Rodriguez AJ, Richey ST, Torrents de la Pena A, Wolters RM, Jackson AM, Webb K, Creech CB, Yoder S, Mudd PA, Crowe JE Jr, Han J, Ward AB
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C10-Benzoate Esters of Anhydrotetracycline Inhibit Tetracycline Destructases and Recover Tetracycline Antibacterial Activity.
- ACS Infect Dis - published February 6, 2025
- Williford EE, Xue YP, Tang WK, Li R, Jones KV, Blake KS, Blaine HC, Lian X, Stallings CL, Tolia NH, Dantas G, Wencewicz TA
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Electrosome assembly: Structural insights from high voltage-activated calcium channel (CaV)-chaperone interactions.
- Biochem Soc Trans - published February 6, 2025
- Chen Z, Minor DL Jr
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Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter.
- Elife - published February 6, 2025
- Goyal P, Dhanabalan K, Scalise M, Friemann R, Indiveri C, Dobson RCJ, Vinothkumar KR, Ramaswamy S
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High-resolution Cryo-EM Structure Determination of a-Synuclein-A Prototypical Amyloid Fibril.
- Bio Protoc - published February 5, 2025
- Sanchez JC, Pierson JA, Borcik CG, Rienstra CM, Wright ER
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Nano-Polymers as Cas9 Inhibitors.
- Polymers (Basel) - published February 5, 2025
- Chepurna O, Chatterjee A, Li Y, Ding H, Murali R, Black KL, Sun T
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Coordination between ESCRT function and Rab conversion during endosome maturation.
- EMBO J - published February 5, 2025
- Ott DP, Desai S, Solinger JA, Kaech A, Spang A
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Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis.
- Cell Metab - published February 4, 2025
- Liu R, Ren X, Park YE, Feng H, Sheng X, Song X, AminiTabrizi R, Shah H, Li L, Zhang Y, Abdullah KG, Dubois-Coyne S, Lin H, Cole PA, DeBerardinis RJ, McBrayer SK, Huang H, Zhao Y
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Zinc-limited Mycobacterium tuberculosis stimulate distinct responses in macrophages compared with standard zinc-replete bacteria.
- Infect Immun - published February 4, 2025
- Marcantonio E, Burger AD, Chang KH, Hoffmann FW, Fu Y, Khadka VS, Smagghe BJ, Deng Y, Hoffmann PR, Prisic S
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A universal method for the purification of C2H2 zinc finger arrays.
- PLoS One - published February 4, 2025
- Liang J, Azubel M, Wang G, Nie Y, Kornberg RD, Beel AJ, Mattei PJ
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Increasing the Efficiency of Ensemble Molecular Dynamics Simulations with Termination of Unproductive Trajectories Identified at Runtime.
- J Phys Chem A - published February 4, 2025
- Marquez J, Cuendet MA, Caino-Lores S, Estrada T, Deelman E, Weinstein H, Taufer M
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Role of sortase-assembled Ebp pili in Enterococcus faecalis adhesion to iron oxides and its impact on extracellular electron transfer.
- Microbiol Spectr - published February 4, 2025
- Ho FK, Lam LN, Matysik A, Watts TD, Wong JJ, Chong KKL, Choo PY, Tolar J, Low PM, Chua ZS, Paxman JJ, Heras B, Marsili E, Ajo-Franklin CM, Kline KA
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Design of a light and Ca(2+) switchable organic-peptide hybrid.
- Proc Natl Acad Sci U S A - published February 4, 2025
- Khaleel ZH, No YH, Kim NH, Bae DH, Wu Y, Kim S, Choi H, Lee DE, Jeong SY, Ko YJ, Kim SG, Suh M, Kim JC, DeGrado WF, Kim KH, Kim YH
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Serine phosphorylation facilitates protein degradation by the human mitochondrial ClpXP protease.
- Proc Natl Acad Sci U S A - published February 4, 2025
- Feng Y, Goncalves MM, Jitkova Y, Keszei AFA, Yan Y, Sarathy C, St-Germain J, Kenney TMG, Tcheng M, Trudel V, Mancini RS, Upadhyay R, Hurren R, Gronda M, Schultz M, Soriano K, Lees K, Pomroy NC, Currie SQW, Privé GG, Reed MA, Yudin AK, Penn LZ, Arrowsmith CH, Raught B, Mazhab-Jafari MT, Vahidi S, Schimmer AD
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The chloroplast RNA-binding protein CP29A supports rbcL expression during cold acclimation.
- Proc Natl Acad Sci U S A - published February 4, 2025
- Lenzen B, Rösch F, Legen J, Ruwe H, Kachariya N, Sattler M, Small I, Schmitz-Linneweber C
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How can we make sound replication decisions?
- Proc Natl Acad Sci U S A - published February 4, 2025
- Davis-Stober CP, Sarafoglou A, Aczel B, Chandramouli SH, Errington TM, Field SM, Fishbach A, Freire J, Ioannidis JPA, Oberauer K, Pestilli F, Ressl S, Schad DJ, Ter Schure J, Tentori K, van Ravenzwaaij D, Vandekerckhove J, Gundersen OE
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Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution.
- Cell - published February 3, 2025
- Hsu AY, Huang Q, Pi X, Fu J, Raghunathan K, Ghimire L, Balasubramanian A, Xie X, Yu H, Loison F, Haridas V, Zha J, Liu F, Park SY, Bagale K, Ren Q, Fan Y, Zheng Y, Cancelas JA, Chai L, Stowell SR, Chen K, Xu R, Wang X, Xu Y, Zhang L, Cheng T, Ma F, Thiagarajah JR, Wu H, Feng S, Luo HR
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Combinatorial mapping of E3 ubiquitin ligases to their target substrates.
- Mol Cell - published February 3, 2025
- Suiter CC, Calderon D, Lee DS, Chiu M, Jain S, Chardon FM, Lee C, Daza RM, Trapnell C, Zheng N, Shendure J
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The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition.
- Structure - published February 3, 2025
- Kennedy AE, Barczewski AH, Arnoldy CR, Pennington JP, Tiernan KA, Hidalgo MB, Reilly CC, Wongsri T, Ragusa MJ, Grigoryan G, Mierke DF, Pellegrini M
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Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3' End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute-2 PAZ Domain.
- J Med Chem - published February 3, 2025
- Das RS, Datta D, Brown CR, Gilbert JA, Chan A, Willoughby J, Gupta S, Kim M, Degaonkar R, Racie T, Lei L, Schlegel MK, Castoreno A, Charisse K, Rajeev KG, Egli M, Manoharan M
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Deletion of ESX-3 and ESX-4 secretion systems in Mycobacterium abscessus results in highly impaired pathogenicity.
- Commun Biol - published February 3, 2025
- Daher W, Le Moigne V, Tasrini Y, Parmar S, Sexton DL, Aguilera-Correa JJ, Berdal V, Tocheva EI, Herrmann JL, Kremer L
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Aerolysin Nanopore Structures Revealed at High Resolution in a Lipid Environment.
- J Am Chem Soc - published February 3, 2025
- Anton JS, Iacovache I, Bada Juarez JF, Abriata LA, Perrin LW, Cao C, Marcaida MJ, Zuber B, Dal Peraro M
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The assembly factor Reh1 is released from the ribosome during its initial round of translation.
- Nat Commun - published February 3, 2025
- Musalgaonkar S, Yelland JN, Chitale R, Rao S, Ozadam H, Taylor DW, Cenik C, Johnson AW
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Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP((1,2)) in a position elevated from the virion membrane.
- Nat Commun - published February 3, 2025
- Hastie KM, Salie ZL, Ke Z, Halfmann PJ, DeWald LE, McArdle S, Grinyó A, Davidson E, Schendel SL, Hariharan C, Norris MJ, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook MR, Doranz B, Crozier I, Kawaoka Y, Branco LM, Kuhn JH, Briggs JAG, Worwa G, Davis CW, Ahmed R, Saphire EO
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Neuronal constitutive endolysosomal perforations enable α-synuclein aggregation by internalized PFFs.
- J Cell Biol - published February 3, 2025
- Sanyal A, Scanavachi G, Somerville E, Saminathan A, Nair A, Bango Da Cunha Correia RF, Aylan B, Sitarska E, Oikonomou A, Hatzakis NS, Kirchhausen T
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Structural basis of aquaporin-4 autoantibody binding in neuromyelitis optica.
- Sci Adv - published February 2, 2025
- Gupta M, Khandelwal NK, Nelson A, Hwang P, Pourmal S, Bennett JL, Stroud RM
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De Novo Design of Proteins That Bind Naphthalenediimides, Powerful Photooxidants with Tunable Photophysical Properties.
- J Am Chem Soc - published February 2, 2025
- Mann SI, Lin Z, Tan SK, Zhu J, Widel ZXW, Bakanas I, Mansergh JP, Liu R, Kelly MJS, Wu Y, Wells JA, Therien MJ, DeGrado WF
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MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation.
- Mol Oncol - published February 2, 2025
- Guérin C, Vinchent A, Fernandes M, Damour I, Laratte A, Tellier R, Estevam GO, Meneboo JP, Villenet C, Descarpentries C, Fraser JS, Figeac M, Cortot AB, Rouleau E, Tulasne D
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A FAIR-Compliant Management Solution for Molecular Simulation Trajectories.
- J Chem Inf Model - published February 2, 2025
- Vitalis A, Winkler S, Zhang Y, Widmer J, Caflisch A
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Haspin kinase binds to a nucleosomal DNA supergroove.
- Nat Struct Mol Biol - published February 2, 2025
- Hicks CW, Gliech CR, Rahman S, Zhang X, Eneim AS, Vasquez SJ, Holland AJ, Wolberger C
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Development of Zafirlukast Analogues for Improved Antithrombotic Activity Through Thiol Isomerase Inhibition.
- Arterioscler Thromb Vasc Biol - published February 2, 2025
- Keovilay JA, Howard KC, Taylor KA, Khan S, Wurl SE, Szahaj MK, Sage T, Chandrika NT, Hou C, Tsodikov OV, Gibbins JM, Garneau-Tsodikova S, Kennedy DR
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Structural dynamics of human fatty acid synthase in the condensing cycle.
- Nature - published February 2, 2025
- Choi W, Li C, Chen Y, Wang Y, Cheng Y
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Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes.
- Sci Adv - published February 2, 2025
- Grau B, Kormos R, Bañó-Polo M, Chen K, García-Murria MJ, Hajredini F, Sánchez Del Pino MM, Jo H, Martínez-Gil L, von Heijne G, DeGrado WF, Mingarro I
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Integrative analysis of KCNQ1 variants reveals molecular mechanisms of type 1 long QT syndrome pathogenesis.
- Proc Natl Acad Sci U S A - published February 2, 2025
- Brewer KR, Vanoye CG, Huang H, Clowes Moster KR, Desai RR, Hayes JB, Burnette DT, George AL, Sanders CR
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MERS-CoV spike vaccine-induced N-terminal domain-specific antibodies are more protective than receptor binding domain-specific antibodies.
- iScience - published February 2, 2025
- Abiona OM, Wang N, Leist SR, Schäfer A, Cockrell AS, Wang L, Bangaru S, Stevens L, Graham RL, Kocher JF, Tsybovsky Y, Kanekiyo M, Kumar A, Morabito KM, Rosen O, Shi W, Werner A, Zhang Y, Ziwawo C, Dzuvor CKO, Palandjian C, Eastman C, Matthews HR, Joseph J, Chappell JD, Kong WP, Mascola JR, Ward AB, Denison MR, Baric R, McLellan JS, Graham BS, Corbett-Helaire KS
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Modelling a pathological GSX2 variant that selectively alters DNA binding reveals hypomorphic mouse brain defects.
- Dis Model Mech - published February 1, 2025
- Tweedie L, Riccetti MR, Cain B, Qin S, Salomone J, Webb JA, Riesenberg A, Ehrman LA, Waclaw RR, Kovall RA, Gebelein B, Campbell K
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Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread.
- Sci Transl Med - published February 1, 2025
- Pahmeier F, Monticelli SR, Feng X, Hjorth CK, Wang A, Kuehne AI, Bakken RR, Batchelor TG, Lee SE, Middlecamp M, Stuart L, Duarte-Neto AN, Abelson DM, McLellan JS, Biering SB, Herbert AS, Chandran K, Harris E
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A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma.
- Sci Transl Med - published February 1, 2025
- Rendo V, Lee EQ, Bossi C, Khuu N, Rudek MA, Pal S, Azazmeh N, Rashid R, Lin JR, Cusick M, Reynolds ARN, Fassinou ACR, Ayoub G, Malinowski S, Lapinskas E, Pisano W, Jeang J, Stopka SA, Regan MS, Spetz J, Desai A, Lieberman F, Palanichamy K, Fisher JD, Pelton K, Huang RY, Sarosiek KA, Nabors LB, Holdhoff M, Danda N, Strowd R, Desideri S, Walbert T, Ye X, Chakravarti A, Sorger PK, Santagata S, Agar NYR, Grossman SA, Alexander BM, Wen PY, Ligon KL, Beroukhim R
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Conformational variants of I-A(k) MHC class II molecules carry distinct immunopeptidomes.
- Mol Immunol - published February 1, 2025
- Drake LA, Ramos RB, Denzin LK, Nanaware PP, Stern LJ, Drake JR
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Integration of New Approach Methods for the Assessment of Data Poor Chemicals.
- Toxicol Sci - published February 1, 2025
- Paul Friedman K, Thomas RS, Wambaugh JF, Harrill JA, Judson RS, Shafer TJ, Williams AJ, Lee JJ, Loo LH, Gagné M, Long AS, Barton-Maclaren TS, Whelan M, Bouhifd M, Rasenberg M, Simanainen U, Sobanski T
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Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel.
- Nat Commun - published February 1, 2025
- Agarwal S, Kim ED, Lee S, Simon A, Accardi A, Nimigean CM
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Reprogrammable RNA-targeting CRISPR systems evolved from RNA toxin-antitoxins.
- Cell - published February 1, 2025
- Zilberzwige-Tal S, Altae-Tran H, Kannan S, Wilkinson ME, Vo SC, Strebinger D, Edmonds KK, Yao CJ, Mears KS, Shmakov SA, Makarova KS, Macrae RK, Koonin EV, Zhang F
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Capsid transfer of the retrotransposon Copia controls structural synaptic plasticity in Drosophila.
- PLoS Biol - published February 1, 2025
- M'Angale PG, Lemieux A, Liu Y, Wang S, Zinter M, Alegre G, Simkin A, Budnik V, Kelch BA, Thomson T
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Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST.
- Cell Metab - published February 1, 2025
- Sprenger HG, Mittenbühler MJ, Sun Y, Van Vranken JG, Schindler S, Jayaraj A, Khetarpal SA, Smythers AL, Vargas-Castillo A, Puszynska AM, Spinelli JB, Armani A, Kunchok T, Ryback B, Seo HS, Song K, Sebastian L, O'Young C, Braithwaite C, Dhe-Paganon S, Burger N, Mills EL, Gygi SP, Paulo JA, Arthanari H, Chouchani ET, Sabatini DM, Spiegelman BM
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Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses.
- Protein Cell - published February 1, 2025
- Xue L, Chang T, Gui J, Li Z, Zhao H, Zou B, Lu J, Li M, Wen X, Gao S, Zhan P, Rong L, Feng L, Gong P, He J, Chen X, Xiong X
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Rhodamine6G and Hœchst33342 narrow BmrA conformational spectrum for a more efficient use of ATP.
- Nat Commun - published February 1, 2025
- Gobet A, Moissonnier L, Zarkadas E, Magnard S, Bettler E, Martin J, Terreux R, Schoehn G, Orelle C, Jault JM, Falson P, Chaptal V
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Adapting a Trapped Ion Mobility Spectrometry-Q-TOF for High m/z Native Mass Spectrometry and Surface-Induced Dissociation.
- Anal Chem - published February 1, 2025
- Lin YF, Jones BJ, Ridgeway ME, Panczyk EM, Somogyi A, Kaplan DA, Marathe I, Yun S, Kirby KA, Sarafianos SG, Laganowsky AD, Park MA, Wysocki VH
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Removal of Homogeneous Broadening from (1)H-Detected Multidimensional Solid-State NMR Spectra.
- Anal Chem - published February 1, 2025
- Perras FA, Wang S, Mayer J, Halder M, Paterson AL, Culver DB, Rienstra CM
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Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning.
- Elife - published February 1, 2025
- Estevam GO, Linossi E, Rao J, Macdonald CB, Ravikumar A, Chrispens KM, Capra JA, Coyote-Maestas W, Pimentel H, Collisson EA, Jura N, Fraser JS
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Fragment-Based Approach for Hierarchical Nanotube Assembly of Small Molecules in Aqueous Phase.
- Chemistry - published February 1, 2025
- Zia A, Yi M, Liu Z, Wang F, Xu B
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CryoEM structures of Kv1.2 potassium channels, conducting and non-conducting.
- Elife - published February 1, 2025
- Wu Y, Yan Y, Yang Y, Bian S, Rivetta A, Allen K, Sigworth FJ
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How Ligands Achieve Biased Signaling toward Arrestins.
- Biochemistry - published February 1, 2025
- Jiang Q, Che T
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Mechanism of dimer selectivity and binding cooperativity of BRAF inhibitors.
- Elife - published February 1, 2025
- Clayton J, Romany A, Matenoglou E, Gavathiotis E, Poulikakos PI, Shen J
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Genome-wide transcriptome differences associated with perceived discrimination in an urban, community-dwelling middle-aged cohort.
- FASEB J - published February 1, 2025
- Pacheco NL, Noren Hooten N, Wu SF, Mensah-Bonsu M, Zhang Y, Chitrala KN, De S, Mode NA, Ezike N, Beatty Moody DL, Zonderman AB, Evans MK
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Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations.
- Nature - published February 1, 2025
- Xie X, Zhang O, Yeo MJR, Lee C, Tao R, Harry SA, Payne NC, Nam E, Paul L, Li Y, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB
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VARP binds SNX27 to promote endosomal supercomplex formation on membranes.
- Sci Adv - published February 1, 2025
- Chandra M, Kendall AK, Ford MGJ, Jackson LP
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UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.
- Nature - published February 1, 2025
- Yeo MJR, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Nguyen K, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Carr SA, Udeshi ND, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N
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Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies.
- Structure - published February 1, 2025
- Ketaren NE, Fridy PC, Malashkevich V, Sanyal T, Brillantes M, Thompson MK, Oren DA, Bonanno JB, Šali A, Almo SC, Chait BT, Rout MP
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Self-supervised machine learning methods for protein design improve sampling but not the identification of high-fitness variants.
- Sci Adv - published February 1, 2025
- Ertelt M, Moretti R, Meiler J, Schoeder CT
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Structural basis of disease mutation and substrate recognition by the human SLC2A9 transporter.
- Proc Natl Acad Sci U S A - published February 1, 2025
- Khandelwal NK, Gupta M, Kumar P, Balasubramani SG, Echeverria I, Stroud RM
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Structural and kinetic analysis of distinct active and inactive states of Burkholderia cenocepacia orotate phosphoribosyltransferase.
- Arch Biochem Biophys - published February 1, 2025
- Sharma N, Turlington ZR, Zupko SP, Catoggio MN, Lukacs CM, Serbzhinskiy D, Abendroth J, Edwards TE, Lorimer DD, Barrera G, Willis S, Beyer O, Toay S, Da Li T, Torelli AT, Hicks KA, French JB
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Distinct Acyl Carrier Protein Docking Sites Help Mediate the Opposite Stereoselectivities of A- and B-type Modular Polyketide Synthase Ketoreductases.
- Biochemistry - published February 1, 2025
- Ray KA, Lin SN, Keatinge-Clay AT
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In-clinic vitreous biopsy peel pack technique.
- Int J Retina Vitreous - published February 1, 2025
- DeBoer C, Zhao C, Mruthyunjaya P, Mahajan VB, Wai KM, Sanislo SR
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Initiation of ERAD by the bifunctional complex of Mnl1/Htm1 mannosidase and protein disulfide isomerase.
- Nat Struct Mol Biol - published February 1, 2025
- Zhao D, Wu X, Rapoport TA
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The Mutually Inspiring Biological and Chemical Synthesis of Fungal Bicyclo[2.2.2]diazaoctane Indole Alkaloids.
- Chem Rev - published February 1, 2025
- Du L, Dian L, Newmister SA, Xia Y, Luo G, Sherman DH, Li S
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TRiC Is a Structural Component of Mammalian Sperm Axonemes.
- Cytoskeleton (Hoboken) - published February 1, 2025
- Brown A, Leung MR, Zeev-Ben-Mordehai T, Zhang R
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Optimizing In Situ Proximity Ligation Assays for Mitochondria, ER, or MERC Markers in Skeletal Muscle Tissue and Cells.
- Curr Protoc - published February 1, 2025
- Crabtree A, Le H, Harris C, Oliver A, Barillas A, Moore J, Nguyen DN, Rabago IM, Rodriguez B, Stephens DC, Beasley HK, Garza-Lopez E, Neikirk K, Mungai M, Vang L, Vue Z, Vue N, Marshall AG, Turner K, Shao J, Murray S, Gaddy JA, Wanjalla C, Davis J, Damo S, Hinton AO Jr
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Creating Optimal Western Blot Conditions for OPA1 Isoforms in Skeletal Muscle Cells and Tissue.
- Curr Protoc - published February 1, 2025
- Mungai M, Crabtree A, Le H, Moore J, Nguyen D, Rodriguez B, Harris C, Stephens DC, Beasley HK, Garza-Lopez E, Neikirk K, Shao B, Oliver A, Wilson G, Bacevac S, Vang L, Vue Z, Vue N, Marshall AG, Turner K, Zaganjor E, Shao J, Murray S, Gaddy JA, Wanjalla C, Davis J, Damo SM, Banks LD, Hinton A Jr
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The C2 domain augments Ras GTPase-activating protein catalytic activity.
- Proc Natl Acad Sci U S A - published February 1, 2025
- Paul ME, Chen D, Vish KJ, Lartey NL, Hughes E, Freeman ZT, Saunders TL, Stiegler AL, King PD, Boggon TJ
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Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition.
- Cancer Res - published February 1, 2025
- Madorsky Rowdo FP, Martini R, Ackermann SE, Tang CP, Tranquille M, Irizarry A, Us I, Alawa O, Moyer JE, Sigouros M, Nguyen J, Al Assaad M, Cheng E, Ginter PS, Manohar J, Stonaker B, Boateng R, Oppong JK, Adjei EK, Awuah B, Kyei I, Aitpillah FS, Adinku MO, Ankomah K, Osei-Bonsu EB, Gyan KK, Hoda S, Newman L, Mosquera JM, Sboner A, Elemento O, Dow LE, Davis MB, Martin ML
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Structural insights into the role of the prosegment binding loop in a papain-superfamily cysteine protease from Treponema denticola.
- Acta Crystallogr F Struct Biol Commun - published February 1, 2025
- Clark ND, Li C, Malkowski MG
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Serendipitous high-resolution structure of Escherichia coli carbonic anhydrase 2.
- Acta Crystallogr F Struct Biol Commun - published February 1, 2025
- Rankin MR, Smith JL
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Male-male interactions shape mate selection in Drosophila.
- Cell - published February 1, 2025
- Hindmarsh Sten T, Li R, Hollunder F, Eleazer S, Ruta V
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Progress toward a comprehensive brain protein interactome.
- Biochem Soc Trans - published February 1, 2025
- Dang V, Voigt B, Marcotte EM